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<rss xmlns:itunes="http://www.itunes.com/dtds/podcast-1.0.dtd" xmlns:atom="http://www.w3.org/2005/Atom" xmlns:podcast="https://podcastindex.org/namespace/1.0" xmlns:media="http://search.yahoo.com/mrss/" version="2.0"><channel><title>RadOnc Smart Review</title><link>https://www.spreaker.com/podcast/radonc-smart-review--6594670</link><description><![CDATA[AI Generated Podcast reviewing various topics in Radiation Oncology for Residents on the go.]]></description><atom:link href="https://www.spreaker.com/show/6594670/episodes/feed" rel="self" type="application/rss+xml"/><language>en</language><category>Education</category><copyright>Copyright radoncsmartlearn</copyright><image><url>https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg</url><title>RadOnc Smart Review</title><link>https://www.spreaker.com/podcast/radonc-smart-review--6594670</link></image><lastBuildDate>Sat, 29 Aug 2026 23:23:34 +0000</lastBuildDate><itunes:author>Abass Conteh</itunes:author><itunes:owner><itunes:name>radoncsmartlearn</itunes:name><itunes:email>support@radoncsmartlearn.com</itunes:email></itunes:owner><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:subtitle>AI Generated Podcast reviewing various topics in Radiation Oncology for Residents on the go.</itunes:subtitle><itunes:summary><![CDATA[AI Generated Podcast reviewing various topics in Radiation Oncology for Residents on the go.]]></itunes:summary><itunes:category text="Education"/><itunes:category text="Health &amp; Fitness"><itunes:category text="Medicine"/></itunes:category><itunes:explicit>false</itunes:explicit><podcast:guid>576d8359-08d3-5459-bf4a-e471e2b6a5a2</podcast:guid><itunes:type>episodic</itunes:type><item><title>G.I. E03:Resectable Esophageal and GEJ Cancer: CROSS, FLOT, and Perioperative Selection.</title><link>https://www.spreaker.com/episode/g-i-e03-resectable-esophageal-and-gej-cancer-cross-flot-and-perioperative-selection--74750485</link><description><![CDATA[Episode 3: Resectable Esophageal and GEJ Cancer: CROSS, FLOT, and Perioperative Selection. The modern approach to resectable esophageal cancer has evolved beyond simply asking if a patient needs preoperative treatment; for most locally advanced cancers, the answer is yes. In this episode, we dive into the more complex decision-making process: determining which preoperative strategy such as the CROSS or FLOT regimens best aligns with a patient's specific histology, tumor anatomy, risk profile, and surgical plan.]]></description><guid isPermaLink="false">ffb1bc70-05c4-4cd8-bc90-ffc9dc2ae765</guid><pubDate>Sat, 29 Aug 2026 21:45:02 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/74750485/4dad245b_c249_81fe_01f9_08ef6a4ee654.mp3" length="24387961" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2iqQtkeNANAPuZhQAsn6JG/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Episode 3: Resectable Esophageal and GEJ Cancer: CROSS, FLOT, and Perioperative Selection. The modern approach to resectable esophageal cancer has evolved beyond simply asking if a patient needs preoperative treatment; for most locally advanced...</itunes:subtitle><itunes:summary><![CDATA[Episode 3: Resectable Esophageal and GEJ Cancer: CROSS, FLOT, and Perioperative Selection. The modern approach to resectable esophageal cancer has evolved beyond simply asking if a patient needs preoperative treatment; for most locally advanced cancers, the answer is yes. In this episode, we dive into the more complex decision-making process: determining which preoperative strategy such as the CROSS or FLOT regimens best aligns with a patient's specific histology, tumor anatomy, risk profile, and surgical plan.]]></itunes:summary><itunes:duration>1525</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E02: Esophageal and GEJ Cancer Anatomy, Workup, Staging, and Surgery.</title><link>https://www.spreaker.com/episode/g-i-e02-esophageal-and-gej-cancer-anatomy-workup-staging-and-surgery--74750484</link><description><![CDATA[Episode 2: Esophageal and GEJ Cancer Anatomy, Workup, Staging, and Surgery. In this episode, we explore how esophageal cancer punishes imprecise anatomy. We discuss why a difference of just a few centimeters can fundamentally alter the primary site, staging schema, regional nodal map, operative approach, and the necessity for specialized airway or peritoneal staging procedures.]]></description><guid isPermaLink="false">93018102-1484-4b6b-b557-c55997a88d3d</guid><pubDate>Sat, 29 Aug 2026 21:08:21 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/74750484/596cb2ac_3083_6296_7800_b368cc8c5684.mp3" length="22610798" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5J8wW7PuWbcLvQ9ufdWbqE/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Episode 2: Esophageal and GEJ Cancer Anatomy, Workup, Staging, and Surgery. In this episode, we explore how esophageal cancer punishes imprecise anatomy. We discuss why a difference of just a few centimeters can fundamentally alter the primary site,...</itunes:subtitle><itunes:summary><![CDATA[Episode 2: Esophageal and GEJ Cancer Anatomy, Workup, Staging, and Surgery. In this episode, we explore how esophageal cancer punishes imprecise anatomy. We discuss why a difference of just a few centimeters can fundamentally alter the primary site, staging schema, regional nodal map, operative approach, and the necessity for specialized airway or peritoneal staging procedures.]]></itunes:summary><itunes:duration>1414</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E01: Foundations, Workup, Intent, Planning Safety, and Cross Cutting Toxicity</title><link>https://www.spreaker.com/episode/g-i-e01-foundations-workup-intent-planning-safety-and-cross-cutting-toxicity--74618194</link><description><![CDATA[This is Episode one: G I Oncology Foundations, Workup, Intent, Planning Safety, and Cross Cutting Toxicity.The most dangerous G I oncology error is often not choosing the wrong dose. It is answering the dose question before proving the diagnosis, stage, treatment intent, and problem that radiation is supposed to solve.]]></description><guid isPermaLink="false">4bac0871-62be-416d-8c52-427c51fca02a</guid><pubDate>Mon, 24 Aug 2026 03:20:38 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/74618194/d1548129_b6af_0597_645e_f4360a975bdd.mp3" length="20619641" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/134b76a6-39a5-4df2-92b2-904a5fb535ae/134b76a6-39a5-4df2-92b2-904a5fb535ae.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/134b76a6-39a5-4df2-92b2-904a5fb535ae/134b76a6-39a5-4df2-92b2-904a5fb535ae.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/134b76a6-39a5-4df2-92b2-904a5fb535ae/134b76a6-39a5-4df2-92b2-904a5fb535ae.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode one: G I Oncology Foundations, Workup, Intent, Planning Safety, and Cross Cutting Toxicity.The most dangerous G I oncology error is often not choosing the wrong dose. It is answering the dose question before proving the diagnosis,...</itunes:subtitle><itunes:summary><![CDATA[This is Episode one: G I Oncology Foundations, Workup, Intent, Planning Safety, and Cross Cutting Toxicity.The most dangerous G I oncology error is often not choosing the wrong dose. It is answering the dose question before proving the diagnosis, stage, treatment intent, and problem that radiation is supposed to solve.]]></itunes:summary><itunes:duration>1289</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E30: Comprehensive Thoracic Mock Oral Review</title><link>https://www.spreaker.com/episode/thoracic-e30-comprehensive-thoracic-mock-oral-review--73368267</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 30 is the comprehensive Thoracic mock oral. Three case blocks cover metastatic disease with consolidation versus oligoprogression, superior vena cava syndrome and thymic carcinoma, and a post-treatment pulmonary syndrome followed by thoracic reirradiation decisions. Each case includes a contrasting twist that changes the recommendation.<br />Pause before every model answer. Lead with the diagnosis or differential, known extent, and immediate problem; state intent before technique; name the management-changing unknown; and carry the plan through sequencing, radiation details, toxicity, surveillance, salvage, and the point at which the treatment goal must change.]]></description><guid isPermaLink="false">49c968d5-ce2c-4f1a-ab5a-9284f923f82f</guid><pubDate>Mon, 03 Aug 2026 03:31:21 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73368267/d58b0080_54e2_41f2_2c9b_b012462a75b3.mp3" length="33335725" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/59e2dfd2-012b-49ce-aaf0-0567f1fd34ab/59e2dfd2-012b-49ce-aaf0-0567f1fd34ab.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/59e2dfd2-012b-49ce-aaf0-0567f1fd34ab/59e2dfd2-012b-49ce-aaf0-0567f1fd34ab.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/59e2dfd2-012b-49ce-aaf0-0567f1fd34ab/59e2dfd2-012b-49ce-aaf0-0567f1fd34ab.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 30 is the comprehensive Thoracic mock oral. Three case blocks cover metastatic disease with consolidation versus oligoprogression, superior vena cava syndrome and thymic...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 30 is the comprehensive Thoracic mock oral. Three case blocks cover metastatic disease with consolidation versus oligoprogression, superior vena cava syndrome and thymic carcinoma, and a post-treatment pulmonary syndrome followed by thoracic reirradiation decisions. Each case includes a contrasting twist that changes the recommendation.<br />Pause before every model answer. Lead with the diagnosis or differential, known extent, and immediate problem; state intent before technique; name the management-changing unknown; and carry the plan through sequencing, radiation details, toxicity, surveillance, salvage, and the point at which the treatment goal must change.]]></itunes:summary><itunes:duration>2084</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>30</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E29: Thoracic Oncology Board Synthesis</title><link>https://www.spreaker.com/episode/thoracic-e29-thoracic-oncology-board-synthesis--73368272</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 29 is a board-synthesis workshop built around the order of operations that keeps thoracic decisions safe. We move from diagnosis and stage uncertainty to management-changing workup, invasive staging, operability, resectability, treatment intent, multimodality sequence, radiation indication, planning priorities, toxicity, surveillance, and salvage.<br />The disease-specific path changes across non-small cell lung cancer, small cell lung cancer, thymic tumors, mesothelioma, metastatic disease, palliation, toxicity, and reirradiation—but the decision discipline should remain portable.]]></description><guid isPermaLink="false">61574c32-2894-4f41-aac9-c6e00895905c</guid><pubDate>Mon, 03 Aug 2026 03:30:30 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73368272/1ec760af_76ee_57d0_b668_cef5003d877e.mp3" length="40008861" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/6087ca6d-8a7d-4364-8594-cdaf585a54ed/6087ca6d-8a7d-4364-8594-cdaf585a54ed.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/6087ca6d-8a7d-4364-8594-cdaf585a54ed/6087ca6d-8a7d-4364-8594-cdaf585a54ed.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/6087ca6d-8a7d-4364-8594-cdaf585a54ed/6087ca6d-8a7d-4364-8594-cdaf585a54ed.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 29 is a board-synthesis workshop built around the order of operations that keeps thoracic decisions safe. We move from diagnosis and stage uncertainty to management-changing...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 29 is a board-synthesis workshop built around the order of operations that keeps thoracic decisions safe. We move from diagnosis and stage uncertainty to management-changing workup, invasive staging, operability, resectability, treatment intent, multimodality sequence, radiation indication, planning priorities, toxicity, surveillance, and salvage.<br />The disease-specific path changes across non-small cell lung cancer, small cell lung cancer, thymic tumors, mesothelioma, metastatic disease, palliation, toxicity, and reirradiation—but the decision discipline should remain portable.]]></itunes:summary><itunes:duration>2501</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>29</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E28: Thoracic Reirradiation and Cumulative Dose</title><link>https://www.spreaker.com/episode/thoracic-e28-thoracic-reirradiation-and-cumulative-dose--73368277</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 28 approaches thoracic reirradiation as a new treatment decision made in the shadow of a prior course. Before discussing dose, we define intent, alternatives, expected benefit, prior-plan reconstruction, registration uncertainty, cumulative exposure, and the organ that could turn an elegant plan into a catastrophic event.<br />The episode provides a framework for balancing meaningful local control against potentially irreversible or fatal toxicity, communicating uncertainty honestly, and recognizing when cumulative central-organ risk makes another strategy safer.]]></description><guid isPermaLink="false">d1b9fe1a-5001-4d13-8db4-f3b1f8bedc1e</guid><pubDate>Mon, 03 Aug 2026 03:29:36 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73368277/3f7a3290_51f7_a8ae_3da7_9102657afe2d.mp3" length="43767568" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/f00f1912-3b67-4899-9560-8f0cf6c5bc48/f00f1912-3b67-4899-9560-8f0cf6c5bc48.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/f00f1912-3b67-4899-9560-8f0cf6c5bc48/f00f1912-3b67-4899-9560-8f0cf6c5bc48.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/f00f1912-3b67-4899-9560-8f0cf6c5bc48/f00f1912-3b67-4899-9560-8f0cf6c5bc48.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 28 approaches thoracic reirradiation as a new treatment decision made in the shadow of a prior course. Before discussing dose, we define intent, alternatives, expected benefit,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 28 approaches thoracic reirradiation as a new treatment decision made in the shadow of a prior course. Before discussing dose, we define intent, alternatives, expected benefit, prior-plan reconstruction, registration uncertainty, cumulative exposure, and the organ that could turn an elegant plan into a catastrophic event.<br />The episode provides a framework for balancing meaningful local control against potentially irreversible or fatal toxicity, communicating uncertainty honestly, and recognizing when cumulative central-organ risk makes another strategy safer.]]></itunes:summary><itunes:duration>2736</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>28</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E27: Thoracic Toxicity: Prevention, Recognition, and Differential Diagnosis</title><link>https://www.spreaker.com/episode/thoracic-e27-thoracic-toxicity-prevention-recognition-and-differential-diagnosis--73368286</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 27 tackles thoracic toxicity as a differential-diagnosis problem. Cough, dyspnea, dysphagia, fever, fatigue, chest discomfort, and palpitations may reflect radiation injury, infection, recurrent cancer, airway obstruction, cardiac disease, dehydration, systemic therapy, or more than one process at once.<br />Using a post-chemoradiation patient with evolving pulmonary and swallowing symptoms, we practice stability assessment, severity grading, treatment reconstruction, comparison with delivered dose, testing of dangerous alternatives, interruption and escalation decisions, and documentation of uncertainty with a clear reassessment endpoint.]]></description><guid isPermaLink="false">71042038-4e4a-4cf7-a7e3-21bf44bf91d3</guid><pubDate>Mon, 03 Aug 2026 03:28:27 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73368286/1b4cb2b5_2b0f_ba8b_c6f8_aec042c8ceec.mp3" length="34963676" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/976bd9ed-0b1a-4890-9e2a-dc6a84ece920/976bd9ed-0b1a-4890-9e2a-dc6a84ece920.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/976bd9ed-0b1a-4890-9e2a-dc6a84ece920/976bd9ed-0b1a-4890-9e2a-dc6a84ece920.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/976bd9ed-0b1a-4890-9e2a-dc6a84ece920/976bd9ed-0b1a-4890-9e2a-dc6a84ece920.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 27 tackles thoracic toxicity as a differential-diagnosis problem. Cough, dyspnea, dysphagia, fever, fatigue, chest discomfort, and palpitations may reflect radiation injury,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 27 tackles thoracic toxicity as a differential-diagnosis problem. Cough, dyspnea, dysphagia, fever, fatigue, chest discomfort, and palpitations may reflect radiation injury, infection, recurrent cancer, airway obstruction, cardiac disease, dehydration, systemic therapy, or more than one process at once.<br />Using a post-chemoradiation patient with evolving pulmonary and swallowing symptoms, we practice stability assessment, severity grading, treatment reconstruction, comparison with delivered dose, testing of dangerous alternatives, interruption and escalation decisions, and documentation of uncertainty with a clear reassessment endpoint.]]></itunes:summary><itunes:duration>2186</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>27</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E26: Pleural Mesothelioma</title><link>https://www.spreaker.com/episode/thoracic-e26-pleural-mesothelioma--73368273</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 26 treats pleural mesothelioma as the surface-spreading disease it is—not as a spherical lung mass. We cover diagnostic adequacy, histology, anatomic extent, operability, and whether meaningful cytoreduction is achievable before turning to the radiation problem.<br />Planning then branches by operation. After lung-sparing pleurectomy and decortication, two lungs remain around a large concave pleural target; after extrapleural pneumonectomy, one lung remains and even a modest low-dose bath can be dangerous. The recommendation must begin with the actual operation and expected pulmonary risk.]]></description><guid isPermaLink="false">560a7518-183e-4114-8a6d-340ffeee3b51</guid><pubDate>Mon, 03 Aug 2026 03:27:31 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73368273/43edd536_3d89_b536_2dc5_0561ede2bbbd.mp3" length="41182073" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/d908a7a7-ded9-4e19-a330-a1eef74790fa/d908a7a7-ded9-4e19-a330-a1eef74790fa.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/d908a7a7-ded9-4e19-a330-a1eef74790fa/d908a7a7-ded9-4e19-a330-a1eef74790fa.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/d908a7a7-ded9-4e19-a330-a1eef74790fa/d908a7a7-ded9-4e19-a330-a1eef74790fa.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 26 treats pleural mesothelioma as the surface-spreading disease it is—not as a spherical lung mass. We cover diagnostic adequacy, histology, anatomic extent, operability, and...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 26 treats pleural mesothelioma as the surface-spreading disease it is—not as a spherical lung mass. We cover diagnostic adequacy, histology, anatomic extent, operability, and whether meaningful cytoreduction is achievable before turning to the radiation problem.<br />Planning then branches by operation. After lung-sparing pleurectomy and decortication, two lungs remain around a large concave pleural target; after extrapleural pneumonectomy, one lung remains and even a modest low-dose bath can be dangerous. The recommendation must begin with the actual operation and expected pulmonary risk.]]></itunes:summary><itunes:duration>2574</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>26</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E25: Thymic Malignancies and Selected Rare Thoracic Tumors</title><link>https://www.spreaker.com/episode/thoracic-e25-thymic-malignancies-and-selected-rare-thoracic-tumors--73368278</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 25 uses thymic malignancies to build a disciplined approach to rare thoracic tumors. We address diagnostic pathways, myasthenic symptoms, biopsy-route hazards, the difference between operability and an R0 resection, true invasion versus simple contact, postoperative radiation selection, and reconstruction of the tumor bed.<br />The larger lesson is how to reason when evidence is sparse: avoid automatic extrapolation from common lung cancer, state uncertainty honestly, and build a recommendation from anatomy, pathology, surgical findings, recurrence risk, and achievable treatment geometry.]]></description><guid isPermaLink="false">9f75adc3-315a-4cf2-b99e-0087448e6a74</guid><pubDate>Mon, 03 Aug 2026 03:26:36 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73368278/67320bf5_3cc2_ba6f_ae09_f33f3bd3b7d9.mp3" length="35397100" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/2bb171a2-e25e-48eb-9244-98ae49ac9b68/2bb171a2-e25e-48eb-9244-98ae49ac9b68.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/2bb171a2-e25e-48eb-9244-98ae49ac9b68/2bb171a2-e25e-48eb-9244-98ae49ac9b68.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/2bb171a2-e25e-48eb-9244-98ae49ac9b68/2bb171a2-e25e-48eb-9244-98ae49ac9b68.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 25 uses thymic malignancies to build a disciplined approach to rare thoracic tumors. We address diagnostic pathways, myasthenic symptoms, biopsy-route hazards, the difference...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 25 uses thymic malignancies to build a disciplined approach to rare thoracic tumors. We address diagnostic pathways, myasthenic symptoms, biopsy-route hazards, the difference between operability and an R0 resection, true invasion versus simple contact, postoperative radiation selection, and reconstruction of the tumor bed.<br />The larger lesson is how to reason when evidence is sparse: avoid automatic extrapolation from common lung cancer, state uncertainty honestly, and build a recommendation from anatomy, pathology, surgical findings, recurrence risk, and achievable treatment geometry.]]></itunes:summary><itunes:duration>2213</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>25</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E24: Thoracic Palliation and Oncologic Emergencies</title><link>https://www.spreaker.com/episode/thoracic-e24-thoracic-palliation-and-oncologic-emergencies--73368284</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 24 brings structure to thoracic palliation and oncologic emergencies. We balance the danger of moving too slowly during airway, vascular, spinal-cord, pericardial, or respiratory compromise against the harm of giving empiric radiation to a stable patient before preserving diagnosis, stage, and the best procedural or systemic option.<br />The episode emphasizes stabilization first, then intervention matched to mechanism and time horizon. Radiation may be central, adjunctive, delayed until tissue is obtained, or unnecessary when another treatment is more direct.]]></description><guid isPermaLink="false">7255eff3-8eb9-4923-bcbc-f4e84819c310</guid><pubDate>Mon, 03 Aug 2026 03:25:47 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73368284/cfd9bffe_c912_554c_ed45_9cfff361b703.mp3" length="40260473" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/4cca171e-dc01-4203-9515-3e38092a2ff3/4cca171e-dc01-4203-9515-3e38092a2ff3.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/4cca171e-dc01-4203-9515-3e38092a2ff3/4cca171e-dc01-4203-9515-3e38092a2ff3.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/4cca171e-dc01-4203-9515-3e38092a2ff3/4cca171e-dc01-4203-9515-3e38092a2ff3.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 24 brings structure to thoracic palliation and oncologic emergencies. We balance the danger of moving too slowly during airway, vascular, spinal-cord, pericardial, or respiratory...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 24 brings structure to thoracic palliation and oncologic emergencies. We balance the danger of moving too slowly during airway, vascular, spinal-cord, pericardial, or respiratory compromise against the harm of giving empiric radiation to a stable patient before preserving diagnosis, stage, and the best procedural or systemic option.<br />The episode emphasizes stabilization first, then intervention matched to mechanism and time horizon. Radiation may be central, adjunctive, delayed until tissue is obtained, or unnecessary when another treatment is more direct.]]></itunes:summary><itunes:duration>2517</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>24</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E23: Oligometastatic and Oligoprogressive Non-Small-Cell Lung Cancer</title><link>https://www.spreaker.com/episode/thoracic-e23-oligometastatic-and-oligoprogressive-non-small-cell-lung-cancer--73366167</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 23 separates two often-confused strategies in limited metastatic non-small cell lung cancer: comprehensive treatment of every known site after systemic control and ablation of a resistant site during otherwise effective therapy. A lesion count alone is not a biological diagnosis or a treatment indication.<br />Using a thoracic primary with limited adrenal and bone disease as the anchor, we examine diagnostic confidence, systemic response, disease pace, technical feasibility, cumulative toxicity, and whether local therapy truly complements the systemic strategy rather than delaying recognition of widespread failure.]]></description><guid isPermaLink="false">d13a939e-50d2-4343-94f8-f6974791a514</guid><pubDate>Mon, 03 Aug 2026 03:21:26 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366167/f0c55bc6_34ee_0692_a3a8_517d6de4d069.mp3" length="35573897" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/64a77694-f998-47bd-8480-71093070ebe8/64a77694-f998-47bd-8480-71093070ebe8.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/64a77694-f998-47bd-8480-71093070ebe8/64a77694-f998-47bd-8480-71093070ebe8.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/64a77694-f998-47bd-8480-71093070ebe8/64a77694-f998-47bd-8480-71093070ebe8.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 23 separates two often-confused strategies in limited metastatic non-small cell lung cancer: comprehensive treatment of every known site after systemic control and ablation of a...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 23 separates two often-confused strategies in limited metastatic non-small cell lung cancer: comprehensive treatment of every known site after systemic control and ablation of a resistant site during otherwise effective therapy. A lesion count alone is not a biological diagnosis or a treatment indication.<br />Using a thoracic primary with limited adrenal and bone disease as the anchor, we examine diagnostic confidence, systemic response, disease pace, technical feasibility, cumulative toxicity, and whether local therapy truly complements the systemic strategy rather than delaying recognition of widespread failure.]]></itunes:summary><itunes:duration>2224</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>23</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E22: Metastatic Non-Small-Cell Lung Cancer and Radiation Therapy–Systemic Therapy Integration</title><link>https://www.spreaker.com/episode/thoracic-e22-metastatic-non-small-cell-lung-cancer-and-radiation-therapy-systemic-therapy-integration--73366166</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 22 focuses on integrating radiation and systemic therapy in metastatic non-small cell lung cancer without allowing two independent treatment calendars to collide. The durable skill is not memorizing one universal drug-hold table, but making a transparent risk decision for the exact agent, target, dose per fraction, organ exposure, urgency, and prior toxicity.<br />We also define ownership: who pauses treatment, what evidence is required to restart, and how to balance radiation benefit against the consequences of interrupting an effective systemic therapy.]]></description><guid isPermaLink="false">8c6ca9c6-a79c-49f5-9c00-53b46f3dee1b</guid><pubDate>Mon, 03 Aug 2026 03:20:27 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366166/f7647252_ea60_2b14_50dd_eb18cdf7b82a.mp3" length="29660610" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/8359f6a0-6f82-424e-9b97-5b618fb26b45/8359f6a0-6f82-424e-9b97-5b618fb26b45.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/8359f6a0-6f82-424e-9b97-5b618fb26b45/8359f6a0-6f82-424e-9b97-5b618fb26b45.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/8359f6a0-6f82-424e-9b97-5b618fb26b45/8359f6a0-6f82-424e-9b97-5b618fb26b45.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 22 focuses on integrating radiation and systemic therapy in metastatic non-small cell lung cancer without allowing two independent treatment calendars to collide. The durable...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 22 focuses on integrating radiation and systemic therapy in metastatic non-small cell lung cancer without allowing two independent treatment calendars to collide. The durable skill is not memorizing one universal drug-hold table, but making a transparent risk decision for the exact agent, target, dose per fraction, organ exposure, urgency, and prior toxicity.<br />We also define ownership: who pauses treatment, what evidence is required to restart, and how to balance radiation benefit against the consequences of interrupting an effective systemic therapy.]]></itunes:summary><itunes:duration>1854</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>22</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E21: Stage III Non-Small Cell Lung Cancer and Small Cell Lung Cancer Mock Oral</title><link>https://www.spreaker.com/episode/thoracic-e21-stage-iii-non-small-cell-lung-cancer-and-small-cell-lung-cancer-mock-oral--73366190</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 21 is a three-block mock oral covering fit unresectable stage III non-small cell lung cancer, frail unresectable stage III disease, and small cell lung cancer. The cases test concurrent versus modified chemoradiation, planning and toxicity management, post-treatment selection, brain-directed decisions, surveillance, and salvage.<br />Pause before each answer. Lead with diagnosis, stage framework, and intent; identify the stage-driving evidence; distinguish operability from resectability; then defend the treatment sequence, radiation plan, organ-at-risk tradeoffs, interruption strategy, and the finding that would change your recommendation.]]></description><guid isPermaLink="false">f8422489-6fe7-4690-a487-6f5bfe8c7548</guid><pubDate>Mon, 03 Aug 2026 03:19:30 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366190/f201407f_4289_ee0d_4ebe_6e6bb561d76d.mp3" length="41976195" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/a3407345-80d6-46d4-bc59-e2219a9a277b/a3407345-80d6-46d4-bc59-e2219a9a277b.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/a3407345-80d6-46d4-bc59-e2219a9a277b/a3407345-80d6-46d4-bc59-e2219a9a277b.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/a3407345-80d6-46d4-bc59-e2219a9a277b/a3407345-80d6-46d4-bc59-e2219a9a277b.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 21 is a three-block mock oral covering fit unresectable stage III non-small cell lung cancer, frail unresectable stage III disease, and small cell lung cancer. The cases test...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 21 is a three-block mock oral covering fit unresectable stage III non-small cell lung cancer, frail unresectable stage III disease, and small cell lung cancer. The cases test concurrent versus modified chemoradiation, planning and toxicity management, post-treatment selection, brain-directed decisions, surveillance, and salvage.<br />Pause before each answer. Lead with diagnosis, stage framework, and intent; identify the stage-driving evidence; distinguish operability from resectability; then defend the treatment sequence, radiation plan, organ-at-risk tradeoffs, interruption strategy, and the finding that would change your recommendation.]]></itunes:summary><itunes:duration>2624</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>21</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E20: Extensive-Stage Small Cell Lung Cancer and Thoracic Radiation</title><link>https://www.spreaker.com/episode/thoracic-e20-extensive-stage-small-cell-lung-cancer-and-thoracic-radiation--73366183</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 20 clarifies the selective role of thoracic radiation in extensive-stage small cell lung cancer. We distinguish consolidative treatment after a favorable systemic response from palliative treatment for symptoms or threatened thoracic function—two indications that may use the same machine but differ in intent, urgency, target, dose, and acceptable burden.<br />Using persistent thoracic disease after systemic therapy as the anchor, we weigh extracranial disease pace, functional trajectory, competing systemic risk, symptom risk, and whether a meaningful thoracic target can be treated safely.]]></description><guid isPermaLink="false">d68c5b4c-9459-43d1-890d-c0e29a214056</guid><pubDate>Mon, 03 Aug 2026 03:18:38 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366183/3a378c25_deb3_957f_79a0_ffb88353a990.mp3" length="31709446" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/85349354-00d5-493c-a4a4-10ce8aa27e1f/85349354-00d5-493c-a4a4-10ce8aa27e1f.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/85349354-00d5-493c-a4a4-10ce8aa27e1f/85349354-00d5-493c-a4a4-10ce8aa27e1f.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/85349354-00d5-493c-a4a4-10ce8aa27e1f/85349354-00d5-493c-a4a4-10ce8aa27e1f.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 20 clarifies the selective role of thoracic radiation in extensive-stage small cell lung cancer. We distinguish consolidative treatment after a favorable systemic response from...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 20 clarifies the selective role of thoracic radiation in extensive-stage small cell lung cancer. We distinguish consolidative treatment after a favorable systemic response from palliative treatment for symptoms or threatened thoracic function—two indications that may use the same machine but differ in intent, urgency, target, dose, and acceptable burden.<br />Using persistent thoracic disease after systemic therapy as the anchor, we weigh extracranial disease pace, functional trajectory, competing systemic risk, symptom risk, and whether a meaningful thoracic target can be treated safely.]]></itunes:summary><itunes:duration>1982</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>20</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E19: PCI, MRI Surveillance, and Hippocampal Avoidance</title><link>https://www.spreaker.com/episode/thoracic-e19-pci-mri-surveillance-and-hippocampal-avoidance--73366193</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 19 examines the decision between prophylactic cranial irradiation and structured MRI surveillance in small cell lung cancer, including the role of hippocampal avoidance. We place the evidence in its imaging and treatment era rather than treating older trials as if every patient had modern brain MRI and dependable salvage access.<br />The discussion centers on shared decision-making: intracranial-control benefit, disease extent and response, surveillance reliability, neurocognitive risk, functional priorities, and the practical consequences of choosing observation or cranial treatment.]]></description><guid isPermaLink="false">324a8c89-6a45-4d5d-95ef-d9b70f3c2e46</guid><pubDate>Mon, 03 Aug 2026 03:17:36 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366193/5e285f62_0c00_ca00_a495_b834a18de9f3.mp3" length="41604630" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/4ffa6f8e-4e30-4f61-b25d-1ffaf7dc622d/4ffa6f8e-4e30-4f61-b25d-1ffaf7dc622d.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/4ffa6f8e-4e30-4f61-b25d-1ffaf7dc622d/4ffa6f8e-4e30-4f61-b25d-1ffaf7dc622d.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/4ffa6f8e-4e30-4f61-b25d-1ffaf7dc622d/4ffa6f8e-4e30-4f61-b25d-1ffaf7dc622d.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 19 examines the decision between prophylactic cranial irradiation and structured MRI surveillance in small cell lung cancer, including the role of hippocampal avoidance. We place...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 19 examines the decision between prophylactic cranial irradiation and structured MRI surveillance in small cell lung cancer, including the role of hippocampal avoidance. We place the evidence in its imaging and treatment era rather than treating older trials as if every patient had modern brain MRI and dependable salvage access.<br />The discussion centers on shared decision-making: intracranial-control benefit, disease extent and response, surveillance reliability, neurocognitive risk, functional priorities, and the practical consequences of choosing observation or cranial treatment.]]></itunes:summary><itunes:duration>2601</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>19</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E18: Limited-Stage Small Cell Lung Cancer: Timing, Planning, and Consolidation</title><link>https://www.spreaker.com/episode/thoracic-e18-limited-stage-small-cell-lung-cancer-timing-planning-and-consolidation--73366182</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 18 follows limited-stage small cell lung cancer from the start of chemotherapy through thoracic radiation planning and post-treatment decisions. We discuss treatment timing, fractionation, target construction, the use of pre- and post-chemotherapy disease information, image guidance, and how toxicity or interruptions change the plan.<br />The episode keeps the sequence coherent: choose a curative strategy the patient can complete, avoid losing clinically meaningful disease in the planning process, and reassess response before decisions about consolidation and brain-directed management.]]></description><guid isPermaLink="false">c01cc29f-9b17-48ae-9e8c-40cf1cee54d0</guid><pubDate>Mon, 03 Aug 2026 03:16:30 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366182/8e9a86ab_3f39_c418_4249_bb4474a97ecb.mp3" length="41475480" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/015d3797-4b62-4959-9f0d-693689e093b3/015d3797-4b62-4959-9f0d-693689e093b3.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/015d3797-4b62-4959-9f0d-693689e093b3/015d3797-4b62-4959-9f0d-693689e093b3.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/015d3797-4b62-4959-9f0d-693689e093b3/015d3797-4b62-4959-9f0d-693689e093b3.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 18 follows limited-stage small cell lung cancer from the start of chemotherapy through thoracic radiation planning and post-treatment decisions. We discuss treatment timing,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 18 follows limited-stage small cell lung cancer from the start of chemotherapy through thoracic radiation planning and post-treatment decisions. We discuss treatment timing, fractionation, target construction, the use of pre- and post-chemotherapy disease information, image guidance, and how toxicity or interruptions change the plan.<br />The episode keeps the sequence coherent: choose a curative strategy the patient can complete, avoid losing clinically meaningful disease in the planning process, and reassess response before decisions about consolidation and brain-directed management.]]></itunes:summary><itunes:duration>2593</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E17: SCLC Foundations and Curative Treatment</title><link>https://www.spreaker.com/episode/thoracic-e17-sclc-foundations-and-curative-treatment--73366220</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 17 establishes the foundations of small cell lung cancer care: pathologic confirmation, complete staging, mandatory attention to brain imaging, the rare role of surgery, and entry into curative treatment for limited-stage disease.<br />We focus on the decisions that prevent stage and intent errors—distinguishing limited from extensive disease, identifying when invasive staging or additional workup matters, and coordinating chemotherapy with thoracic radiation. The goal is a concise, board-ready framework that remains accurate when the clinical presentation is incomplete.]]></description><guid isPermaLink="false">8c932bc6-6146-41c9-8d74-cb3d1259cb3d</guid><pubDate>Mon, 03 Aug 2026 03:15:25 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366220/f49ed38e_dd78_e508_95a2_890ca0fa7b5d.mp3" length="43120986" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/dfe247ec-3c50-42fd-8439-c880f595f295/dfe247ec-3c50-42fd-8439-c880f595f295.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/dfe247ec-3c50-42fd-8439-c880f595f295/dfe247ec-3c50-42fd-8439-c880f595f295.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/dfe247ec-3c50-42fd-8439-c880f595f295/dfe247ec-3c50-42fd-8439-c880f595f295.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 17 establishes the foundations of small cell lung cancer care: pathologic confirmation, complete staging, mandatory attention to brain imaging, the rare role of surgery, and...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 17 establishes the foundations of small cell lung cancer care: pathologic confirmation, complete staging, mandatory attention to brain imaging, the rare role of surgery, and entry into curative treatment for limited-stage disease.<br />We focus on the decisions that prevent stage and intent errors—distinguishing limited from extensive disease, identifying when invasive staging or additional workup matters, and coordinating chemotherapy with thoracic radiation. The goal is a concise, board-ready framework that remains accurate when the clinical presentation is incomplete.]]