Penn State Nittany Lions vs. Ohio State Buckeyes picks, predictions and odds for their Big Ten showdown on Saturday, October 31, 2020, at 7:30 p.m. ET from Beaver Stadium in State College, Pennsylvania. Direct from Las Vegas, our panel of professional sports handicappers look at the Vegas odds and give their college football football expert picks and predictions on the matchup between the Buckeyes and Nittany Lions. Current college football odds from Las Vegas have Ohio State as a -11.5 road favorite over Penn State, with the over/under sitting at 63.5 points.

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