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<rss xmlns:itunes="http://www.itunes.com/dtds/podcast-1.0.dtd" xmlns:atom="http://www.w3.org/2005/Atom" xmlns:podcast="https://podcastindex.org/namespace/1.0" xmlns:media="http://search.yahoo.com/mrss/" version="2.0"><channel><title>Beta Finch - Gilead Sciences - GILD - EN</title><link>https://betafinch.com</link><description><![CDATA[AI-powered earnings call analysis for Gilead Sciences (GILD). Two AI hosts break down quarterly results, key metrics, and market implications in digestible podcast episodes.]]></description><atom:link href="https://www.spreaker.com/show/6882085/episodes/feed" rel="self" type="application/rss+xml"/><language>en</language><category>Investing</category><copyright>2026 Beta Finch</copyright><image><url>https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/b5d47710cff47d2633c270bf330bc928.jpg</url><title>Beta Finch - Gilead Sciences - GILD - EN</title><link>https://betafinch.com</link></image><lastBuildDate>Wed, 16 Sep 2026 13:33:31 +0000</lastBuildDate><itunes:author>Beta Finch</itunes:author><itunes:owner><itunes:name>Beta Finch</itunes:name><itunes:email>contact@betafinch.com</itunes:email></itunes:owner><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/b5d47710cff47d2633c270bf330bc928.jpg"/><itunes:subtitle>AI-powered earnings call analysis for Gilead Sciences (GILD). Two AI hosts break down quarterly results, key metrics, and market implications in digestible podcast episodes.</itunes:subtitle><itunes:summary><![CDATA[AI-powered earnings call analysis for Gilead Sciences (GILD). Two AI hosts break down quarterly results, key metrics, and market implications in digestible podcast episodes.]]></itunes:summary><itunes:category text="Business"><itunes:category text="Investing"/></itunes:category><itunes:explicit>false</itunes:explicit><podcast:guid>f3276642-b461-5176-8400-12e16ae64b6b</podcast:guid><podcast:txt purpose="ai-content">true</podcast:txt><itunes:type>episodic</itunes:type><item><title>Gilead Sciences Q2 2026 Earnings Analysis</title><link>https://www.spreaker.com/episode/gilead-sciences-q2-2026-earnings-analysis--74741480</link><description><![CDATA[More earnings analysis: <a href="https://betafinch.com" rel="noopener">https://betafinch.com</a><br />Groups: PHARMA (<a href="https://betafinch.com/groups/PHARMA)" rel="noopener">https://betafinch.com/groups/PHARMA)</a><br />──────────<br />ALEX: Welcome to Beta Finch, your AI-powered earnings breakdown! Today we're diving into Gilead Sciences' second quarter 2026 results — and Jordan, this is a big one.<br /><br />JORDAN: It really is. Big numbers, big acquisitions, big pipeline news.<br /><br />ALEX: Before we get into it, quick disclaimer: this podcast is AI-generated content for educational and entertainment purposes only. Nothing we discuss should be considered investment advice. Always do your own research and consult a qualified financial advisor before making any investment decisions.<br /><br />JORDAN: Good to have that out there. Okay, let's talk numbers. Gilead's base business — that's total product sales excluding the COVID drug Veklury — came in at $7.6 billion, up 10% year-over-year. That's their strongest second-quarter growth in three years.<br /><br />ALEX: And it's broad-based too. HIV sales were up 12% to $5.7 billion, Trodelvy in oncology up 26%, and Livdelzi in liver disease more than doubled. On the back of that, management raised full-year HIV growth guidance to 9-10%, up from 8%.<br /><br />JORDAN: The headline stat for me was PrEP — that's HIV prevention. Quarterly PrEP sales topped $1 billion for the first time, doubling year-over-year, putting that business on a $4 billion annual run rate. Yeztugo, their twice-yearly injectable, is now the leading option for new PrEP starts and even leads the switch market after just four quarters on the market.<br /><br />ALEX: And they shared something pretty striking — more than 70% of Yeztugo patients are coming back for their second injection at six months, meaning they get a full year of protection. That persistency rate is apparently well above anything else in the category.