></itunes:summary><itunes:duration>2695</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E16: After Definitive CRT: Consolidation, Toxicity, and Relapse</title><link>https://www.spreaker.com/episode/thoracic-e16-after-definitive-crt-consolidation-toxicity-and-relapse--73366231</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 16 begins where definitive chemoradiation ends. We organize post-treatment care around three competing possibilities: eligibility for consolidation therapy, clinically important toxicity, and early relapse or progression.<br />The episode shows how to interpret symptoms and imaging without prematurely labeling every pulmonary change as radiation injury, how to stabilize and evaluate treatment-limiting toxicity, and how molecular findings, performance status, disease distribution, and prior therapy shape the next systemic or local treatment decision.]]></description><guid isPermaLink="false">1ac10293-97e2-4268-9101-3aac3b056942</guid><pubDate>Mon, 03 Aug 2026 03:14:13 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366231/780347d5_1b58_c78b_4554_cf88cd2a5630.mp3" length="42399170" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/0e3dd123-df0a-41cf-8407-50f115fec4e5/0e3dd123-df0a-41cf-8407-50f115fec4e5.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/0e3dd123-df0a-41cf-8407-50f115fec4e5/0e3dd123-df0a-41cf-8407-50f115fec4e5.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/0e3dd123-df0a-41cf-8407-50f115fec4e5/0e3dd123-df0a-41cf-8407-50f115fec4e5.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 16 begins where definitive chemoradiation ends. We organize post-treatment care around three competing possibilities: eligibility for consolidation therapy, clinically important...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 16 begins where definitive chemoradiation ends. We organize post-treatment care around three competing possibilities: eligibility for consolidation therapy, clinically important toxicity, and early relapse or progression.<br />The episode shows how to interpret symptoms and imaging without prematurely labeling every pulmonary change as radiation injury, how to stabilize and evaluate treatment-limiting toxicity, and how molecular findings, performance status, disease distribution, and prior therapy shape the next systemic or local treatment decision.]]></itunes:summary><itunes:duration>2650</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>16</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E15: Stage Three Targeting and Treatment Planning</title><link>https://www.spreaker.com/episode/thoracic-e15-stage-three-targeting-and-treatment-planning--73366216</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 15 is a planning-focused guide to definitive radiation for stage III non-small cell lung cancer. We move from simulation and motion assessment to gross disease, nodal volumes, target margins, technique, image guidance, adaptive triggers, and plan appraisal.<br />The core challenge is not simply achieving coverage. It is building a defensible plan that reflects the actual disease map while controlling heart, lung, esophageal, spinal-cord, and treatment-time risks. We also discuss when anatomy or response has changed enough that the original plan should no longer be treated as valid.]]></description><guid isPermaLink="false">63a3f914-1715-4f1f-bc49-d87489b7fff4</guid><pubDate>Mon, 03 Aug 2026 03:13:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366216/41f62a24_dd5e_dfad_f1fa_9980cb185206.mp3" length="36672711" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/f1d4fa73-4d2d-4217-a96d-490b2637dcfd/f1d4fa73-4d2d-4217-a96d-490b2637dcfd.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/f1d4fa73-4d2d-4217-a96d-490b2637dcfd/f1d4fa73-4d2d-4217-a96d-490b2637dcfd.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/f1d4fa73-4d2d-4217-a96d-490b2637dcfd/f1d4fa73-4d2d-4217-a96d-490b2637dcfd.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 15 is a planning-focused guide to definitive radiation for stage III non-small cell lung cancer. We move from simulation and motion assessment to gross disease, nodal volumes,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 15 is a planning-focused guide to definitive radiation for stage III non-small cell lung cancer. We move from simulation and motion assessment to gross disease, nodal volumes, target margins, technique, image guidance, adaptive triggers, and plan appraisal.<br />The core challenge is not simply achieving coverage. It is building a defensible plan that reflects the actual disease map while controlling heart, lung, esophageal, spinal-cord, and treatment-time risks. We also discuss when anatomy or response has changed enough that the original plan should no longer be treated as valid.]]></itunes:summary><itunes:duration>2292</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E14: Definitive Stage Three Management</title><link>https://www.spreaker.com/episode/thoracic-e14-definitive-stage-three-management--73366172</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 14 builds the definitive treatment framework for unresectable stage III non-small cell lung cancer. We begin by confirming a curable nonsurgical disease state, completing stage-defining workup, and deciding whether the patient can safely complete concurrent chemoradiation or needs a modified sequence.<br />From there, we connect treatment intensity to radiation dose, systemic therapy, interruption management, post-chemoradiation consolidation, surveillance, and relapse. The emphasis is on preserving curative intent when appropriate while making frailty, toxicity, progression, and molecular findings explicit decision points.]]></description><guid isPermaLink="false">617a196d-e34a-422e-ac33-dd8fcc8d6e64</guid><pubDate>Mon, 03 Aug 2026 03:11:47 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366172/be848c5c_fa2d_efc2_c22f_762b142de3da.mp3" length="43001449" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/981bef66-b594-46ff-8d64-2489f2a6e3ad/981bef66-b594-46ff-8d64-2489f2a6e3ad.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/981bef66-b594-46ff-8d64-2489f2a6e3ad/981bef66-b594-46ff-8d64-2489f2a6e3ad.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/981bef66-b594-46ff-8d64-2489f2a6e3ad/981bef66-b594-46ff-8d64-2489f2a6e3ad.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 14 builds the definitive treatment framework for unresectable stage III non-small cell lung cancer. We begin by confirming a curable nonsurgical disease state, completing...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 14 builds the definitive treatment framework for unresectable stage III non-small cell lung cancer. We begin by confirming a curable nonsurgical disease state, completing stage-defining workup, and deciding whether the patient can safely complete concurrent chemoradiation or needs a modified sequence.<br />From there, we connect treatment intensity to radiation dose, systemic therapy, interruption management, post-chemoradiation consolidation, surveillance, and relapse. The emphasis is on preserving curative intent when appropriate while making frailty, toxicity, progression, and molecular findings explicit decision points.]]></itunes:summary><itunes:duration>2688</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>14</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E13: Localized and Resectable Non-Small Cell Lung Cancer Mock Oral</title><link>https://www.spreaker.com/episode/thoracic-e13-localized-and-resectable-non-small-cell-lung-cancer-mock-oral--73366171</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 13 is a three-block mock oral in localized and resectable non-small cell lung cancer. The cases move from surgery versus stereotactic radiation for peripheral disease, to central and ultracentral anatomy, and then to resectable nodal and superior sulcus disease with multimodality sequencing and postoperative decisions.<br />Pause before each model answer and give a structured response: state the diagnosis and known extent, name the management-changing unknown, separate operability from resectability, declare treatment intent, and carry the recommendation through evidence, planning, safety, surveillance, and salvage.]]></description><guid isPermaLink="false">2b016b3e-8bef-4b41-ad98-d24027c31121</guid><pubDate>Mon, 03 Aug 2026 03:10:32 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366171/c29a1e35_de07_6b92_8415_f977e07631fc.mp3" length="39227696" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/38c56deb-9d73-4cd8-bbd6-80eceb86daf9/38c56deb-9d73-4cd8-bbd6-80eceb86daf9.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/38c56deb-9d73-4cd8-bbd6-80eceb86daf9/38c56deb-9d73-4cd8-bbd6-80eceb86daf9.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/38c56deb-9d73-4cd8-bbd6-80eceb86daf9/38c56deb-9d73-4cd8-bbd6-80eceb86daf9.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 13 is a three-block mock oral in localized and resectable non-small cell lung cancer. The cases move from surgery versus stereotactic radiation for peripheral disease, to central...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 13 is a three-block mock oral in localized and resectable non-small cell lung cancer. The cases move from surgery versus stereotactic radiation for peripheral disease, to central and ultracentral anatomy, and then to resectable nodal and superior sulcus disease with multimodality sequencing and postoperative decisions.<br />Pause before each model answer and give a structured response: state the diagnosis and known extent, name the management-changing unknown, separate operability from resectability, declare treatment intent, and carry the recommendation through evidence, planning, safety, surveillance, and salvage.]]></itunes:summary><itunes:duration>2452</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E12: PORT: Evidence, Selection, and Planning</title><link>https://www.spreaker.com/episode/thoracic-e12-port-evidence-selection-and-planning--73366236</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 12 takes a selective, evidence-based approach to postoperative radiation therapy for non-small cell lung cancer. We reconstruct residual disease, margin status, nodal burden and geography, surgical quality, the preoperative disease map, competing systemic risk, cardiopulmonary reserve, and the target that would actually be treated.<br />The episode explains why improved mediastinal control after complete resection does not automatically translate into a survival benefit, and how to weigh that local-control gain against heart, remaining-lung, esophageal, and spinal-cord exposure.]]></description><guid isPermaLink="false">a5237633-eb54-4f13-adae-138e73e8095e</guid><pubDate>Mon, 03 Aug 2026 03:09:41 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366236/066a011f_12f6_8276_967a_282bd936896a.mp3" length="42182249" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/b34d1194-7eed-4e5a-841e-c34866c92319/b34d1194-7eed-4e5a-841e-c34866c92319.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/b34d1194-7eed-4e5a-841e-c34866c92319/b34d1194-7eed-4e5a-841e-c34866c92319.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/b34d1194-7eed-4e5a-841e-c34866c92319/b34d1194-7eed-4e5a-841e-c34866c92319.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 12 takes a selective, evidence-based approach to postoperative radiation therapy for non-small cell lung cancer. We reconstruct residual disease, margin status, nodal burden and...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 12 takes a selective, evidence-based approach to postoperative radiation therapy for non-small cell lung cancer. We reconstruct residual disease, margin status, nodal burden and geography, surgical quality, the preoperative disease map, competing systemic risk, cardiopulmonary reserve, and the target that would actually be treated.<br />The episode explains why improved mediastinal control after complete resection does not automatically translate into a survival benefit, and how to weigh that local-control gain against heart, remaining-lung, esophageal, and spinal-cord exposure.]]></itunes:summary><itunes:duration>2637</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>12</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E11: Trimodality Therapy and Superior Sulcus Tumors</title><link>https://www.spreaker.com/episode/thoracic-e11-trimodality-therapy-and-superior-sulcus-tumors--73366176</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 11 examines trimodality therapy through the demanding example of a superior sulcus tumor. Before chemotherapy and radiation begin, the team must define thoracic-inlet invasion, nodal status, the feasibility of a margin-negative operation, the patient’s ability to tolerate that operation, and what the definitive fallback will be if surgery is cancelled.<br />We connect multidisciplinary selection to simulation, target design, organ-at-risk priorities, surgical timing, and continuity of curative treatment—so the sequence is a planned oncologic strategy rather than three disconnected modalities.]]></description><guid isPermaLink="false">ea7f8402-e3f8-446c-9b29-e7103427f50b</guid><pubDate>Mon, 03 Aug 2026 03:08:50 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366176/fd7ed965_6c37_9c47_5ab5_777a671edf50.mp3" length="31594925" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/b64e90ff-da5b-49b9-91af-1e23d09635f6/b64e90ff-da5b-49b9-91af-1e23d09635f6.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/b64e90ff-da5b-49b9-91af-1e23d09635f6/b64e90ff-da5b-49b9-91af-1e23d09635f6.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/b64e90ff-da5b-49b9-91af-1e23d09635f6/b64e90ff-da5b-49b9-91af-1e23d09635f6.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 11 examines trimodality therapy through the demanding example of a superior sulcus tumor. Before chemotherapy and radiation begin, the team must define thoracic-inlet invasion,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 11 examines trimodality therapy through the demanding example of a superior sulcus tumor. Before chemotherapy and radiation begin, the team must define thoracic-inlet invasion, nodal status, the feasibility of a margin-negative operation, the patient’s ability to tolerate that operation, and what the definitive fallback will be if surgery is cancelled.<br />We connect multidisciplinary selection to simulation, target design, organ-at-risk priorities, surgical timing, and continuity of curative treatment—so the sequence is a planned oncologic strategy rather than three disconnected modalities.]]></itunes:summary><itunes:duration>1975</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>11</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E10: Resectable Stage II Through III Non-Small Cell Lung Cancer</title><link>https://www.spreaker.com/episode/thoracic-e10-resectable-stage-ii-through-iii-non-small-cell-lung-cancer--73366177</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 10 builds a coherent curative strategy for resectable stage II through III non-small cell lung cancer. We show why a stage label alone cannot define medical operability, anatomic resectability, the required operation, the meaning of a PET-avid mediastinal node, or the best perioperative sequence.<br />The episode keeps radiation oncology engaged at the right moments: before a treatment path closes, when trimodality therapy is genuinely under consideration, and when response, margin status, residual nodal burden, or surgical findings reopen the local-risk calculation.]]></description><guid isPermaLink="false">09db83f8-f36f-4f69-8020-c5d3c676f390</guid><pubDate>Mon, 03 Aug 2026 03:08:06 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366177/1d7bd97e_4832_82ef_35d9_e656455f7023.mp3" length="38774210" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/d3782b7f-7d6d-43f2-b99c-3551ae25e6a5/d3782b7f-7d6d-43f2-b99c-3551ae25e6a5.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/d3782b7f-7d6d-43f2-b99c-3551ae25e6a5/d3782b7f-7d6d-43f2-b99c-3551ae25e6a5.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/d3782b7f-7d6d-43f2-b99c-3551ae25e6a5/d3782b7f-7d6d-43f2-b99c-3551ae25e6a5.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 10 builds a coherent curative strategy for resectable stage II through III non-small cell lung cancer. We show why a stage label alone cannot define medical operability, anatomic...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 10 builds a coherent curative strategy for resectable stage II through III non-small cell lung cancer. We show why a stage label alone cannot define medical operability, anatomic resectability, the required operation, the meaning of a PET-avid mediastinal node, or the best perioperative sequence.<br />The episode keeps radiation oncology engaged at the right moments: before a treatment path closes, when trimodality therapy is genuinely under consideration, and when response, margin status, residual nodal burden, or surgical findings reopen the local-risk calculation.]]></itunes:summary><itunes:duration>2424</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>10</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E09: Post-SBRT Imaging, Recurrence, and Salvage</title><link>https://www.spreaker.com/episode/thoracic-e09-post-sbrt-imaging-recurrence-and-salvage--73366204</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 9 addresses one of the hardest surveillance problems after lung stereotactic body radiation therapy: distinguishing expected evolving fibrosis and inflammation from true local recurrence. We integrate time from treatment, serial morphology, metabolic behavior, symptoms, physiology, original dose geometry, restaging, and the feasibility of biopsy.<br />The second half turns suspicion into a salvage decision. The goal is to preserve a potentially curative opportunity without treating benign post-treatment change or causing disproportionate injury to previously irradiated thoracic organs.]]></description><guid isPermaLink="false">757f0afb-e03b-473d-b687-534fd2831b3b</guid><pubDate>Mon, 03 Aug 2026 03:06:20 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366204/3e2a44ea_26f4_83a0_b9ea_c1b5c3a8d601.mp3" length="36673547" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/2cad9c79-8213-4bc0-98db-04f2aff8aab2/2cad9c79-8213-4bc0-98db-04f2aff8aab2.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/2cad9c79-8213-4bc0-98db-04f2aff8aab2/2cad9c79-8213-4bc0-98db-04f2aff8aab2.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/2cad9c79-8213-4bc0-98db-04f2aff8aab2/2cad9c79-8213-4bc0-98db-04f2aff8aab2.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 9 addresses one of the hardest surveillance problems after lung stereotactic body radiation therapy: distinguishing expected evolving fibrosis and inflammation from true local...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 9 addresses one of the hardest surveillance problems after lung stereotactic body radiation therapy: distinguishing expected evolving fibrosis and inflammation from true local recurrence. We integrate time from treatment, serial morphology, metabolic behavior, symptoms, physiology, original dose geometry, restaging, and the feasibility of biopsy.<br />The second half turns suspicion into a salvage decision. The goal is to preserve a potentially curative opportunity without treating benign post-treatment change or causing disproportionate injury to previously irradiated thoracic organs.]]></itunes:summary><itunes:duration>2293</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>9</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E08: High-Risk Early-Stage NSCLC: Central Tumors, Large Lesions, and ILD</title><link>https://www.spreaker.com/episode/thoracic-e08-high-risk-early-stage-nsclc-central-tumors-large-lesions-and-ild--73366219</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 8 explores the modifiers that can turn apparently early-stage non-small cell lung cancer into a high-risk radiation problem: central or ultracentral anatomy, endobronchial extension, large tumor size, and fibrotic interstitial lung disease. These features can change candidacy, fractionation, target priorities, image guidance, consent, and whether an ablative plan should be offered at all.<br />Rather than asking for a single central-lung dose, we ask which anatomic or patient-specific risk should control the recommendation and how to protect critical serial organs without pretending that every tradeoff can be solved by technique alone.]]></description><guid isPermaLink="false">c18c1cb7-7ba2-4918-b3f5-fb81f2d3e656</guid><pubDate>Mon, 03 Aug 2026 03:03:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366219/3e7eba77_e978_40d9_04f9_c66bf30dbe2e.mp3" length="36795591" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/772c9517-0774-4708-b61d-46fe0798cd82/772c9517-0774-4708-b61d-46fe0798cd82.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/772c9517-0774-4708-b61d-46fe0798cd82/772c9517-0774-4708-b61d-46fe0798cd82.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/772c9517-0774-4708-b61d-46fe0798cd82/772c9517-0774-4708-b61d-46fe0798cd82.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 8 explores the modifiers that can turn apparently early-stage non-small cell lung cancer into a high-risk radiation problem: central or ultracentral anatomy, endobronchial...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 8 explores the modifiers that can turn apparently early-stage non-small cell lung cancer into a high-risk radiation problem: central or ultracentral anatomy, endobronchial extension, large tumor size, and fibrotic interstitial lung disease. These features can change candidacy, fractionation, target priorities, image guidance, consent, and whether an ablative plan should be offered at all.<br />Rather than asking for a single central-lung dose, we ask which anatomic or patient-specific risk should control the recommendation and how to protect critical serial organs without pretending that every tradeoff can be solved by technique alone.]]></itunes:summary><itunes:duration>2300</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>8</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E07: Peripheral Lung SBRT</title><link>https://www.spreaker.com/episode/thoracic-e07-peripheral-lung-sbrt--73366187</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 7 is a practical workshop in peripheral lung stereotactic body radiation therapy. We move from candidacy and respiratory-motion data to target construction, fractionation, chest-wall risk, intermediate-dose falloff, image guidance, and the question that matters at every fraction: can the team reproduce the geometry that made the plan acceptable?<br />The episode emphasizes why a small target and short course do not make this simple treatment. A geometric miss, hidden serial organ, unreliable motion envelope, or weak setup strategy carries a large biological consequence when each fraction delivers an ablative dose.]]></description><guid isPermaLink="false">c5eaf8dd-2812-4d19-87a2-2abe7bfe2a20</guid><pubDate>Mon, 03 Aug 2026 03:03:30 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366187/fb3269a1_2e60_bd6d_76a3_3d895eab3a1e.mp3" length="38810990" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/4b72adf9-8471-4f44-8156-61985c268273/4b72adf9-8471-4f44-8156-61985c268273.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/4b72adf9-8471-4f44-8156-61985c268273/4b72adf9-8471-4f44-8156-61985c268273.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/4b72adf9-8471-4f44-8156-61985c268273/4b72adf9-8471-4f44-8156-61985c268273.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 7 is a practical workshop in peripheral lung stereotactic body radiation therapy. We move from candidacy and respiratory-motion data to target construction, fractionation,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 7 is a practical workshop in peripheral lung stereotactic body radiation therapy. We move from candidacy and respiratory-motion data to target construction, fractionation, chest-wall risk, intermediate-dose falloff, image guidance, and the question that matters at every fraction: can the team reproduce the geometry that made the plan acceptable?<br />The episode emphasizes why a small target and short course do not make this simple treatment. A geometric miss, hidden serial organ, unreliable motion envelope, or weak setup strategy carries a large biological consequence when each fraction delivers an ablative dose.]]></itunes:summary><itunes:duration>2426</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>7</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E06: Early-Stage Non-Small Cell Lung Cancer Treatment Selection</title><link>https://www.spreaker.com/episode/thoracic-e06-early-stage-non-small-cell-lung-cancer-treatment-selection--73366228</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 6 tackles early-stage non-small cell lung cancer as a treatment-selection problem, not a reflex comparison of surgery versus stereotactic body radiation therapy. We begin by confirming localized, node-negative disease, pursuing tissue when safely feasible, separating medical operability from anatomic resectability, and defining the actual operation and radiation course being compared.<br />Using a growing, FDG-avid peripheral lesion as the anchor, we make the diagnostic, functional, perioperative, and toxicity tradeoffs explicit so that the final recommendation remains conditional, multidisciplinary, and aligned with the patient’s informed goals.]]></description><guid isPermaLink="false">5c95a79a-861e-472f-bae2-69f63d6c40c3</guid><pubDate>Mon, 03 Aug 2026 03:02:43 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366228/0523e5fe_19df_4d5e_00d7_dff74131902e.mp3" length="41551549" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/d64a9a72-f574-42b2-a23d-4fe10fc7a55a/d64a9a72-f574-42b2-a23d-4fe10fc7a55a.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/d64a9a72-f574-42b2-a23d-4fe10fc7a55a/d64a9a72-f574-42b2-a23d-4fe10fc7a55a.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/d64a9a72-f574-42b2-a23d-4fe10fc7a55a/d64a9a72-f574-42b2-a23d-4fe10fc7a55a.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 6 tackles early-stage non-small cell lung cancer as a treatment-selection problem, not a reflex comparison of surgery versus stereotactic body radiation therapy. We begin by...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 6 tackles early-stage non-small cell lung cancer as a treatment-selection problem, not a reflex comparison of surgery versus stereotactic body radiation therapy. We begin by confirming localized, node-negative disease, pursuing tissue when safely feasible, separating medical operability from anatomic resectability, and defining the actual operation and radiation course being compared.<br />Using a growing, FDG-avid peripheral lesion as the anchor, we make the diagnostic, functional, perioperative, and toxicity tradeoffs explicit so that the final recommendation remains conditional, multidisciplinary, and aligned with the patient’s informed goals.]]></itunes:summary><itunes:duration>2597</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>6</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E05: Simulation, Respiratory Motion, and Image Guidance</title><link>https://www.spreaker.com/episode/thoracic-e05-simulation-respiratory-motion-and-image-guidance--73366195</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 5 moves thoracic radiation from the planning scan to the reality of treating a breathing patient. We examine how simulation, respiratory-motion assessment, treatment position, image registration, beam delivery, and image guidance must describe the same physical situation for the plan to remain trustworthy.<br />The episode provides a safety workflow for choosing a reproducible motion strategy, verifying the target or a justified surrogate, recognizing workflow failure, and escalating when treatment no longer behaves as designed. Throughout, we balance geometric confidence against treatment burden and complexity.]]></description><guid isPermaLink="false">760798f2-fb38-4a65-818d-5397d37dda89</guid><pubDate>Mon, 03 Aug 2026 03:00:52 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366195/a7b2f7a8_e216_707f_63dc_e89a0b66a79b.mp3" length="30570089" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/da448b91-7763-423a-971a-2e84346862df/da448b91-7763-423a-971a-2e84346862df.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/da448b91-7763-423a-971a-2e84346862df/da448b91-7763-423a-971a-2e84346862df.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/da448b91-7763-423a-971a-2e84346862df/da448b91-7763-423a-971a-2e84346862df.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 5 moves thoracic radiation from the planning scan to the reality of treating a breathing patient. We examine how simulation, respiratory-motion assessment, treatment position,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 5 moves thoracic radiation from the planning scan to the reality of treating a breathing patient. We examine how simulation, respiratory-motion assessment, treatment position, image registration, beam delivery, and image guidance must describe the same physical situation for the plan to remain trustworthy.<br />The episode provides a safety workflow for choosing a reproducible motion strategy, verifying the target or a justified surrogate, recognizing workflow failure, and escalating when treatment no longer behaves as designed. Throughout, we balance geometric confidence against treatment burden and complexity.]]></itunes:summary><itunes:duration>1911</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>5</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E04: Operability, Resectability, and Surgical Principles</title><link>https://www.spreaker.com/episode/thoracic-e04-operability-resectability-and-surgical-principles--73366197</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 4 separates three questions that are too often collapsed into the phrase surgical candidate: Can the patient tolerate the proposed operation? Can the cancer be completely removed by a reasonable operation? And even if both are possible, is surgery the right oncologic strategy for this patient?<br />We apply those distinctions to pulmonary reserve, cardiac risk, frailty, extent of resection, nodal disease, margin feasibility, and patient preference. The result is a clearer way to defend curative surgery, a nonsurgical local option, or a multimodality sequence without hiding the real limiting factor.]]></description><guid isPermaLink="false">ccc8f694-4f0a-4c4e-94f4-d7921679628e</guid><pubDate>Mon, 03 Aug 2026 03:00:21 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366197/1524c2fe_79f5_2f66_63e7_7dba7fc0dcd0.mp3" length="32917766" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/0f3d5d69-e7b1-45a2-b86c-a3d0c5b7ed78/0f3d5d69-e7b1-45a2-b86c-a3d0c5b7ed78.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/0f3d5d69-e7b1-45a2-b86c-a3d0c5b7ed78/0f3d5d69-e7b1-45a2-b86c-a3d0c5b7ed78.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/0f3d5d69-e7b1-45a2-b86c-a3d0c5b7ed78/0f3d5d69-e7b1-45a2-b86c-a3d0c5b7ed78.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 4 separates three questions that are too often collapsed into the phrase surgical candidate: Can the patient tolerate the proposed operation? Can the cancer be completely removed...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 4 separates three questions that are too often collapsed into the phrase surgical candidate: Can the patient tolerate the proposed operation? Can the cancer be completely removed by a reasonable operation? And even if both are possible, is surgery the right oncologic strategy for this patient?<br />We apply those distinctions to pulmonary reserve, cardiac risk, frailty, extent of resection, nodal disease, margin feasibility, and patient preference. The result is a clearer way to defend curative surgery, a nonsurgical local option, or a multimodality sequence without hiding the real limiting factor.]]></itunes:summary><itunes:duration>2058</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>4</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E03: Nodal Anatomy and Invasive Mediastinal Staging</title><link>https://www.spreaker.com/episode/thoracic-e03-nodal-anatomy-and-invasive-mediastinal-staging--73366212</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 3 connects thoracic nodal anatomy to the decisions it changes: imaging probability, procedural access, specimen adequacy, stage, and treatment intent. The goal is not simply to memorize station numbers, but to know whether a suspicious node was named correctly, could be reached by the chosen procedure, and was truly represented by an adequate sample.<br />We build a practical approach to invasive mediastinal staging that helps you explain what was sampled, what remains uncertain, and how the result should alter surgery, radiation, or multimodality treatment.]]></description><guid isPermaLink="false">2248524e-b4b7-408f-847d-1536e185d48d</guid><pubDate>Mon, 03 Aug 2026 02:59:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366212/cb367628_1a9f_024a_9cc4_f1c24ed86c69.mp3" length="43262674" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/5bbc816f-9f80-40fe-a1d3-48d8be3a0687/5bbc816f-9f80-40fe-a1d3-48d8be3a0687.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/5bbc816f-9f80-40fe-a1d3-48d8be3a0687/5bbc816f-9f80-40fe-a1d3-48d8be3a0687.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/5bbc816f-9f80-40fe-a1d3-48d8be3a0687/5bbc816f-9f80-40fe-a1d3-48d8be3a0687.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 3 connects thoracic nodal anatomy to the decisions it changes: imaging probability, procedural access, specimen adequacy, stage, and treatment intent. The goal is not simply to...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 3 connects thoracic nodal anatomy to the decisions it changes: imaging probability, procedural access, specimen adequacy, stage, and treatment intent. The goal is not simply to memorize station numbers, but to know whether a suspicious node was named correctly, could be reached by the chosen procedure, and was truly represented by an adequate sample.<br />We build a practical approach to invasive mediastinal staging that helps you explain what was sampled, what remains uncertain, and how the result should alter surgery, radiation, or multimodality treatment.]]></itunes:summary><itunes:duration>2704</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>3</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E02: Thoracic Imaging and TNM Staging</title><link>https://www.spreaker.com/episode/thoracic-e02-thoracic-imaging-and-tnm-staging--73366232</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 2 turns thoracic imaging and TNM staging into a clinical reasoning exercise rather than a table-lookup task. We work through how to integrate imperfect studies, separate radiographic suspicion from pathologic proof, and assign a transparent, version-correct anatomic stage without treating missing information as negative information.<br />The episode uses the American Joint Committee on Cancer Version 9 framework and emphasizes a repeatable sequence: confirm the diagnosis, assess whether imaging answers the staging questions, assign T, N, and M categories, translate the completed triplet, and clearly state any management-changing uncertainty.]]></description><guid isPermaLink="false">b8d0b9a0-52c7-4282-a7eb-5a8b831ee750</guid><pubDate>Mon, 03 Aug 2026 02:57:45 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366232/cccc30e5_e83c_a5f6_5cff_a1195d155f1e.mp3" length="40815523" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/a42fcada-6207-4839-af14-cb031837a860/a42fcada-6207-4839-af14-cb031837a860.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/a42fcada-6207-4839-af14-cb031837a860/a42fcada-6207-4839-af14-cb031837a860.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/a42fcada-6207-4839-af14-cb031837a860/a42fcada-6207-4839-af14-cb031837a860.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 2 turns thoracic imaging and TNM staging into a clinical reasoning exercise rather than a table-lookup task. We work through how to integrate imperfect studies, separate...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 2 turns thoracic imaging and TNM staging into a clinical reasoning exercise rather than a table-lookup task. We work through how to integrate imperfect studies, separate radiographic suspicion from pathologic proof, and assign a transparent, version-correct anatomic stage without treating missing information as negative information.<br />The episode uses the American Joint Committee on Cancer Version 9 framework and emphasizes a repeatable sequence: confirm the diagnosis, assess whether imaging answers the staging questions, assign T, N, and M categories, translate the completed triplet, and clearly state any management-changing uncertainty.]]></itunes:summary><itunes:duration>2551</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>2</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Thoracic E01: Screening, Pulmonary Nodules, and Tissue Diagnosis</title><link>https://www.spreaker.com/episode/thoracic-e01-screening-pulmonary-nodules-and-tissue-diagnosis--73366208</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 1 follows the clinical chain from lung-cancer screening and pulmonary-nodule evaluation to a tissue diagnosis that can actually guide treatment. We focus on the decisions that prevent downstream staging and planning errors: whether an abnormality belongs on a screening or diagnostic pathway, what to sample, how to judge tissue adequacy, and when additional workup will change management.<br />Use the episode to practice a board-ready four-question framework: define the likely diagnosis, establish the known disease extent, identify the uncertainty most likely to change management, and state the realistic treatment intent.]]></description><guid isPermaLink="false">1e29a025-4915-4263-af3e-ca19f0b0e60f</guid><pubDate>Mon, 03 Aug 2026 02:54:23 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73366208/09229094_0ce6_b30b_e9b1_c69e0692e88c.mp3" length="29902190" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/a3644f61-c6cd-4ceb-b3ea-4309c3131cfe/a3644f61-c6cd-4ceb-b3ea-4309c3131cfe.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/a3644f61-c6cd-4ceb-b3ea-4309c3131cfe/a3644f61-c6cd-4ceb-b3ea-4309c3131cfe.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/a3644f61-c6cd-4ceb-b3ea-4309c3131cfe/a3644f61-c6cd-4ceb-b3ea-4309c3131cfe.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.
Episode 1 follows the clinical chain from lung-cancer screening and pulmonary-nodule evaluation to a tissue diagnosis that can actually guide treatment. We focus on the decisions that...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Thoracic Oncology Edition.<br />Episode 1 follows the clinical chain from lung-cancer screening and pulmonary-nodule evaluation to a tissue diagnosis that can actually guide treatment. We focus on the decisions that prevent downstream staging and planning errors: whether an abnormality belongs on a screening or diagnostic pathway, what to sample, how to judge tissue adequacy, and when additional workup will change management.<br />Use the episode to practice a board-ready four-question framework: define the likely diagnosis, establish the known disease extent, identify the uncertainty most likely to change management, and state the realistic treatment intent.]]></itunes:summary><itunes:duration>1869</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/398345248a5121b35a347fd2b12cb3cc.jpg"/><itunes:episode>1</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E32: Mock Oral Boards Penile and Urethral Cancer, Node-Positive and Preservation Cases</title><link>https://www.spreaker.com/episode/gu-e32-mock-oral-boards-penile-and-urethral-cancer-node-positive-and-preservation-cases--73249549</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Genitourinary Oncology Edition. <br />In Episode 32, we conclude our distal GU module with a deep dive into Mock Oral Boards—focusing on Penile and Urethral Cancer, including node-positive presentations and organ-preservation strategies. <br />These rare malignancies are prime targets for board examinations because they require a disciplined, structured approach to staging, nodal logic, and complex radiation treatment sequencing. Rather than relying on memorized trivia, the examiner is testing your ability to synthesize clinical data and respect anatomical constraints.<br />In this episode, I will walk you through two primary case blocks presented in stages. I encourage you to pause after each question to formulate your own clinical response before listening to the model answer.]]></description><guid isPermaLink="false">ec21f377-dd3c-4bd3-a87d-b2cc76acd57b</guid><pubDate>Thu, 30 Jul 2026 00:28:48 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73249549/38e111f0_168c_ca74_cd43_261f2196af67.mp3" length="42050174" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/8031475d-f9fe-4743-bd5f-8c334cf47765/8031475d-f9fe-4743-bd5f-8c334cf47765.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/8031475d-f9fe-4743-bd5f-8c334cf47765/8031475d-f9fe-4743-bd5f-8c334cf47765.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/8031475d-f9fe-4743-bd5f-8c334cf47765/8031475d-f9fe-4743-bd5f-8c334cf47765.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Genitourinary Oncology Edition. 
