Sumoylation is a post-translational modification with the process that SUMO (small ubiquitin-like modifier) proteins are modified on substrate proteins catalyzed by an enzymatic cascade analogous to that involved in ubiquitination. In contrast to ubiquitin, SUMO is not used to tag proteins for degradation but can regulate various protein function including protein-protein interactions and subcellular localization. Sumoylation is also involved in a variety of cellular processes, such as transcriptional regulation, nuclear-cytosolic transport, apoptosis, protein stability, response to stress, and progression through the cell cycle. http://www.creative-biolabs.com/Sumoylation-Specific-Antibody-Production-Service.html