<br /><br />JORDAN: Now, EPS is where things get messy — but for a good reason. Non-GAAP diluted EPS was actually negative $6.75 for the quarter.<br /><br />ALEX: Wait, negative? That sounds alarming.<br /><br />JORDAN: It sounds alarming, but it's really an accounting story. Gilead closed three acquisitions this quarter — Arcellx, Tubulis, and Ouro Medicines — totaling about $11.2 billion in acquired R&D expense, which under accounting rules gets taken as a hit all at once. Strip that out, along with a one-time non-cash revenue item, and EPS was actually $2.27 for the quarter — up about 13% year-over-year on an apples-to-apples basis. That's outpacing revenue growth, which tells you there's real operating leverage in this business.<br /><br />ALEX: Right, and full-year guidance reflects that same split — they're now guiding to $30.1 to $30.4 billion in total product sales, raised from prior guidance, but full-year EPS on a GAAP-ish basis is guided negative because of those acquisition costs. Excluding the deal noise, full-year EPS guidance is $8.50 to $8.85, actually raised slightly on the low end.<br /><br />JORDAN: So the deals are the real story of the quarter, strategically speaking. Let's unpack them. Arcellx gives Gilead full ownership of anito-cel, their multiple myeloma cell therapy — that's five months from its PDUFA date, so a launch is coming. Tubulis brings an antibody-drug-conjugate platform, and there's already exciting early data on GS-8824 in ovarian cancer — 61% response rate in a tough, pretreated population.<br /><br />ALEX: And on the existing portfolio side, it wasn't just an acquisitions quarter. Trodelvy got approved for first-line metastatic triple-negative breast cancer, roughly doubling its addressable patient population. Livdelzi, the liver disease drug, posted positive phase III data that could expand its use. And they launched Hepcludex, the first-ever approved treatment for chronic hepatitis D.<br /><br />JORDAN: One thing that jumped out in the Q&A — an analyst pushed CEO Dan O'Day on whether Gilead still cares about diversifying away from HIV, since HIV remains such a dominant chunk of revenue. His answer was basically "yes, but we're doing it two ways" — diversifying within HIV itself with new dosing options, dai<br /><br />This episode includes AI-generated content.]]></description><guid isPermaLink="false">GILD-Q2-2026-en</guid><pubDate>Sat, 29 Aug 2026 01:26:31 +0000</pubDate><enclosure url="https://dts.podtrac.com/redirect.mp3/api.spreaker.com/download/episode/74741480/gild_2026_q2_5bab28_en.mp3" length="6808748" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/af43c9f8-67e1-4e8f-8bc6-21bccf8397bb/af43c9f8-67e1-4e8f-8bc6-21bccf8397bb.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/af43c9f8-67e1-4e8f-8bc6-21bccf8397bb/af43c9f8-67e1-4e8f-8bc6-21bccf8397bb.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/af43c9f8-67e1-4e8f-8bc6-21bccf8397bb/af43c9f8-67e1-4e8f-8bc6-21bccf8397bb.vtt" type="text/vtt" language="en"/><podcast:txt purpose="ai-content">true</podcast:txt><itunes:author>Beta Finch</itunes:author><itunes:subtitle>More earnings analysis: https://betafinch.com
Groups: PHARMA (https://betafinch.com/groups/PHARMA)
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ALEX: Welcome to Beta Finch, your AI-powered earnings breakdown! Today we're diving into Gilead Sciences' second quarter 2026 results — and...</itunes:subtitle><itunes:summary><![CDATA[More earnings analysis: <a href="https://betafinch.com" rel="noopener">https://betafinch.com</a><br />Groups: PHARMA (<a href="https://betafinch.com/groups/PHARMA)" rel="noopener">https://betafinch.com/groups/PHARMA)</a><br />──────────<br />ALEX: Welcome to Beta Finch, your AI-powered earnings breakdown! Today we're diving into Gilead Sciences' second quarter 2026 results — and Jordan, this is a big one.<br /><br />JORDAN: It really is. Big numbers, big acquisitions, big pipeline news.