In Episode 32, we conclude our distal GU module with a deep dive into Mock Oral Boards—focusing on Penile and Urethral Cancer, including node-positive presentations and...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Genitourinary Oncology Edition. <br />In Episode 32, we conclude our distal GU module with a deep dive into Mock Oral Boards—focusing on Penile and Urethral Cancer, including node-positive presentations and organ-preservation strategies. <br />These rare malignancies are prime targets for board examinations because they require a disciplined, structured approach to staging, nodal logic, and complex radiation treatment sequencing. Rather than relying on memorized trivia, the examiner is testing your ability to synthesize clinical data and respect anatomical constraints.<br />In this episode, I will walk you through two primary case blocks presented in stages. I encourage you to pause after each question to formulate your own clinical response before listening to the model answer.]]></itunes:summary><itunes:duration>2629</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E27: Case-Based Review RCC Mock Oral: Solitary Kidney, IVC, and Oligoprogression</title><link>https://www.spreaker.com/episode/gu-e27-case-based-review-rcc-mock-oral-solitary-kidney-ivc-and-oligoprogression--73249548</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. In Episode 27, we tackle a mock oral exam focused on Renal Cell Carcinoma (RCC), covering clinical scenarios involving a solitary kidney, IVC involvement, and oligoprogression. In this session, I present two primary case blocks, each paired with a contrasting clinical twist. To get the most out of this episode, I encourage you to pause after each question to formulate your own management plan before listening to the model response. RCC management requires nuanced clinical judgment. We will explore the critical decision-making points—balancing the roles of surgery and radiation—and discuss how local therapy can effectively complement systemic regimens without overextending beyond the current evidence base.]]></description><guid isPermaLink="false">0dc6bb16-9561-45e3-a514-1c71ad8c3aea</guid><pubDate>Thu, 30 Jul 2026 00:25:06 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73249548/7a9439e6_e265_63cf_8551_e605d2062530.mp3" length="36941877" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/cb87bee6-6300-4e6b-81de-9360b28ecc8b/cb87bee6-6300-4e6b-81de-9360b28ecc8b.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/cb87bee6-6300-4e6b-81de-9360b28ecc8b/cb87bee6-6300-4e6b-81de-9360b28ecc8b.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/cb87bee6-6300-4e6b-81de-9360b28ecc8b/cb87bee6-6300-4e6b-81de-9360b28ecc8b.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. In Episode 27, we tackle a mock oral exam focused on Renal Cell Carcinoma (RCC), covering clinical scenarios involving a solitary kidney, IVC involvement, and oligoprogression. In...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. In Episode 27, we tackle a mock oral exam focused on Renal Cell Carcinoma (RCC), covering clinical scenarios involving a solitary kidney, IVC involvement, and oligoprogression. In this session, I present two primary case blocks, each paired with a contrasting clinical twist. To get the most out of this episode, I encourage you to pause after each question to formulate your own management plan before listening to the model response. RCC management requires nuanced clinical judgment. We will explore the critical decision-making points—balancing the roles of surgery and radiation—and discuss how local therapy can effectively complement systemic regimens without overextending beyond the current evidence base.]]></itunes:summary><itunes:duration>2309</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E23: Testicular Mock Oral - Stage I, Stage IIA, and NSGCT Variants</title><link>https://www.spreaker.com/episode/gu-e23-testicular-mock-oral-stage-i-stage-iia-and-nsgct-variants--73249552</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. This is Episode 23: Testicular Mock Oral - Stage I, Stage IIA, and NSGCT Variants. Today we cap our testicular block with a full mock oral boards session. I will present three case blocks. Each block includes a main case and a contrasting twist that forces a different management decision. Pause after each question to formulate your own structured response before I give the model answer and the teaching pearl. One framing note before we begin. Testicular germ cell tumor is one of the clearest toxicity-minimization diseases in radiation oncology. In stage I disease, the disease-specific survival is so high that the question is often not “Can you cure him?” It is “Can you cure him without over-treating him?”]]></description><guid isPermaLink="false">e1cc96eb-61b3-4a64-a88c-5842ee77fada</guid><pubDate>Thu, 30 Jul 2026 00:22:33 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73249552/a4b19bc5_ebff_0b51_3d59_729f9b609202.mp3" length="32524884" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/9c90b419-785f-4d1e-8562-323ab7478a40/9c90b419-785f-4d1e-8562-323ab7478a40.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/9c90b419-785f-4d1e-8562-323ab7478a40/9c90b419-785f-4d1e-8562-323ab7478a40.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/9c90b419-785f-4d1e-8562-323ab7478a40/9c90b419-785f-4d1e-8562-323ab7478a40.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. This is Episode 23: Testicular Mock Oral - Stage I, Stage IIA, and NSGCT Variants. Today we cap our testicular block with a full mock oral boards session. I will present three case...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. This is Episode 23: Testicular Mock Oral - Stage I, Stage IIA, and NSGCT Variants. Today we cap our testicular block with a full mock oral boards session. I will present three case blocks. Each block includes a main case and a contrasting twist that forces a different management decision. Pause after each question to formulate your own structured response before I give the model answer and the teaching pearl. One framing note before we begin. Testicular germ cell tumor is one of the clearest toxicity-minimization diseases in radiation oncology. In stage I disease, the disease-specific survival is so high that the question is often not “Can you cure him?” It is “Can you cure him without over-treating him?”]]></itunes:summary><itunes:duration>2033</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E18: Bladder Mock Oral - trimodality therapy, post-cystectomy radiation, and local recurrence</title><link>https://www.spreaker.com/episode/gu-e18-bladder-mock-oral-trimodality-therapy-post-cystectomy-radiation-and-local-recurrence--73248880</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. This is Episode 18: Bladder Mock Oral - trimodality therapy, post-cystectomy radiation, and local recurrence. This is the capstone of the bladder block. The goal today is not just to know doses. The goal is to answer the way an examiner wants to hear it: first define candidacy, then frame the multidisciplinary options, then give a precise treatment plan, and finally show that you understand surveillance and salvage. In bladder cancer, selection comes before prescription.]]></description><guid isPermaLink="false">ca4599e6-ee9d-4d95-b87b-7ec95a591ba6</guid><pubDate>Thu, 30 Jul 2026 00:19:02 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73248880/f05ffcc8_41ce_af97_7442_a0f26082cad4.mp3" length="35992692" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/6b0e30ec-ef85-4680-acf9-d0774d1ef571/6b0e30ec-ef85-4680-acf9-d0774d1ef571.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/6b0e30ec-ef85-4680-acf9-d0774d1ef571/6b0e30ec-ef85-4680-acf9-d0774d1ef571.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/6b0e30ec-ef85-4680-acf9-d0774d1ef571/6b0e30ec-ef85-4680-acf9-d0774d1ef571.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. This is Episode 18: Bladder Mock Oral - trimodality therapy, post-cystectomy radiation, and local recurrence. This is the capstone of the bladder block. The goal today is not just...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. This is Episode 18: Bladder Mock Oral - trimodality therapy, post-cystectomy radiation, and local recurrence. This is the capstone of the bladder block. The goal today is not just to know doses. The goal is to answer the way an examiner wants to hear it: first define candidacy, then frame the multidisciplinary options, then give a precise treatment plan, and finally show that you understand surveillance and salvage. In bladder cancer, selection comes before prescription.]]></itunes:summary><itunes:duration>2250</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E12: Case-Based Review: Prostate Cancer Mock Oral Boards</title><link>https://www.spreaker.com/episode/gu-e12-case-based-review-prostate-cancer-mock-oral-boards--73248881</link><description><![CDATA[Welcome back to Rad Onc Smart Review: Genitourinary Oncology Edition. In Episode 12, we’re putting your knowledge to the test with a Case-Based Review: Prostate Cancer Mock Oral Boards.In this episode, I walk through three distinct case blocks covering intact localized disease, post-prostatectomy salvage, and oligometastatic recurrence. Each block features a primary case followed by a contrasting clinical twist. To get the most out of this session, I recommend pausing after each question to formulate your own structured response before listening to the model answer and key teaching pearl. Let’s begin.]]></description><guid isPermaLink="false">7ec1f556-d18f-4ac1-b567-01a96c12247e</guid><pubDate>Thu, 30 Jul 2026 00:17:04 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/73248881/ed950ad1_9e21_6ee2_6cab_e36d5c760b8a.mp3" length="47830550" type="audio/mpeg"/><podcast:transcript url="https://transcription.spreaker.com/starship/6ffb0471-f6e0-44cb-af76-dd842a1fd79f/6ffb0471-f6e0-44cb-af76-dd842a1fd79f.srt" type="application/x-subrip" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/6ffb0471-f6e0-44cb-af76-dd842a1fd79f/6ffb0471-f6e0-44cb-af76-dd842a1fd79f.txt" type="text/plain" language="en"/><podcast:transcript url="https://transcription.spreaker.com/starship/6ffb0471-f6e0-44cb-af76-dd842a1fd79f/6ffb0471-f6e0-44cb-af76-dd842a1fd79f.vtt" type="text/vtt" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review: Genitourinary Oncology Edition. In Episode 12, we’re putting your knowledge to the test with a Case-Based Review: Prostate Cancer Mock Oral Boards.In this episode, I walk through three distinct case blocks...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review: Genitourinary Oncology Edition. In Episode 12, we’re putting your knowledge to the test with a Case-Based Review: Prostate Cancer Mock Oral Boards.In this episode, I walk through three distinct case blocks covering intact localized disease, post-prostatectomy salvage, and oligometastatic recurrence. Each block features a primary case followed by a contrasting clinical twist. To get the most out of this session, I recommend pausing after each question to formulate your own structured response before listening to the model answer and key teaching pearl. Let’s begin.]]></itunes:summary><itunes:duration>2990</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E31: Penile and Urethral Planning Workshop</title><link>https://www.spreaker.com/episode/gu-e31-penile-and-urethral-planning-workshop--71825042</link><description><![CDATA[This is Episode 31: Penile and Urethral Planning Workshop. These are rare, high-stakes plans. The anatomy is mobile, the setup can be awkward, the evidence base is limited, and sloppy field design can have major consequences. This workstation episode covers simulation, bolus, immobilization, penile brachytherapy, inguinal and pelvic nodal contouring using the InPACT framework, and key principles of urethral cancer planning.]]></description><guid isPermaLink="false">2e7b6b7b-14eb-4ef3-b62a-8f0b6425862f</guid><pubDate>Sat, 02 May 2026 04:00:21 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71825042/2cd66481_53d0_6b2c_708c_205625580a42.mp3" length="36246393" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 31: Penile and Urethral Planning Workshop. These are rare, high-stakes plans. The anatomy is mobile, the setup can be awkward, the evidence base is limited, and sloppy field design can have major consequences. This workstation episode...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 31: Penile and Urethral Planning Workshop. These are rare, high-stakes plans. The anatomy is mobile, the setup can be awkward, the evidence base is limited, and sloppy field design can have major consequences. This workstation episode covers simulation, bolus, immobilization, penile brachytherapy, inguinal and pelvic nodal contouring using the InPACT framework, and key principles of urethral cancer planning.]]></itunes:summary><itunes:duration>2266</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E30: Penile Cancer Primary Management, Nodes &amp; Organ Preservation</title><link>https://www.spreaker.com/episode/gu-e30-penile-cancer-primary-management-nodes-organ-preservation--71825045</link><description><![CDATA[This is Episode 30: Penile Cancer Primary Management, Nodes, and Organ Preservation.Penile cancer is rare, but it is very fair game on boards because it tests whether you can keep anatomy, staging, nodal logic, and quality-of-life tradeoffs straight in a disease most residents will see only rarely.]]></description><guid isPermaLink="false">cc859e16-6117-4065-b782-2ad1f82aff24</guid><pubDate>Sat, 02 May 2026 03:59:09 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71825045/a6df1ef2_5bb4_e50f_65d2_281b420e0164.mp3" length="32653616" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 30: Penile Cancer Primary Management, Nodes, and Organ Preservation.Penile cancer is rare, but it is very fair game on boards because it tests whether you can keep anatomy, staging, nodal logic, and quality-of-life tradeoffs straight...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 30: Penile Cancer Primary Management, Nodes, and Organ Preservation.Penile cancer is rare, but it is very fair game on boards because it tests whether you can keep anatomy, staging, nodal logic, and quality-of-life tradeoffs straight in a disease most residents will see only rarely.]]></itunes:summary><itunes:duration>2041</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E29:Urethral Cancer Staging and Multimodality Management.</title><link>https://www.spreaker.com/episode/gu-e29-urethral-cancer-staging-and-multimodality-management--71825046</link><description><![CDATA[Today we will build a practical framework for workup, staging, histology, and multimodality management. We will also cover where radiation fits, including selected use of brachytherapy for early-stage female disease and definitive chemoradiation for selected locally advanced squamous tumors.]]></description><guid isPermaLink="false">72d01a70-7386-41db-a0ce-775954de3582</guid><pubDate>Sat, 02 May 2026 03:57:25 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71825046/857dbcae_7b5b_83de_a79e_4d1efeec80c5.mp3" length="41388127" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today we will build a practical framework for workup, staging, histology, and multimodality management. We will also cover where radiation fits, including selected use of brachytherapy for early-stage female disease and definitive chemoradiation for...</itunes:subtitle><itunes:summary><![CDATA[Today we will build a practical framework for workup, staging, histology, and multimodality management. We will also cover where radiation fits, including selected use of brachytherapy for early-stage female disease and definitive chemoradiation for selected locally advanced squamous tumors.]]></itunes:summary><itunes:duration>2587</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E28:Upper Tract Urothelial Carcinoma</title><link>https://www.spreaker.com/episode/gu-e28-upper-tract-urothelial-carcinoma--71825050</link><description><![CDATA[This is Episode 28: Upper Tract Urothelial Carcinoma perioperative therapy, patterns of failure, and where radiation enters the conversation.UTUC is one of those diseases that residents do not see often, but oral examiners love it because it looks familiar and then punishes shortcut thinking. The histology overlaps with bladder urothelial carcinoma, but the risk stratification, the surgical planning, the perioperative systemic-therapy logic, and the radiation role are not the same.]]></description><guid isPermaLink="false">306b2045-18a9-4916-8df2-093fbcc61e1d</guid><pubDate>Sat, 02 May 2026 03:54:34 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71825050/df3e1c44_0daf_b399_7e3f_f8c54c970292.mp3" length="42799575" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 28: Upper Tract Urothelial Carcinoma perioperative therapy, patterns of failure, and where radiation enters the conversation.UTUC is one of those diseases that residents do not see often, but oral examiners love it because it looks...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 28: Upper Tract Urothelial Carcinoma perioperative therapy, patterns of failure, and where radiation enters the conversation.UTUC is one of those diseases that residents do not see often, but oral examiners love it because it looks familiar and then punishes shortcut thinking. The histology overlaps with bladder urothelial carcinoma, but the risk stratification, the surgical planning, the perioperative systemic-therapy logic, and the radiation role are not the same.]]></itunes:summary><itunes:duration>2675</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E26: RCC Planning Workshop Primary and Metastatic SBRT Cases</title><link>https://www.spreaker.com/episode/gu-e26-rcc-planning-workshop-primary-and-metastatic-sbrt-cases--71825044</link><description><![CDATA[This is the workstation episode. This is the planning episode. The big idea is simple: kidney SBRT is usually a motion-management problem and an organ-at-risk problem before it becomes a dose problem. Your bowel, your duodenum, your stomach, and the remaining uninvolved renal parenchyma often decide the regimen.]]></description><guid isPermaLink="false">35a8df5a-716b-4a41-91cf-07ea9dd9e881</guid><pubDate>Sat, 02 May 2026 03:52:33 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71825044/15b88f01_5545_48e1_185b_685f5ad58474.mp3" length="43452845" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is the workstation episode. This is the planning episode. The big idea is simple: kidney SBRT is usually a motion-management problem and an organ-at-risk problem before it becomes a dose problem. Your bowel, your duodenum, your stomach, and the...</itunes:subtitle><itunes:summary><![CDATA[This is the workstation episode. This is the planning episode. The big idea is simple: kidney SBRT is usually a motion-management problem and an organ-at-risk problem before it becomes a dose problem. Your bowel, your duodenum, your stomach, and the remaining uninvolved renal parenchyma often decide the regimen.]]></itunes:summary><itunes:duration>2716</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E25: RCC: Oligometastatic Disease, the ICI Era, and Cytoreduction</title><link>https://www.spreaker.com/episode/gu-e25-rcc-oligometastatic-disease-the-ici-era-and-cytoreduction--71825043</link><description><![CDATA[This is one of the highest-yield modern RCC topics because it sits right where three practice changes collide. First, RCC was long treated as a disease that did not respond well to conventional radiation, but modern ablative radiation changed that conversation. Second, cytoreductive nephrectomy went from reflex dogma to a selective, risk-adapted decision. Third, immune checkpoint inhibitor–based combinations became the backbone of first-line metastatic therapy, which means local therapy now has to be placed carefully and honestly into the treatment sequence.]]></description><guid isPermaLink="false">2174f0bc-716d-4061-83fa-8756f2b97c59</guid><pubDate>Sat, 02 May 2026 03:49:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71825043/a8fb0209_5751_cc06_f8e1_2448370b9628.mp3" length="41596270" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is one of the highest-yield modern RCC topics because it sits right where three practice changes collide. First, RCC was long treated as a disease that did not respond well to conventional radiation, but modern ablative radiation changed that...</itunes:subtitle><itunes:summary><![CDATA[This is one of the highest-yield modern RCC topics because it sits right where three practice changes collide. First, RCC was long treated as a disease that did not respond well to conventional radiation, but modern ablative radiation changed that conversation. Second, cytoreductive nephrectomy went from reflex dogma to a selective, risk-adapted decision. Third, immune checkpoint inhibitor–based combinations became the backbone of first-line metastatic therapy, which means local therapy now has to be placed carefully and honestly into the treatment sequence.]]></itunes:summary><itunes:duration>2600</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E24:RCC: Localized Disease, Surgery, Ablation &amp; Primary SBRT</title><link>https://www.spreaker.com/episode/gu-e24-rcc-localized-disease-surgery-ablation-primary-sbrt--71825054</link><description><![CDATA[This is Episode 24: Renal Cell Carcinoma Localized Disease, Surgery, Ablation, and Primary SBRT. Here is the modern frame. Localized RCC is still primarily a surgical disease. Conventional fractionation never established a curative or adjuvant role in this setting. But stereotactic ablative body radiotherapy has changed the conversation for selected patients who are medically inoperable, technically high risk for surgery, or who decline surgery.]]></description><guid isPermaLink="false">4a3898ef-bf90-4741-a6fd-aaed52d0e4ef</guid><pubDate>Sat, 02 May 2026 03:44:42 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71825054/edbb5b34_902e_8e4d_4011_7685f9640dc8.mp3" length="34710393" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 24: Renal Cell Carcinoma Localized Disease, Surgery, Ablation, and Primary SBRT. Here is the modern frame. Localized RCC is still primarily a surgical disease. Conventional fractionation never established a curative or adjuvant role in...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 24: Renal Cell Carcinoma Localized Disease, Surgery, Ablation, and Primary SBRT. Here is the modern frame. Localized RCC is still primarily a surgical disease. Conventional fractionation never established a curative or adjuvant role in this setting. But stereotactic ablative body radiotherapy has changed the conversation for selected patients who are medically inoperable, technically high risk for surgery, or who decline surgery.]]></itunes:summary><itunes:duration>2170</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E22:Testicular: Fertility, Toxicity, Follow-up &amp; Failure Patterns</title><link>https://www.spreaker.com/episode/gu-e22-testicular-fertility-toxicity-follow-up-failure-patterns--71825048</link><description><![CDATA[This episode is about what happens after cure. Testicular cancer is one of the great success stories in oncology, but that success creates a second job: taking care of survivors for decades. These are often young men with excellent cure rates and long life expectancy. So the real question is not just whether you cured the cancer. It is whether you protected fertility, recognized relapse on the right schedule, and minimized the long-term cost of treatment.]]></description><guid isPermaLink="false">15f3f94a-7621-4ad7-a05d-4f522b78af52</guid><pubDate>Sat, 02 May 2026 03:43:29 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71825048/c0dfcd91_0252_196f_7dc1_e5c8ef013a62.mp3" length="31404336" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This episode is about what happens after cure. Testicular cancer is one of the great success stories in oncology, but that success creates a second job: taking care of survivors for decades. These are often young men with excellent cure rates and long...</itunes:subtitle><itunes:summary><![CDATA[This episode is about what happens after cure. Testicular cancer is one of the great success stories in oncology, but that success creates a second job: taking care of survivors for decades. These are often young men with excellent cure rates and long life expectancy. So the real question is not just whether you cured the cancer. It is whether you protected fertility, recognized relapse on the right schedule, and minimized the long-term cost of treatment.]]></itunes:summary><itunes:duration>1963</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E21: Testicular: Advanced GCT, Residual Masses, and Salvage Strategy</title><link>https://www.spreaker.com/episode/gu-e21-testicular-advanced-gct-residual-masses-and-salvage-strategy--71825047</link><description><![CDATA[This is the episode where testicular cancer stops being mostly about stage I and stage II decision trees and starts becoming a sequencing problem. The questions are no longer just surveillance versus adjuvant therapy. Now the important questions are: how do you classify risk correctly, which chemotherapy backbone belongs to which group, when does PET help, when does it not help at all, who needs surgery after chemotherapy, and what exactly do you do when the disease comes back.]]></description><guid isPermaLink="false">958e0833-673e-4c3e-bf70-717e5d8b5404</guid><pubDate>Sat, 02 May 2026 03:42:15 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71825047/8e7563f0_0d69_95e0_c6ee_409fedcf2373.mp3" length="39656522" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is the episode where testicular cancer stops being mostly about stage I and stage II decision trees and starts becoming a sequencing problem. The questions are no longer just surveillance versus adjuvant therapy. Now the important questions are:...</itunes:subtitle><itunes:summary><![CDATA[This is the episode where testicular cancer stops being mostly about stage I and stage II decision trees and starts becoming a sequencing problem. The questions are no longer just surveillance versus adjuvant therapy. Now the important questions are: how do you classify risk correctly, which chemotherapy backbone belongs to which group, when does PET help, when does it not help at all, who needs surgery after chemotherapy, and what exactly do you do when the disease comes back.]]></itunes:summary><itunes:duration>2479</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E20:Testicular Stage II Seminoma, NSGCT, and Field Design</title><link>https://www.spreaker.com/episode/gu-e20-testicular-stage-ii-seminoma-nsgct-and-field-design--71580587</link><description><![CDATA[This is Episode 20: Testicular Stage II Seminoma, NSGCT, and Field Design. Last episode, we built the foundation: markers, orchiectomy, staging, and why surveillance is preferred for most stage I seminoma. Today we move into stage II disease, where the question is no longer just whether you know the basics. The question is whether you can choose treatment, explain why, and, if needed, describe a radiation field clearly and defensibly.]]></description><guid isPermaLink="false">fedc36a2-3a56-4fc8-be05-225e500aa9b1</guid><pubDate>Thu, 23 Apr 2026 01:48:51 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580587/ba877c9e_0aab_1987_dee5_509c36abdd38.mp3" length="40990230" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 20: Testicular Stage II Seminoma, NSGCT, and Field Design. Last episode, we built the foundation: markers, orchiectomy, staging, and why surveillance is preferred for most stage I seminoma. Today we move into stage II disease, where...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 20: Testicular Stage II Seminoma, NSGCT, and Field Design. Last episode, we built the foundation: markers, orchiectomy, staging, and why surveillance is preferred for most stage I seminoma. Today we move into stage II disease, where the question is no longer just whether you know the basics. The question is whether you can choose treatment, explain why, and, if needed, describe a radiation field clearly and defensibly.]]></itunes:summary><itunes:duration>2562</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E19: Testicular Cancer Workup, Markers, Staging, and Stage I Seminoma</title><link>https://www.spreaker.com/episode/gu-e19-testicular-cancer-workup-markers-staging-and-stage-i-seminoma--71580586</link><description><![CDATA[This is Episode 19: Testicular Cancer - Workup, Markers, Staging, and Stage I Seminoma. Testicular cancer is uncommon overall, but it is the most common solid malignancy in young men, and it is one of the great cure stories in oncology. That changes the way we think about treatment. The question is often not whether cure is possible. The question is how to preserve cure while minimizing overtreatment and long-term toxicity in a patient who may live for decades.]]></description><guid isPermaLink="false">80201857-cc5e-433d-b70b-267baf8c88d3</guid><pubDate>Thu, 23 Apr 2026 01:47:19 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580586/0ef96225_78bc_fd77_11aa_8d9f3aa1dfef.mp3" length="32265750" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 19: Testicular Cancer - Workup, Markers, Staging, and Stage I Seminoma. Testicular cancer is uncommon overall, but it is the most common solid malignancy in young men, and it is one of the great cure stories in oncology. That changes...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 19: Testicular Cancer - Workup, Markers, Staging, and Stage I Seminoma. Testicular cancer is uncommon overall, but it is the most common solid malignancy in young men, and it is one of the great cure stories in oncology. That changes the way we think about treatment. The question is often not whether cure is possible. The question is how to preserve cure while minimizing overtreatment and long-term toxicity in a patient who may live for decades.]]></itunes:summary><itunes:duration>2017</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E17: Metastatic urothelial cancer, immunotherapy, and future directions</title><link>https://www.spreaker.com/episode/gu-e17-metastatic-urothelial-cancer-immunotherapy-and-future-directions--71580591</link><description><![CDATA[This is Episode 17: metastatic urothelial cancer, immunotherapy, and future directions. This is one of the fastest-moving areas in GU oncology. For years, first-line treatment for metastatic urothelial cancer meant platinum-based chemotherapy, with median overall survival in the mid-teens. That changed with EV-302. For many patients, the preferred first-line regimen is now enfortumab vedotin plus pembrolizumab. This is a major practice shift and is absolutely board-relevant.]]></description><guid isPermaLink="false">3845ae5c-4013-433c-a836-bb05df0e8530</guid><pubDate>Thu, 23 Apr 2026 01:46:05 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580591/90c0c737_c197_5d09_bebd_821595ed03b8.mp3" length="39134073" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 17: metastatic urothelial cancer, immunotherapy, and future directions. This is one of the fastest-moving areas in GU oncology. For years, first-line treatment for metastatic urothelial cancer meant platinum-based chemotherapy, with...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 17: metastatic urothelial cancer, immunotherapy, and future directions. This is one of the fastest-moving areas in GU oncology. For years, first-line treatment for metastatic urothelial cancer meant platinum-based chemotherapy, with median overall survival in the mid-teens. That changed with EV-302. For many patients, the preferred first-line regimen is now enfortumab vedotin plus pembrolizumab. This is a major practice shift and is absolutely board-relevant.]]></itunes:summary><itunes:duration>2446</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E16: Bladder Post-Cystectomy Radiation, Follow-Up, and Salvage Pathways.</title><link>https://www.spreaker.com/episode/gu-e16-bladder-post-cystectomy-radiation-follow-up-and-salvage-pathways--71580595</link><description><![CDATA[This is Episode 16: Bladder Post-Cystectomy Radiation, Follow-Up, and Salvage Pathways. This episode is high-yield because it addresses two common bladder cancer mistakes. First, it corrects the simplistic answer that radiation has no role after cystectomy. Second, it clarifies the need to act promptly when a patient, previously treated with trimodality therapy, experiences an invasive recurrence. In modern board-style teaching, this episode covers selective postoperative radiation for high-risk pathology and the importance of recognizing when salvage cystectomy is necessary.]]></description><guid isPermaLink="false">6f8fa833-d90a-497d-a588-fcf4f9acd784</guid><pubDate>Thu, 23 Apr 2026 01:44:41 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580595/c0916e7a_bebe_51c3_6092_b3ff682fb784.mp3" length="41093884" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 16: Bladder Post-Cystectomy Radiation, Follow-Up, and Salvage Pathways. This episode is high-yield because it addresses two common bladder cancer mistakes. First, it corrects the simplistic answer that radiation has no role after...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 16: Bladder Post-Cystectomy Radiation, Follow-Up, and Salvage Pathways. This episode is high-yield because it addresses two common bladder cancer mistakes. First, it corrects the simplistic answer that radiation has no role after cystectomy. Second, it clarifies the need to act promptly when a patient, previously treated with trimodality therapy, experiences an invasive recurrence. In modern board-style teaching, this episode covers selective postoperative radiation for high-risk pathology and the importance of recognizing when salvage cystectomy is necessary.]]></itunes:summary><itunes:duration>2569</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E15: Bladder Planning Workshop Definitive Preservation Cases</title><link>https://www.spreaker.com/episode/gu-e15-bladder-planning-workshop-definitive-preservation-cases--71580590</link><description><![CDATA[This is Episode 15: Bladder Planning Workshop - Definitive Preservation Cases. The last episode focused on who qualifies for trimodality therapy and why concurrent chemoradiation is preferred over radiation alone. Today's planning episode covers how to simulate, contour, choose volumes, and make technically defensible decisions when the bladder is moving, deforming, and sitting right next to the small bowel.]]></description><guid isPermaLink="false">fef1f169-15c5-426b-8e10-4f7559ec0dce</guid><pubDate>Thu, 23 Apr 2026 01:43:23 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580590/d74e537d_c2cc_05b0_eb4e_d433c2327bd2.mp3" length="42809188" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 15: Bladder Planning Workshop - Definitive Preservation Cases. The last episode focused on who qualifies for trimodality therapy and why concurrent chemoradiation is preferred over radiation alone. Today's planning episode covers how...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 15: Bladder Planning Workshop - Definitive Preservation Cases. The last episode focused on who qualifies for trimodality therapy and why concurrent chemoradiation is preferred over radiation alone. Today's planning episode covers how to simulate, contour, choose volumes, and make technically defensible decisions when the bladder is moving, deforming, and sitting right next to the small bowel.]]></itunes:summary><itunes:duration>2676</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E14: Bladder Trimodality Therapy, Radiosensitizers, and Hypofractionation.</title><link>https://www.spreaker.com/episode/gu-e14-bladder-trimodality-therapy-radiosensitizers-and-hypofractionation--71580596</link><description><![CDATA[This is Episode 14: Bladder Trimodality Therapy, Radiosensitizers, and Hypofractionation. Here's the key takeaway: bladder-preserving trimodality therapy is a viable curative option, not a last resort. In the right patients, it's a legitimate strategy, deserving of discussion alongside radical cystectomy. To excel on exams, present it correctly: prioritize candidate selection, use concurrent radiosensitizers, and incorporate salvage planning from the outset.]]></description><guid isPermaLink="false">b6477dd5-86b4-4ae8-9f67-5229a1e0b193</guid><pubDate>Thu, 23 Apr 2026 01:41:46 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580596/d2576fed_de8f_a9b6_05b2_9998cf4bd2b7.mp3" length="41517276" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 14: Bladder Trimodality Therapy, Radiosensitizers, and Hypofractionation. Here's the key takeaway: bladder-preserving trimodality therapy is a viable curative option, not a last resort. In the right patients, it's a legitimate...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 14: Bladder Trimodality Therapy, Radiosensitizers, and Hypofractionation. Here's the key takeaway: bladder-preserving trimodality therapy is a viable curative option, not a last resort. In the right patients, it's a legitimate strategy, deserving of discussion alongside radical cystectomy. To excel on exams, present it correctly: prioritize candidate selection, use concurrent radiosensitizers, and incorporate salvage planning from the outset.]]></itunes:summary><itunes:duration>2595</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E13: Bladder Cancer NMIBC, MIBC Workup and the Surgical Backbone</title><link>https://www.spreaker.com/episode/gu-e13-bladder-cancer-nmibc-mibc-workup-and-the-surgical-backbone--71580589</link><description><![CDATA[This is Episode 13: Bladder Cancer – Non-Muscle-Invasive and Muscle-Invasive Workup and the Surgical Backbone. Here's why this episode matters: Bladder cancer is a disease where radiation oncologists can be indispensable members of a curative bladder-preservation team, or completely absent from meaningful treatment discussions. The difference often comes down to understanding the surgical and medical backbone of the disease. You cannot intelligently argue for trimodality therapy in a tumor board if you don't understand what a quality TURBT looks like, when repeat TURBT is needed, what cisplatin-based perioperative therapy aims to achieve, and which patients benefit most from radical cystectomy.]]></description><guid isPermaLink="false">57d8f7d8-43d3-496e-8a21-6bcfa798baf7</guid><pubDate>Thu, 23 Apr 2026 01:40:41 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580589/22755a1c_2341_85a9_fadb_717c7d5a3d37.mp3" length="33733622" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 13: Bladder Cancer – Non-Muscle-Invasive and Muscle-Invasive Workup and the Surgical Backbone. Here's why this episode matters: Bladder cancer is a disease where radiation oncologists can be indispensable members of a curative...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 13: Bladder Cancer – Non-Muscle-Invasive and Muscle-Invasive Workup and the Surgical Backbone. Here's why this episode matters: Bladder cancer is a disease where radiation oncologists can be indispensable members of a curative bladder-preservation team, or completely absent from meaningful treatment discussions. The difference often comes down to understanding the surgical and medical backbone of the disease. You cannot intelligently argue for trimodality therapy in a tumor board if you don't understand what a quality TURBT looks like, when repeat TURBT is needed, what cisplatin-based perioperative therapy aims to achieve, and which patients benefit most from radical cystectomy.]]></itunes:summary><itunes:duration>2109</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E11: Prostate Follow-up, Toxicity, Survivorship, and Failure Patterns</title><link>https://www.spreaker.com/episode/gu-e11-prostate-follow-up-toxicity-survivorship-and-failure-patterns--71580599</link><description><![CDATA[This is Episode 11: Prostate Follow-up, Toxicity, Survivorship, and Failure Patterns. This is a high-yield episode because most prostate teaching focuses on the front end: risk stratification, dose, fractionation, and ADT duration. However, in the real clinic, a huge share of what you do is follow-up. You will spend more time interpreting PSA trends, counseling men about late effects, and managing survivorship than you ever spent simulating the original plan.]]></description><guid isPermaLink="false">c7ec168f-f525-437d-85c0-88037f3ad192</guid><pubDate>Thu, 23 Apr 2026 01:39:04 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580599/5e03db95_c698_af41_0a4d_5ca771a52e1a.mp3" length="40425567" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 11: Prostate Follow-up, Toxicity, Survivorship, and Failure Patterns. This is a high-yield episode because most prostate teaching focuses on the front end: risk stratification, dose, fractionation, and ADT duration. However, in the...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 11: Prostate Follow-up, Toxicity, Survivorship, and Failure Patterns. This is a high-yield episode because most prostate teaching focuses on the front end: risk stratification, dose, fractionation, and ADT duration. However, in the real clinic, a huge share of what you do is follow-up. You will spend more time interpreting PSA trends, counseling men about late effects, and managing survivorship than you ever spent simulating the original plan.]]></itunes:summary><itunes:duration>2527</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E10: Prostate Planning Workshop intact, post-op, and nodal cases</title><link>https://www.spreaker.com/episode/gu-e10-prostate-planning-workshop-intact-post-op-and-nodal-cases--71580592</link><description><![CDATA[This is Episode 10: Prostate Planning Workshop intact, post-op, and nodal cases. For the last several episodes, we've discussed what to treat in prostate cancer – risk groups, ADT duration, brachy boost candidates, and salvage triggers. Today, we're flipping the camera around and talking about how you actually deliver that plan. This is the episode where we sit down at the contouring station together.]]></description><guid isPermaLink="false">93b5f5ba-ef5a-4e98-8a21-2f9a10caab3d</guid><pubDate>Thu, 23 Apr 2026 01:37:59 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580592/755046d2_2a58_c376_82da_7bb9467fb74c.mp3" length="42496555" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 10: Prostate Planning Workshop intact, post-op, and nodal cases. For the last several episodes, we've discussed what to treat in prostate cancer – risk groups, ADT duration, brachy boost candidates, and salvage triggers. Today, we're...