29 APR 2024 · Buck Joffrey, MD, takes questions from the audience. Topics include human growth hormones, the potentially harmful effects of an MN, 40 Hz therapy, and visceral fat. Show Notes: 00:47 Is It Fine That I Sleep Too Much? 08:08 The 40hz Gamma Frequency and How It Relates to Brain Health 13:28 The Anti-Aging Effects of Human Growth Hormone 20:31 Reconsideration of How to Fast 29:22 Potentially Harmful Effect of NMN 33:08 Visceral vs Subcutaneous Fat  

22 APR 2024 · Buck Joffrey, MD, discusses the fasting regimen with Dr. Valter Longo, PhD. Dr. Longo is a world, renowned researcher in longevity and the author of: The Longevity Diet. Show Notes:  01:10 Types of Fasting 03:31 Why Fasting is Beneficial From a Cellular Level 07:00 Intermittent Fasting VS Fast Mimicking Diet 14:05 How Does Fasting Help Cancer Patients 20:37 What Is in the Fast Mimicking Diet 33:38 Pills and Supplements for Fasting Mimicking Diet 41:23 Time-Restricted Feeding Based on Circadian Rhythm  

15 APR 2024 · Buck Joffrey, MD interviews Robert Lufkin, MD about his book Lies I Taught in Medical School: And the Truths That Can Save Your Life Topics include metabolic syndrome, intermittent fasting, and various outdated information still used in mainstream medicine that may have deleterious effects on people’s health. Show Notes: 01:35 Dr. Lufkin’s Personal Journey to Question the Medicine Establishment 04:14 When Did People Start to Take Metabolic Syndrome Seriously? 08:33 What Exactly is Metabolic Syndrome from a Physiological Standpoint? 10:21 The Balance Between Building and Breaking Down in the Metabolic System 14:41 Time-Restricted Feeding and Ketogenic Diet 28:31 The Role of Medications and Supplements 30:51 Lifestyle and Exercise as Intervention  

8 APR 2024 · Dr. Buck Joffrey, M.D. interviews, Dr. Nathan Price, PhD from Thorne about a new paradigm in medicine driven by data, technology, and self-empowerment. Show Notes: 00:58 What Really is Healthspan? 05:06 Biological Age VS Chronological Age 07:41 The Factors that Determine Biological Aging 12:08 What Happens When You Artificially Suppress These Factors 16:58 What is Phenomics and how can it predict diseases? 24:21 How Can You Do Self Tests?

1 APR 2024 · In this April Fools special, Buck answers the burning questions of his number one fan, Phil Ferragamo.

25 MAR 2024 · In this episode of Sapio, Dr. Buck Joffrey, MD addresses the recent American Heart Association study correlating intermittent fasting/time restricted, feeding to higher rates of cardiovascular death. Buck breaks down what we already know about the data behind intermittent fasting in both animals and in humans and tries to put the most recent study into context. He provides feedback on the study itself, including some suggestions on how to use this new information. Show Notes: 02:01 Intermittent fasting vs caloric restriction 06:57 Why Intermittent Fasting Improves Metabolic Health 10:19 Intermittent fasting while maintaining a healthy diet 12:32 The study 19:35 What does this study mean to Buck?  

18 MAR 2024 · Buck Joffrey, MD talks to Romie Mushtaq, MD regarding stress, cortisol levels and prevention strategies including meditation and anti-inflammatory diets. Show Notes: 02:14 The definition of stress 13:16 Why does stress disrupt circadian rhythms and sleep 16:08 How do we treat stress? 21:23 Nootropics 24:39 Vagal nerve stimulator 28:34 Digital detox and meditation 33:02 Diet for stress  

11 MAR 2024 · Buck Joffrey MD speaks to Justin Houman MD who is a urologist regarding the idea of aggressive testosterone treatment to decrease the risk of metabolic syndrome and therefore multiple other disease processes that are downstream. Other topics disgust include erectile dysfunction, early treatment with ED meds and the correlation with Alzheimer’s disease. Show Notes: 1:27 Is it true that the testosterone in men in general has gone down? 02:43 Common symptoms of love testosterone 05:15 Normal level of testosterone 07:19 Testosterone and metabolic syndrome 12:49 Testosterone replacement therapy and cancer 16:03 Downside of testosterone replacement therapy 19:18 Different options to supplement testosterone 29:03 What’s on the horizon? 32:50 ED and cardiovascular diseases 38:35 Should all 40+ men be on daily Cialis? 40:43 Penile pump  

4 MAR 2024 · Buck Joffrey, MD and Linda Tyler, PhD discuss the topic of plant-based only/Vegan diets. The conversation includes topics on inflammation and nutritional concerns. Show Notes: 2:55 A plant-based diet for better health? 11:53 Balancing nutritions for the plant-based diet 20:39 Accessibility of the plant-based diet 22:30 Processed plant-based food  

26 FEB 2024 · Buck Joffrey, MD interviews Anoop Kumar, MD on his perspective on health and wellness. Dr. Kumar is an emergency medicine doctor who is also knowledgeable about traditional Indian Philosophy and medicine. Show Notes: 00:43 Near-Death Experience and Shift in Perspective 07:04 The Three Minds Framework 23:03 Reevaluating the Model of Human Anatomy 27:20 The Four Engines: Nutrition, Movement, Connection, and Rest 39:24 The Four Engines of Health and Healing 41:01 Harnessing the Placebo Effect and Self-Healing