<br /><br />ALEX: Before we get into it, quick disclaimer: this podcast is AI-generated content for educational and entertainment purposes only. Nothing we discuss should be considered investment advice. Always do your own research and consult a qualified financial advisor before making any investment decisions.<br /><br />JORDAN: Good to have that out there. Okay, let's talk numbers. Gilead's base business — that's total product sales excluding the COVID drug Veklury — came in at $7.6 billion, up 10% year-over-year. That's their strongest second-quarter growth in three years.<br /><br />ALEX: And it's broad-based too. HIV sales were up 12% to $5.7 billion, Trodelvy in oncology up 26%, and Livdelzi in liver disease more than doubled. On the back of that, management raised full-year HIV growth guidance to 9-10%, up from 8%.<br /><br />JORDAN: The headline stat for me was PrEP — that's HIV prevention. Quarterly PrEP sales topped $1 billion for the first time, doubling year-over-year, putting that business on a $4 billion annual run rate. Yeztugo, their twice-yearly injectable, is now the leading option for new PrEP starts and even leads the switch market after just four quarters on the market.<br /><br />ALEX: And they shared something pretty striking — more than 70% of Yeztugo patients are coming back for their second injection at six months, meaning they get a full year of protection. That persistency rate is apparently well above anything else in the category.<br /><br />JORDAN: Now, EPS is where things get messy — but for a good reason. Non-GAAP diluted EPS was actually negative $6.75 for the quarter.<br /><br />ALEX: Wait, negative? That sounds alarming.<br /><br />JORDAN: It sounds alarming, but it's really an accounting story. Gilead closed three acquisitions this quarter — Arcellx, Tubulis, and Ouro Medicines — totaling about $11.2 billion in acquired R&D expense, which under accounting rules gets taken as a hit all at once. Strip that out, along with a one-time non-cash revenue item, and EPS was actually $2.27 for the quarter — up about 13% year-over-year on an apples-to-apples basis. That's outpacing revenue growth, which tells you there's real operating leverage in this business.<br /><br />ALEX: Right, and full-year guidance reflects that same split — they're now guiding to $30.1 to $30.4 billion in total product sales, raised from prior guidance, but full-year EPS on a GAAP-ish basis is guided negative because of those acquisition costs. Excluding the deal noise, full-year EPS guidance is $8.50 to $8.85, actually raised slightly on the low end.<br /><br />JORDAN: So the deals are the real story of the quarter, strategically speaking. Let's unpack them. Arcellx gives Gilead full ownership of anito-cel, their multiple myeloma cell therapy — that's five months from its PDUFA date, so a launch is coming. Tubulis brings an antibody-drug-conjugate platform, and there's already exciting early data on GS-8824 in ovarian cancer — 61% response rate in a tough, pretreated population.<br /><br />ALEX: And on the existing portfolio side, it wasn't just an acquisitions quarter. Trodelvy got approved for first-line metastatic triple-negative breast cancer, roughly doubling its addressable patient population. Livdelzi, the liver disease drug, posted positive phase III data that could expand its use. And they launched Hepcludex, the first-ever approved treatment for chronic hepatitis D.<br /><br />JORDAN: One thing that jumped out in the Q&A — an...]]></itunes:summary><itunes:duration>426</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/b5d47710cff47d2633c270bf330bc928.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>Gilead Sciences Q1 2026 Earnings Analysis</title><link>https://www.spreaker.com/episode/gilead-sciences-q1-2026-earnings-analysis--71925311</link><description><![CDATA[More earnings analysis: <a href="https://betafinch.com" rel="noopener">https://betafinch.com</a><br />Groups: PHARMA (<a href="https://betafinch.com/groups/PHARMA)" rel="noopener">https://betafinch.com/groups/PHARMA)</a><br />──────────<br />**Beta Finch Podcast Script - Gilead Q1 2026 Earnings**<br /><br />---<br /><br />**ALEX:** Welcome to Beta Finch, your AI-powered earnings breakdown! I'm Alex, and I'm joined as always by my co-host Jordan. Today we're diving into Gilead Sciences' first quarter 2026 results - and wow, what a quarter this was for the biotech giant.