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 10: Prostate Planning Workshop intact, post-op, and nodal cases. For the last several episodes, we've discussed what to treat in prostate cancer – risk groups, ADT duration, brachy boost candidates, and salvage triggers. Today, we're flipping the camera around and talking about how you actually deliver that plan. This is the episode where we sit down at the contouring station together.]]></itunes:summary><itunes:duration>2656</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU 09: Prostate mHSPC, CRPC, MDT, and Precision Systemic Therapy</title><link>https://www.spreaker.com/episode/gu-09-prostate-mhspc-crpc-mdt-and-precision-systemic-therapy--71580597</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. This is Episode 9: a discussion on prostate cancer across the metastatic continuum, including metastatic hormone-sensitive disease, nonmetastatic castration-resistant disease, metastatic castration-resistant disease, metastasis-directed therapy, and precision systemic therapy. We'll cover how to move from localized to advanced disease by defining the disease state, the burden, and how biomarkers impact management.]]></description><guid isPermaLink="false">1a55020c-5a53-4634-b052-eef5012d4ace</guid><pubDate>Thu, 23 Apr 2026 01:36:29 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580597/66854297_f1ca_51d1_a017_c02a283581c7.mp3" length="37262034" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. This is Episode 9: a discussion on prostate cancer across the metastatic continuum, including metastatic hormone-sensitive disease, nonmetastatic castration-resistant disease,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Genitourinary Oncology edition. This is Episode 9: a discussion on prostate cancer across the metastatic continuum, including metastatic hormone-sensitive disease, nonmetastatic castration-resistant disease, metastatic castration-resistant disease, metastasis-directed therapy, and precision systemic therapy. We'll cover how to move from localized to advanced disease by defining the disease state, the burden, and how biomarkers impact management.]]></itunes:summary><itunes:duration>2329</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E08:Prostate Salvage After Surgery, RT, and Focal Therapy</title><link>https://www.spreaker.com/episode/gu-e08-prostate-salvage-after-surgery-rt-and-focal-therapy--71580600</link><description><![CDATA[Episodes 3 through 7 covered definitive treatment. This episode covers what to do when definitive treatment fails. After prostatectomy, earlier salvage RT at lower PSA is associated with better outcomes. After prior RT or focal therapy, salvage can still be curative in selected patients, but it requires careful restaging and biopsy confirmation before local retreatment. Today we will cover four things: the shift from routine adjuvant RT to early salvage RT after prostatectomy, the selective role of ADT and pelvic nodal coverage in the salvage setting, the workup for recurrence after RT or focal therapy, and the major salvage options for radiorecurrent disease.]]></description><guid isPermaLink="false">f1575476-a37b-46bf-9a8b-499a5164c71b</guid><pubDate>Thu, 23 Apr 2026 01:34:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71580600/b3b80d3e_672a_4430_d392_506b568e228b.mp3" length="34004460" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Episodes 3 through 7 covered definitive treatment. This episode covers what to do when definitive treatment fails. After prostatectomy, earlier salvage RT at lower PSA is associated with better outcomes. After prior RT or focal therapy, salvage can...</itunes:subtitle><itunes:summary><![CDATA[Episodes 3 through 7 covered definitive treatment. This episode covers what to do when definitive treatment fails. After prostatectomy, earlier salvage RT at lower PSA is associated with better outcomes. After prior RT or focal therapy, salvage can still be curative in selected patients, but it requires careful restaging and biopsy confirmation before local retreatment. Today we will cover four things: the shift from routine adjuvant RT to early salvage RT after prostatectomy, the selective role of ADT and pelvic nodal coverage in the salvage setting, the workup for recurrence after RT or focal therapy, and the major salvage options for radiorecurrent disease.]]></itunes:summary><itunes:duration>2126</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E04: Prostate Definitive EBRT, Dose Escalation &amp; Moderate Hypofractionation</title><link>https://www.spreaker.com/episode/gu-e04-prostate-definitive-ebrt-dose-escalation-moderate-hypofractionation--71171997</link><description><![CDATA[The first three episodes established the foundation – anatomy, risk groups, workup, and surveillance. Now, we begin treatment. This episode explores the physics and biology of dose delivery to the prostate. We'll cover three key areas: First, the benefits of higher doses for biochemical control and what long-term data reveals about distant metastasis and cancer-specific mortality. Second, the rise of moderate hypofractionation as the standard of care, including supporting trials, radiobiologic principles, and important toxicity signals. Third, the FLAME concept – boosting the MRI-visible dominant lesion – and the importance of prioritizing OAR constraints.]]></description><guid isPermaLink="false">ba2e0c57-c1b8-4c70-bbc1-cd0cba5960fb</guid><pubDate>Tue, 31 Mar 2026 15:24:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71171997/8ca929d6_c005_e429_8581_613d9b6b9321.mp3" length="65828290" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>The first three episodes established the foundation – anatomy, risk groups, workup, and surveillance. Now, we begin treatment. This episode explores the physics and biology of dose delivery to the prostate. We'll cover three key areas: First, the...</itunes:subtitle><itunes:summary><![CDATA[The first three episodes established the foundation – anatomy, risk groups, workup, and surveillance. Now, we begin treatment. This episode explores the physics and biology of dose delivery to the prostate. We'll cover three key areas: First, the benefits of higher doses for biochemical control and what long-term data reveals about distant metastasis and cancer-specific mortality. Second, the rise of moderate hypofractionation as the standard of care, including supporting trials, radiobiologic principles, and important toxicity signals. Third, the FLAME concept – boosting the MRI-visible dominant lesion – and the importance of prioritizing OAR constraints.]]></itunes:summary><itunes:duration>4115</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E07</title><link>https://www.spreaker.com/episode/gu-e07--71022875</link><description><![CDATA[E07 Draft]]></description><guid isPermaLink="false">627cd363-1010-4625-bfdb-d465d27d3931</guid><pubDate>Tue, 31 Mar 2026 15:23:17 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71022875/9c27f676_ec7f_7409_e3f1_2be418b84e91.mp3" length="45380473" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>E07 Draft</itunes:subtitle><itunes:summary><![CDATA[E07 Draft]]></itunes:summary><itunes:duration>2837</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E06</title><link>https://www.spreaker.com/episode/gu-e06--71022877</link><description><![CDATA[E06 draft]]></description><guid isPermaLink="false">f4738c77-6e58-4273-97bd-b9849badae1a</guid><pubDate>Tue, 31 Mar 2026 15:22:33 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71022877/b068cc41_c9d7_9f0f_349e_b9514acd6b95.mp3" length="46599660" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>E06 draft</itunes:subtitle><itunes:summary><![CDATA[E06 draft]]></itunes:summary><itunes:duration>2913</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E05</title><link>https://www.spreaker.com/episode/gu-e05--71022878</link><description><![CDATA[E05 draft]]></description><guid isPermaLink="false">ff623e45-9e11-493b-b08e-bc4f6c0656a9</guid><pubDate>Tue, 31 Mar 2026 15:21:52 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71022878/b92f1b3b_608d_b101_5151_88282c1753cb.mp3" length="47804218" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>E05 draft</itunes:subtitle><itunes:summary><![CDATA[E05 draft]]></itunes:summary><itunes:duration>2988</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E03</title><link>https://www.spreaker.com/episode/gu-e03--71022880</link><description><![CDATA[Episode 3 draft]]></description><guid isPermaLink="false">d7f34b22-3479-4559-86dd-641dc268e3ff</guid><pubDate>Tue, 31 Mar 2026 15:21:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71022880/3507f7a1_3cf4_6c7a_553a_fc99c76d0cc0.mp3" length="56697554" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Episode 3 draft</itunes:subtitle><itunes:summary><![CDATA[Episode 3 draft]]></itunes:summary><itunes:duration>3544</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E02</title><link>https://www.spreaker.com/episode/gu-e02--71022876</link><description><![CDATA[Episode 2 draft]]></description><guid isPermaLink="false">f90764a9-11fc-47b6-b4dd-f3b8e1508f90</guid><pubDate>Tue, 31 Mar 2026 15:20:17 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71022876/fe5b03aa_3556_61b0_ae51_9f6199f50638.mp3" length="49295497" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Episode 2 draft</itunes:subtitle><itunes:summary><![CDATA[Episode 2 draft]]></itunes:summary><itunes:duration>3081</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GU E01: Prostate Anatomy, Pathology, Risk Groups &amp; Natural History</title><link>https://www.spreaker.com/episode/gu-e01-prostate-anatomy-pathology-risk-groups-natural-history--71015573</link><description><![CDATA[This is Episode 1: Prostate – Anatomy, Pathology, Risk Groups, and Natural History. This foundational episode covers everything in the prostate series – dose escalation, hypofractionation, brachytherapy, ADT integration, salvage, and oligometastatic management – as we delve deep into three key areas. First, prostate anatomy, including zonal architecture, lymphatic drainage, and adjacent structures that influence local cancer extension and target volume design. Second, risk stratification using Grade Group, PSA, T stage, and biopsy tumor volume – the four key variables for prostate cancer patient classification. Third, natural history, examining landmark data to identify aggressive cancers, understand non-lethal cases, and apply competing-risk thinking to determine appropriate treatment strategies.]]></description><guid isPermaLink="false">276277bf-f828-40bd-ba6a-50f2465d516e</guid><pubDate>Tue, 31 Mar 2026 07:52:06 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/71015573/db5abb91_b70f_3c52_32c3_15115b7d8246.mp3" length="45651310" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 1: Prostate – Anatomy, Pathology, Risk Groups, and Natural History. This foundational episode covers everything in the prostate series – dose escalation, hypofractionation, brachytherapy, ADT integration, salvage, and oligometastatic...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 1: Prostate – Anatomy, Pathology, Risk Groups, and Natural History. This foundational episode covers everything in the prostate series – dose escalation, hypofractionation, brachytherapy, ADT integration, salvage, and oligometastatic management – as we delve deep into three key areas. First, prostate anatomy, including zonal architecture, lymphatic drainage, and adjacent structures that influence local cancer extension and target volume design. Second, risk stratification using Grade Group, PSA, T stage, and biopsy tumor volume – the four key variables for prostate cancer patient classification. Third, natural history, examining landmark data to identify aggressive cancers, understand non-lethal cases, and apply competing-risk thinking to determine appropriate treatment strategies.]]></itunes:summary><itunes:duration>2854</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/fe537cc13e6856ff0ee801c4131ad49d.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E39A: Sinonasal II Maxillary and Ethmoid SCC and SNUC Management</title><link>https://www.spreaker.com/episode/h-n-e39a-sinonasal-ii-maxillary-and-ethmoid-scc-and-snuc-management--70101504</link><description><![CDATA[This is Episode 39a: Sinonasal II Maxillary and Ethmoid SCC and SNUC Management. In our last episode, we established the anatomic and histologic foundations for sinonasal cancers. Now, we apply that knowledge. This clinical decision-making episode will guide you through NCCN algorithms for maxillary and ethmoid sinus tumors. We'll cover recommending elective neck irradiation, orbital preservation vs. exenteration, and the induction chemotherapy paradigm for SNUC, which has revolutionized the management of aggressive sinonasal tumors. The episode uses two cases to represent the clinical scenarios you'll encounter on oral boards: a resectable maxillary sinus SCC and a SNUC with skull base involvement. By the end, you'll confidently navigate both algorithms.]]></description><guid isPermaLink="false">82b5bad2-6cfc-43e9-b910-580b940bee3b</guid><pubDate>Tue, 17 Feb 2026 15:06:06 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/70101504/51d594f2_5617_31ef_e500_96a8f1ad0ea8.mp3" length="37076460" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 39a: Sinonasal II Maxillary and Ethmoid SCC and SNUC Management. In our last episode, we established the anatomic and histologic foundations for sinonasal cancers. Now, we apply that knowledge. This clinical decision-making episode...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 39a: Sinonasal II Maxillary and Ethmoid SCC and SNUC Management. In our last episode, we established the anatomic and histologic foundations for sinonasal cancers. Now, we apply that knowledge. This clinical decision-making episode will guide you through NCCN algorithms for maxillary and ethmoid sinus tumors. We'll cover recommending elective neck irradiation, orbital preservation vs. exenteration, and the induction chemotherapy paradigm for SNUC, which has revolutionized the management of aggressive sinonasal tumors. The episode uses two cases to represent the clinical scenarios you'll encounter on oral boards: a resectable maxillary sinus SCC and a SNUC with skull base involvement. By the end, you'll confidently navigate both algorithms.]]></itunes:summary><itunes:duration>2318</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E38A: Sinonasal I Anatomy, Histology Diversity, and Multimodality Logic</title><link>https://www.spreaker.com/episode/h-n-e38a-sinonasal-i-anatomy-histology-diversity-and-multimodality-logic--70074553</link><description><![CDATA[This is Episode 38: Sinonasal I Anatomy, Histology Diversity, and Multimodality Logic. We are now entering a block of head and neck oncology that is genuinely unique. Sinonasal cancers represent fewer than 2,000 cases per year in the United States — less than 1% of all malignancies — yet they pack an outsized punch on written and oral board examinations. Why? Because these tumors test everything at once. You need to know complex three-dimensional anatomy at the interface of the skull base, orbit, and brain. You need to navigate a histologic landscape unlike any other site in the head and neck, where SCC predominates, but a long tail of histologically distinct tumors — esthesioneuroblastoma, adenoid cystic carcinoma, SNUC, mucosal melanoma, and others — each demand fundamentally different management algorithms. And you need to understand why multimodality therapy is the default — not because of randomized trials, which essentially do not exist — but because the retrospective evidence and the anatomic realities of this site demand it. This episode is your anatomic and conceptual foundation. We will map the sinuses and nasal cavity in board-relevant detail, walk through the histology types you must recognize on sight, learn two separate staging systems, and understand the evidence behind the multimodality paradigm. In subsequent episodes, we will tackle site-specific and histology-specific management, planning around the orbit and skull base, and esthesioneuroblastoma as its own entity.]]></description><guid isPermaLink="false">fae74d01-061d-4615-a337-f41ea5f740fa</guid><pubDate>Mon, 16 Feb 2026 00:09:12 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/70074553/16ccda77_0ae8_afa2_4fb1_9838ebf02404.mp3" length="27756806" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 38: Sinonasal I Anatomy, Histology Diversity, and Multimodality Logic. We are now entering a block of head and neck oncology that is genuinely unique. Sinonasal cancers represent fewer than 2,000 cases per year in the United States —...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 38: Sinonasal I Anatomy, Histology Diversity, and Multimodality Logic. We are now entering a block of head and neck oncology that is genuinely unique. Sinonasal cancers represent fewer than 2,000 cases per year in the United States — less than 1% of all malignancies — yet they pack an outsized punch on written and oral board examinations. Why? Because these tumors test everything at once. You need to know complex three-dimensional anatomy at the interface of the skull base, orbit, and brain. You need to navigate a histologic landscape unlike any other site in the head and neck, where SCC predominates, but a long tail of histologically distinct tumors — esthesioneuroblastoma, adenoid cystic carcinoma, SNUC, mucosal melanoma, and others — each demand fundamentally different management algorithms. And you need to understand why multimodality therapy is the default — not because of randomized trials, which essentially do not exist — but because the retrospective evidence and the anatomic realities of this site demand it. This episode is your anatomic and conceptual foundation. We will map the sinuses and nasal cavity in board-relevant detail, walk through the histology types you must recognize on sight, learn two separate staging systems, and understand the evidence behind the multimodality paradigm. In subsequent episodes, we will tackle site-specific and histology-specific management, planning around the orbit and skull base, and esthesioneuroblastoma as its own entity.]]></itunes:summary><itunes:duration>1735</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E37B: Salivary Gland Capstone Mock Oral Board Review</title><link>https://www.spreaker.com/episode/h-n-e37b-salivary-gland-capstone-mock-oral-board-review--70010738</link><description><![CDATA[Today we simulate the oral boards exam in three clinical blocks plus a lightning round. Block One walks through comprehensive postoperative management. Blocks Two and Three test specific decision pivots, perineural invasion stop points and metastatic biomarker-driven therapy. Then we close with rapid-fire pearls.]]></description><guid isPermaLink="false">03bda686-378e-40ed-8d7d-8c31afc0efe0</guid><pubDate>Thu, 12 Feb 2026 08:29:48 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/70010738/ed38dbd0_29ae_b635_e2ad_6a9b5a611e82.mp3" length="28822602" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1cs5fz3QhsNQIQh9v9ZXcx/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today we simulate the oral boards exam in three clinical blocks plus a lightning round. Block One walks through comprehensive postoperative management. Blocks Two and Three test specific decision pivots, perineural invasion stop points and metastatic...</itunes:subtitle><itunes:summary><![CDATA[Today we simulate the oral boards exam in three clinical blocks plus a lightning round. Block One walks through comprehensive postoperative management. Blocks Two and Three test specific decision pivots, perineural invasion stop points and metastatic biomarker-driven therapy. Then we close with rapid-fire pearls.]]></itunes:summary><itunes:duration>1802</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E37A: Salivary Gland IV Unresectable Disease and Advanced Approaches</title><link>https://www.spreaker.com/episode/h-n-e37a-salivary-gland-iv-unresectable-disease-and-advanced-approaches--70010739</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 37: Salivary Gland Four – Unresectable Disease and Advanced Approaches. This episode completes our Salivary Gland block. We have built the foundation – histology-driven biology in Episode 34, adjuvant R-T triggers and planning in Episode 35, and perineural invasion strategy in Episode 36. Today we address difficult cases: the patient who cannot undergo surgery, the tumor that recurs despite our best efforts, and the adenoid cystic carcinoma that metastasizes to the lungs years after we thought we had won. We will also cover a rapidly evolving area – biomarker-driven systemic therapy. This is where salivary gland oncology is changing fastest, and the board examiners know it.]]></description><guid isPermaLink="false">733e4b9a-aaa6-4618-b594-a9773e97725f</guid><pubDate>Thu, 12 Feb 2026 08:28:32 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/70010739/d2d2303e_6796_c778_748e_6646bd90ff5c.mp3" length="36177012" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7djIK61R0fnC5r71O20l1k/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 37: Salivary Gland Four – Unresectable Disease and Advanced Approaches. This episode completes our Salivary Gland block. We have built the foundation – histology-driven...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 37: Salivary Gland Four – Unresectable Disease and Advanced Approaches. This episode completes our Salivary Gland block. We have built the foundation – histology-driven biology in Episode 34, adjuvant R-T triggers and planning in Episode 35, and perineural invasion strategy in Episode 36. Today we address difficult cases: the patient who cannot undergo surgery, the tumor that recurs despite our best efforts, and the adenoid cystic carcinoma that metastasizes to the lungs years after we thought we had won. We will also cover a rapidly evolving area – biomarker-driven systemic therapy. This is where salivary gland oncology is changing fastest, and the board examiners know it.]]></itunes:summary><itunes:duration>2261</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E36: Salivary Gland III Perineural Invasion and Named Nerve Strategy</title><link>https://www.spreaker.com/episode/h-n-e36-salivary-gland-iii-perineural-invasion-and-named-nerve-strategy--70010740</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 36: Salivary Gland Three — Perineural Invasion and Named Nerve Strategy. Perineural invasion is the defining challenge of salivary gland radiation oncology. It is why adenoid cystic carcinoma behaves differently from mucoepidermoid. This is why some tumors recur at the skull base years after treatment. And it is absolutely a topic you will face on oral boards. Today, we build the complete framework for understanding, imaging, and treating perineural disease. By the end of this episode, you will be able to distinguish histologic P-N-I from clinical perineural tumor spread, trace the major nerve highways to their skull base foramina, and deliver a board-safe statement about when and how to extend your C-T-V tothe skull base.]]></description><guid isPermaLink="false">0e45d8e6-0779-4685-8760-87051c1cc9dc</guid><pubDate>Thu, 12 Feb 2026 08:27:06 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/70010740/255230f5_b1c6_2543_2316_4efe61f0c423.mp3" length="25140381" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1U9TZlFkjcmDXKZLGKHPhY/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 36: Salivary Gland Three — Perineural Invasion and Named Nerve Strategy. Perineural invasion is the defining challenge of salivary gland radiation oncology. It is why adenoid...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 36: Salivary Gland Three — Perineural Invasion and Named Nerve Strategy. Perineural invasion is the defining challenge of salivary gland radiation oncology. It is why adenoid cystic carcinoma behaves differently from mucoepidermoid. This is why some tumors recur at the skull base years after treatment. And it is absolutely a topic you will face on oral boards. Today, we build the complete framework for understanding, imaging, and treating perineural disease. By the end of this episode, you will be able to distinguish histologic P-N-I from clinical perineural tumor spread, trace the major nerve highways to their skull base foramina, and deliver a board-safe statement about when and how to extend your C-T-V tothe skull base.]]></itunes:summary><itunes:duration>1572</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E35: Salivary Gland II — Adjuvant RT Triggers and Planning</title><link>https://www.spreaker.com/episode/h-n-e35-salivary-gland-ii-adjuvant-rt-triggers-and-planning--70010741</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 35: Salivary Gland Two — Adjuvant RT Triggers and Planning. In Episode 34, we built the salivary gland paradigm: histology leads, surgery is primary, and adjuvant decisions are driven by risk factors that salivary tumors love to hide—especially perineural invasion and margin risk. Today is the bridge episode. We take our Episode 34 case back from the operating room and turn it into a board-safe, execution-ready postoperative plan. This is high-yield material for oral boards, where you will absolutely be asked to justify your P-O-R-T indications, define your target volumes, and defend your dose levels. By the end of this episode, you will be able to recite the complete P-O-R-T indication list with evidence citations, define the anatomic boundaries of the parotid surgical bed C-T-V, and explain exactly when and how to track the facial nerve in your target volumes.]]></description><guid isPermaLink="false">b9f57c86-44fb-4153-a4cc-7c3cc0e9e045</guid><pubDate>Thu, 12 Feb 2026 08:25:46 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/70010741/fc47b054_6e1f_5bbe_06a2_94ca94174045.mp3" length="26761645" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/20gWRP6DUOSHfgULx2V8a7/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 35: Salivary Gland Two — Adjuvant RT Triggers and Planning. In Episode 34, we built the salivary gland paradigm: histology leads, surgery is primary, and adjuvant decisions...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 35: Salivary Gland Two — Adjuvant RT Triggers and Planning. In Episode 34, we built the salivary gland paradigm: histology leads, surgery is primary, and adjuvant decisions are driven by risk factors that salivary tumors love to hide—especially perineural invasion and margin risk. Today is the bridge episode. We take our Episode 34 case back from the operating room and turn it into a board-safe, execution-ready postoperative plan. This is high-yield material for oral boards, where you will absolutely be asked to justify your P-O-R-T indications, define your target volumes, and defend your dose levels. By the end of this episode, you will be able to recite the complete P-O-R-T indication list with evidence citations, define the anatomic boundaries of the parotid surgical bed C-T-V, and explain exactly when and how to track the facial nerve in your target volumes.]]></itunes:summary><itunes:duration>1673</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E34: Salivary Gland I — Histology-Driven Biology and the Surgical Paradigm</title><link>https://www.spreaker.com/episode/h-n-e34-salivary-gland-i-histology-driven-biology-and-the-surgical-paradigm--70009263</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 34: Salivary Gland One — Histology-Driven Biology and the Surgical Paradigm. This episode launches our salivary gland block, and I want to be direct: salivary gland cancers are a board favorite because they force you to think differently. Unlike mucosal squamous cell carcinomas, where HPV status and TNM staging drive almost everything, salivary tumors require you to lead with histology. The histologic subtype tells you about local aggressiveness, perineural invasion risk, nodal behavior, and distant metastasis timing. Get the histology wrong, and your entire management framework collapses. Today, we establish the foundational paradigm: anatomy, histology diversity, why surgery is primary, how the facial nerve changes surgical decision-making, and an overview of when postoperative R-T enters the picture. This episode is high-yield for both written boards and oral examinations, where you will absolutely see a parotid mass with facial weakness and need to walk through the management algorithm.]]></description><guid isPermaLink="false">085d2cbb-c57c-4954-ace1-13b5ecb154e6</guid><pubDate>Thu, 12 Feb 2026 08:24:20 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/70009263/20f388d6_af4a_32e0_e9cb_ee1c33cd7044.mp3" length="31253035" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 34: Salivary Gland One — Histology-Driven Biology and the Surgical Paradigm. This episode launches our salivary gland block, and I want to be direct: salivary gland cancers...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 34: Salivary Gland One — Histology-Driven Biology and the Surgical Paradigm. This episode launches our salivary gland block, and I want to be direct: salivary gland cancers are a board favorite because they force you to think differently. Unlike mucosal squamous cell carcinomas, where HPV status and TNM staging drive almost everything, salivary tumors require you to lead with histology. The histologic subtype tells you about local aggressiveness, perineural invasion risk, nodal behavior, and distant metastasis timing. Get the histology wrong, and your entire management framework collapses. Today, we establish the foundational paradigm: anatomy, histology diversity, why surgery is primary, how the facial nerve changes surgical decision-making, and an overview of when postoperative R-T enters the picture. This episode is high-yield for both written boards and oral examinations, where you will absolutely see a parotid mass with facial weakness and need to walk through the management algorithm.]]></itunes:summary><itunes:duration>1954</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E33: Hypopharynx Integration Decision Points and Surveillance</title><link>https://www.spreaker.com/episode/h-n-e33-hypopharynx-integration-decision-points-and-surveillance--69782769</link><description><![CDATA[This is Episode 33: Hypopharynx Integration Decision Points and Surveillance. Episode 31 covered the biology, including the worst-actor paradigm, prognosis, and the four defaults. Episodes 32 and 32b focused on planning: contouring, extension, and coverage. Now, we address the integration question: Who receives which treatment, and what does success look like? This episode explores decision-making. We'll discuss organ preservation, when to prioritize surgery, response assessment, salvage expectations, and the role of early palliative care.]]></description><guid isPermaLink="false">83ec0bdd-a6b2-4fc4-9783-731c65481e2c</guid><pubDate>Wed, 04 Feb 2026 08:38:33 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69782769/d310625f_55be_8e6b_ec3f_e3c0bfecb8df.mp3" length="29798537" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6LFKO7fvf2VHOE5mo5xzz6/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 33: Hypopharynx Integration Decision Points and Surveillance. Episode 31 covered the biology, including the worst-actor paradigm, prognosis, and the four defaults. Episodes 32 and 32b focused on planning: contouring, extension, and...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 33: Hypopharynx Integration Decision Points and Surveillance. Episode 31 covered the biology, including the worst-actor paradigm, prognosis, and the four defaults. Episodes 32 and 32b focused on planning: contouring, extension, and coverage. Now, we address the integration question: Who receives which treatment, and what does success look like? This episode explores decision-making. We'll discuss organ preservation, when to prioritize surgery, response assessment, salvage expectations, and the role of early palliative care.]]></itunes:summary><itunes:duration>1863</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E32B: Hypopharynx Planning Workshop</title><link>https://www.spreaker.com/episode/h-n-e32b-hypopharynx-planning-workshop--69782772</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 32b: Hypopharynx Planning Workshop. Episode 32 gave you the rules, the four defaults, the nodal template, the inferior extent ladder, and the OAR priorities. Today, we build muscle memory. We're at the contouring workstation. Two complete cases. No new teaching pure application and narrated decision-making. Here's what I need from you: every time I state a default, say it back in your head. By the end of this workshop, those four defaults should fire automatically whenever you see a hypopharynx case.]]></description><guid isPermaLink="false">71b5b725-5bbf-4d39-9fa4-73b72aca4aed</guid><pubDate>Wed, 04 Feb 2026 08:36:28 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69782772/055640a9_3ae0_6899_3189_88f6bcbd23ad.mp3" length="32206817" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4IsiPou2RaLZ19k3qFIK3L/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 32b: Hypopharynx Planning Workshop. Episode 32 gave you the rules, the four defaults, the nodal template, the inferior extent ladder, and the OAR priorities. Today, we build...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 32b: Hypopharynx Planning Workshop. Episode 32 gave you the rules, the four defaults, the nodal template, the inferior extent ladder, and the OAR priorities. Today, we build muscle memory. We're at the contouring workstation. Two complete cases. No new teaching pure application and narrated decision-making. Here's what I need from you: every time I state a default, say it back in your head. By the end of this workshop, those four defaults should fire automatically whenever you see a hypopharynx case.]]></itunes:summary><itunes:duration>2013</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E32: Hypopharynx II Treatment Planning and Cervical Esophagus Extension.</title><link>https://www.spreaker.com/episode/h-n-e32-hypopharynx-ii-treatment-planning-and-cervical-esophagus-extension--69782771</link><description><![CDATA[In Episode 31, we established the foundational paradigm for hypopharyngeal cancer, the worst-actor subsite in head and neck oncology. We defined four defaults that govern our approach to these cases: Default one: retropharyngeal nodes on. Default two: bilateral neck on. Default three: inferior extent on. Default four: prognosis is brutal, plan accordingly. Today, we translate those defaults into actual treatment contours. This episode focuses on operationalizing principles into treatment plans that you can defend on oral boards and execute at the workstation.]]></description><guid isPermaLink="false">6f429d38-b671-4257-aab2-d8ac379786ab</guid><pubDate>Wed, 04 Feb 2026 08:34:41 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69782771/4b9ed590_315a_2d9b_dea2_1674ba7e70c4.mp3" length="31409351" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0KttLRnMXnJ32qKndpllgG/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In Episode 31, we established the foundational paradigm for hypopharyngeal cancer, the worst-actor subsite in head and neck oncology. We defined four defaults that govern our approach to these cases: Default one: retropharyngeal nodes on. Default two:...</itunes:subtitle><itunes:summary><![CDATA[In Episode 31, we established the foundational paradigm for hypopharyngeal cancer, the worst-actor subsite in head and neck oncology. We defined four defaults that govern our approach to these cases: Default one: retropharyngeal nodes on. Default two: bilateral neck on. Default three: inferior extent on. Default four: prognosis is brutal, plan accordingly. Today, we translate those defaults into actual treatment contours. This episode focuses on operationalizing principles into treatment plans that you can defend on oral boards and execute at the workstation.]]></itunes:summary><itunes:duration>1964</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E31: Hypopharynx I Anatomy, Prognosis, and the Worst-Actor Paradigm</title><link>https://www.spreaker.com/episode/h-n-e31-hypopharynx-i-anatomy-prognosis-and-the-worst-actor-paradigm--69782770</link><description><![CDATA[This is Episode Thirty-One: Hypopharynx One — Anatomy, Prognosis, and the Worst-Actor Paradigm. Today we tackle the subsite that earns its reputation as the worst actor in head and neck oncology. Hypopharyngeal cancer presents late, spreads early, and hides submucosally—which means your default choices must be aggressive from the start. This episode is foundational. We will not contour a single structure today. What we will do is hard-wire the four defaults that will drive every planning and management decision in Episodes Thirty-Two and Thirty-Three.]]></description><guid isPermaLink="false">e18068f3-ed62-4626-a098-c671c1a9565b</guid><pubDate>Wed, 04 Feb 2026 08:32:37 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69782770/c9f63f19_ad4b_d092_ec7d_0d3ef5173c5b.mp3" length="33747833" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6LEe4HCh0mJj2dTVFHTIqK/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode Thirty-One: Hypopharynx One — Anatomy, Prognosis, and the Worst-Actor Paradigm. Today we tackle the subsite that earns its reputation as the worst actor in head and neck oncology. Hypopharyngeal cancer presents late, spreads early, and...</itunes:subtitle><itunes:summary><![CDATA[This is Episode Thirty-One: Hypopharynx One — Anatomy, Prognosis, and the Worst-Actor Paradigm. Today we tackle the subsite that earns its reputation as the worst actor in head and neck oncology. Hypopharyngeal cancer presents late, spreads early, and hides submucosally—which means your default choices must be aggressive from the start. This episode is foundational. We will not contour a single structure today. What we will do is hard-wire the four defaults that will drive every planning and management decision in Episodes Thirty-Two and Thirty-Three.]]></itunes:summary><itunes:duration>2110</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E30: Larynx Capstone — Mock Oral Board Review</title><link>https://www.spreaker.com/episode/h-n-e30-larynx-capstone-mock-oral-board-review--69712128</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 30: Larynx Capstone – Mock Oral Board Review. Today we simulate the oral boards exam in four clinical blocks. Each block features a case that escalates through workup, staging, treatment selection, planning priorities, and outcomes. We'll close each block with a twist testing a key decision pivot. Treat this like a live exam. After every question, you will hear: "Pause for listener to formulate response." Use that pause. Then compare your answer to the model response.]]></description><guid isPermaLink="false">9fb93695-4c38-4679-8366-bdfce30329b1</guid><pubDate>Sat, 31 Jan 2026 20:40:11 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69712128/e323b41d_807b_1750_b664_59c0db77f293.mp3" length="25266605" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2v0UnkHQ9npUT9z3zEQpxn/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 30: Larynx Capstone – Mock Oral Board Review. Today we simulate the oral boards exam in four clinical blocks. Each block features a case that escalates through workup,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 30: Larynx Capstone – Mock Oral Board Review. Today we simulate the oral boards exam in four clinical blocks. Each block features a case that escalates through workup, staging, treatment selection, planning priorities, and outcomes. We'll close each block with a twist testing a key decision pivot. Treat this like a live exam. After every question, you will hear: "Pause for listener to formulate response." Use that pause. Then compare your answer to the model response.]]></itunes:summary><itunes:duration>1580</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E29: Advanced Larynx — T4a and the Unpreservable.</title><link>https://www.spreaker.com/episode/h-n-e29-advanced-larynx-t4a-and-the-unpreservable--69586669</link><description><![CDATA[This episode, number 29, focuses on Advanced Larynx T4a and the Unpreservable. Building upon Episode 28's discussion of organ preservation, we explore instances where such preservation is not the optimal course of action. Specifically, we examine how to identify patients for whom maintaining the larynx is either impractical or detrimental. Given the natural inclination to offer preservation, this episode aims to equip listeners with the knowledge to counsel patients appropriately, whether advocating for preservation when suitable or recommending upfront laryngectomy when it is the more beneficial pathway. By the conclusion of this episode, listeners will possess a framework for recognizing the "unpreservable" patient and understanding the limitations of current landmark trials when applied to bulky T4a disease.]]></description><guid isPermaLink="false">afb3141b-494c-4aa6-8470-d6c01f85822b</guid><pubDate>Mon, 26 Jan 2026 03:08:46 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69586669/3be4ba26_8ba9_390c_4c63_c80208c5681e.mp3" length="30260799" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2McUfuk3I1bo6NdZrh5Mq4/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This episode, number 29, focuses on Advanced Larynx T4a and the Unpreservable. Building upon Episode 28's discussion of organ preservation, we explore instances where such preservation is not the optimal course of action. Specifically, we examine how...