24 APR 2024 · This episode explores the complex relationship between popular weight loss drugs like Ozempic, Wegovy, and Mounjaro and their impact on various aspects of an individual's life. It delves into how these medications work, their potential effects on libido, personality, and overall well-being, and the importance of a comprehensive approach to weight loss that includes lifestyle changes, medical supervision, and mental health support. The article also discusses the role of social media in shaping public perception and the need for realistic expectations when considering these drugs as part of a weight loss journey.

18 MAR 2024 · This episode takes a deep dive into Oprah Winfrey's radical new weight loss approach - her embrace of the controversial drug Ozempic and other GLP-1 medications. It explores the science behind these groundbreaking pills, examines celebrity confessions about using them, and investigates the potential economic impacts if their popularity continues to surge. The episode also addresses the risks, side effects, and ethical debates surrounding weight loss drugs. With Oprah leading the charge, this chronicles a revolution that could reshape how we view obesity and weight management forever.

21 FEB 2024 · This episode examines the explosive popularity of the diabetes drug Ozempic for off-label use as a weight loss injection. It contrasts skeptical perspectives on this trend from celebrities like Rob Lowe with enthusiastic endorsements from stars such as Kelly Osbourne. Additionally, it delves into the massive unregulated gray market for Ozempic that has emerged in China among its hundreds of millions of overweight and obese citizens, fueled by social media influencers and e-commerce. With domestic and global demand skyrocketing, the piece explores issues around patent protections, supply shortages, the rush to develop lower-potency generic alternatives, and the overall controversy inherent to using medicines intended for chronic illness as cosmetic aids.

24 JAN 2024 · This episode explores how the diabetes medication Ozempic became an overnight weight loss sensation – and the rippling impacts its popularity is having across medicine, culture, and the economy. We dive into research on Ozempic's efficacy against obesity, the soaring demand making access difficult amid shortages, employers scrambling to add coverage given employees’ intense interest, and larger questions around what our fixation with a weight loss drug says about beauty norms and healthcare policy in America.

8 JAN 2024 · A major new study finds popular diabetes and weight loss drugs Ozempic and Wegovy, which contain the ingredient semaglutide, actually carry a lower risk of suicidal thoughts compared to other medications used to treat obesity and type 2 diabetes. However, the FDA is still investigating potential mental health side effects, so more long-term data is needed.

27 DEC 2023 · Overdoses involving weight-loss drugs like Ozempic have surged 1,500% in the past five years, with nearly 3,000 calls to America's Poison Centers this year, compared to just 196 in 2019. Most cases involve compounded versions of the drug, often leading to accidental overdoses, as opposed to the pharmaceutical-grade product. Patients experiencing overdoses face severe symptoms, with many in their 60s. The rise in demand for these drugs, coupled with shortages, has led to pharmacies producing unapproved versions, raising concerns. Official Ozempic pens have built-in safeguards, while compounded versions can lead to user errors.

20 DEC 2023 · Ozempic, a diabetes drug used for weight loss, varies in effectiveness among individuals. It mimics hormones to reduce appetite and slow stomach emptying. Some experience significant weight loss, but others hit a plateau where it seems to stop working. Stronger weight-loss drugs and ongoing research offer hope for those facing Ozempic resistance, but weight management remains a complex challenge.

14 DEC 2023 · Doctors caution against skipping diabetes and weight loss injections like Ozempic and Wegovy for Thanksgiving indulgence, as it can lead to health issues like weight gain and elevated blood sugar levels. Diabetics, in particular, risk dangerous glucose spikes. Experts recommend finding a balance by making healthier food choices during the holidays and avoiding extended medication breaks to maintain progress and minimize complications.

2 DEC 2023 · Research suggests that medications like Ozempic and Wegovy, designed for weight loss and diabetes management, may have an unexpected benefit: reducing alcohol cravings. Over the past decade, these drugs, known as GLP-1 receptor agonists, have shown promise in diminishing alcohol intake. Studies involving earlier medications like exenatide hinted at this effect, and recent research with semaglutide (Ozempic) is strengthening the case for their potential use in treating alcohol use disorder (AUD).Despite initial mixed results in trials, recent studies have demonstrated reduced AUD symptoms in individuals prescribed semaglutide, even when weight loss was minimal. The exact mechanism by which these drugs curb alcohol cravings remains unclear but is believed to involve brain pathways linked to appetite regulation and reward.While clinical trials are ongoing, it's important to note that established treatments like naltrexone, disulfiram, and acamprosate are available for AUD. Experts caution against hasty adoption of GLP-1 receptor agonists for AUD treatment until more research is conducted, emphasizing the need for further clinical data to confirm their efficacy. Nevertheless, the accidental discovery of these drugs' potential in curbing alcohol cravings among individuals using them for other conditions suggests a promising avenue in addiction treatment.

18 NOV 2023 · Sharon Osbourne's experience with Ozempic, a type 2 diabetes medication sometimes used for weight loss, is recounted. Sharon warns against using it solely for weight loss after dropping 42 pounds, expressing concern about her current weight of under 100 pounds. She advises caution, particularly with teenagers, as the drug can lead to dangerous weight loss and potential addiction.The narrative also touches on the experiences of other celebrities like Amy Schumer, Sophie Turner, Chelsea Handler, and Khloe Kardashian, who have shared their encounters with Ozempic. Schumer criticized celebrities for not being transparent about its use, Turner expressed her disapproval of the drug's advertisements, Handler revealed she unwittingly tried it and later gave it away, and Kardashian defended her workout regimen against speculation. Overall, the piece emphasizes the importance of responsible and informed choices when considering medications for weight management.