<br /><br />Before we jump in, I need to mention that this podcast is AI-generated content for educational and entertainment purposes only. Nothing we discuss should be considered investment advice. Always do your own research and consult a qualified financial advisor before making any investment decisions.<br /><br />Jordan, Gilead came out swinging with some pretty impressive numbers, didn't they?<br /><br />**JORDAN:** Absolutely, Alex! Let's start with the headline numbers because they're quite strong. Total product sales hit $6.9 billion, up 5% year-over-year. But here's the kicker - if you exclude their COVID drug Veklury, their base business grew 8% to $6.8 billion. That's solid growth for a company Gilead's size.<br /><br />**ALEX:** And they're not just talking the talk - they're raising guidance across the board. What stood out to you most about their updated outlook?<br /><br />**JORDAN:** The HIV business is absolutely on fire. They raised their HIV growth expectations from 6% to 8% for the full year, and get this - their PrEP drug Yes2Go, which prevents HIV, is now expected to hit $1 billion in sales. That would make it a blockbuster drug in just its first full year on the market!<br /><br />**ALEX:** That's remarkable. Let's break down what's driving this HIV success, because it seems like Gilead is firing on all cylinders here.<br /><br />**JORDAN:** It really is a multi-pronged success story. Their flagship HIV treatment Biktarvy continues to dominate with over 52% market share in the U.S. - that's a drug pulling in $3.4 billion in the quarter alone. But the real star is Yes2Go, their twice-yearly injectable HIV prevention drug. Sales jumped 72% just from the previous quarter to $166 million.<br /><br />**ALEX:** And during the Q&A, management seemed pretty confident about Yes2Go's trajectory. What are they seeing that makes them so optimistic?<br /><br />**JORDAN:** Great question! Johanna Mercier, their commercial chief, mentioned some really encouraging metrics. They now have 95% insurance coverage with 95% of those having zero copay for patients. They're seeing strong uptake from both people switching from other drugs and completely new users. And perhaps most importantly, the "persistency" - meaning people coming back for their second injection - is looking really good.<br /><br />**ALEX:** Now, Gilead wasn't just focused on HIV this quarter. They made some major acquisition moves. Can you walk us through what they're buying and why?<br /><br />**JORDAN:** This is where it gets really interesting from a strategic perspective. They closed three major deals: Arcellx for their cancer cell therapy anitocel, they're buying Tubulis for their antibody-drug conjugate technology, and Oral Medicines for autoimmune treatments. The total upfront cost? About $11.5 billion.<br /><br />**ALEX:** That's a lot of cash! How are investors supposed to think about these deals?<br /><br />**JORDAN:** Well, it's definitely impacting their near-term earnings - they're actually projecting a loss per share for 2026 because of these upfront costs. But management seemed confident these are strategic investments for the long term. The Arcellx deal brings them anitocel, which they believe could be best-in-class for multiple myeloma. And Tubulis gives them next-generation cancer drug technology that goes beyond their current Trodelvy franchise.<br /><br />**ALEX:** Speaking of Trodelvy, how's their existing oncology business performing?<br /><br />**JORDAN:** Trodelvy is growing nicely - up 37% year-over-year to $402 million. They're expecting regulatory decisions this year that could expand its use to first-line breast cancer treatment, which would be a significant ma<br /><br />This episode includes AI-generated content.]]