For the first time this season, the Buffalo Bills find themselves not only humbled but searching for answers on both sides of the football.

Ryan Wolfe and John Cimino are back with an all-new Trust The Podcast, following Buffalo's 41-15 blowout loss on Sunday to the Indianapolis Colts.

Is the Bills season quickly reaching a crossroads? Is it time to hit the panic button? Where do the preseason Super Bowl favorites go from here?

Ryan and John investigate these questions, and more, on this week's podcast.

Listen in!