Newcastle United threw away a 2-0 lead and were left heartbroken thanks to a last minute Manchester United winner at Old Traffod.
The Magpies were two goals up within 10 minutes and went into the break on-top, and in control but saw their lead slip away before Alexis Sanchez grabbed the winner in the 91st minute.
Rafa Benitez's side now go into the international break still in the relegation zone and still looking for that first win of the season.
Kenedy opened the scoring in the seventh minute - curling in an effort from just inside the box. Yoshinori Muto made it two with a superb turn and shot past De Gea.
The Magpies then had chances to extend their lead with Muto, Jamaal Lascelles and Ayoze Perez guilty of not taking their chances.
Jose Mourinho changed things at half-time and Manchester United sparked into life with Paul Pogba free to pull the strings. But the Magpies continue to look for a third, Matt Ritchie and Kenedy going close before the Red Devils got one back.
Juan Mata scored with a free-kick on the edge of the box with 20 minutes to go. Anthony Martial then got the scores left with 15 minutes left before Alexis Sanchez rose at the death to nod in the winner.
Lee Ryder and Chris Waugh review the game from Old Trafford. For information regarding your data privacy, visit acast.com/privacy