</itunes:subtitle><itunes:summary><![CDATA[This episode, number 29, focuses on Advanced Larynx T4a and the Unpreservable. Building upon Episode 28's discussion of organ preservation, we explore instances where such preservation is not the optimal course of action. Specifically, we examine how to identify patients for whom maintaining the larynx is either impractical or detrimental. Given the natural inclination to offer preservation, this episode aims to equip listeners with the knowledge to counsel patients appropriately, whether advocating for preservation when suitable or recommending upfront laryngectomy when it is the more beneficial pathway. By the conclusion of this episode, listeners will possess a framework for recognizing the "unpreservable" patient and understanding the limitations of current landmark trials when applied to bulky T4a disease.]]></itunes:summary><itunes:duration>1892</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E28: Organ Preservation The Landmark Trials</title><link>https://www.spreaker.com/episode/h-n-e28-organ-preservation-the-landmark-trials--69586668</link><description><![CDATA[This episode, number 28, explores "Organ Preservation: The Landmark Trials." Prior to 1991, the standard treatment for advanced laryngeal cancer involved total laryngectomy and radiation, which, while ensuring patient survival, resulted in the loss of natural voice, the inability to breathe through the nose and mouth, and a permanent stoma. A pivotal question emerged: could equivalent survival rates be achieved while preserving the larynx? Landmark trials provided an affirmative answer, emphasizing the importance of appropriate patient selection and treatment strategies. However, long-term follow-up studies revealed concerning late toxicities associated with larynx-preserving treatments, which may impact survival in complex, still-unresolved ways. In this episode, we will analyze the VA Larynx, RTOG 91-11, and GORTEC 2000-01 trials, providing insights for both board preparation and clinical practice. By the conclusion, listeners will not only comprehend the trials' findings but also learn how to apply them effectively to real-world patient care.]]></description><guid isPermaLink="false">809f2026-f046-4f7a-a352-7482b0afb3fe</guid><pubDate>Mon, 26 Jan 2026 03:07:25 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69586668/a1736766_1348_b3d4_986a_5a0bc41744a7.mp3" length="30154638" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6RgDp4m9nloCvgUlwOJ3Sb/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This episode, number 28, explores "Organ Preservation: The Landmark Trials." Prior to 1991, the standard treatment for advanced laryngeal cancer involved total laryngectomy and radiation, which, while ensuring patient survival, resulted in the loss of...</itunes:subtitle><itunes:summary><![CDATA[This episode, number 28, explores "Organ Preservation: The Landmark Trials." Prior to 1991, the standard treatment for advanced laryngeal cancer involved total laryngectomy and radiation, which, while ensuring patient survival, resulted in the loss of natural voice, the inability to breathe through the nose and mouth, and a permanent stoma. A pivotal question emerged: could equivalent survival rates be achieved while preserving the larynx? Landmark trials provided an affirmative answer, emphasizing the importance of appropriate patient selection and treatment strategies. However, long-term follow-up studies revealed concerning late toxicities associated with larynx-preserving treatments, which may impact survival in complex, still-unresolved ways. In this episode, we will analyze the VA Larynx, RTOG 91-11, and GORTEC 2000-01 trials, providing insights for both board preparation and clinical practice. By the conclusion, listeners will not only comprehend the trials' findings but also learn how to apply them effectively to real-world patient care.]]></itunes:summary><itunes:duration>1885</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E27b: Early Larynx Planning Workshop</title><link>https://www.spreaker.com/episode/h-n-e27b-early-larynx-planning-workshop--69586670</link><description><![CDATA[This is Episode 27b: Early Larynx Planning Workshop. In Episode 27, we addressed the fundamental aspects, including the radiocurability of early glottic cancer, the standard fractionation of 2.25 Gy/fx, and the rationale for neck sparing due to a nodal risk of less than 5%. This session focuses on the practical application—transferring this knowledge to the planning stage to develop a defensible and clinically safe treatment plan. The reality is that early glottic failures are often preventable. They are rarely due to incorrect dose selection. Instead, they are often caused by setup errors, inadequate anterior commissure coverage, insufficient flash, or unintended undercoverage resulting from the pursuit of homogeneity. By the conclusion of this workshop, participants will be able to simulate patients accurately, construct classic opposed-lateral plans, elucidate wedge/bolus trade-offs, and clearly articulate the appropriateness of IMRT and the distinctions between proven and unproven techniques.]]></description><guid isPermaLink="false">5f0295d1-fb9a-4097-877e-607c20fe2525</guid><pubDate>Mon, 26 Jan 2026 03:05:24 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69586670/f7efa95c_4700_f29d_7c38_a7356c2d5eb2.mp3" length="31125139" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5ewnjknreaS66S9BQROAGQ/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 27b: Early Larynx Planning Workshop. In Episode 27, we addressed the fundamental aspects, including the radiocurability of early glottic cancer, the standard fractionation of 2.25 Gy/fx, and the rationale for neck sparing due to a...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 27b: Early Larynx Planning Workshop. In Episode 27, we addressed the fundamental aspects, including the radiocurability of early glottic cancer, the standard fractionation of 2.25 Gy/fx, and the rationale for neck sparing due to a nodal risk of less than 5%. This session focuses on the practical application—transferring this knowledge to the planning stage to develop a defensible and clinically safe treatment plan. The reality is that early glottic failures are often preventable. They are rarely due to incorrect dose selection. Instead, they are often caused by setup errors, inadequate anterior commissure coverage, insufficient flash, or unintended undercoverage resulting from the pursuit of homogeneity. By the conclusion of this workshop, participants will be able to simulate patients accurately, construct classic opposed-lateral plans, elucidate wedge/bolus trade-offs, and clearly articulate the appropriateness of IMRT and the distinctions between proven and unproven techniques.]]></itunes:summary><itunes:duration>1946</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E27: Early Glottic Cancer Fields, Fractionation, and Voice Preservation</title><link>https://www.spreaker.com/episode/h-n-e27-early-glottic-cancer-fields-fractionation-and-voice-preservation--69586671</link><description><![CDATA[This is Episode 27: Early Glottic Cancer Fields, Fractionation, and Voice Preservation. Early glottic cancer represents the prototype of a radiation-curable malignancy. It is one of the few oncological sites where we routinely achieve patient cures through radiation therapy alone, preserving the organ while attaining functional outcomes that surgery often fails to match. For T1 glottic cancer, 5-year local control rates exceed 90%. For T2 disease, we still achieve 70-80% local control with radiation alone, and salvage laryngectomy remains an option for those who experience recurrence. The key to differentiating successful residents from their less-accomplished peers lies in understanding the rationale behind specific fractionation schemes, the reasons for neck sparing, and the methodology for designing fields that adequately cover the disease while avoiding underdosing the anterior commissure or overdosing posterior structures. Today, we will comprehensively address all these aspects. Upon completion of this episode, listeners will be equipped to accurately stage early glottic cancer, prescribe optimal fractionation, design classic opposed lateral fields, and counsel patients regarding anticipated voice outcomes.]]></description><guid isPermaLink="false">3625bd6f-896b-455f-81bf-21ea12724797</guid><pubDate>Mon, 26 Jan 2026 03:03:15 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69586671/1aaf3609_b8a4_c1f8_c24b_33058032d081.mp3" length="32180904" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1c9hGC11uCr3M19xJUzNZw/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 27: Early Glottic Cancer Fields, Fractionation, and Voice Preservation. Early glottic cancer represents the prototype of a radiation-curable malignancy. It is one of the few oncological sites where we routinely achieve patient cures...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 27: Early Glottic Cancer Fields, Fractionation, and Voice Preservation. Early glottic cancer represents the prototype of a radiation-curable malignancy. It is one of the few oncological sites where we routinely achieve patient cures through radiation therapy alone, preserving the organ while attaining functional outcomes that surgery often fails to match. For T1 glottic cancer, 5-year local control rates exceed 90%. For T2 disease, we still achieve 70-80% local control with radiation alone, and salvage laryngectomy remains an option for those who experience recurrence. The key to differentiating successful residents from their less-accomplished peers lies in understanding the rationale behind specific fractionation schemes, the reasons for neck sparing, and the methodology for designing fields that adequately cover the disease while avoiding underdosing the anterior commissure or overdosing posterior structures. Today, we will comprehensively address all these aspects. Upon completion of this episode, listeners will be equipped to accurately stage early glottic cancer, prescribe optimal fractionation, design classic opposed lateral fields, and counsel patients regarding anticipated voice outcomes.]]></itunes:summary><itunes:duration>2012</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E26: Larynx I Anatomy, Staging, and the Organ Preservation Philosophy</title><link>https://www.spreaker.com/episode/h-n-e26-larynx-i-anatomy-staging-and-the-organ-preservation-philosophy--69586672</link><description><![CDATA[This is Episode 26: Larynx I- Anatomy, Staging, and the Organ Preservation Philosophy. The larynx holds a unique position in head and neck oncology. It is the one subsite where we routinely achieve cancer cures while preserving organ function. In early glottic cancer, radiation therapy achieves local control rates exceeding 90 percent with excellent voice outcomes. In advanced disease, concurrent chemoradiation can preserve the larynx in approximately 80 percent of patients. However, making sound treatment decisions – whether to use radiation alone, add chemotherapy, or recommend upfront surgery – requires a deep understanding of laryngeal anatomy, a skill that distinguishes proficient residents from their less experienced counterparts. Today, we will establish this foundational knowledge. By the conclusion of this episode, listeners will be able to visualize the larynx in three dimensions, accurately stage any laryngeal cancer, explain the differential behavior of glottic and supraglottic cancers, and articulate the organ preservation philosophy that underpins contemporary management strategies.]]></description><guid isPermaLink="false">11b3442a-7ed2-4e98-83c9-9e347ed432b5</guid><pubDate>Mon, 26 Jan 2026 03:01:21 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69586672/44b67e9b_dbe4_d8f8_356a_394d8b090e39.mp3" length="24317420" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1mh340RTHLI78RPOf6g4lQ/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 26: Larynx I- Anatomy, Staging, and the Organ Preservation Philosophy. The larynx holds a unique position in head and neck oncology. It is the one subsite where we routinely achieve cancer cures while preserving organ function. In...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 26: Larynx I- Anatomy, Staging, and the Organ Preservation Philosophy. The larynx holds a unique position in head and neck oncology. It is the one subsite where we routinely achieve cancer cures while preserving organ function. In early glottic cancer, radiation therapy achieves local control rates exceeding 90 percent with excellent voice outcomes. In advanced disease, concurrent chemoradiation can preserve the larynx in approximately 80 percent of patients. However, making sound treatment decisions – whether to use radiation alone, add chemotherapy, or recommend upfront surgery – requires a deep understanding of laryngeal anatomy, a skill that distinguishes proficient residents from their less experienced counterparts. Today, we will establish this foundational knowledge. By the conclusion of this episode, listeners will be able to visualize the larynx in three dimensions, accurately stage any laryngeal cancer, explain the differential behavior of glottic and supraglottic cancers, and articulate the organ preservation philosophy that underpins contemporary management strategies.]]></itunes:summary><itunes:duration>1520</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E25: Nasopharynx Capstone Mock Oral Boards</title><link>https://www.spreaker.com/episode/h-n-e25-nasopharynx-capstone-mock-oral-boards--69576792</link><description><![CDATA[This is Episode 25: Nasopharynx Capstone – Mock Oral Boards. Today, we will simulate the oral board examination through four clinical blocks. Each block presents a case that progresses from workup to staging, treatment selection, planning priorities, and outcomes. Each block concludes with a twist designed to test a key decision point. Please treat this as a live examination.]]></description><guid isPermaLink="false">a706fd86-10c3-41b1-84b7-f57a546dea8f</guid><pubDate>Sun, 25 Jan 2026 02:30:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69576792/61839f91_463d_b1be_5df9_bce1540d5d53.mp3" length="18520326" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6tMrwgx7ytkHPWiKEBOFEN/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 25: Nasopharynx Capstone – Mock Oral Boards. Today, we will simulate the oral board examination through four clinical blocks. Each block presents a case that progresses from workup to staging, treatment selection, planning priorities,...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 25: Nasopharynx Capstone – Mock Oral Boards. Today, we will simulate the oral board examination through four clinical blocks. Each block presents a case that progresses from workup to staging, treatment selection, planning priorities, and outcomes. Each block concludes with a twist designed to test a key decision point. Please treat this as a live examination.]]></itunes:summary><itunes:duration>1158</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E24B: The Nasopharynx Planning Workshop, Focuses on skull base abutment cases</title><link>https://www.spreaker.com/episode/h-n-e24b-the-nasopharynx-planning-workshop-focuses-on-skull-base-abutment-cases--69576795</link><description><![CDATA[This is Episode 24b: The Nasopharynx Planning Workshop, which focuses on skull base abutment cases. In the preceding episodes, we established the clinical framework for nasopharyngeal carcinoma, encompassing anatomy, staging, EBV biology, systemic therapy sequencing, response assessment, and salvage strategies. We now transition to the planning workstation, where the decisions made within the next 45 minutes can determine whether a patient experiences acceptable function or suffers catastrophic late toxicity.]]></description><guid isPermaLink="false">eadf3791-1f2e-47e5-89c9-ced95d4091e0</guid><pubDate>Sun, 25 Jan 2026 02:27:19 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69576795/3243d561_89ac_0953_7c82_e155599fde15.mp3" length="23534582" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4KJP4QaJzUdsubr1CfncCy/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 24b: The Nasopharynx Planning Workshop, which focuses on skull base abutment cases. In the preceding episodes, we established the clinical framework for nasopharyngeal carcinoma, encompassing anatomy, staging, EBV biology, systemic...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 24b: The Nasopharynx Planning Workshop, which focuses on skull base abutment cases. In the preceding episodes, we established the clinical framework for nasopharyngeal carcinoma, encompassing anatomy, staging, EBV biology, systemic therapy sequencing, response assessment, and salvage strategies. We now transition to the planning workstation, where the decisions made within the next 45 minutes can determine whether a patient experiences acceptable function or suffers catastrophic late toxicity.]]></itunes:summary><itunes:duration>1471</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E24: Nasopharynx IV Response Assessment and Salvage</title><link>https://www.spreaker.com/episode/h-n-e24-nasopharynx-iv-response-assessment-and-salvage--69576794</link><description><![CDATA[This is Episode 24: Nasopharynx IV Response Assessment and Salvage. Building upon the previous two episodes, we have established that nasopharyngeal carcinoma is a radiation-driven disease. We have reviewed the anatomy, EBV biology, staging, and evidence supporting concurrent chemoradiation, with or without induction. Now, we address the critical question patients will invariably pose: "Did it work?" More importantly, we will explore the appropriate course of action when the answer is negative. This episode delves into high-stakes scenarios. Recurrent NPC following definitive chemoradiation presents one of the most complex decision points in head and neck oncology. The available options include surgery, re-irradiation, or systemic therapy; however, an incorrect decision can have catastrophic consequences. Treatment-related mortality in the re-irradiation setting can exceed 10%. Risks such as carotid blowout syndrome, temporal lobe necrosis, and nasopharyngeal hemorrhage are not merely theoretical concerns but represent the daily realities of managing recurrent disease. By the conclusion of this episode, you will be equipped to assess response, determine appropriate intervention strategies, and counsel patients through what may be the most critical treatment decision of their lives.]]></description><guid isPermaLink="false">94c2222d-68f4-4acd-8de5-9b3b3bab2a59</guid><pubDate>Sun, 25 Jan 2026 02:23:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69576794/70054ddf_7d54_4723_d85c_c4e76213bd5c.mp3" length="22719980" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4PoYA3rdX9KEpeuZrBXvp6/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 24: Nasopharynx IV Response Assessment and Salvage. Building upon the previous two episodes, we have established that nasopharyngeal carcinoma is a radiation-driven disease. We have reviewed the anatomy, EBV biology, staging, and...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 24: Nasopharynx IV Response Assessment and Salvage. Building upon the previous two episodes, we have established that nasopharyngeal carcinoma is a radiation-driven disease. We have reviewed the anatomy, EBV biology, staging, and evidence supporting concurrent chemoradiation, with or without induction. Now, we address the critical question patients will invariably pose: "Did it work?" More importantly, we will explore the appropriate course of action when the answer is negative. This episode delves into high-stakes scenarios. Recurrent NPC following definitive chemoradiation presents one of the most complex decision points in head and neck oncology. The available options include surgery, re-irradiation, or systemic therapy; however, an incorrect decision can have catastrophic consequences. Treatment-related mortality in the re-irradiation setting can exceed 10%. Risks such as carotid blowout syndrome, temporal lobe necrosis, and nasopharyngeal hemorrhage are not merely theoretical concerns but represent the daily realities of managing recurrent disease. By the conclusion of this episode, you will be equipped to assess response, determine appropriate intervention strategies, and counsel patients through what may be the most critical treatment decision of their lives.]]></itunes:summary><itunes:duration>1420</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E23: Nasopharynx III Induction and Concurrent Systemic Therapy</title><link>https://www.spreaker.com/episode/h-n-e23-nasopharynx-iii-induction-and-concurrent-systemic-therapy--69576630</link><description><![CDATA[This episode, number 23, focuses on Nasopharynx III Induction and Concurrent Systemic Therapy. Building on Episode 22, where we established NPC as a radiation-driven disease with unique anatomy and EBV biology, and Episode 22b, where we covered target volumes, we now delve into the systemic therapy backbone, the chemotherapy decisions that determine patient outcomes. This high-yield episode highlights the unique aspects of NPC systemic therapy compared to other head and neck cancers. Specifically, it explores why induction studies that failed in the oropharynx and larynx actually work in NPC, offering crucial insights for board exams.]]></description><guid isPermaLink="false">d555a414-c1e4-4c1e-9f3f-c6b45ad92ec7</guid><pubDate>Sun, 25 Jan 2026 02:15:50 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69576630/ef6200a8_34ae_64b5_4f71_dbce3dee82af.mp3" length="26834370" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This episode, number 23, focuses on Nasopharynx III Induction and Concurrent Systemic Therapy. Building on Episode 22, where we established NPC as a radiation-driven disease with unique anatomy and EBV biology, and Episode 22b, where we covered target...</itunes:subtitle><itunes:summary><![CDATA[This episode, number 23, focuses on Nasopharynx III Induction and Concurrent Systemic Therapy. Building on Episode 22, where we established NPC as a radiation-driven disease with unique anatomy and EBV biology, and Episode 22b, where we covered target volumes, we now delve into the systemic therapy backbone, the chemotherapy decisions that determine patient outcomes. This high-yield episode highlights the unique aspects of NPC systemic therapy compared to other head and neck cancers. Specifically, it explores why induction studies that failed in the oropharynx and larynx actually work in NPC, offering crucial insights for board exams.]]></itunes:summary><itunes:duration>1678</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E22B:Nasopharynx II Target Volume Masterclass</title><link>https://www.spreaker.com/episode/h-n-e22b-nasopharynx-ii-target-volume-masterclass--69543933</link><description><![CDATA[In Episode 22, we framed nasopharyngeal carcinoma as a radiation-driven disease with distinct anatomy, EBV association, and AJCC 8 edition staging built around skull base landmarks. Now we do the part that oral boards loves: designing the plan.]]></description><guid isPermaLink="false">44df0d5c-17ce-4f13-bbdf-6cf7a7e69b1e</guid><pubDate>Thu, 22 Jan 2026 08:32:27 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69543933/c8d53e3a_5d96_ea41_dfe0_f582c97c92d1.mp3" length="28353234" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1AYR8d2qrHNzztL5vayleN/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In Episode 22, we framed nasopharyngeal carcinoma as a radiation-driven disease with distinct anatomy, EBV association, and AJCC 8 edition staging built around skull base landmarks. Now we do the part that oral boards loves: designing the plan.</itunes:subtitle><itunes:summary><![CDATA[In Episode 22, we framed nasopharyngeal carcinoma as a radiation-driven disease with distinct anatomy, EBV association, and AJCC 8 edition staging built around skull base landmarks. Now we do the part that oral boards loves: designing the plan.]]></itunes:summary><itunes:duration>1773</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E22: Nasopharynx I — Anatomy, EBV Biology, and the Definitive RT Paradigm</title><link>https://www.spreaker.com/episode/h-n-e22-nasopharynx-i-anatomy-ebv-biology-and-the-definitive-rt-paradigm--69543934</link><description><![CDATA[This is Episode 22: Nasopharynx I Anatomy, E. B. V. Biology, and the Definitive R. T. Paradigm. Nasopharyngeal carcinoma is a board-favorite because it behaves unlike the rest of the head and neck. It is a radiation-first disease with skull base anatomy, retropharyngeal nodes as default, and a biomarker you are expected to talk about fluently: plasma E. B. V. D. N. A.]]></description><guid isPermaLink="false">5d39cf5c-11b0-4c5a-a70e-bb9278ae767a</guid><pubDate>Thu, 22 Jan 2026 08:30:41 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69543934/25f56ace_ca6a_c489_2177_7a82bf81db82.mp3" length="25675369" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4JBUVr2gvlpXo20sANfBB8/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 22: Nasopharynx I Anatomy, E. B. V. Biology, and the Definitive R. T. Paradigm. Nasopharyngeal carcinoma is a board-favorite because it behaves unlike the rest of the head and neck. It is a radiation-first disease with skull base...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 22: Nasopharynx I Anatomy, E. B. V. Biology, and the Definitive R. T. Paradigm. Nasopharyngeal carcinoma is a board-favorite because it behaves unlike the rest of the head and neck. It is a radiation-first disease with skull base anatomy, retropharyngeal nodes as default, and a biomarker you are expected to talk about fluently: plasma E. B. V. D. N. A.]]></itunes:summary><itunes:duration>1605</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E21:Oropharynx Capstone Mock Oral Boards</title><link>https://www.spreaker.com/episode/h-n-e21-oropharynx-capstone-mock-oral-boards--69527385</link><description><![CDATA[This is Episode 21: Oropharynx Capstone Mock Oral Boards. Today, we simulate the oral boards exam in five clinical blocks. Each block features a longitudinal case that escalates through workup, staging, treatment selection, planning priorities, and outcomes. Then we close each block with a shorter twist that tests a key decision pivot. Treat this like a live exam. After every question, you will hear: "Pause for listener to formulate response." Use that pause. Then compare your answer to the model response.]]></description><guid isPermaLink="false">52801efe-654e-43be-a0d9-83d51d8adce6</guid><pubDate>Wed, 21 Jan 2026 03:48:32 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69527385/6f399e56_3d7d_efdb_8f25_44b28c3bd3ba.mp3" length="28956767" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1YzGAYjeFdSjkHZtHgOPSw/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 21: Oropharynx Capstone Mock Oral Boards. Today, we simulate the oral boards exam in five clinical blocks. Each block features a longitudinal case that escalates through workup, staging, treatment selection, planning priorities, and...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 21: Oropharynx Capstone Mock Oral Boards. Today, we simulate the oral boards exam in five clinical blocks. Each block features a longitudinal case that escalates through workup, staging, treatment selection, planning priorities, and outcomes. Then we close each block with a shorter twist that tests a key decision pivot. Treat this like a live exam. After every question, you will hear: "Pause for listener to formulate response." Use that pause. Then compare your answer to the model response.]]></itunes:summary><itunes:duration>1810</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E20:Functional Outcomes &amp; Survivorship in Oropharyngeal Cancer</title><link>https://www.spreaker.com/episode/h-n-e20-functional-outcomes-survivorship-in-oropharyngeal-cancer--69490328</link><description><![CDATA[This is Episode 20: Functional Outcomes and Survivorship in Oropharyngeal Cancer. Today is about what boards actually test when they say “survivorship”: whether you understand the *functional price* of cure, and whether you can prove you planned thoughtfully to reduce that price. This episode is going to be constraint-forward. We are going to use a conventional fractionation constraint library (QUANTEC and major protocol-style constraints, plus some institutional planning goals) as the backbone, and we’ll keep circling back to the handful of numbers you must be able to say out loud under pressure.]]></description><guid isPermaLink="false">ec1c02a0-e5fd-490a-886a-d3f5b7d0bba6</guid><pubDate>Sat, 17 Jan 2026 19:17:41 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69490328/9a94df27_36b6_42b1_6ea3_898692c28d60.mp3" length="34197139" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 20: Functional Outcomes and Survivorship in Oropharyngeal Cancer. Today is about what boards actually test when they say “survivorship”: whether you understand the *functional price* of cure, and whether you can prove you planned...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 20: Functional Outcomes and Survivorship in Oropharyngeal Cancer. Today is about what boards actually test when they say “survivorship”: whether you understand the *functional price* of cure, and whether you can prove you planned thoughtfully to reduce that price. This episode is going to be constraint-forward. We are going to use a conventional fractionation constraint library (QUANTEC and major protocol-style constraints, plus some institutional planning goals) as the backbone, and we’ll keep circling back to the handful of numbers you must be able to say out loud under pressure.]]></itunes:summary><itunes:duration>2138</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E19: H PV Negative Oropharynx, Unknown Primary, and Salvage Strategies</title><link>https://www.spreaker.com/episode/h-n-e19-h-pv-negative-oropharynx-unknown-primary-and-salvage-strategies--69434112</link><description><![CDATA[Today is the curveball episode. Boards love these scenarios because they test judgment, sequencing, and restraint. We will do three things. First, we will contrast the tobacco-associated, p16-negative oropharynx patient with the favorable HPV-positive population, because there is no de-escalation lane here. Second, we will develop a clean, board-safe, and unknown primary workup that escalates logically and efficiently — ultimately leading to the modern transoral diagnostic step, which can localize the primary at high rates. Third, we will walk through salvage strategy selection in previously irradiated patients — who to push, who to spare, and how to talk about it.]]></description><guid isPermaLink="false">119654ec-9068-4bbf-985e-1fc0bfb30b78</guid><pubDate>Wed, 14 Jan 2026 08:09:24 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69434112/70ae7a81_861a_d775_8085_aa027a1ba892.mp3" length="41335046" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today is the curveball episode. Boards love these scenarios because they test judgment, sequencing, and restraint. We will do three things. First, we will contrast the tobacco-associated, p16-negative oropharynx patient with the favorable HPV-positive...</itunes:subtitle><itunes:summary><![CDATA[Today is the curveball episode. Boards love these scenarios because they test judgment, sequencing, and restraint. We will do three things. First, we will contrast the tobacco-associated, p16-negative oropharynx patient with the favorable HPV-positive population, because there is no de-escalation lane here. Second, we will develop a clean, board-safe, and unknown primary workup that escalates logically and efficiently — ultimately leading to the modern transoral diagnostic step, which can localize the primary at high rates. Third, we will walk through salvage strategy selection in previously irradiated patients — who to push, who to spare, and how to talk about it.]]></itunes:summary><itunes:duration>2584</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E18b: Post-OP OROPHARYNX Planning Workshop</title><link>https://www.spreaker.com/episode/h-n-e18b-post-op-oropharynx-planning-workshop--69434111</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 18B: The Post-Operative Oropharynx Planning Workshop. Episode Eighteen was the clinic decision: who gets observation, who gets P-O-R-T, and who needs post-op chemoradiation after transoral surgery for H-P-V-positive oropharyngeal cancer. Episode Eighteen-B is the execution: you already decided “radiation alone” or “chemoradiation.” Now you have to contour the surgical bed, choose the right neck volumes, pick a defensible dose tier, and protect swallowing in a patient who has an excellent prognosis. Today is about post-op oropharynx specifically: tonsil, base of tongue, and the risk-adapted post-Tors framework built around ECOG ACRIN E-3-3-1-1.]]></description><guid isPermaLink="false">be054fc0-4eaa-4712-96ad-173801187eca</guid><pubDate>Wed, 14 Jan 2026 07:49:23 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69434111/ad06578a_4db2_47e4_dc09_cd83fb08d21a.mp3" length="27532780" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7vEq0ErhPT1kjRyRCFl3a5/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 18B: The Post-Operative Oropharynx Planning Workshop. Episode Eighteen was the clinic decision: who gets observation, who gets P-O-R-T, and who needs post-op chemoradiation...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 18B: The Post-Operative Oropharynx Planning Workshop. Episode Eighteen was the clinic decision: who gets observation, who gets P-O-R-T, and who needs post-op chemoradiation after transoral surgery for H-P-V-positive oropharyngeal cancer. Episode Eighteen-B is the execution: you already decided “radiation alone” or “chemoradiation.” Now you have to contour the surgical bed, choose the right neck volumes, pick a defensible dose tier, and protect swallowing in a patient who has an excellent prognosis. Today is about post-op oropharynx specifically: tonsil, base of tongue, and the risk-adapted post-Tors framework built around ECOG ACRIN E-3-3-1-1.]]></itunes:summary><itunes:duration>1721</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E18: Oropharynx TORS and De-Escalation</title><link>https://www.spreaker.com/episode/h-n-e18-oropharynx-tors-and-de-escalation--69399118</link><description><![CDATA[This is Episode 18: TORS and De-Escalation. Today we tackle one of the most controversial and actively evolving areas in head and neck oncology: the role of transoral robotic surgery and treatment de-intensification for H-P-V-positive oropharyngeal cancer. This is exceptionally high-yield for boards because examiners love to test whether you can distinguish proven standards from promising-but-investigational strategies. Here is the core tension you must understand: H-P-V-positive oropharyngeal cancer hasan excellent prognosis with standard chemoradiation, with five-year overall survival exceeding eighty-five percent. This favorable biology has generated enormous enthusiasm for de-escalation, meaning reducing treatment intensity to preserve function while maintaining cure. But enthusiasm is not evidence. Multiple de-escalation strategies have failed in Phase Three testing, and the examiner will probe whether you know the difference between what is proven and what remains investigational. By the end of this episode, you will be able to articulate TORS candidacy criteria, navigate the E-C-O-G-A-C-R-I-N E-three-three-eleven risk stratification system, explain why N-R-G H-N-zero-zero-five closed its dose-reduced arm, and deliver board-safe answers that acknowledge nuance without overstating evidence.]]></description><guid isPermaLink="false">19d0b311-6d01-42f8-b4e0-b3ed7e80396f</guid><pubDate>Mon, 12 Jan 2026 08:10:01 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69399118/85b00b78_30d3_fcd7_423e_79f73e85ba52.mp3" length="42894452" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 18: TORS and De-Escalation. Today we tackle one of the most controversial and actively evolving areas in head and neck oncology: the role of transoral robotic surgery and treatment de-intensification for H-P-V-positive oropharyngeal...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 18: TORS and De-Escalation. Today we tackle one of the most controversial and actively evolving areas in head and neck oncology: the role of transoral robotic surgery and treatment de-intensification for H-P-V-positive oropharyngeal cancer. This is exceptionally high-yield for boards because examiners love to test whether you can distinguish proven standards from promising-but-investigational strategies. Here is the core tension you must understand: H-P-V-positive oropharyngeal cancer hasan excellent prognosis with standard chemoradiation, with five-year overall survival exceeding eighty-five percent. This favorable biology has generated enormous enthusiasm for de-escalation, meaning reducing treatment intensity to preserve function while maintaining cure. But enthusiasm is not evidence. Multiple de-escalation strategies have failed in Phase Three testing, and the examiner will probe whether you know the difference between what is proven and what remains investigational. By the end of this episode, you will be able to articulate TORS candidacy criteria, navigate the E-C-O-G-A-C-R-I-N E-three-three-eleven risk stratification system, explain why N-R-G H-N-zero-zero-five closed its dose-reduced arm, and deliver board-safe answers that acknowledge nuance without overstating evidence.]]></itunes:summary><itunes:duration>2681</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E17B: Oropharynx Definitive Planning Workshop Simulation, Target Volumes, and OAR Constraints</title><link>https://www.spreaker.com/episode/h-n-e17b-oropharynx-definitive-planning-workshop-simulation-target-volumes-and-oar-constraints--69399120</link><description><![CDATA[This is Episode 17b: Definitive Planning Workshop Simulation, Target Volumes, and OAR Constraints. In Episode 17, we covered the clinical decision-making for definitive chemoradiation—why we treat, who needs systemic therapy, and which agent to use. Now we're at the contouring workstation, and we need to answer the technical questions: *How* do we treat? This episode is high-yield for both written and oral boards. Examiners love to probe your understanding of target volume delineation, nodal coverage algorithms, and constraint trade-offs. They'll ask why you included or excluded specific nodal levels, how you balance tumor control against late toxicity, and what happens when your plan can't meet all constraints simultaneously. We're going to work through our case patient step by step—from simulation setup through plan evaluation. By the end, you'll have a systematic framework for definitive oropharyngeal cancer planning that you can defend on boards.]]></description><guid isPermaLink="false">3604b26c-2bd0-43bb-b58d-978c2e881542</guid><pubDate>Mon, 12 Jan 2026 08:06:12 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69399120/758b9c36_1a6a_1f7a_61fc_42d1d7ef8ad0.mp3" length="65199794" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 17b: Definitive Planning Workshop Simulation, Target Volumes, and OAR Constraints. In Episode 17, we covered the clinical decision-making for definitive chemoradiation—why we treat, who needs systemic therapy, and which agent to use....</itunes:subtitle><itunes:summary><![CDATA[This is Episode 17b: Definitive Planning Workshop Simulation, Target Volumes, and OAR Constraints. In Episode 17, we covered the clinical decision-making for definitive chemoradiation—why we treat, who needs systemic therapy, and which agent to use. Now we're at the contouring workstation, and we need to answer the technical questions: *How* do we treat? This episode is high-yield for both written and oral boards. Examiners love to probe your understanding of target volume delineation, nodal coverage algorithms, and constraint trade-offs. They'll ask why you included or excluded specific nodal levels, how you balance tumor control against late toxicity, and what happens when your plan can't meet all constraints simultaneously. We're going to work through our case patient step by step—from simulation setup through plan evaluation. By the end, you'll have a systematic framework for definitive oropharyngeal cancer planning that you can defend on boards.]]></itunes:summary><itunes:duration>2717</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E17: Oropharynx Definitive Chemo-RT and Cisplatin is King</title><link>https://www.spreaker.com/episode/h-n-e17-oropharynx-definitive-chemo-rt-and-cisplatin-is-king--69399119</link><description><![CDATA[This is Episode 17: Definitive Chemo-RT Cisplatin is King. This episode is essential for boards. If you remember one thing from today, let it be this: *cisplatin is king*. Concurrent cisplatin with radiation is the standard of care for locally advanced head and neck cancer requiring systemic therapy—and multiple randomized trials have now proven that cetuximab is *not* an acceptable substitute, even though we once hoped it might be. We're going to work through the landmark trials that established concurrent chemoradiation, understand exactly which patients need systemic therapy and which don't, learn the framework for cisplatin-ineligible patients, dissect the cetuximab failures, and master dose-fractionation strategies. By the end, you'll be able to defend your treatment recommendations on oral boards with evidence-based precision.]]></description><guid isPermaLink="false">0b4ac507-c40a-49b6-b23f-b61192c713c1</guid><pubDate>Mon, 12 Jan 2026 08:00:51 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69399119/b770d9da_18d3_5717_8485_b8690feacad2.mp3" length="42127915" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5N0t79u6FzQjjD50ya73Yn/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 17: Definitive Chemo-RT Cisplatin is King. This episode is essential for boards. If you remember one thing from today, let it be this: *cisplatin is king*. Concurrent cisplatin with radiation is the standard of care for locally...