></description><guid isPermaLink="false">GILD-Q1-2026-en</guid><pubDate>Fri, 08 May 2026 15:39:38 +0000</pubDate><enclosure url="https://dts.podtrac.com/redirect.mp3/api.spreaker.com/download/episode/71925311/gild_2026_q1_0b5a0c_en.mp3" length="8322029" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/b5c50cc3-8512-4581-bc13-abba5051dc6b/b5c50cc3-8512-4581-bc13-abba5051dc6b.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/b5c50cc3-8512-4581-bc13-abba5051dc6b/b5c50cc3-8512-4581-bc13-abba5051dc6b.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/b5c50cc3-8512-4581-bc13-abba5051dc6b/b5c50cc3-8512-4581-bc13-abba5051dc6b.vtt" type="text/vtt" language="en"/><podcast:txt purpose="ai-content">true</podcast:txt><itunes:author>Beta Finch</itunes:author><itunes:subtitle>More earnings analysis: https://betafinch.com
Groups: PHARMA (https://betafinch.com/groups/PHARMA)
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**Beta Finch Podcast Script - Gilead Q1 2026 Earnings**

---

**ALEX:** Welcome to Beta Finch, your AI-powered earnings breakdown! I'm Alex,...</itunes:subtitle><itunes:summary><![CDATA[More earnings analysis: <a href="https://betafinch.com" rel="noopener">https://betafinch.com</a><br />Groups: PHARMA (<a href="https://betafinch.com/groups/PHARMA)" rel="noopener">https://betafinch.com/groups/PHARMA)</a><br />──────────<br />**Beta Finch Podcast Script - Gilead Q1 2026 Earnings**<br /><br />---<br /><br />**ALEX:** Welcome to Beta Finch, your AI-powered earnings breakdown! I'm Alex, and I'm joined as always by my co-host Jordan. Today we're diving into Gilead Sciences' first quarter 2026 results - and wow, what a quarter this was for the biotech giant.<br /><br />Before we jump in, I need to mention that this podcast is AI-generated content for educational and entertainment purposes only. Nothing we discuss should be considered investment advice. Always do your own research and consult a qualified financial advisor before making any investment decisions.<br /><br />Jordan, Gilead came out swinging with some pretty impressive numbers, didn't they?<br /><br />**JORDAN:** Absolutely, Alex! Let's start with the headline numbers because they're quite strong. Total product sales hit $6.9 billion, up 5% year-over-year. But here's the kicker - if you exclude their COVID drug Veklury, their base business grew 8% to $6.8 billion. That's solid growth for a company Gilead's size.<br /><br />**ALEX:** And they're not just talking the talk - they're raising guidance across the board. What stood out to you most about their updated outlook?<br /><br />**JORDAN:** The HIV business is absolutely on fire. They raised their HIV growth expectations from 6% to 8% for the full year, and get this - their PrEP drug Yes2Go, which prevents HIV, is now expected to hit $1 billion in sales. That would make it a blockbuster drug in just its first full year on the market!<br /><br />**ALEX:** That's remarkable. Let's break down what's driving this HIV success, because it seems like Gilead is firing on all cylinders here.<br /><br />**JORDAN:** It really is a multi-pronged success story. Their flagship HIV treatment Biktarvy continues to dominate with over 52% market share in the U.S. - that's a drug pulling in $3.4 billion in the quarter alone. But the real star is Yes2Go, their twice-yearly injectable HIV prevention drug. Sales jumped 72% just from the previous quarter to $166 million.<br /><br />**ALEX:** And during the Q&A, management seemed pretty confident about Yes2Go's trajectory. What are they seeing that makes them so optimistic?<br /><br />**JORDAN:** Great question! Johanna Mercier, their commercial chief, mentioned some really encouraging metrics. They now have 95% insurance coverage with 95% of those having zero copay for patients. They're seeing strong uptake from both people switching from other drugs and completely new users. And perhaps most importantly, the "persistency" - meaning people coming back for their second injection - is looking really good.