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The American College of Toxicology podcast program, ToxChats ©, reports on cutting-edge news in toxicological research from around the globe.
Episodes & Posts
Episodes
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Transcribed
7 NOV 2025 · In this episode, Aimee Altemus and Adelaide Frimpong speak with Dr. Gary Miller of Columbia University, a widely recognized leader in exposome research. Dr. Miller discusses how the exposome—the full spectrum of environmental exposures throughout a lifetime—is transforming our approach to human and environmental health. He highlights how exposomics, data science, and toxicology contribute to Next Generation Risk Assessment strategies to more accurately predict disease risk and guide public health strategies. From innovative technologies to ethical implications, this conversation offers a compelling look at the future of health science in a complex and rapidly changing world.
Transcribed
15 OCT 2025 · In this compelling ToxChats podcast episode, hosts Kristin DeSouza and Michael Dorato speak with renowned drug development scientist Richard DiMarchi as he shares his deep understanding into the art and science of mentorship within the biomedical research community. Drawing from decades of experience, Dr. DiMarchi explores the evolving nature of mentorship and its critical role in shaping the next generation of innovators.
Richard DiMarchi shares powerful insights on setting clear expectations in mentor-mentee relationships, delivering constructive criticism with both empathy and precision, and speaking truth to power with integrity and professionalism. The conversation explores how mentorship is a two-way street—where learning flows in both directions and adapting mentorship styles to meet the diverse needs of mentees, as well as building confidence and resilience in emerging scientists, preparing them to lead with both competence and compassion.
Transcribed
30 SEP 2025 · Laid off—or worried you might be—and wondering what's next? In this episode, hosts Sunjay Sethi and Sarah Benjamin partner with the Early Career Professionals to demystify the post-layoff job search for early- to mid-career toxicologists. Kristin DeSouza and Terry Leyden are interviewed to talk about the hard stuff: quiet firing, the market that favors 10+ years’ experience or entry-level candidates, and then get practical about moving forward.
Transcribed
17 JUL 2025 · This podcast episode is designed to offer listeners a discussion about the FDA’s evolving stance on animal testing and exploring thoughts on its potential phase-out for monoclonal antibody (mAb) therapies. Hosted by Zac Lloyd and featuring expert insights from Dr. Whitney Helms, Executive Director of Nonclinical Development, Large Molecule Discovery at Eli Lilly and Company, and Dr. Diann Blanset, consultant at Akkeri, Inc., this roundtable-style discussion unpacks the scientific, ethical, and regulatory implications of this paradigm shift. Whether you're deep in the biologics pipeline or navigating the changing CRO landscape, this episode offers valuable perspectives on what the future may hold—and how to prepare for it.
Transcribed
7 JUL 2025 · In this episode, host Zac Lloyd engages with expert in the field Colleen Johnson to discuss critical considerations in designing in vivo nonclinical programs for dermal and topical products. Through this conversation we aim to enhance understanding of key aspects in this specialized area of toxicology. This podcast is designed to offer listeners an introduction to dermal product drug development.
Transcribed
23 JUN 2025 · In this episode, we speak with Jean-Philippe Therrien, a senior director of R&D, to discuss critical considerations in designing nonclinical programs for dermal and topical products. Through this conversation, we aim to enhance understanding of key aspects in this specialized area of toxicology. This podcast offers listeners an introduction to dermal product drug development.
Transcribed
5 MAY 2025 · In this episode, Dr. Katie Sokolowski and Dr. Tanya McDonnell sit down with Dr. Jessica Graham, a leader in the fields of occupational toxicology and product quality. During our time together, we discuss the current science of safety assessment, focusing on worker safety (occupational toxicology) and patient safety as it relates to pharmaceutical product quality. Dr. Graham explains key concepts in occupational toxicology as well as emerging tools and challenges. She also explores current strategies in managing impurities in therapeutics as well as the evolving regulatory requirements for pharmaceutical drug products. Dr. Graham conveys leading trends in alternative methods for hazard identification and risk assessment, shedding light on how these innovations are transforming human health hazard assessments in the areas of worker safety and impurity assessment. Whether you're a safety professional or just curious about the field, this episode offers essential insights into protecting workers, patients, and maintaining high industry standards.
Transcribed
1 APR 2025 · In this podcast, Dr. Derek Leishman discusses the development of regulatory guidance (ICH and GLP) for safety pharmacology studies. He follows this discussion with a conversation about nonclinical data predicting clinical outcomes, as well as potential changes to future regulatory updates to ICH guidance.
Transcribed
3 FEB 2025 · This podcast is part of a series on the different career paths in the field of toxicology. In this episode, we interview Dr. Alex Eapen on his career path to his current position as the Director of R&D Scientific & Regulatory Affairs – North America at Cargill. Dr. Eapen shares his experiences as a toxicologist in the food industry and the exciting opportunities this job brings to positively impact people's lives. In this episode, we also explore an overview of the responsibilities and the education requirements needed to pursue a career in toxicology in the food industry.
Transcribed
18 DEC 2024 · Not every drug that has reached human clinical trials has needed preliminary nonclinical studies to demonstrate safety. This podcast episode is a case study for replacing the use of animals during the safety testing that occurs prior to human clinical trials, in which our guest speaker reviews conversations with regulatory authorities regarding a modern nonanimal testing strategy utilized to bring a nonequine-derived antitoxin as a therapeutic product to a patient.
The American College of Toxicology podcast program, ToxChats ©, reports on cutting-edge news in toxicological research from around the globe.
Information
| Author | ACT ToxChats |
| Organization | ACT ToxChats |
| Categories | Science , Education |
| Website | www.spreaker.com |
| acthq@actox.org |
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