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 17: Definitive Chemo-RT Cisplatin is King. This episode is essential for boards. If you remember one thing from today, let it be this: *cisplatin is king*. Concurrent cisplatin with radiation is the standard of care for locally advanced head and neck cancer requiring systemic therapy—and multiple randomized trials have now proven that cetuximab is *not* an acceptable substitute, even though we once hoped it might be. We're going to work through the landmark trials that established concurrent chemoradiation, understand exactly which patients need systemic therapy and which don't, learn the framework for cisplatin-ineligible patients, dissect the cetuximab failures, and master dose-fractionation strategies. By the end, you'll be able to defend your treatment recommendations on oral boards with evidence-based precision.]]></itunes:summary><itunes:duration>2633</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E16: Oropharynx - Foundations</title><link>https://www.spreaker.com/episode/h-n-e16-oropharynx-foundations--69373568</link><description><![CDATA[This is Episode sixteen: Oropharynx Foundations, H.P.V. Biology, and A.J.C.C. Eighth Edition Staging.Today we begin a new block, and I want to set the stage with something fundamental: oropharynx cancer is not one disease. It is two biologically distinct diseases that share an anatomic region.H.P.V. positive oropharynx cancer is virally driven, occurs in a different patient population, and has dramatically better outcomes. H.P.V. negative oropharynx cancer is the traditional tobacco and alcohol-related disease with worse prognosis and different behavior.This distinction is so important that A.J.C.C. eighth edition created separate staging systems for these two entities. That's unprecedented in head and neck oncology.By the end of today, you'll understand why a patient with a large cystic neck node can still have early-stage H.P.V. positive disease — and why that is actually biologically coherent.]]></description><guid isPermaLink="false">fcb4bf13-8000-4936-9385-d1d6dffb0d3e</guid><pubDate>Fri, 09 Jan 2026 15:40:54 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69373568/de337584_6431_967c_3d96_b4f179f31fa7.mp3" length="26452773" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4z27ztayqMkCuf2uv4dEEo/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode sixteen: Oropharynx Foundations, H.P.V. Biology, and A.J.C.C. Eighth Edition Staging.Today we begin a new block, and I want to set the stage with something fundamental: oropharynx cancer is not one disease. It is two biologically...</itunes:subtitle><itunes:summary><![CDATA[This is Episode sixteen: Oropharynx Foundations, H.P.V. Biology, and A.J.C.C. Eighth Edition Staging.Today we begin a new block, and I want to set the stage with something fundamental: oropharynx cancer is not one disease. It is two biologically distinct diseases that share an anatomic region.H.P.V. positive oropharynx cancer is virally driven, occurs in a different patient population, and has dramatically better outcomes. H.P.V. negative oropharynx cancer is the traditional tobacco and alcohol-related disease with worse prognosis and different behavior.This distinction is so important that A.J.C.C. eighth edition created separate staging systems for these two entities. That's unprecedented in head and neck oncology.By the end of today, you'll understand why a patient with a large cystic neck node can still have early-stage H.P.V. positive disease — and why that is actually biologically coherent.]]></itunes:summary><itunes:duration>1654</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E15C: Oral Cavity Capstone — Mock Oral Boards</title><link>https://www.spreaker.com/episode/h-n-e15c-oral-cavity-capstone-mock-oral-boards--69338469</link><description><![CDATA[Today, we simulate the oral board exam in five blocks. Each block has a multi-step main case, then a shorter twist that tests a different high-yield decision point for the same scenario. Treat this as a live exam. Pause after each question to formulate your response. Let’s begin.]]></description><guid isPermaLink="false">23c26c85-5065-4941-9838-e280e7c28c53</guid><pubDate>Wed, 07 Jan 2026 08:35:40 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69338469/9f846306_4d55_4acb_a2ee_7d83327454d4.mp3" length="30159235" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7rEe3IDFm6R4bjssAJSRhm/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we simulate the oral board exam in five blocks. Each block has a multi-step main case, then a shorter twist that tests a different high-yield decision point for the same scenario. Treat this as a live exam. Pause after each question to...</itunes:subtitle><itunes:summary><![CDATA[Today, we simulate the oral board exam in five blocks. Each block has a multi-step main case, then a shorter twist that tests a different high-yield decision point for the same scenario. Treat this as a live exam. Pause after each question to formulate your response. Let’s begin.]]></itunes:summary><itunes:duration>1885</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E15B: Subsite-Specific Coverage for Oral Cavity Cancer</title><link>https://www.spreaker.com/episode/h-n-e15b-subsite-specific-coverage-for-oral-cavity-cancer--69303780</link><description><![CDATA[This is Episode 15B: Subsite-Specific Coverage for Oral Cavity Cancer. You’re sitting at the contouring workstation with a post-operative oral cavity case loaded. The C-T simulation is fused with the best available preoperative imaging. The surgeon has sent you the operative report. And now you face the questions that define whether your plan is correct:Which nodal levels need coverage? Ipsilateral neck only or bilateral? How far do I extend my primary C-T-V? And what anatomic “must-include” structures are unique to this subsite? The oral cavity is not one disease. It’s a family of subsites with different drainage, different paths of spread, and different ways you get burned if you treat them all the same. Today we build subsite-specific contouring templates. You’ll learn which subsites have a low threshold for bilateral coverage, which can be treated ipsilaterally when truly well-lateralized, and what local extension pathways you must respect—every single time.]]></description><guid isPermaLink="false">5040264d-1cf3-44ba-9169-0e161b1ccb57</guid><pubDate>Mon, 05 Jan 2026 07:23:08 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69303780/0623a3f1_6860_38f0_f463_a934ad4a355a.mp3" length="39720888" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 15B: Subsite-Specific Coverage for Oral Cavity Cancer. You’re sitting at the contouring workstation with a post-operative oral cavity case loaded. The C-T simulation is fused with the best available preoperative imaging. The surgeon...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 15B: Subsite-Specific Coverage for Oral Cavity Cancer. You’re sitting at the contouring workstation with a post-operative oral cavity case loaded. The C-T simulation is fused with the best available preoperative imaging. The surgeon has sent you the operative report. And now you face the questions that define whether your plan is correct:Which nodal levels need coverage? Ipsilateral neck only or bilateral? How far do I extend my primary C-T-V? And what anatomic “must-include” structures are unique to this subsite? The oral cavity is not one disease. It’s a family of subsites with different drainage, different paths of spread, and different ways you get burned if you treat them all the same. Today we build subsite-specific contouring templates. You’ll learn which subsites have a low threshold for bilateral coverage, which can be treated ipsilaterally when truly well-lateralized, and what local extension pathways you must respect—every single time.]]></itunes:summary><itunes:duration>2483</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E15A: Perineural Invasion Tracking and Skull Base Extension</title><link>https://www.spreaker.com/episode/h-n-e15a-perineural-invasion-tracking-and-skull-base-extension--69285460</link><description><![CDATA[This is Episode 15A: Perineural Invasion Tracking and Skull Base Extension.The pathology report lands on your desk: “Extensive perineural invasion involving a named nerve measuring zero-point-three millimeters in diameter. Inferior alveolar nerve identified at the deep margin.”Now what?Do you treat the tumor bed and call it a day? Do you track the nerve all the way to the skull base? How far is far enough? And what happens when your C T V starts encroaching on the brainstem and temporal lobe?]]></description><guid isPermaLink="false">2be6ca27-503f-43f9-9793-5a23650a3556</guid><pubDate>Sat, 03 Jan 2026 02:27:10 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69285460/bd4d200e_4d77_b608_2ac0_a047366ebd31.mp3" length="38185724" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/71HHf4mI35QBmsru4PfBH4/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 15A: Perineural Invasion Tracking and Skull Base Extension.The pathology report lands on your desk: “Extensive perineural invasion involving a named nerve measuring zero-point-three millimeters in diameter. Inferior alveolar nerve...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 15A: Perineural Invasion Tracking and Skull Base Extension.The pathology report lands on your desk: “Extensive perineural invasion involving a named nerve measuring zero-point-three millimeters in diameter. Inferior alveolar nerve identified at the deep margin.”Now what?Do you treat the tumor bed and call it a day? Do you track the nerve all the way to the skull base? How far is far enough? And what happens when your C T V starts encroaching on the brainstem and temporal lobe?]]></itunes:summary><itunes:duration>2387</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E14C: Definitive Radiation and Brachytherapy for Oral Cavity Cancer</title><link>https://www.spreaker.com/episode/h-n-e14c-definitive-radiation-and-brachytherapy-for-oral-cavity-cancer--69283012</link><description><![CDATA[This is Episode 14C: Definitive Radiation and Brachytherapy for Oral Cavity Cancer.Throughout this oral cavity series, we’ve emphasized one principle above all: oral cavity cancer is a surgical disease. Surgery first. Radiation in the adjuvant setting. But what happens when surgery isn’t an option?]]></description><guid isPermaLink="false">b35bc553-c20b-4075-805c-2a6925741053</guid><pubDate>Fri, 02 Jan 2026 19:40:43 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69283012/8a94626a_dcaa_ecb8_744e_b17daeed1d59.mp3" length="37155872" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0xruD3GbTc4vUzJWyHec1d/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 14C: Definitive Radiation and Brachytherapy for Oral Cavity Cancer.Throughout this oral cavity series, we’ve emphasized one principle above all: oral cavity cancer is a surgical disease. Surgery first. Radiation in the adjuvant...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 14C: Definitive Radiation and Brachytherapy for Oral Cavity Cancer.Throughout this oral cavity series, we’ve emphasized one principle above all: oral cavity cancer is a surgical disease. Surgery first. Radiation in the adjuvant setting. But what happens when surgery isn’t an option?]]></itunes:summary><itunes:duration>2323</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E14B:Planning with Reconstruction - Flaps, Hardware, and the O.R.N</title><link>https://www.spreaker.com/episode/h-n-e14b-planning-with-reconstruction-flaps-hardware-and-the-o-r-n--69265747</link><description><![CDATA[This is Episode fourteen B: Planning with Reconstruction - Flaps, Hardware, and the O.R.N. Trade-Off.In Episode eleven B, we built your planning vocabulary: simulation, volumes, nodal levels, and O.A.R. priorities. But that episode assumed a straightforward post-operative bed. What happens when surgery was more complex? When the patient has a fibular free flap reconstructing the mandible? When there's a titanium plate throwing streak artifact across your planning C.T.? When the tumor bed is now buried under transplanted tissue from the thigh or forearm?]]></description><guid isPermaLink="false">dc477dbb-9fd1-4279-8d84-44d07d99aaa5</guid><pubDate>Thu, 01 Jan 2026 07:22:09 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69265747/ad9f3c89_92c4_1360_7318_88ba29fcd910.mp3" length="34668597" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode fourteen B: Planning with Reconstruction - Flaps, Hardware, and the O.R.N. Trade-Off.In Episode eleven B, we built your planning vocabulary: simulation, volumes, nodal levels, and O.A.R. priorities. But that episode assumed a...</itunes:subtitle><itunes:summary><![CDATA[This is Episode fourteen B: Planning with Reconstruction - Flaps, Hardware, and the O.R.N. Trade-Off.In Episode eleven B, we built your planning vocabulary: simulation, volumes, nodal levels, and O.A.R. priorities. But that episode assumed a straightforward post-operative bed. What happens when surgery was more complex? When the patient has a fibular free flap reconstructing the mandible? When there's a titanium plate throwing streak artifact across your planning C.T.? When the tumor bed is now buried under transplanted tissue from the thigh or forearm?]]></itunes:summary><itunes:duration>2167</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E11B: Oral Cavity Sim and Volume</title><link>https://www.spreaker.com/episode/h-n-e11b-oral-cavity-sim-and-volume--69263262</link><description><![CDATA[In Episode eleven A, we established that oral cavity cancer is a surgical disease. We learned the anatomy, the staging, and why surgery wins. But here's the thing: when pathology comes back with adverse features, you become the treating physician. And that means you need to know how to plan.This episode builds your technical vocabulary. We're going to cover how to simulate an oral cavity patient, the philosophy behind G-T-V, C-T-V, and P-T-V, the nodal level anatomy you need to draw on a diagram, and the critical structures you must protect. By the end, you'll be able to describe your simulation and volumes in thirty seconds, exactly the way you'll need to on oral boards.]]></description><guid isPermaLink="false">d119eeee-f028-41f6-8fb6-2223c1f66ce1</guid><pubDate>Wed, 31 Dec 2025 20:24:01 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69263262/f4ef5503_b8eb_19c8_5026_f187b90e31ea.mp3" length="32359790" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1LoCisVHevJdtOr8Pz0Djf/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In Episode eleven A, we established that oral cavity cancer is a surgical disease. We learned the anatomy, the staging, and why surgery wins. But here's the thing: when pathology comes back with adverse features, you become the treating physician. And...</itunes:subtitle><itunes:summary><![CDATA[In Episode eleven A, we established that oral cavity cancer is a surgical disease. We learned the anatomy, the staging, and why surgery wins. But here's the thing: when pathology comes back with adverse features, you become the treating physician. And that means you need to know how to plan.This episode builds your technical vocabulary. We're going to cover how to simulate an oral cavity patient, the philosophy behind G-T-V, C-T-V, and P-T-V, the nodal level anatomy you need to draw on a diagram, and the critical structures you must protect. By the end, you'll be able to describe your simulation and volumes in thirty seconds, exactly the way you'll need to on oral boards.]]></itunes:summary><itunes:duration>2023</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E14:Oral Cavity Four — Mandible, Reconstruction, and Bone Invasion Pitfalls</title><link>https://www.spreaker.com/episode/h-n-e14-oral-cavity-four-mandible-reconstruction-and-bone-invasion-pitfalls--69220873</link><description><![CDATA[This is Episode fourteen: Oral Cavity Four — Mandible, Reconstruction, and Bone Invasion Pitfalls.In the previous three episodes, we covered oral cavity anatomy, surgical management, the neck decision, and adjuvant therapy principles. Now we need to tackle what happens when the mandible is in play—and it often is.The mandible is the elephant in the room for oral cavity radiation. Floor of mouth tumors sit directly against the lingual cortex. Lower alveolar ridge cancers arise from the gingiva overlying the bone. Retromolar trigone tumors can extend to the ascending ramus. Even oral tongue cancers can invade the mandible through the floor of mouth.Understanding mandibular anatomy, invasion patterns, surgical options, and osteoradionecrosis prevention is essential for any radiation oncologist treating oral cavity cancer. This episode covers the practical planning considerations you'll face when bone is involved.After this episode, you should be able to answer: When does the mandible require full-dose coverage versus sparing? What drives ORN risk dosimetrically? And what changes when there's a reconstruction flap in the field?Let's get into it.]]></description><guid isPermaLink="false">3442fa48-edaa-4beb-b366-5240a6b8da81</guid><pubDate>Sat, 27 Dec 2025 16:08:52 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69220873/21908b38_a294_8140_d2bb_f5d84a20c362.mp3" length="29345051" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5v1hJflAd3bd6qrwpq8ibH/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode fourteen: Oral Cavity Four — Mandible, Reconstruction, and Bone Invasion Pitfalls.In the previous three episodes, we covered oral cavity anatomy, surgical management, the neck decision, and adjuvant therapy principles. Now we need to...</itunes:subtitle><itunes:summary><![CDATA[This is Episode fourteen: Oral Cavity Four — Mandible, Reconstruction, and Bone Invasion Pitfalls.In the previous three episodes, we covered oral cavity anatomy, surgical management, the neck decision, and adjuvant therapy principles. Now we need to tackle what happens when the mandible is in play—and it often is.The mandible is the elephant in the room for oral cavity radiation. Floor of mouth tumors sit directly against the lingual cortex. Lower alveolar ridge cancers arise from the gingiva overlying the bone. Retromolar trigone tumors can extend to the ascending ramus. Even oral tongue cancers can invade the mandible through the floor of mouth.Understanding mandibular anatomy, invasion patterns, surgical options, and osteoradionecrosis prevention is essential for any radiation oncologist treating oral cavity cancer. This episode covers the practical planning considerations you'll face when bone is involved.After this episode, you should be able to answer: When does the mandible require full-dose coverage versus sparing? What drives ORN risk dosimetrically? And what changes when there's a reconstruction flap in the field?Let's get into it.]]></itunes:summary><itunes:duration>1834</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E13:Oral Cavity Three — PORT versus Post-op Chemo-RT: The "Big Two</title><link>https://www.spreaker.com/episode/h-n-e13-oral-cavity-three-port-versus-post-op-chemo-rt-the-big-two--69220874</link><description><![CDATA[This is Episode thirteen: Oral Cavity Three — PORT versus Post-op Chemo-RT: The "Big Two."In the last two episodes, we established that oral cavity cancer is a surgical disease and that the clinically node-negative neck requires elective treatment when depth of invasion exceeds three to four millimeters. Now the surgery is done. The pathology report is in your hands. The question becomes: what adjuvant therapy does this patient need?This is the domain of two landmark trials that every radiation oncologist must know cold: R-TOG ninety-five-oh-one by Cooper and E-O-R-T-C twenty-two-nine-three-one by Bernier—both published in the New England Journal of Medicine in 2004. These trials established the "Big Two" indications for concurrent chemoradiation: positive margins and extranodal extension.After this episode, you should be able to answer in one sentence: PORT versus chemo-RT, and why?This episode covers the evidence for post-operative radiation, when to add chemotherapy, the critical importance of timing, and how to apply these principles to real cases. Let's get into it.]]></description><guid isPermaLink="false">c67c088c-2abc-4df3-99e1-a2dee3cbd7e6</guid><pubDate>Sat, 27 Dec 2025 15:42:03 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69220874/61184658_d608_39fa_ccf8_1ef36d41113e.mp3" length="36770096" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1IwUW3AREIvEK5IwLacvn7/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode thirteen: Oral Cavity Three — PORT versus Post-op Chemo-RT: The "Big Two."In the last two episodes, we established that oral cavity cancer is a surgical disease and that the clinically node-negative neck requires elective treatment...</itunes:subtitle><itunes:summary><![CDATA[This is Episode thirteen: Oral Cavity Three — PORT versus Post-op Chemo-RT: The "Big Two."In the last two episodes, we established that oral cavity cancer is a surgical disease and that the clinically node-negative neck requires elective treatment when depth of invasion exceeds three to four millimeters. Now the surgery is done. The pathology report is in your hands. The question becomes: what adjuvant therapy does this patient need?This is the domain of two landmark trials that every radiation oncologist must know cold: R-TOG ninety-five-oh-one by Cooper and E-O-R-T-C twenty-two-nine-three-one by Bernier—both published in the New England Journal of Medicine in 2004. These trials established the "Big Two" indications for concurrent chemoradiation: positive margins and extranodal extension.After this episode, you should be able to answer in one sentence: PORT versus chemo-RT, and why?This episode covers the evidence for post-operative radiation, when to add chemotherapy, the critical importance of timing, and how to apply these principles to real cases. Let's get into it.]]></itunes:summary><itunes:duration>2299</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E12: Oral Cavity Two — The Clinically Node-Negative Neck: Elective Dissection, Not Watchful Waiting</title><link>https://www.spreaker.com/episode/h-n-e12-oral-cavity-two-the-clinically-node-negative-neck-elective-dissection-not-watchful-waiting--69220338</link><description><![CDATA[This is Episode twelve: Oral Cavity Two — The Clinically Node-Negative Neck: Elective Dissection, Not Watchful Waiting.In Episode Eleven, we established that oral cavity cancer is a surgical disease and that depth of invasion drives staging and management. We introduced the concept of elective neck dissection for the clinically negative neck. Now we're going to go deep on the evidence. The cN0 neck is one of the classic oral board scenarios. The examiner will present a patient with early oral tongue cancer, clinically and radiographically negative nodes, and ask you what to do with the neck. Observation is only defensible in very superficial tumors with a depth of invasion of three millimeters or less; otherwise, elective treatment is standard. The D'Cruz trial changed everything—and you need to know it inside and out.]]></description><guid isPermaLink="false">9280374b-0d2d-46af-ab0e-9e5f00df4249</guid><pubDate>Sat, 27 Dec 2025 14:40:02 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69220338/129389ee_b387_159a_75e8_19b4d5ec3fae.mp3" length="33100832" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6PDRnthj2Vo1qmKSu0oiiu/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode twelve: Oral Cavity Two — The Clinically Node-Negative Neck: Elective Dissection, Not Watchful Waiting.In Episode Eleven, we established that oral cavity cancer is a surgical disease and that depth of invasion drives staging and...</itunes:subtitle><itunes:summary><![CDATA[This is Episode twelve: Oral Cavity Two — The Clinically Node-Negative Neck: Elective Dissection, Not Watchful Waiting.In Episode Eleven, we established that oral cavity cancer is a surgical disease and that depth of invasion drives staging and management. We introduced the concept of elective neck dissection for the clinically negative neck. Now we're going to go deep on the evidence. The cN0 neck is one of the classic oral board scenarios. The examiner will present a patient with early oral tongue cancer, clinically and radiographically negative nodes, and ask you what to do with the neck. Observation is only defensible in very superficial tumors with a depth of invasion of three millimeters or less; otherwise, elective treatment is standard. The D'Cruz trial changed everything—and you need to know it inside and out.]]></itunes:summary><itunes:duration>2069</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E11: Oral Cavity One — Subsites, Depth of Invasion, and Why Surgery Usually Wins</title><link>https://www.spreaker.com/episode/h-n-e11-oral-cavity-one-subsites-depth-of-invasion-and-why-surgery-usually-wins--69218933</link><description><![CDATA[This is Episode eleven: Oral Cavity One — Subsites, Depth of Invasion, and Why Surgery Usually Wins.Over the next four episodes, we're going to master oral cavity cancer from the perspective of the radiation oncologist preparing for boards. And I want to be clear about something right up front: oral cavity is a surgical disease. Unlike oropharynx, where definitive chemoradiation is standard, oral cavity cancer is treated with surgery first. Our role as radiation oncologists is adjuvant—we come in after the surgeon, and our decisions are driven by what pathology tells us.]]></description><guid isPermaLink="false">ed59953d-3c47-4e49-a2ec-a350eefbed8a</guid><pubDate>Sat, 27 Dec 2025 11:00:10 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69218933/e38f1b4e_9d01_8dfe_00e0_c5881d6a101e.mp3" length="28940466" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2p4lyaBGVlIpiINlqgCTQp/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode eleven: Oral Cavity One — Subsites, Depth of Invasion, and Why Surgery Usually Wins.Over the next four episodes, we're going to master oral cavity cancer from the perspective of the radiation oncologist preparing for boards. And I want...</itunes:subtitle><itunes:summary><![CDATA[This is Episode eleven: Oral Cavity One — Subsites, Depth of Invasion, and Why Surgery Usually Wins.Over the next four episodes, we're going to master oral cavity cancer from the perspective of the radiation oncologist preparing for boards. And I want to be clear about something right up front: oral cavity is a surgical disease. Unlike oropharynx, where definitive chemoradiation is standard, oral cavity cancer is treated with surgery first. Our role as radiation oncologists is adjuvant—we come in after the surgeon, and our decisions are driven by what pathology tells us.]]></itunes:summary><itunes:duration>1809</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E10: Foundations IX — Planning Workshop: IMRT, VMAT, Protons, and OAR Priorities</title><link>https://www.spreaker.com/episode/h-n-e10-foundations-ix-planning-workshop-imrt-vmat-protons-and-oar-priorities--69217340</link><description><![CDATA[This is Episode 10: Foundations IX — Planning Workshop: IMRT, VMAT, Protons, and OAR Priorities.We’ve arrived at the “dark room” episode. Up to now, you’ve made clinical decisions: diagnosis, stage, intent, dose, and fractionation. Now you’re at the console, staring at a CT and a dose cloud, and the boards are essentially asking: “Do you know what matters, and can you keep the patient safe?”]]></description><guid isPermaLink="false">427b10a4-ecd2-4a69-9b22-ab31d1fe745e</guid><pubDate>Sat, 27 Dec 2025 08:05:29 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69217340/091581eb_25a7_1364_372f_e8b4a771b33c.mp3" length="32947859" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7KzwJQrwI0Qzv1gXZBDsfS/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 10: Foundations IX — Planning Workshop: IMRT, VMAT, Protons, and OAR Priorities.We’ve arrived at the “dark room” episode. Up to now, you’ve made clinical decisions: diagnosis, stage, intent, dose, and fractionation. Now you’re at the...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 10: Foundations IX — Planning Workshop: IMRT, VMAT, Protons, and OAR Priorities.We’ve arrived at the “dark room” episode. Up to now, you’ve made clinical decisions: diagnosis, stage, intent, dose, and fractionation. Now you’re at the console, staring at a CT and a dose cloud, and the boards are essentially asking: “Do you know what matters, and can you keep the patient safe?”]]></itunes:summary><itunes:duration>2060</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E09: Foundations VIII — Supportive Care II: Swallow, Aspiration, Trismus, and Osteoradionecrosis</title><link>https://www.spreaker.com/episode/h-n-e09-foundations-viii-supportive-care-ii-swallow-aspiration-trismus-and-osteoradionecrosis--69217339</link><description><![CDATA[This is Episode 9: Foundations VIII — Supportive Care II: Swallow, Aspiration, Trismus, and Osteoradionecrosis.Last episode was: “Don’t lose the patient during treatment.”This episode is: “Don’t ruin the next thirty years of their life.”Head and neck survivorship is different. We’re curing more patients, younger patients, and we’re curing them with treatments that permanently reshape function. Late effects are not side effects. They are the patient’s new baseline.]]></description><guid isPermaLink="false">e38ae2fc-e8cf-4e3a-b0c1-55882e09dcc9</guid><pubDate>Sat, 27 Dec 2025 08:04:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69217339/e44cc4fc_ea85_9e1a_f92c_b0457f6ae237.mp3" length="28135477" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/19lvW5lk4c3I5uHWyRh5nH/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 9: Foundations VIII — Supportive Care II: Swallow, Aspiration, Trismus, and Osteoradionecrosis.Last episode was: “Don’t lose the patient during treatment.”This episode is: “Don’t ruin the next thirty years of their life.”Head and neck...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 9: Foundations VIII — Supportive Care II: Swallow, Aspiration, Trismus, and Osteoradionecrosis.Last episode was: “Don’t lose the patient during treatment.”This episode is: “Don’t ruin the next thirty years of their life.”Head and neck survivorship is different. We’re curing more patients, younger patients, and we’re curing them with treatments that permanently reshape function. Late effects are not side effects. They are the patient’s new baseline.]]></itunes:summary><itunes:duration>1759</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E08: Foundations VII — Supportive Care I: Dental, Nutrition, and Mucositis</title><link>https://www.spreaker.com/episode/h-n-e08-foundations-vii-supportive-care-i-dental-nutrition-and-mucositis--69217345</link><description><![CDATA[This is Episode 8: Foundations VII — Supportive Care I: Dental, Nutrition, and Mucositis.We have spent the last seven episodes talking about how to kill the cancer. Today, we talk about how to keep the patient alive while we do it. On oral boards, supportive care is the great differentiator. A candidate who can recite fractionation trials but cannot explain when to pull a tooth, when to place a PEG, or how to manage week-five mucositis is advertising inexperience.This is the “Don’t Lose the Patient” episode: the pre-treatment checklist, the on-treatment playbook, and the red lines you do not cross.]]></description><guid isPermaLink="false">22c57f6b-b6a0-463f-ab08-991925c5490a</guid><pubDate>Sat, 27 Dec 2025 08:02:52 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69217345/e4498293_08bb_b2df_bd39_1bd37ecbd79f.mp3" length="30807072" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 8: Foundations VII — Supportive Care I: Dental, Nutrition, and Mucositis.We have spent the last seven episodes talking about how to kill the cancer. Today, we talk about how to keep the patient alive while we do it. On oral boards,...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 8: Foundations VII — Supportive Care I: Dental, Nutrition, and Mucositis.We have spent the last seven episodes talking about how to kill the cancer. Today, we talk about how to keep the patient alive while we do it. On oral boards, supportive care is the great differentiator. A candidate who can recite fractionation trials but cannot explain when to pull a tooth, when to place a PEG, or how to manage week-five mucositis is advertising inexperience.This is the “Don’t Lose the Patient” episode: the pre-treatment checklist, the on-treatment playbook, and the red lines you do not cross.]]></itunes:summary><itunes:duration>1926</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E07: Foundations VI — Systemic Therapy With RT: Cisplatin, Cetuximab, and Alternatives</title><link>https://www.spreaker.com/episode/h-n-e07-foundations-vi-systemic-therapy-with-rt-cisplatin-cetuximab-and-alternatives--69217342</link><description><![CDATA[This is Episode 7: Foundations VI — Systemic Therapy With RT: Cisplatin, Cetuximab, and Alternatives.We’ve built the scaffolding: anatomy, staging, and fractionation. Now we add the lever that most reliably increases cure rates in locally advanced head and neck cancer: concurrent systemic therapy.And here’s the board-relevant truth: examiners don’t just test whether you know that “chemo helps.” They test whether you know **who** should get it, **which** regimen is the standard, **when** cisplatin is unsafe, and **why** cetuximab is not a “gentler substitute” in HPV-positive oropharynx.]]></description><guid isPermaLink="false">27827875-fc9c-4160-88a5-13b5aa7bbb73</guid><pubDate>Sat, 27 Dec 2025 08:02:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69217342/6ebdbe18_5d58_c37f_0ba7_90ef66dee2d4.mp3" length="25882259" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0XwHV1DGhlCR3eBDpcuIS0/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 7: Foundations VI — Systemic Therapy With RT: Cisplatin, Cetuximab, and Alternatives.We’ve built the scaffolding: anatomy, staging, and fractionation. Now we add the lever that most reliably increases cure rates in locally advanced...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 7: Foundations VI — Systemic Therapy With RT: Cisplatin, Cetuximab, and Alternatives.We’ve built the scaffolding: anatomy, staging, and fractionation. Now we add the lever that most reliably increases cure rates in locally advanced head and neck cancer: concurrent systemic therapy.And here’s the board-relevant truth: examiners don’t just test whether you know that “chemo helps.” They test whether you know **who** should get it, **which** regimen is the standard, **when** cisplatin is unsafe, and **why** cetuximab is not a “gentler substitute” in HPV-positive oropharynx.]]></itunes:summary><itunes:duration>1618</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E06:Foundations V — Fractionation and Time: Why We Don’t Treat Head and Neck Like Prostate</title><link>https://www.spreaker.com/episode/h-n-e06-foundations-v-fractionation-and-time-why-we-don-t-treat-head-and-neck-like-prostate--69217343</link><description><![CDATA[This is Episode 6: Foundations V — Fractionation and Time: Why We Don’t Treat Head and Neck Like Prostate.In prostate cancer, a week off for a holiday can be inconvenient, but the tumor biology barely flinches. In head and neck squamous cell carcinoma, a week off is not “just a delay.” It is a biological advantage handed to the tumor.Today is the Time Factor episode: overall treatment time, accelerated repopulation, altered fractionation, and—most important for oral boards—what you actually do when treatment gets interrupted.]]></description><guid isPermaLink="false">651caee7-dd4e-42ba-b085-48056beeec48</guid><pubDate>Sat, 27 Dec 2025 08:01:01 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69217343/9529c3e3_fee7_5505_4dac_f6d57e5b945b.mp3" length="32629792" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1vGiKcqhs4SlmB83fVwviw/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 6: Foundations V — Fractionation and Time: Why We Don’t Treat Head and Neck Like Prostate.In prostate cancer, a week off for a holiday can be inconvenient, but the tumor biology barely flinches. In head and neck squamous cell...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 6: Foundations V — Fractionation and Time: Why We Don’t Treat Head and Neck Like Prostate.In prostate cancer, a week off for a holiday can be inconvenient, but the tumor biology barely flinches. In head and neck squamous cell carcinoma, a week off is not “just a delay.” It is a biological advantage handed to the tumor.Today is the Time Factor episode: overall treatment time, accelerated repopulation, altered fractionation, and—most important for oral boards—what you actually do when treatment gets interrupted.]]></itunes:summary><itunes:duration>2040</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E05:Foundations IV — AJCC Staging That Actually Changes Management</title><link>https://www.spreaker.com/episode/h-n-e05-foundations-iv-ajcc-staging-that-actually-changes-management--69215840</link><description><![CDATA[This is Episode 5: Foundations IV — AJCC Staging That Actually Changes Management.Most residents treat staging as paperwork—something you fill out after you’ve already decided the plan. That’s backward. In AJCC Eighth Edition, staging is a decoder ring: it tells you which disease biology you’re dealing with, what patterns of failure to respect, and which high-risk variables will force treatment intensification.]]></description><guid isPermaLink="false">2a92b414-f191-4429-a77a-2aefcea79036</guid><pubDate>Sat, 27 Dec 2025 01:30:22 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69215840/91a47202_d682_d126_6a26_f59994fe2d02.mp3" length="32826233" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6y0PWnzBtpW2Jyswjecmal/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 5: Foundations IV — AJCC Staging That Actually Changes Management.Most residents treat staging as paperwork—something you fill out after you’ve already decided the plan. That’s backward. In AJCC Eighth Edition, staging is a decoder...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 5: Foundations IV — AJCC Staging That Actually Changes Management.Most residents treat staging as paperwork—something you fill out after you’ve already decided the plan. That’s backward. In AJCC Eighth Edition, staging is a decoder ring: it tells you which disease biology you’re dealing with, what patterns of failure to respect, and which high-risk variables will force treatment intensification.]]></itunes:summary><itunes:duration>2052</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/a93585b3ffb9fa833bb5af126b95dbd0.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E04: Unknown Primary — The Neck Mass Without a Mucosal Home</title><link>https://www.spreaker.com/episode/h-n-e04-unknown-primary-the-neck-mass-without-a-mucosal-home--69215839</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition.This is Episode 4: Unknown Primary — The Neck Mass Without a Mucosal Home.In the last episode, we talked about the workup. We scoped, we scanned, and we biopsied. Most of the time, that process finds the culprit — a small tonsil cancer hiding in crypts or a base of tongue tumor you could miss on casual inspection. But sometimes, you do everything right — contrast imaging, PET, examination under anesthesia, directed biopsies, palatine tonsillectomy, and even tongue base sampling — and the pathology still comes back negative for a primary site. Now you have metastatic squamous cell carcinoma in a cervical lymph node and no mucosal home address. That is Unknown Primary.]]></description><guid isPermaLink="false">a55b85d4-fa3c-4d60-86e0-ee7ccbadce08</guid><pubDate>Sat, 27 Dec 2025 01:29:11 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69215839/5b81ccd5_bc67_164e_60a0_8becfd373b3a.mp3" length="30903621" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0GhGRI4eekVItoYfMzEI7p/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Head and Neck edition.This is Episode 4: Unknown Primary — The Neck Mass Without a Mucosal Home.In the last episode, we talked about the workup. We scoped, we scanned, and we biopsied. Most of the time, that...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition.This is Episode 4: Unknown Primary — The Neck Mass Without a Mucosal Home.In the last episode, we talked about the workup. We scoped, we scanned, and we biopsied. Most of the time, that process finds the culprit — a small tonsil cancer hiding in crypts or a base of tongue tumor you could miss on casual inspection. But sometimes, you do everything right — contrast imaging, PET, examination under anesthesia, directed biopsies, palatine tonsillectomy, and even tongue base sampling — and the pathology still comes back negative for a primary site. Now you have metastatic squamous cell carcinoma in a cervical lymph node and no mucosal home address. That is Unknown Primary.]]></itunes:summary><itunes:duration>1932</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E03:Foundations III — Workup Masterclass: Scope, PET, Pan endo, and Biomarkers</title><link>https://www.spreaker.com/episode/h-n-e03-foundations-iii-workup-masterclass-scope-pet-pan-endo-and-biomarkers--69215843</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 3: Foundations III — Workup Masterclass: Scope, PET, Pan endo, and Biomarkers.Today is about the discipline of diagnosis.On oral boards, there is a specific way to fail a head and neck case before you ever draw a contour: you jump to treatment before you have established the diagnosis and stage. That signals immaturity. The examiner is not just testing whether you can plan IMRT. They are testing whether you can think like the attending who owns the whole patient.]]