<br /><br />**ALEX:** Now, Gilead wasn't just focused on HIV this quarter. They made some major acquisition moves. Can you walk us through what they're buying and why?<br /><br />**JORDAN:** This is where it gets really interesting from a strategic perspective. They closed three major deals: Arcellx for their cancer cell therapy anitocel, they're buying Tubulis for their antibody-drug conjugate technology, and Oral Medicines for autoimmune treatments. The total upfront cost? About $11.5 billion.<br /><br />**ALEX:** That's a lot of cash! How are investors supposed to think about these deals?<br /><br />**JORDAN:** Well, it's definitely impacting their near-term earnings - they're actually projecting a loss per share for 2026 because of these upfront costs. But management seemed confident these are strategic investments for the long term. The Arcellx deal brings them anitocel, which they believe could be best-in-class for multiple myeloma. And Tubulis gives them next-generation cancer drug technology that goes beyond their current Trodelvy franchise.<br /><br />**ALEX:**...]]></itunes:summary><itunes:duration>521</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/b5d47710cff47d2633c270bf330bc928.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>Gilead Sciences Q4 2025 Earnings Analysis</title><link>https://www.spreaker.com/episode/gilead-sciences-q4-2025-earnings-analysis--70248742</link><description><![CDATA[# Beta Finch Podcast Script: Gilead Q4 2025 Earnings<br /><br />**ALEX:** Welcome to Beta Finch, your AI-powered earnings breakdown where we dive deep into the numbers that move markets. I'm Alex, and as always, I'm joined by my co-host Jordan. Today we're unpacking Gilead Sciences' Q4 2025 results - and folks, there's a lot to dig into here.<br /><br />Before we jump in though, I need to mention that this podcast is AI-generated content for educational and entertainment purposes only. Nothing we discuss should be considered investment advice. Always do your own research and consult a qualified financial advisor before making any investment decisions.<br /><br />**JORDAN:** Thanks Alex. And what a quarter this was for Gilead! The biotech giant just wrapped up what CEO Dan O'Day called "a remarkable year" - and the numbers certainly back that up. They hit $28.9 billion in total product sales for 2025, beating their guidance range and showing some serious momentum heading into 2026.<br /><br />**ALEX:** Absolutely, Jordan. Let's break down those headline numbers first. Total product sales came in at $7.9 billion for Q4, up 5% year-over-year. But here's what caught my attention - when you strip out their COVID drug Veclury, which has been declining as expected, their base business actually grew 7% in the quarter and 4% for the full year.<br /><br />**JORDAN:** That's a key distinction, Alex. And speaking of key numbers, their HIV business - which is still their cash cow - delivered $20.8 billion in sales for the year, up 6%. But here's where it gets interesting: they faced an estimated $900 million headwind from Medicare Part D redesign changes. Without that policy impact, their HIV business would have grown 10%.<br /><br />**ALEX:** That Medicare Part D impact is huge context, Jordan. For listeners who might not be familiar, this was a policy change that affected how drug pricing works for seniors on Medicare. So when Gilead says their underlying HIV business grew 10%, that's actually pretty impressive growth for what's considered a mature market.<br /><br />**JORDAN:** Exactly. And let's talk about the star of the show - YES2GO. This is their twice-yearly injectable HIV prevention drug that launched in 2025, and it's already showing blockbuster potential. They did $150 million in sales for the year, and here's the kicker - they're guiding for $800 million in 2026.<br /><br />**ALEX:** That's more than a 5x increase, Jordan. During the Q&A, analysts were really pressing on how realistic that number is. Management seems confident though, citing 90% payer coverage already - including all major insurers - with about 90% of covered patients getting it with zero co-pay.