This episode is a group conversation with Deepak Keshwani, Professor and Associate Dean, Academic Programs, College of Engineering, Utah State University; Jenny Keshwani, Professor, Biological Engineering, Utah State University; and Marybeth Lima, P.E., Professor and Department Chair, Department of Agricultural & Biological Engineering, Louisiana State University, about why they propose a sixth CBSI principle should be added encompassing human-centric, non-extractive design. The group discusses mental models and how the sixth principle would be applied to designing circular bioeconomy systems.