This week we speak with living legend of cardiology, Dr. Michael Freed about his life and also his landmark paper in 1981 on PGE1. How did Dr. Freed come to conduct one of the first multi center trials of an agent in pediatrics? What was life like in the world of pediatric cardiology prior to PGE1? What is Dr. Freed up to today? What advice does he have for the younger generation? This is a rare opportunity to speak with one of the living legends of our field. DOI: 10.1161/01.cir.64.5.899