<br /><br />**JORDAN:** The coverage piece is critical, Alex. Commercial launch is one thing, but getting insurance companies to pay for a premium-priced injectable is another. The fact that they hit their 90% coverage target well ahead of their one-year timeline suggests the value proposition is resonating with payers.<br /><br />**ALEX:** Let's shift to their pipeline, because this is where things get really interesting for long-term investors. They have four potential product launches coming in 2026, plus five Phase III data readouts across HIV, cancer, and liver disease.<br /><br />**JORDAN:** Right, and this diversification strategy is really starting to pay off. Their cancer drug Trodelvy grew 6% to $1.4 billion, and they just got positive Phase III data that could expand it from second-line to first-line treatment in triple-negative breast cancer. That's potentially doubling the addressable market.<br /><br />**ALEX:** And Trodelvy isn't their only oncology play. They're preparing to launch something called Anidocel - a CAR-T therapy for multiple myeloma. The clinical data looks strong with a 96% overall response rate and what they're calling a "best-in-disease" safety profile.<br /><br />**JORDAN:** The safety piece is huge in CAR-T, Alex. These are powerful but potentially toxic treatments. If they can deliver the efficacy without the severe side effects, that's a real competitive advant<br /><br />This episode includes AI-generated content.]]></description><guid isPermaLink="false">GILD-Q4-2025-en</guid><pubDate>Tue, 24 Feb 2026 13:06:36 +0000</pubDate><enclosure url="https://dts.podtrac.com/redirect.mp3/api.spreaker.com/download/episode/70248742/gild_2025_q4_f8aa92_en.mp3" length="8349196" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/16d56f41-2fe3-4e1d-8940-a6a4129cb4f0/16d56f41-2fe3-4e1d-8940-a6a4129cb4f0.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/16d56f41-2fe3-4e1d-8940-a6a4129cb4f0/16d56f41-2fe3-4e1d-8940-a6a4129cb4f0.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/16d56f41-2fe3-4e1d-8940-a6a4129cb4f0/16d56f41-2fe3-4e1d-8940-a6a4129cb4f0.vtt" type="text/vtt" language="en"/><podcast:txt purpose="ai-content">true</podcast:txt><itunes:author>Beta Finch</itunes:author><itunes:subtitle># Beta Finch Podcast Script: Gilead Q4 2025 Earnings

**ALEX:** Welcome to Beta Finch, your AI-powered earnings breakdown where we dive deep into the numbers that move markets. I'm Alex, and as always, I'm joined by my co-host Jordan. Today we're...</itunes:subtitle><itunes:summary><![CDATA[# Beta Finch Podcast Script: Gilead Q4 2025 Earnings<br /><br />**ALEX:** Welcome to Beta Finch, your AI-powered earnings breakdown where we dive deep into the numbers that move markets. I'm Alex, and as always, I'm joined by my co-host Jordan. Today we're unpacking Gilead Sciences' Q4 2025 results - and folks, there's a lot to dig into here.<br /><br />Before we jump in though, I need to mention that this podcast is AI-generated content for educational and entertainment purposes only. Nothing we discuss should be considered investment advice. Always do your own research and consult a qualified financial advisor before making any investment decisions.<br /><br />**JORDAN:** Thanks Alex. And what a quarter this was for Gilead! The biotech giant just wrapped up what CEO Dan O'Day called "a remarkable year" - and the numbers certainly back that up. They hit $28.9 billion in total product sales for 2025, beating their guidance range and showing some serious momentum heading into 2026.<br /><br />**ALEX:** Absolutely, Jordan. Let's break down those headline numbers first. Total product sales came in at $7.9 billion for Q4, up 5% year-over-year. But here's what caught my attention - when you strip out their COVID drug Veclury, which has been declining as expected, their base business actually grew 7% in the quarter and 4% for the full year.