></description><guid isPermaLink="false">95e88258-9f25-4b1a-bf75-bee5496d720f</guid><pubDate>Sat, 27 Dec 2025 01:27:44 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69215843/1502ca83_986e_f401_59e0_5b74e05dfdf3.mp3" length="27288692" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5Wzar8Bx74IXa48ZDOHsgv/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 3: Foundations III — Workup Masterclass: Scope, PET, Pan endo, and Biomarkers.Today is about the discipline of diagnosis.On oral boards, there is a specific way to fail a...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Head and Neck edition. This is Episode 3: Foundations III — Workup Masterclass: Scope, PET, Pan endo, and Biomarkers.Today is about the discipline of diagnosis.On oral boards, there is a specific way to fail a head and neck case before you ever draw a contour: you jump to treatment before you have established the diagnosis and stage. That signals immaturity. The examiner is not just testing whether you can plan IMRT. They are testing whether you can think like the attending who owns the whole patient.]]></itunes:summary><itunes:duration>1706</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E02:Foundations II — Cranial Nerves, PNI Highways, and the Skull Base</title><link>https://www.spreaker.com/episode/h-n-e02-foundations-ii-cranial-nerves-pni-highways-and-the-skull-base--69215841</link><description><![CDATA[This is Episode 2: Foundations II — Cranial Nerves, PNI Highways, and the Skull Base.**Last episode, we mapped lymphatics. Today, we map nerves.Because in head and neck oncology, **perineural invasion is not just a pathology word. It is geography.** It is a route problem. When tumor gets into a nerve, it can travel **from a peripheral skin site or gland to the skull base foramina**, and from there into deeper skull base compartments. That is why PNI changes your clinical target volume.]]></description><guid isPermaLink="false">c2f56544-173e-45e1-bea4-edaf5b321299</guid><pubDate>Sat, 27 Dec 2025 01:25:54 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69215841/ec931dfd_3f69_8b85_abb7_2dfddb581e9f.mp3" length="33696006" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1nQjI0Z2ZTnWcs6OTAJunN/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 2: Foundations II — Cranial Nerves, PNI Highways, and the Skull Base.**Last episode, we mapped lymphatics. Today, we map nerves.Because in head and neck oncology, **perineural invasion is not just a pathology word. It is geography.**...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 2: Foundations II — Cranial Nerves, PNI Highways, and the Skull Base.**Last episode, we mapped lymphatics. Today, we map nerves.Because in head and neck oncology, **perineural invasion is not just a pathology word. It is geography.** It is a route problem. When tumor gets into a nerve, it can travel **from a peripheral skin site or gland to the skull base foramina**, and from there into deeper skull base compartments. That is why PNI changes your clinical target volume.]]></itunes:summary><itunes:duration>2106</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>H&amp;N E01:Foundations I — Neck Levels and Spaces That Change Volumes</title><link>https://www.spreaker.com/episode/h-n-e01-foundations-i-neck-levels-and-spaces-that-change-volumes--69215842</link><description><![CDATA[This is Episode 1: Foundations I — Neck Levels and Spaces That Change Volumes.We are starting this season with anatomy because in head and neck oncology, anatomy is destiny. If you do not understand the drainage pathways, you cannot draw the target. And if you cannot draw the target, you cannot cure the patient—or worse, you cure them but leave them with avoidable, life-altering toxicity. Today, we are not just memorizing lists. We are building the visual framework—the grid—that you will overlay on every CT scan you scroll through for the rest of your career. This is high-yield for written boards because they love drainage patterns, and it is survival for oral boards because a single missed nodal level on a contouring case is an automatic fail.]]></description><guid isPermaLink="false">09c785f1-8c8e-42e6-94d2-b39ffbe674b2</guid><pubDate>Sat, 27 Dec 2025 01:24:42 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/69215842/507babc6_1302_3e43_2e2e_b79bf117af80.mp3" length="34149910" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/08RZHAH4hVuln9RzyMrvfI/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 1: Foundations I — Neck Levels and Spaces That Change Volumes.We are starting this season with anatomy because in head and neck oncology, anatomy is destiny. If you do not understand the drainage pathways, you cannot draw the target....</itunes:subtitle><itunes:summary><![CDATA[This is Episode 1: Foundations I — Neck Levels and Spaces That Change Volumes.We are starting this season with anatomy because in head and neck oncology, anatomy is destiny. If you do not understand the drainage pathways, you cannot draw the target. And if you cannot draw the target, you cannot cure the patient—or worse, you cure them but leave them with avoidable, life-altering toxicity. Today, we are not just memorizing lists. We are building the visual framework—the grid—that you will overlay on every CT scan you scroll through for the rest of your career. This is high-yield for written boards because they love drainage patterns, and it is survival for oral boards because a single missed nodal level on a contouring case is an automatic fail.]]></itunes:summary><itunes:duration>2135</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/bb6fadb4ca7b1a7dad6883fa3501ef2e.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E18: Mock Oral 3 Vulvar, Vaginal, and Complex Recurrence Cases</title><link>https://www.spreaker.com/episode/gyn-e18-mock-oral-3-vulvar-vaginal-and-complex-recurrence-cases--68602210</link><description><![CDATA[This is Episode 18: *Mock Oral Boards 2 – Vulvar, Vaginal, and Complex Recurrence Cases*. This is our **final episode in the GYN series**. In the **next series, we’ll move on to Breast cancer** and build a new mock oral framework there.**Examiner:** In Episode 17, we focused on cervical and endometrial cancer fundamentals and brachytherapy technique. Today we escalate to the “exam-separating” scenarios: unresectable vulvar and vaginal primaries, sentinel node management, pelvic recurrences, re-irradiation, and high-grade toxicities.When you hear the pause, answer out loud as if you are in the hot seat. I’ll then give you a polished performance script and a teaching pearl.]]></description><guid isPermaLink="false">75ab0c2b-c73c-43eb-badc-804a568637be</guid><pubDate>Mon, 17 Nov 2025 11:42:32 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68602210/f4813727_54e4_583d_586e_3e970865fe3b.mp3" length="25498990" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5l1MP16lyA5ksTg6TNhC2d/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 18: *Mock Oral Boards 2 – Vulvar, Vaginal, and Complex Recurrence Cases*. This is our **final episode in the GYN series**. In the **next series, we’ll move on to Breast cancer** and build a new mock oral framework there.**Examiner:**...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 18: *Mock Oral Boards 2 – Vulvar, Vaginal, and Complex Recurrence Cases*. This is our **final episode in the GYN series**. In the **next series, we’ll move on to Breast cancer** and build a new mock oral framework there.**Examiner:** In Episode 17, we focused on cervical and endometrial cancer fundamentals and brachytherapy technique. Today we escalate to the “exam-separating” scenarios: unresectable vulvar and vaginal primaries, sentinel node management, pelvic recurrences, re-irradiation, and high-grade toxicities.When you hear the pause, answer out loud as if you are in the hot seat. I’ll then give you a polished performance script and a teaching pearl.]]></itunes:summary><itunes:duration>1594</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E17: Mock Oral 2 Cervical and Endometrial Cancer</title><link>https://www.spreaker.com/episode/gyn-e17-mock-oral-2-cervical-and-endometrial-cancer--68602212</link><description><![CDATA[Today, we're not just reviewing content; we're practicing the *performance* of the oral boards. I will act as your examiner, providing board-style prompts for eight comprehensive cases, each with a contrasting twist. When you hear the pause, answer out loud, practicing a crisp, structured, and confident response.After each pause, I’ll give you a model answer—a polished performance script—followed by a key teaching pearl.We’ll cover definitive management of locally advanced cervical cancer, risk-stratified adjuvant therapy in endometrial cancer, and crucial techniques and plans for brachytherapy. Let’s begin.]]></description><guid isPermaLink="false">b35ca2ba-57b1-439f-91d8-5f2940323241</guid><pubDate>Mon, 17 Nov 2025 11:39:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68602212/116fd4ab_50f3_b151_c10c_d13cb8c50285.mp3" length="35300133" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5VvmRbwUYrfN5LRzkWkphw/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we're not just reviewing content; we're practicing the *performance* of the oral boards. I will act as your examiner, providing board-style prompts for eight comprehensive cases, each with a contrasting twist. When you hear the pause, answer...</itunes:subtitle><itunes:summary><![CDATA[Today, we're not just reviewing content; we're practicing the *performance* of the oral boards. I will act as your examiner, providing board-style prompts for eight comprehensive cases, each with a contrasting twist. When you hear the pause, answer out loud, practicing a crisp, structured, and confident response.After each pause, I’ll give you a model answer—a polished performance script—followed by a key teaching pearl.We’ll cover definitive management of locally advanced cervical cancer, risk-stratified adjuvant therapy in endometrial cancer, and crucial techniques and plans for brachytherapy. Let’s begin.]]></itunes:summary><itunes:duration>2207</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E16: Brachytherapy — The Oral Boards Performance Guide</title><link>https://www.spreaker.com/episode/gyn-e16-brachytherapy-the-oral-boards-performance-guide--68602214</link><description><![CDATA[Welcome back to Rad Onc Smart Review, GYN Series. This is Episode 16: GYN Brachytherapy — The Oral Boards Performance Guide. Today is a mock oral. I’ll ask; you answer. Then I’ll give teaching pearls. Focus on applicator selection, polished procedural scripts, hybrid escalation, plan read-outs, troubleshooting, and complications. Pause after each question to formulate your answer.]]></description><guid isPermaLink="false">16e73e56-1498-482c-8be2-ae289d5f5b39</guid><pubDate>Mon, 17 Nov 2025 11:37:51 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68602214/78a1d563_831a_83b2_d057_b0c6ed4ff476.mp3" length="32320084" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5JpqZYj0UtdZFMHMuoBvZv/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, GYN Series. This is Episode 16: GYN Brachytherapy — The Oral Boards Performance Guide. Today is a mock oral. I’ll ask; you answer. Then I’ll give teaching pearls. Focus on applicator selection, polished procedural...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, GYN Series. This is Episode 16: GYN Brachytherapy — The Oral Boards Performance Guide. Today is a mock oral. I’ll ask; you answer. Then I’ll give teaching pearls. Focus on applicator selection, polished procedural scripts, hybrid escalation, plan read-outs, troubleshooting, and complications. Pause after each question to formulate your answer.]]></itunes:summary><itunes:duration>2020</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E14: Ovarian Cancer RadOnc Guide</title><link>https://www.spreaker.com/episode/gyn-e14-ovarian-cancer-radonc-guide--68411117</link><description><![CDATA[Ovarian cancer is dominated by surgery and systemic therapy. As radiation oncologists, we’re expert consultants who step in at critical junctures: to clarify staging and risk, to advise on maintenance systemic strategies that shape recurrence patterns, and to deliver highly conformal radiation for palliation or carefully selected oligometastatic disease. Today we’ll cover surgical staging and cytoreduction goals, the modern systemic landscape (including PARP inhibitors and HRD), and radiation’s niche roles—palliative EBRT and SBRT for oligometastatic or oligoprogressive disease.]]></description><guid isPermaLink="false">4135ff4b-fef8-4f34-8843-60e9684a3619</guid><pubDate>Tue, 04 Nov 2025 07:58:22 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68411117/c0317ef8_2b2c_58c9_7a16_371d5790703e.mp3" length="31305697" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3kEf6ZtzaBjanNdA75uzaX/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Ovarian cancer is dominated by surgery and systemic therapy. As radiation oncologists, we’re expert consultants who step in at critical junctures: to clarify staging and risk, to advise on maintenance systemic strategies that shape recurrence...</itunes:subtitle><itunes:summary><![CDATA[Ovarian cancer is dominated by surgery and systemic therapy. As radiation oncologists, we’re expert consultants who step in at critical junctures: to clarify staging and risk, to advise on maintenance systemic strategies that shape recurrence patterns, and to deliver highly conformal radiation for palliation or carefully selected oligometastatic disease. Today we’ll cover surgical staging and cytoreduction goals, the modern systemic landscape (including PARP inhibitors and HRD), and radiation’s niche roles—palliative EBRT and SBRT for oligometastatic or oligoprogressive disease.]]></itunes:summary><itunes:duration>1957</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E14: Vaginal Cancer</title><link>https://www.spreaker.com/episode/gyn-e14-vaginal-cancer--68394006</link><description><![CDATA[Today we will master primary vaginal cancer from first principles to planning. We will start with epidemiology, pathophysiology, and the anatomy that dictates nodal targets. We will explain why definitive radiation is the backbone of curative therapy for most stages. Then we will design a complete plan that combines pelvic EBRT with a brachytherapy boost, including when to choose an interstitial implant rather than a cylinder. By the end, you will be able to choose the correct nodal basins based on tumor location, justify definitive radiation over morbid surgery, and construct a curative EBRT and brachy plan to seventy to eighty-five gray with the right applicator for the residual tumor thickness.]]></description><guid isPermaLink="false">a3a01882-cbd9-4dbf-97e2-81c98852ebd0</guid><pubDate>Mon, 03 Nov 2025 03:32:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68394006/447b08a3_50fe_6c29_2758_75394d1a27ec.mp3" length="40471124" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2pWO88NkmCLjfWVSHnu99t/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today we will master primary vaginal cancer from first principles to planning. We will start with epidemiology, pathophysiology, and the anatomy that dictates nodal targets. We will explain why definitive radiation is the backbone of curative therapy...</itunes:subtitle><itunes:summary><![CDATA[Today we will master primary vaginal cancer from first principles to planning. We will start with epidemiology, pathophysiology, and the anatomy that dictates nodal targets. We will explain why definitive radiation is the backbone of curative therapy for most stages. Then we will design a complete plan that combines pelvic EBRT with a brachytherapy boost, including when to choose an interstitial implant rather than a cylinder. By the end, you will be able to choose the correct nodal basins based on tumor location, justify definitive radiation over morbid surgery, and construct a curative EBRT and brachy plan to seventy to eighty-five gray with the right applicator for the residual tumor thickness.]]></itunes:summary><itunes:duration>2530</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E13: Vulvar Cancer Part 2 Unresectable Disease and a Planning Workshop</title><link>https://www.spreaker.com/episode/gyn-e13-vulvar-cancer-part-2-unresectable-disease-and-a-planning-workshop--68393637</link><description><![CDATA[Last time we built the algorithm for early vulvar cancer—who needs nodes, how sentinel mapping changes the plan, and when to radiate the vulvar bed and groins. Today we turn to the hard one: locally advanced, unresectable disease. We’ll start by defining “unresectable,” walk through the neoadjuvant chemoradiation evidence, and then do a planning workshop you can take straight to clinic: how to contour the inguinofemoral basins without the classic medial miss, how to set doses for elective versus high-risk volumes, and why you should not “midline-block” the vulva when you’re treating positive nodes. We’ll reinforce, repeat where it helps, and keep it board-ready.]]></description><guid isPermaLink="false">cba05a42-4bcb-49bf-850b-90bb2de1ff99</guid><pubDate>Mon, 03 Nov 2025 02:29:36 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68393637/7e190fef_22d7_8f8d_1b98_4811422c7a7b.mp3" length="38805557" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2ENMtzhTFe5aDQD0guG20W/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Last time we built the algorithm for early vulvar cancer—who needs nodes, how sentinel mapping changes the plan, and when to radiate the vulvar bed and groins. Today we turn to the hard one: locally advanced, unresectable disease. We’ll start by...</itunes:subtitle><itunes:summary><![CDATA[Last time we built the algorithm for early vulvar cancer—who needs nodes, how sentinel mapping changes the plan, and when to radiate the vulvar bed and groins. Today we turn to the hard one: locally advanced, unresectable disease. We’ll start by defining “unresectable,” walk through the neoadjuvant chemoradiation evidence, and then do a planning workshop you can take straight to clinic: how to contour the inguinofemoral basins without the classic medial miss, how to set doses for elective versus high-risk volumes, and why you should not “midline-block” the vulva when you’re treating positive nodes. We’ll reinforce, repeat where it helps, and keep it board-ready.]]></itunes:summary><itunes:duration>2426</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E12: Vulvar Cancer Part 1 Foundations and evidence for surgery and adjuvant radiation</title><link>https://www.spreaker.com/episode/gyn-e12-vulvar-cancer-part-1-foundations-and-evidence-for-surgery-and-adjuvant-radiation--68329823</link><description><![CDATA[This is Episode twelve: Vulvar Cancer Part one—Foundations and evidence for surgery and adjuvant radiation. Today we build from first principles—epidemiology, pathophysiology, anatomy, workup, and staging—and then walk the decision tree for surgery, nodes, and radiation using four anchor studies: the depth-of-invasion rule from the GOG era, the GROINSS-V pathway for sentinel nodes, the Heaps margin criteria for the primary, and GOG-thirty-seven for node-positive adjuvant radiation. By the end, you’ll know when to observe, when to re-operate, and when—exactly—to radiate the vulva, groins, and pelvis.]]></description><guid isPermaLink="false">f1a25e2f-8f9b-47c5-aca9-418522eb9ffd</guid><pubDate>Wed, 29 Oct 2025 09:09:49 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68329823/84bcb4c7_cb49_70f1_6e72_05e4e1c0b4f0.mp3" length="36413577" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode twelve: Vulvar Cancer Part one—Foundations and evidence for surgery and adjuvant radiation. Today we build from first principles—epidemiology, pathophysiology, anatomy, workup, and staging—and then walk the decision tree for surgery,...</itunes:subtitle><itunes:summary><![CDATA[This is Episode twelve: Vulvar Cancer Part one—Foundations and evidence for surgery and adjuvant radiation. Today we build from first principles—epidemiology, pathophysiology, anatomy, workup, and staging—and then walk the decision tree for surgery, nodes, and radiation using four anchor studies: the depth-of-invasion rule from the GOG era, the GROINSS-V pathway for sentinel nodes, the Heaps margin criteria for the primary, and GOG-thirty-seven for node-positive adjuvant radiation. By the end, you’ll know when to observe, when to re-operate, and when—exactly—to radiate the vulva, groins, and pelvis.]]></itunes:summary><itunes:duration>2276</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E11: Endometrial Cancer Part 4: Planning adjuvant pelvic IMRT and vaginal cuff HDR brachytherapy</title><link>https://www.spreaker.com/episode/gyn-e11-endometrial-cancer-part-4-planning-adjuvant-pelvic-imrt-and-vaginal-cuff-hdr-brachytherapy--68295620</link><description><![CDATA[Today is a hands-on planning workshop. We’ll simulate, contour, and plan adjuvant pelvic IMRT. Then we’ll master vaginal cuff HDR brachytherapy—from choosing the cylinder to writing the prescription and optimizing dwell times. You’ll also get two short “oral boards canned speeches” you can deliver verbatim on exam day.]]></description><guid isPermaLink="false">1aa7cd75-e6c2-4b45-805c-d3948dce4a98</guid><pubDate>Mon, 27 Oct 2025 10:02:35 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68295620/292f25cf_7740_5e3d_22cd_c595c1c84845.mp3" length="30600182" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today is a hands-on planning workshop. We’ll simulate, contour, and plan adjuvant pelvic IMRT. Then we’ll master vaginal cuff HDR brachytherapy—from choosing the cylinder to writing the prescription and optimizing dwell times. You’ll also get two...</itunes:subtitle><itunes:summary><![CDATA[Today is a hands-on planning workshop. We’ll simulate, contour, and plan adjuvant pelvic IMRT. Then we’ll master vaginal cuff HDR brachytherapy—from choosing the cylinder to writing the prescription and optimizing dwell times. You’ll also get two short “oral boards canned speeches” you can deliver verbatim on exam day.]]></itunes:summary><itunes:duration>1913</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E10B: Endometrial Cancer Part 3.5: Uterine Sarcomas, Carcinosarcoma, and Medically Inoperable Endometrial Cancer</title><link>https://www.spreaker.com/episode/gyn-e10b-endometrial-cancer-part-3-5-uterine-sarcomas-carcinosarcoma-and-medically-inoperable-endometrial-cancer--68295621</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Gyn cancer series. This is a special topics episode focused on three areas that trip people up on consults and in orals: uterine sarcomas, carcinosarcoma, and how to cure medically inoperable endometrial cancer with radiation.]]></description><guid isPermaLink="false">167cf1b6-93b5-4736-808e-9891d5a4fb4a</guid><pubDate>Mon, 27 Oct 2025 09:28:35 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68295621/1705f19b_43f9_4a29_4c2e_5bf3750637c8.mp3" length="36560698" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6boNazl6bI5QScTYx7hoNV/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Gyn cancer series. This is a special topics episode focused on three areas that trip people up on consults and in orals: uterine sarcomas, carcinosarcoma, and how to cure medically inoperable endometrial cancer...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Gyn cancer series. This is a special topics episode focused on three areas that trip people up on consults and in orals: uterine sarcomas, carcinosarcoma, and how to cure medically inoperable endometrial cancer with radiation.]]></itunes:summary><itunes:duration>2285</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E10: Endometrial Cancer Part 3: Advanced-Stage and Recurrent Disease</title><link>https://www.spreaker.com/episode/gyn-e10-endometrial-cancer-part-3-advanced-stage-and-recurrent-disease--68294249</link><description><![CDATA[This is Episode ten: Endometrial Cancer, Part three — high-risk histologies and Stage three through four-A disease, plus what to do when cancer comes back.Last time we mastered adjuvant therapy for early stage. Today we zoom in on who truly benefits from chemo-radiation, how to reconcile Portec-three with G.O.G. two fifty-eight, how molecular subtype changes the plan, and what first-line therapy looks like now for advanced or recurrent disease.]]></description><guid isPermaLink="false">5f3c8b48-1d63-409f-83b1-afab0db879c5</guid><pubDate>Mon, 27 Oct 2025 07:49:35 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68294249/213af68e_2787_c25c_56a4_a778e3f29804.mp3" length="36108884" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2057tHc8Ckq11N0RaNKMmX/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode ten: Endometrial Cancer, Part three — high-risk histologies and Stage three through four-A disease, plus what to do when cancer comes back.Last time we mastered adjuvant therapy for early stage. Today we zoom in on who truly benefits...</itunes:subtitle><itunes:summary><![CDATA[This is Episode ten: Endometrial Cancer, Part three — high-risk histologies and Stage three through four-A disease, plus what to do when cancer comes back.Last time we mastered adjuvant therapy for early stage. Today we zoom in on who truly benefits from chemo-radiation, how to reconcile Portec-three with G.O.G. two fifty-eight, how molecular subtype changes the plan, and what first-line therapy looks like now for advanced or recurrent disease.]]></itunes:summary><itunes:duration>2257</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E09: Endometrial Cancer Part 2: Early-Stage Disease</title><link>https://www.spreaker.com/episode/gyn-e09-endometrial-cancer-part-2-early-stage-disease--68223192</link><description><![CDATA[Last time, we mastered modern staging and SLN mapping. Today, we answer the question you get every week in clinic: Who needs observation, who gets VBT, and who still needs pelvic EBRT? We’ll build the algorithm from GOG 99, PORTEC-1, PORTEC-2, and key updates, and we’ll start with a quick Surgical Corner so we’re crystal-clear on what operation and pathology we’re planning around.]]></description><guid isPermaLink="false">234e9676-90f4-4242-a46e-913490a915d2</guid><pubDate>Tue, 21 Oct 2025 04:55:07 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68223192/937ffece_44f7_cb36_ee12_b6bc452f688b.mp3" length="23786194" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4Jg59ONXwSpY0WN7q0MgAb/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Last time, we mastered modern staging and SLN mapping. Today, we answer the question you get every week in clinic: Who needs observation, who gets VBT, and who still needs pelvic EBRT? We’ll build the algorithm from GOG 99, PORTEC-1, PORTEC-2, and key...</itunes:subtitle><itunes:summary><![CDATA[Last time, we mastered modern staging and SLN mapping. Today, we answer the question you get every week in clinic: Who needs observation, who gets VBT, and who still needs pelvic EBRT? We’ll build the algorithm from GOG 99, PORTEC-1, PORTEC-2, and key updates, and we’ll start with a quick Surgical Corner so we’re crystal-clear on what operation and pathology we’re planning around.]]></itunes:summary><itunes:duration>1487</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0cbd2b8a705269355ddaa650fddf7b8f.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E08: Endometrial Cancer Part 1: Fundamentals</title><link>https://www.spreaker.com/episode/gyn-e08-endometrial-cancer-part-1-fundamentals--68223193</link><description><![CDATA[Today we pivot from cervical to endometrial cancer, the most common gynecologic malignancy in the U.S. While many patients present early, outcomes hinge on understanding the biology and the new 2023 FIGO staging that integrates molecular data. We’ll differentiate classic and molecular subtypes, walk the new staging system, and review why sentinel lymph node biopsy (SLNB) is now the standard for nodal staging.]]></description><guid isPermaLink="false">ba6998ea-7927-4501-b5a4-314aa52913a4</guid><pubDate>Tue, 21 Oct 2025 04:47:39 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68223193/5a4b467c_756b_d496_13a9_bd4c8df6eab4.mp3" length="30476048" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3mCFzshVRmtF9RVB2hEqtg/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today we pivot from cervical to endometrial cancer, the most common gynecologic malignancy in the U.S. While many patients present early, outcomes hinge on understanding the biology and the new 2023 FIGO staging that integrates molecular data. We’ll...</itunes:subtitle><itunes:summary><![CDATA[Today we pivot from cervical to endometrial cancer, the most common gynecologic malignancy in the U.S. While many patients present early, outcomes hinge on understanding the biology and the new 2023 FIGO staging that integrates molecular data. We’ll differentiate classic and molecular subtypes, walk the new staging system, and review why sentinel lymph node biopsy (SLNB) is now the standard for nodal staging.]]></itunes:summary><itunes:duration>1905</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0cbd2b8a705269355ddaa650fddf7b8f.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E07: Cervix Cancer Part 7: New Standards — Immunotherapy, Induction, and Recurrence</title><link>https://www.spreaker.com/episode/gyn-e07-cervix-cancer-part-7-new-standards-immunotherapy-induction-and-recurrence--68085579</link><description><![CDATA[For two decades, concurrent cisplatin-based chemoradiation was the uncontested standard for locally advanced cervix cancer. That foundation still stands—but 2023–2024 ushered in real upgrades. Today, we’ll cover what to add (and when) for definitive therapy, and how first-line systemic therapy has changed for metastatic and recurrent disease.]]></description><guid isPermaLink="false">7e764454-1dfc-42c5-a617-9bc02f9be999</guid><pubDate>Fri, 10 Oct 2025 00:44:16 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68085579/d02dc8ca_e704_c73e_a49e_14cc287aa944.mp3" length="37399960" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4tuy52TWLD0S2WZJLxOWzV/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>For two decades, concurrent cisplatin-based chemoradiation was the uncontested standard for locally advanced cervix cancer. That foundation still stands—but 2023–2024 ushered in real upgrades. Today, we’ll cover what to add (and when) for definitive...</itunes:subtitle><itunes:summary><![CDATA[For two decades, concurrent cisplatin-based chemoradiation was the uncontested standard for locally advanced cervix cancer. That foundation still stands—but 2023–2024 ushered in real upgrades. Today, we’ll cover what to add (and when) for definitive therapy, and how first-line systemic therapy has changed for metastatic and recurrent disease.]]></itunes:summary><itunes:duration>2338</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0cbd2b8a705269355ddaa650fddf7b8f.jpg"/><itunes:season>5</itunes:season><itunes:episode>7</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E06: Cervix Cancer Part 6: Brachytherapy Part B - Technique and Constraints</title><link>https://www.spreaker.com/episode/gyn-e06-cervix-cancer-part-6-brachytherapy-part-b-technique-and-constraints--68075499</link><description><![CDATA[In our last episode, we established why brachytherapy is a mandatory, life-saving component of definitive cervical cancer treatment. Today, we get practical. This is a hands-on workshop covering the "how-to" of brachytherapy. We will walk through the key steps of a tandem and ovoids procedure, learn how to decide when to add interstitial needles, and most importantly, master the dose constraints—the "cheat sheet" of numbers that you absolutely must know to create a safe and effective plan.]]></description><guid isPermaLink="false">f77a139e-7be1-4a78-abd2-900cdff91ce1</guid><pubDate>Thu, 09 Oct 2025 09:31:59 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68075499/576c6aba_2ba1_fbbb_18b1_b57a888813c0.mp3" length="28171839" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3OpphXjrFroER3uBT9CFm2/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we established why brachytherapy is a mandatory, life-saving component of definitive cervical cancer treatment. Today, we get practical. This is a hands-on workshop covering the "how-to" of brachytherapy. We will walk through the...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we established why brachytherapy is a mandatory, life-saving component of definitive cervical cancer treatment. Today, we get practical. This is a hands-on workshop covering the "how-to" of brachytherapy. We will walk through the key steps of a tandem and ovoids procedure, learn how to decide when to add interstitial needles, and most importantly, master the dose constraints—the "cheat sheet" of numbers that you absolutely must know to create a safe and effective plan.]]></itunes:summary><itunes:duration>1761</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0cbd2b8a705269355ddaa650fddf7b8f.jpg"/><itunes:season>5</itunes:season><itunes:episode>6</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E05: Cervix Cancer Part 5: Brachytherapy Part A – Evidence and Rationale</title><link>https://www.spreaker.com/episode/gyn-e05-cervix-cancer-part-5-brachytherapy-part-a-evidence-and-rationale--68075500</link><description><![CDATA[In our last episode, we mastered the modern techniques for planning pelvic external beam radiation. But for the definitive treatment of cervical cancer, EBRT is only the first half of the story. The second, non-negotiable component for achieving a cure is brachytherapy. Today, we’re going to build the case for why brachytherapy is mandatory. We’ll review the powerful evidence demonstrating its survival benefit over external-beam boosts, the critical importance of overall treatment time, and the paradigm shift toward image-guided volumetric targets that has transformed outcomes.]]></description><guid isPermaLink="false">860650d4-01f2-489c-b49b-c49358c40eee</guid><pubDate>Thu, 09 Oct 2025 09:30:57 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68075500/84fc928a_d4c5_7f6f_27cb_3de9b6d3ed9c.mp3" length="29109740" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6kZmszjiFut7ZaRO0CLTga/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we mastered the modern techniques for planning pelvic external beam radiation. But for the definitive treatment of cervical cancer, EBRT is only the first half of the story. The second, non-negotiable component for achieving a...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we mastered the modern techniques for planning pelvic external beam radiation. But for the definitive treatment of cervical cancer, EBRT is only the first half of the story. The second, non-negotiable component for achieving a cure is brachytherapy. Today, we’re going to build the case for why brachytherapy is mandatory. We’ll review the powerful evidence demonstrating its survival benefit over external-beam boosts, the critical importance of overall treatment time, and the paradigm shift toward image-guided volumetric targets that has transformed outcomes.]]></itunes:summary><itunes:duration>1820</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0cbd2b8a705269355ddaa650fddf7b8f.jpg"/><itunes:season>5</itunes:season><itunes:episode>5</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E04: Cervix Cancer Part 4: EBRT Planning Workshop</title><link>https://www.spreaker.com/episode/gyn-e04-cervix-cancer-part-4-ebrt-planning-workshop--68072794</link><description><![CDATA[In our last few episodes, we’ve focused on the “why” and “when” of treating cervical cancer. Today, we shift to the “how.” This is a practical, hands-on workshop: how to simulate, contour pelvic and para-aortic nodes with modern atlases, justify IMRT over 3D, choose an SIB for nodal disease, execute IGRT correctly, and manage toxicities proactively.]]></description><guid isPermaLink="false">7a56a5a4-d0d9-4645-9063-4976889031d1</guid><pubDate>Thu, 09 Oct 2025 03:48:50 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68072794/f6d14219_125d_18ff_8ec4_a9b9b0ce3266.mp3" length="29309942" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1n8ucHH5GHhnxa4mJQdxIJ/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last few episodes, we’ve focused on the “why” and “when” of treating cervical cancer. Today, we shift to the “how.” This is a practical, hands-on workshop: how to simulate, contour pelvic and para-aortic nodes with modern atlases, justify IMRT...</itunes:subtitle><itunes:summary><![CDATA[In our last few episodes, we’ve focused on the “why” and “when” of treating cervical cancer. Today, we shift to the “how.” This is a practical, hands-on workshop: how to simulate, contour pelvic and para-aortic nodes with modern atlases, justify IMRT over 3D, choose an SIB for nodal disease, execute IGRT correctly, and manage toxicities proactively.]]></itunes:summary><itunes:duration>1832</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/cdb82d340963f5f72c6e1964c4ed05b4.jpg"/><itunes:season>5</itunes:season><itunes:episode>4</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E03: Cervix Cancer Part 3: ChemoRT for Locally Advanced Disease</title><link>https://www.spreaker.com/episode/gyn-e03-cervix-cancer-part-3-chemort-for-locally-advanced-disease--68072793</link><description><![CDATA[Today, we are tackling one of the most significant paradigm shifts in the history of radiation oncology: the establishment of concurrent chemoradiation as the definitive standard of care for locally advanced cervical cancer. This isn't just an incremental improvement; it was a revolution that dramatically improved survival for our patients. Understanding the key trials that drove this change is absolutely essential for both your clinical practice and your board exams.]]></description><guid isPermaLink="false">f684e8f7-c4c3-4faf-aa37-e50d69252fab</guid><pubDate>Thu, 09 Oct 2025 03:47:42 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68072793/2b1b562e_ea09_09db_48a2_11b4aa028c8c.mp3" length="27133629" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6rWMe6Ap7G6BAidsiyy5fj/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we are tackling one of the most significant paradigm shifts in the history of radiation oncology: the establishment of concurrent chemoradiation as the definitive standard of care for locally advanced cervical cancer. This isn't just an...</itunes:subtitle><itunes:summary><![CDATA[Today, we are tackling one of the most significant paradigm shifts in the history of radiation oncology: the establishment of concurrent chemoradiation as the definitive standard of care for locally advanced cervical cancer. This isn't just an incremental improvement; it was a revolution that dramatically improved survival for our patients. Understanding the key trials that drove this change is absolutely essential for both your clinical practice and your board exams.]]></itunes:summary><itunes:duration>1696</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0cbd2b8a705269355ddaa650fddf7b8f.jpg"/><itunes:season>5</itunes:season><itunes:episode>3</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E02: Cervix Cancer Part 2: Adjuvant Decisions for the Resected Patient.</title><link>https://www.spreaker.com/episode/gyn-e02-cervix-cancer-part-2-adjuvant-decisions-for-the-resected-patient--68065207</link><description><![CDATA[In our last episode, we established the framework for managing newly diagnosed, early-stage cervical cancer. But what happens when the surgeon calls you for a post-op consult? This is one of the most common and highest-yield scenarios you will face. Today, we're going to master the post-operative decision framework, learning exactly when to recommend observation, when to give adjuvant radiation, and when to add concurrent chemotherapy.]]></description><guid isPermaLink="false">837e6609-2573-4dd0-981f-149b459d3939</guid><pubDate>Wed, 08 Oct 2025 15:21:52 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68065207/ccee41ee_9631_215d_81d9_1e9e33e9612c.mp3" length="24280221" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we established the framework for managing newly diagnosed, early-stage cervical cancer. But what happens when the surgeon calls you for a post-op consult? This is one of the most common and highest-yield scenarios you will face....</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we established the framework for managing newly diagnosed, early-stage cervical cancer. But what happens when the surgeon calls you for a post-op consult? This is one of the most common and highest-yield scenarios you will face. Today, we're going to master the post-operative decision framework, learning exactly when to recommend observation, when to give adjuvant radiation, and when to add concurrent chemotherapy.]]></itunes:summary><itunes:duration>1518</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0cbd2b8a705269355ddaa650fddf7b8f.jpg"/><itunes:season>5</itunes:season><itunes:episode>2</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>GYN E01: Cervix Cancer Part 1: Staging, Workup, and Early-Stage Evidence.</title><link>https://www.spreaker.com/episode/gyn-e01-cervix-cancer-part-1-staging-workup-and-early-stage-evidence--68065208</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Gyn cancer series. This is Episode 1: Cervix Cancer Part 1: Staging, Workup, and Early-Stage Evidence.Today, we're laying the foundation for our entire cervical cancer curriculum. We're going to tackle the critical first steps in managing a new diagnosis: understanding the disease's background, how to properly stage a patient using the modern FIGO system, what workup is essential, and how to counsel a patient on the fundamental choice between primary surgery and primary radiation.]]></description><guid isPermaLink="false">ed4753bc-4210-4d94-8d48-3daaaf5581e7</guid><pubDate>Wed, 08 Oct 2025 15:19:35 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68065208/ad7ebe8b_2ae5_be8c_db7a_b787bb9dc982.mp3" length="35761560" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Gyn cancer series. This is Episode 1: Cervix Cancer Part 1: Staging, Workup, and Early-Stage Evidence.Today, we're laying the foundation for our entire cervical cancer curriculum. We're going to tackle the...