<br /><br />**JORDAN:** That's a key distinction, Alex. And speaking of key numbers, their HIV business - which is still their cash cow - delivered $20.8 billion in sales for the year, up 6%. But here's where it gets interesting: they faced an estimated $900 million headwind from Medicare Part D redesign changes. Without that policy impact, their HIV business would have grown 10%.<br /><br />**ALEX:** That Medicare Part D impact is huge context, Jordan. For listeners who might not be familiar, this was a policy change that affected how drug pricing works for seniors on Medicare. So when Gilead says their underlying HIV business grew 10%, that's actually pretty impressive growth for what's considered a mature market.<br /><br />**JORDAN:** Exactly. And let's talk about the star of the show - YES2GO. This is their twice-yearly injectable HIV prevention drug that launched in 2025, and it's already showing blockbuster potential. They did $150 million in sales for the year, and here's the kicker - they're guiding for $800 million in 2026.<br /><br />**ALEX:** That's more than a 5x increase, Jordan. During the Q&A, analysts were really pressing on how realistic that number is. Management seems confident though, citing 90% payer coverage already - including all major insurers - with about 90% of covered patients getting it with zero co-pay.<br /><br />**JORDAN:** The coverage piece is critical, Alex. Commercial launch is one thing, but getting insurance companies to pay for a premium-priced injectable is another. The fact that they hit their 90% coverage target well ahead of their one-year timeline suggests the value proposition is resonating with payers.<br /><br />**ALEX:** Let's shift to their pipeline, because this is where things get really interesting for long-term investors. They have four potential product launches coming in 2026, plus five Phase III data readouts across HIV, cancer, and liver disease.<br /><br />**JORDAN:** Right, and this diversification strategy is really starting to pay off. Their cancer drug Trodelvy grew 6% to $1.4 billion, and they just got positive Phase III data that could expand it from second-line to first-line treatment in triple-negative breast cancer. That's potentially doubling the addressable market.<br /><br />**ALEX:** And Trodelvy isn't their only oncology play. They're preparing to launch something called Anidocel - a CAR-T therapy for multiple myeloma. The clinical data looks strong with a 96% overall response rate and what they're calling a "best-in-disease" safety profile.<br /><br />**JORDAN:** The safety piece is huge in CAR-T, Alex. These are...]]></itunes:summary><itunes:duration>522</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/b5d47710cff47d2633c270bf330bc928.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>Coming Soon - Beta Finch EN</title><link>https://www.spreaker.com/episode/coming-soon-beta-finch-en--70092103</link><description><![CDATA[Stay tuned for AI-powered earnings analysis from Beta Finch.<br /><br />This episode includes AI-generated content.]]></description><guid isPermaLink="false">GILD-coming-soon-en</guid><pubDate>Tue, 17 Feb 2026 04:45:39 +0000</pubDate><enclosure url="https://dts.podtrac.com/redirect.mp3/api.spreaker.com/download/episode/70092103/coming_soon_en.mp3" length="1933104" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/9571e8d1-e6ec-4ddf-a5ff-a37241bb9b85/9571e8d1-e6ec-4ddf-a5ff-a37241bb9b85.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/9571e8d1-e6ec-4ddf-a5ff-a37241bb9b85/9571e8d1-e6ec-4ddf-a5ff-a37241bb9b85.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/9571e8d1-e6ec-4ddf-a5ff-a37241bb9b85/9571e8d1-e6ec-4ddf-a5ff-a37241bb9b85.vtt" type="text/vtt" language="en"/><podcast:txt purpose="ai-content">true</podcast:txt><itunes:author>Beta Finch</itunes:author><itunes:subtitle>Stay tuned for AI-powered earnings analysis from Beta Finch.</itunes:subtitle><itunes:summary><![CDATA[Stay tuned for AI-powered earnings analysis from Beta Finch.<br /><br />This episode includes AI-generated content.]]></itunes:summary><itunes:duration>121</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/b5d47710cff47d2633c270bf330bc928.jpg"/><itunes:episodeType>full</itunes:episodeType></item></channel></rss>