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Gyn cancer series. This is Episode 1: Cervix Cancer Part 1: Staging, Workup, and Early-Stage Evidence.Today, we're laying the foundation for our entire cervical cancer curriculum. We're going to tackle the critical first steps in managing a new diagnosis: understanding the disease's background, how to properly stage a patient using the modern FIGO system, what workup is essential, and how to counsel a patient on the fundamental choice between primary surgery and primary radiation.]]></itunes:summary><itunes:duration>2236</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0cbd2b8a705269355ddaa650fddf7b8f.jpg"/><itunes:season>5</itunes:season><itunes:episode>1</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E20C: Mock Oral Benign CNS Tumors &amp; SRS TTS</title><link>https://www.spreaker.com/episode/cns-e20c-mock-oral-benign-cns-tumors-srs-tts--68001165</link><description><![CDATA[This is our final episode in the C.N.S. block, Episode 20C: a comprehensive Case-Based Review of Benign C.N.S. Tumors and Stereotactic Radiosurgery cases.Over the last several episodes, we've systematically dissected the evidence that defines modern C.N.S. oncology, from malignant gliomas to a wide range of benign tumors. Let's continue to put that knowledge to the test. This episode is a mock oral board examination. I will present five comprehensive case blocks. Pause after each question to formulate your own structured response before I provide the model answer and a key teaching pearl.]]></description><guid isPermaLink="false">08def553-3f2c-4ab8-95d1-e5b729f84430</guid><pubDate>Fri, 03 Oct 2025 14:09:11 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/68001165/5712d764_f52e_b930_2335_0cde21884309.mp3" length="29095111" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is our final episode in the C.N.S. block, Episode 20C: a comprehensive Case-Based Review of Benign C.N.S. Tumors and Stereotactic Radiosurgery cases.Over the last several episodes, we've systematically dissected the evidence that defines modern...</itunes:subtitle><itunes:summary><![CDATA[This is our final episode in the C.N.S. block, Episode 20C: a comprehensive Case-Based Review of Benign C.N.S. Tumors and Stereotactic Radiosurgery cases.Over the last several episodes, we've systematically dissected the evidence that defines modern C.N.S. oncology, from malignant gliomas to a wide range of benign tumors. Let's continue to put that knowledge to the test. This episode is a mock oral board examination. I will present five comprehensive case blocks. Pause after each question to formulate your own structured response before I provide the model answer and a key teaching pearl.]]></itunes:summary><itunes:duration>1819</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E20B: Mock Oral: Brain Metastases &amp; Spine Emergencies</title><link>https://www.spreaker.com/episode/cns-e20b-mock-oral-brain-metastases-spine-emergencies--67923785</link><description><![CDATA[Welcome back to Rad Onc Smart Review, C.N.S. Cancer series. Over the last several episodes, we've systematically dissected the evidence that defines modern C.N.S. oncology. We are continuing our mock oral style review of CNS oncology. I will present comprehensive case blocks, covering different clinical scenarios and then pose a series of questions designed to test your knowledge across all core competencies. Pause after each question to formulate your own structured response before I provide the model answer and a key teaching pearl.]]></description><guid isPermaLink="false">3d77476a-9ce2-4bc4-b4f6-2e3f3d83fa77</guid><pubDate>Sat, 27 Sep 2025 16:05:19 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67923785/31f0df56_ca7e_8be9_d6ac_5ef2cd8fb512.mp3" length="52370119" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0GfWd8fh4tufUZk8oop497/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, C.N.S. Cancer series. Over the last several episodes, we've systematically dissected the evidence that defines modern C.N.S. oncology. We are continuing our mock oral style review of CNS oncology. I will present...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, C.N.S. Cancer series. Over the last several episodes, we've systematically dissected the evidence that defines modern C.N.S. oncology. We are continuing our mock oral style review of CNS oncology. I will present comprehensive case blocks, covering different clinical scenarios and then pose a series of questions designed to test your knowledge across all core competencies. Pause after each question to formulate your own structured response before I provide the model answer and a key teaching pearl.]]></itunes:summary><itunes:duration>2183</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>20</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS 20A: HGG LGG Mock Oral</title><link>https://www.spreaker.com/episode/cns-20a-hgg-lgg-mock-oral--67861137</link><description><![CDATA[Over the last several episodes, we've systematically dissected the evidence that defines modern CNS oncology. Today, we put that knowledge to the test. These episodes will follow a mock oral board examination. I will present comprehensive case blocks, covering different clinical scenarios and then pose a series of questions designed to test your knowledge across all core competencies. Pause after each question to formulate your own structured response before I provide the model answer and a key teaching pearl.]]></description><guid isPermaLink="false">005d98cc-b5a3-4a64-a56f-7135059464aa</guid><pubDate>Tue, 23 Sep 2025 04:31:33 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67861137/407977348_44100_2_b9d57f9834e4d.mp3" length="44029635" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/380SVTOq2gl0g9exUyXU8o/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Over the last several episodes, we've systematically dissected the evidence that defines modern CNS oncology. Today, we put that knowledge to the test. These episodes will follow a mock oral board examination. I will present comprehensive case blocks,...</itunes:subtitle><itunes:summary><![CDATA[Over the last several episodes, we've systematically dissected the evidence that defines modern CNS oncology. Today, we put that knowledge to the test. These episodes will follow a mock oral board examination. I will present comprehensive case blocks, covering different clinical scenarios and then pose a series of questions designed to test your knowledge across all core competencies. Pause after each question to formulate your own structured response before I provide the model answer and a key teaching pearl.]]></itunes:summary><itunes:duration>2752</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>20</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Episode 19D: Benign P3d: Rare Benign Rapid Review</title><link>https://www.spreaker.com/episode/episode-19d-benign-p3d-rare-benign-rapid-review--67853729</link><description><![CDATA[Episode 19D: Benign P3d: Rare Benign Rapid Review.Needs editing]]></description><guid isPermaLink="false">f1cfc875-0087-419f-bd6a-be111857eec9</guid><pubDate>Mon, 22 Sep 2025 15:27:47 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67853729/22a97a49_a140_c855_3ba4_455f04530b3c.mp3" length="33059361" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4AVwt875EgXMICz4HFtuVa/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Episode 19D: Benign P3d: Rare Benign Rapid Review.Needs editing</itunes:subtitle><itunes:summary><![CDATA[Episode 19D: Benign P3d: Rare Benign Rapid Review.Needs editing]]></itunes:summary><itunes:duration>2067</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>Episode 19c: Benign P3c</title><link>https://www.spreaker.com/episode/episode-19c-benign-p3c--67853730</link><description><![CDATA[This is Episode 19c: Benign P3c: Trigeminal Neuralgia – SRS for Functional Pain.Needs editing]]></description><guid isPermaLink="false">2d3f6ec4-c41d-48fc-a131-30894cb2bfac</guid><pubDate>Mon, 22 Sep 2025 15:25:25 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67853730/6260d0a7_c3e5_4d72_62c7_9248ea6c0337.mp3" length="35655724" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3OChcxdDGDmtp4LHm17CCa/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 19c: Benign P3c: Trigeminal Neuralgia – SRS for Functional Pain.Needs editing</itunes:subtitle><itunes:summary><![CDATA[This is Episode 19c: Benign P3c: Trigeminal Neuralgia – SRS for Functional Pain.Needs editing]]></itunes:summary><itunes:duration>2229</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>Episode 19b: Benign P3b: AVM Part 2 - SRS Technique, Doses &amp; Toxicity v1</title><link>https://www.spreaker.com/episode/episode-19b-benign-p3b-avm-part-2-srs-technique-doses-toxicity-v1--67853142</link><description><![CDATA[This is Episode 19b: Benign P3b: AVM Part 2 - SRS Technique, Doses &amp; Toxicity. Needs editing]]></description><guid isPermaLink="false">aafd345e-6808-4fb1-9397-f5b8eae81363</guid><pubDate>Mon, 22 Sep 2025 15:23:40 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67853142/407938190_44100_2_3c0430bffc3cc.mp3" length="27023294" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 19b: Benign P3b: AVM Part 2 - SRS Technique, Doses &amp;amp; Toxicity. Needs editing</itunes:subtitle><itunes:summary><![CDATA[This is Episode 19b: Benign P3b: AVM Part 2 - SRS Technique, Doses &amp; Toxicity. Needs editing]]></itunes:summary><itunes:duration>1689</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>19</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E19A: AVM Foundations</title><link>https://www.spreaker.com/episode/cns-e19a-avm-foundations--67577887</link><description><![CDATA[This is Episode 19a, the first in our new two-part series on a fascinating and challenging benign condition: Arteriovenous Malformations, or AVMs. To build a foundational understanding of arteriovenous malformations (AVMs) by covering their biology and risk factors, applying the Spetzler-Martin scale to assess surgical risk, calculating annual hemorrhage risk, and critically dissecting the controversial ARUBA trial.]]></description><guid isPermaLink="false">d28f6bf0-610f-4534-bb00-6d13154ade0a</guid><pubDate>Mon, 01 Sep 2025 06:03:20 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67577887/127113f0_ee18_9916_680b_8a025ee2dad0.mp3" length="30655771" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1znbkXzeTyHGfZF5ewN9e6/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 19a, the first in our new two-part series on a fascinating and challenging benign condition: Arteriovenous Malformations, or AVMs. To build a foundational understanding of arteriovenous malformations (AVMs) by covering their biology...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 19a, the first in our new two-part series on a fascinating and challenging benign condition: Arteriovenous Malformations, or AVMs. To build a foundational understanding of arteriovenous malformations (AVMs) by covering their biology and risk factors, applying the Spetzler-Martin scale to assess surgical risk, calculating annual hemorrhage risk, and critically dissecting the controversial ARUBA trial.]]></itunes:summary><itunes:duration>1916</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>19</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E18D: Non-Glioma Part 2d: Pituitary Adenomas – Functional</title><link>https://www.spreaker.com/episode/cns-e18d-non-glioma-part-2d-pituitary-adenomas-functional--67366306</link><description><![CDATA[In our last episode, we mastered the management of non-functioning pituitary adenomas, where the primary goal of radiation is long-term tumor control. Today, we tackle the more complex world of functional, or secreting, pituitary adenomas. Here, the clinical challenge is entirely different. Our goal is not just to control the size of the tumor, but to achieve biochemical control—to shut down the hormonal overproduction that causes debilitating syndromes like Cushing's disease and acromegaly. This episode will master the distinct, subtype-specific management of these tumors, focusing on their unique goals, the higher radiation doses required, and the differing timelines for hormonal normalization.]]></description><guid isPermaLink="false">ad6bf2d6-1d73-454f-b369-c2ac02d42e47</guid><pubDate>Thu, 14 Aug 2025 09:44:37 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67366306/e7f25048_b3a1_68bc_b226_7b876b7504d4.mp3" length="23834259" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/13gX0KWH4yP8ED0pMDHHar/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we mastered the management of non-functioning pituitary adenomas, where the primary goal of radiation is long-term tumor control. Today, we tackle the more complex world of functional, or secreting, pituitary adenomas. Here, the...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we mastered the management of non-functioning pituitary adenomas, where the primary goal of radiation is long-term tumor control. Today, we tackle the more complex world of functional, or secreting, pituitary adenomas. Here, the clinical challenge is entirely different. Our goal is not just to control the size of the tumor, but to achieve biochemical control—to shut down the hormonal overproduction that causes debilitating syndromes like Cushing's disease and acromegaly. This episode will master the distinct, subtype-specific management of these tumors, focusing on their unique goals, the higher radiation doses required, and the differing timelines for hormonal normalization.]]></itunes:summary><itunes:duration>1490</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS 18C: Non-Glioma Part 2c: Pituitary Adenomas – Non-Functioning</title><link>https://www.spreaker.com/episode/cns-18c-non-glioma-part-2c-pituitary-adenomas-non-functioning--67366307</link><description><![CDATA[In our last two episodes, we mastered the management of vestibular schwannomas. Today, we shift our focus to another common sellar region tumor: the pituitary adenoma. While often discovered incidentally, these tumors can cause significant morbidity through mass effect. In this episode, we will focus specifically on non-functioning pituitary adenomas, covering their comprehensive workup, surgical management, the critical role of adjuvant radiation, and the evidence-based outcomes and toxicities.]]></description><guid isPermaLink="false">a76b481f-faac-4ffe-96d3-8a5dd06f254b</guid><pubDate>Thu, 14 Aug 2025 09:43:25 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67366307/f52d777d_efa6_6c52_813f_b2b3c53ea6ca.mp3" length="21197355" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7fhKs8kbtd48OSDhi7XI21/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last two episodes, we mastered the management of vestibular schwannomas. Today, we shift our focus to another common sellar region tumor: the pituitary adenoma. While often discovered incidentally, these tumors can cause significant morbidity...</itunes:subtitle><itunes:summary><![CDATA[In our last two episodes, we mastered the management of vestibular schwannomas. Today, we shift our focus to another common sellar region tumor: the pituitary adenoma. While often discovered incidentally, these tumors can cause significant morbidity through mass effect. In this episode, we will focus specifically on non-functioning pituitary adenomas, covering their comprehensive workup, surgical management, the critical role of adjuvant radiation, and the evidence-based outcomes and toxicities.]]></itunes:summary><itunes:duration>1325</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E18B: Non-Glioma Part 2b: Vestibular Schwannoma – Radiation Planning</title><link>https://www.spreaker.com/episode/cns-e18b-non-glioma-part-2b-vestibular-schwannoma-radiation-planning--67366310</link><description><![CDATA[In our last episode, we established the foundational framework for managing vestibular schwannomas. We worked up our patient, a 55-year-old man with a Koos Grade II tumor and serviceable hearing, and after reviewing the options, decided that stereotactic radiosurgery offered him the best balance of tumor control and functional preservation. Today, we take him to the treatment planning system. This episode is a deep dive into the technical aspects of radiation for vestibular schwannoma, covering simulation, precise dose prescriptions, critical cranial nerve dose constraints, and long-term follow-up.]]></description><guid isPermaLink="false">2c8946ce-4f7e-428d-b4ac-2e9d4b8645ca</guid><pubDate>Thu, 14 Aug 2025 09:42:07 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67366310/116f0877_d86f_ed92_92db_4887186e2a4f.mp3" length="40920430" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0grQbDIYOEZC4zaOCwD3Fh/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we established the foundational framework for managing vestibular schwannomas. We worked up our patient, a 55-year-old man with a Koos Grade II tumor and serviceable hearing, and after reviewing the options, decided that...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we established the foundational framework for managing vestibular schwannomas. We worked up our patient, a 55-year-old man with a Koos Grade II tumor and serviceable hearing, and after reviewing the options, decided that stereotactic radiosurgery offered him the best balance of tumor control and functional preservation. Today, we take him to the treatment planning system. This episode is a deep dive into the technical aspects of radiation for vestibular schwannoma, covering simulation, precise dose prescriptions, critical cranial nerve dose constraints, and long-term follow-up.]]></itunes:summary><itunes:duration>2558</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E18A: Non-Glioma Part 2a: Vestibular Schwannoma Basics</title><link>https://www.spreaker.com/episode/cns-e18a-non-glioma-part-2a-vestibular-schwannoma-basics--67366309</link><description><![CDATA[Today we're tackling one of the most common non-malignant brain tumors you will treat: the vestibular schwannoma, also known as an acoustic neuroma. While histologically benign, these tumors can cause significant, life-altering morbidity by affecting hearing, balance, and facial function. The management is a masterclass in shared decision-making, balancing excellent tumor control rates against the critical goals of preserving cranial nerve function and quality of life. This episode will lay the complete foundation for managing these tumors, covering the detailed workup, classification, natural history, and the initial decision-making framework.]]></description><guid isPermaLink="false">a55c8009-46ca-4cb8-a746-5424b90eb139</guid><pubDate>Thu, 14 Aug 2025 09:40:24 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67366309/fb945955_bbd3_6218_a55a_1327be51e4c0.mp3" length="29398550" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6UavJinRrU55g7Zzdy61fC/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today we're tackling one of the most common non-malignant brain tumors you will treat: the vestibular schwannoma, also known as an acoustic neuroma. While histologically benign, these tumors can cause significant, life-altering morbidity by affecting...</itunes:subtitle><itunes:summary><![CDATA[Today we're tackling one of the most common non-malignant brain tumors you will treat: the vestibular schwannoma, also known as an acoustic neuroma. While histologically benign, these tumors can cause significant, life-altering morbidity by affecting hearing, balance, and facial function. The management is a masterclass in shared decision-making, balancing excellent tumor control rates against the critical goals of preserving cranial nerve function and quality of life. This episode will lay the complete foundation for managing these tumors, covering the detailed workup, classification, natural history, and the initial decision-making framework.]]></itunes:summary><itunes:duration>1838</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS 17B: Meningioma Part 2 version 1</title><link>https://www.spreaker.com/episode/cns-17b-meningioma-part-2-version-1--67244168</link><description><![CDATA[This is Episode 17b: Non-Glioma Part 2: Atypical &amp; Anaplastic Meningiomas &amp; Future Directions.In Episode 17a, we built the essential foundation for understanding meningiomas, covering their epidemiology, detailed WHO grading, and the management of WHO Grade I tumors. Today, we confront the more challenging and clinically critical aspects: the complex management of Atypical (Grade II) and Anaplastic (Grade III) meningiomas. We will dissect the nuances of adjuvant radiation for these higher-grade tumors, explore strategies for re-irradiation, provide specific radiation planning pearls, and look at the landscape of emerging systemic therapies.]]></description><guid isPermaLink="false">f62d0492-29df-4386-8203-7f58c7f67b92</guid><pubDate>Mon, 04 Aug 2025 09:42:24 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67244168/2e7276f5_b2ea_3064_f78b_209d0f643d6a.mp3" length="27182112" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4vjF8KeXpBflS1BxtafQrD/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 17b: Non-Glioma Part 2: Atypical &amp;amp; Anaplastic Meningiomas &amp;amp; Future Directions.In Episode 17a, we built the essential foundation for understanding meningiomas, covering their epidemiology, detailed WHO grading, and the...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 17b: Non-Glioma Part 2: Atypical &amp; Anaplastic Meningiomas &amp; Future Directions.In Episode 17a, we built the essential foundation for understanding meningiomas, covering their epidemiology, detailed WHO grading, and the management of WHO Grade I tumors. Today, we confront the more challenging and clinically critical aspects: the complex management of Atypical (Grade II) and Anaplastic (Grade III) meningiomas. We will dissect the nuances of adjuvant radiation for these higher-grade tumors, explore strategies for re-irradiation, provide specific radiation planning pearls, and look at the landscape of emerging systemic therapies.]]></itunes:summary><itunes:duration>1699</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E17A Version 1</title><link>https://www.spreaker.com/episode/cns-e17a-version-1--67244170</link><description><![CDATA[This is Episode 17a: Non-Glioma Part 1: Meningioma Foundations &amp; Grade I Management. While gliomas often take the spotlight, the single most common primary intracranial tumor you will encounter is the meningioma. But don't let its often-benign histology fool you; the management of meningiomas is deceptively complex, nuanced, and surprisingly lacking in high-level randomized evidence. Today, we will build a robust framework for managing these tumors, integrating the latest molecular insights. We'll differentiate WHO grades with precision, apply the classic Simpson surgical grades to predict recurrence, detail the comprehensive workup, and then dive into the evidence-based management of WHO Grade I tumors.]]></description><guid isPermaLink="false">ca454820-5023-464d-bdf0-195cdbf077b3</guid><pubDate>Mon, 04 Aug 2025 09:41:08 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67244170/f4c3ca90_cd96_2bc5_e5aa_79d17c2ca8a3.mp3" length="44235265" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7FLVx6PhXmNitN4sfHHko7/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 17a: Non-Glioma Part 1: Meningioma Foundations &amp;amp; Grade I Management. While gliomas often take the spotlight, the single most common primary intracranial tumor you will encounter is the meningioma. But don't let its often-benign...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 17a: Non-Glioma Part 1: Meningioma Foundations &amp; Grade I Management. While gliomas often take the spotlight, the single most common primary intracranial tumor you will encounter is the meningioma. But don't let its often-benign histology fool you; the management of meningiomas is deceptively complex, nuanced, and surprisingly lacking in high-level randomized evidence. Today, we will build a robust framework for managing these tumors, integrating the latest molecular insights. We'll differentiate WHO grades with precision, apply the classic Simpson surgical grades to predict recurrence, detail the comprehensive workup, and then dive into the evidence-based management of WHO Grade I tumors.]]></itunes:summary><itunes:duration>2765</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E16: Spine SBRT Technique &amp; Re-Irradiation Workshop</title><link>https://www.spreaker.com/episode/cns-e16-spine-sbrt-technique-re-irradiation-workshop--67234232</link><description><![CDATA[In our last episode, we laid the complete foundation for managing spinal metastases. Today, we transition from the broad strokes of conventional palliation to the high-precision, high-impact world of Stereotactic Body Radiation Therapy, or SBRT. This episode is a practical workshop. We will cover who to treat with SBRT, a deep dive into the conflicting evidence, how to delineate targets with a step-by-step guide, what critical dose constraints to respect, and finally, how to safely approach the challenge of re-irradiation.]]></description><guid isPermaLink="false">21946957-1dac-4a75-a319-0581b27f1f71</guid><pubDate>Sun, 03 Aug 2025 02:43:43 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67234232/ee7e7f33_0c38_487f_a721_403ee99352ff.mp3" length="33873221" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0lUNPI1nTALZeYL8St8lbF/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we laid the complete foundation for managing spinal metastases. Today, we transition from the broad strokes of conventional palliation to the high-precision, high-impact world of Stereotactic Body Radiation Therapy, or SBRT. This...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we laid the complete foundation for managing spinal metastases. Today, we transition from the broad strokes of conventional palliation to the high-precision, high-impact world of Stereotactic Body Radiation Therapy, or SBRT. This episode is a practical workshop. We will cover who to treat with SBRT, a deep dive into the conflicting evidence, how to delineate targets with a step-by-step guide, what critical dose constraints to respect, and finally, how to safely approach the challenge of re-irradiation.]]></itunes:summary><itunes:duration>2118</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E15B: Spine Mets Part 2: Stability &amp; Cord Compression Management</title><link>https://www.spreaker.com/episode/cns-e15b-spine-mets-part-2-stability-cord-compression-management--67234231</link><description><![CDATA[In Episode 15a, we covered the comprehensive workup for a patient with suspected spinal metastases, from distinguishing pain types to detailed imaging interpretation and initial supportive care. Today, we move to the definitive decisions. We will master the assessment of spinal stability using the SINS score, delineate the Bilsky scale for grading cord compression, and define the evidence-based management of malignant epidural spinal cord compression, including the landmark Patchell trial and modern conventional RT options.]]></description><guid isPermaLink="false">f86732cc-d6c5-49d3-b8c6-9277c48f8ab0</guid><pubDate>Sun, 03 Aug 2025 02:41:59 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67234231/bf7f0c31_f59f_9d42_f735_4c38b0a98144.mp3" length="28540897" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5lOQdpyoW1T9vwZ2Rr2MTi/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In Episode 15a, we covered the comprehensive workup for a patient with suspected spinal metastases, from distinguishing pain types to detailed imaging interpretation and initial supportive care. Today, we move to the definitive decisions. We will...</itunes:subtitle><itunes:summary><![CDATA[In Episode 15a, we covered the comprehensive workup for a patient with suspected spinal metastases, from distinguishing pain types to detailed imaging interpretation and initial supportive care. Today, we move to the definitive decisions. We will master the assessment of spinal stability using the SINS score, delineate the Bilsky scale for grading cord compression, and define the evidence-based management of malignant epidural spinal cord compression, including the landmark Patchell trial and modern conventional RT options.]]></itunes:summary><itunes:duration>1784</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E15A: Spine Mets Part 1: Anatomy &amp; Initial Workup</title><link>https://www.spreaker.com/episode/cns-e15a-spine-mets-part-1-anatomy-initial-workup--67234234</link><description><![CDATA[This is Episode 15a, the first in our new two-part foundational series on Spinal Metastases. Today's episode is titled: "Spine Mets Part 1: Anatomy &amp; Initial Workup."Metastatic disease to the spine is one of the most common and challenging scenarios we face. It can cause debilitating pain, catastrophic neurologic injury, and profoundly impact quality of life. Correct management requires a rapid, systematic approach, and that starts with an impeccable understanding of spinal anatomy and how to interpret imaging. Today, we will build that foundation. We will cover the complete workup, from clinical presentation and imaging to the indications for biopsy. We’ll also refresh our knowledge of essential spinal anatomy, including how to reliably count vertebral levels and ribs on imaging.]]></description><guid isPermaLink="false">930e02c6-6fb5-42c8-b51b-5379da9c971a</guid><pubDate>Sun, 03 Aug 2025 02:36:31 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67234234/19916428_6868_5363_03f2_bd2855ce3173.mp3" length="39677420" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0nmrnFaWaecW3GYI5Ux0tc/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 15a, the first in our new two-part foundational series on Spinal Metastases. Today's episode is titled: "Spine Mets Part 1: Anatomy &amp;amp; Initial Workup."Metastatic disease to the spine is one of the most common and challenging...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 15a, the first in our new two-part foundational series on Spinal Metastases. Today's episode is titled: "Spine Mets Part 1: Anatomy &amp; Initial Workup."Metastatic disease to the spine is one of the most common and challenging scenarios we face. It can cause debilitating pain, catastrophic neurologic injury, and profoundly impact quality of life. Correct management requires a rapid, systematic approach, and that starts with an impeccable understanding of spinal anatomy and how to interpret imaging. Today, we will build that foundation. We will cover the complete workup, from clinical presentation and imaging to the indications for biopsy. We’ll also refresh our knowledge of essential spinal anatomy, including how to reliably count vertebral levels and ribs on imaging.]]></itunes:summary><itunes:duration>2480</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E22:Case-Based Review: Lower GI</title><link>https://www.spreaker.com/episode/g-i-e22-case-based-review-lower-gi--67148540</link><description><![CDATA[This is our mock oral boards for lower GI malignancies. I will present two comprehensive rectal cancer cases, walking you through each one from initial presentation all the way through treatment and follow-up. For each section, I want you to pause and formulate your own structured response before I walk you through the model answer and a key teaching pearl. The goal is to think like an attending and solidify your clinical decision-making from start to finish. Let's get started.]]></description><guid isPermaLink="false">b202f552-8729-4b70-b5d4-12752a1f6876</guid><pubDate>Mon, 28 Jul 2025 03:14:34 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67148540/404662834_44100_2_61b293b7f239a.mp3" length="40678856" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is our mock oral boards for lower GI malignancies. I will present two comprehensive rectal cancer cases, walking you through each one from initial presentation all the way through treatment and follow-up. For each section, I want you to pause and...</itunes:subtitle><itunes:summary><![CDATA[This is our mock oral boards for lower GI malignancies. I will present two comprehensive rectal cancer cases, walking you through each one from initial presentation all the way through treatment and follow-up. For each section, I want you to pause and formulate your own structured response before I walk you through the model answer and a key teaching pearl. The goal is to think like an attending and solidify your clinical decision-making from start to finish. Let's get started.]]></itunes:summary><itunes:duration>2543</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>22</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E21:Case-Based Review: Upper GI v1</title><link>https://www.spreaker.com/episode/g-i-e21-case-based-review-upper-gi-v1--67200109</link><description><![CDATA[Over the last several episodes, we've systematically broken down the evidence that defines modern GI oncology. Today, we put that knowledge to the test. This episode is a mock oral board examination. I will present five comprehensive case blocks, covering Esophageal, Gastric, Pancreatic, Hepatobiliary, and Hepatocellular cancers. For each, I will present a clinical scenario and then pose a series of questions designed to test your knowledge across all core competencies. Pause after each question to formulate your own structured response before I provide the model answer and a key teaching pearl. Let's begin.]]></description><guid isPermaLink="false">b5419d76-2bf2-4f59-844e-8e320d71a5d8</guid><pubDate>Sun, 27 Jul 2025 15:20:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67200109/404876347_44100_2_b3461d87a58f2.mp3" length="41686974" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Over the last several episodes, we've systematically broken down the evidence that defines modern GI oncology. Today, we put that knowledge to the test. This episode is a mock oral board examination. I will present five comprehensive case blocks,...</itunes:subtitle><itunes:summary><![CDATA[Over the last several episodes, we've systematically broken down the evidence that defines modern GI oncology. Today, we put that knowledge to the test. This episode is a mock oral board examination. I will present five comprehensive case blocks, covering Esophageal, Gastric, Pancreatic, Hepatobiliary, and Hepatocellular cancers. For each, I will present a clinical scenario and then pose a series of questions designed to test your knowledge across all core competencies. Pause after each question to formulate your own structured response before I provide the model answer and a key teaching pearl. Let's begin.]]></itunes:summary><itunes:duration>2606</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>22</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E14: Brain Metastases: Case-Based Review and Management Strategies</title><link>https://www.spreaker.com/episode/cns-e14-brain-metastases-case-based-review-and-management-strategies--66970560</link><description><![CDATA[This episode is a mock oral boards session. I will present three distinct, challenging clinical scenarios. For each case, we will walk through the entire management process, from initial presentation all the way through treatment and follow-up, to sharpen your clinical decision-making.]]></description><guid isPermaLink="false">df3101a2-8a3b-433d-acd5-5b20eab05cdb</guid><pubDate>Mon, 14 Jul 2025 04:26:45 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66970560/403866776_44100_2_84a85bd067c0b.mp3" length="21049403" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7MhQ2EuGFr4YoPseKIWWy1/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This episode is a mock oral boards session. I will present three distinct, challenging clinical scenarios. For each case, we will walk through the entire management process, from initial presentation all the way through treatment and follow-up, to...</itunes:subtitle><itunes:summary><![CDATA[This episode is a mock oral boards session. I will present three distinct, challenging clinical scenarios. For each case, we will walk through the entire management process, from initial presentation all the way through treatment and follow-up, to sharpen your clinical decision-making.]]></itunes:summary><itunes:duration>1316</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>14</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E13: Brain Mets #5: SRS Meets IO &amp; Targeted Therapy - A Sequencing Guide</title><link>https://www.spreaker.com/episode/cns-e13-brain-mets-5-srs-meets-io-targeted-therapy-a-sequencing-guide--66970559</link><description><![CDATA[Over the past decade, the landscape of systemic therapy has been transformed by the arrival of immunotherapy and highly effective targeted agents. Many of these drugs have significant intracranial activity, creating a new and complex challenge for the radiation oncologist: how do we sequence our treatments? The old paradigm of "radiation first" is no longer always correct. Today, we will provide a modern guide to navigating this new reality. We will discuss when it's appropriate to defer radiation entirely, compare the CNS efficacy of different systemic regimens, and detail the critical safety considerations and toxicity risks of combining SRS with these powerful new drugs.]]></description><guid isPermaLink="false">d03bb407-343b-4ef0-9cc2-9d776a47040f</guid><pubDate>Mon, 14 Jul 2025 04:25:33 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66970559/403866690_44100_2_77c42d4af9dc8.mp3" length="16297207" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/44ivdsN8vRB9zKjMV4Vm5i/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Over the past decade, the landscape of systemic therapy has been transformed by the arrival of immunotherapy and highly effective targeted agents. Many of these drugs have significant intracranial activity, creating a new and complex challenge for the...</itunes:subtitle><itunes:summary><![CDATA[Over the past decade, the landscape of systemic therapy has been transformed by the arrival of immunotherapy and highly effective targeted agents. Many of these drugs have significant intracranial activity, creating a new and complex challenge for the radiation oncologist: how do we sequence our treatments? The old paradigm of "radiation first" is no longer always correct. Today, we will provide a modern guide to navigating this new reality. We will discuss when it's appropriate to defer radiation entirely, compare the CNS efficacy of different systemic regimens, and detail the critical safety considerations and toxicity risks of combining SRS with these powerful new drugs.]]></itunes:summary><itunes:duration>1019</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E12: Brain Mets #4: 5+ Mets, Large Lesions &amp; Radiation Necrosis.</title><link>https://www.spreaker.com/episode/cns-e12-brain-mets-4-5-mets-large-lesions-radiation-necrosis--66970237</link><description><![CDATA[Today, we address the frontiers of SRS. First, we'll ask: can we treat more than four metastases? Second, how do we safely and effectively treat large metastases that are too big for a single high dose of radiation? And finally, we will tackle the most common and challenging complication of SRS: how to differentiate radiation necrosis from tumor progression.]]></description><guid isPermaLink="false">a50b5fd7-f28c-4d11-bed9-5dd78d68512c</guid><pubDate>Mon, 14 Jul 2025 04:23:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66970237/403866663_44100_2_4dfea9f9fc698.mp3" length="17298637" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we address the frontiers of SRS. First, we'll ask: can we treat more than four metastases? Second, how do we safely and effectively treat large metastases that are too big for a single high dose of radiation? And finally, we will tackle the...</itunes:subtitle><itunes:summary><![CDATA[Today, we address the frontiers of SRS. First, we'll ask: can we treat more than four metastases? Second, how do we safely and effectively treat large metastases that are too big for a single high dose of radiation? And finally, we will tackle the most common and challenging complication of SRS: how to differentiate radiation necrosis from tumor progression.]]></itunes:summary><itunes:duration>1082</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>12</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E11: Brain Mets Part 3: A Post-Op SRS Workshop</title><link>https://www.spreaker.com/episode/cns-e11-brain-mets-part-3-a-post-op-srs-workshop--66970236</link><description><![CDATA[Today, we will conduct a practical workshop on postoperative stereotactic radiosurgery. We'll dissect the two landmark trials that define this practice, learn how to properly delineate a post-operative target volume, and discuss the dreaded complication of nodular leptomeningeal disease.]]></description><guid isPermaLink="false">f31cd741-cfb6-4a05-ad5b-35833a32a489</guid><pubDate>Mon, 14 Jul 2025 04:22:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66970236/403866634_44100_2_945bb7b82e2a4.mp3" length="16394592" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we will conduct a practical workshop on postoperative stereotactic radiosurgery. We'll dissect the two landmark trials that define this practice, learn how to properly delineate a post-operative target volume, and discuss the dreaded...</itunes:subtitle><itunes:summary><![CDATA[Today, we will conduct a practical workshop on postoperative stereotactic radiosurgery. We'll dissect the two landmark trials that define this practice, learn how to properly delineate a post-operative target volume, and discuss the dreaded complication of nodular leptomeningeal disease.]]></itunes:summary><itunes:duration>1025</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>11</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E10: Brain Mets Part 2: The SRS Revolution – When to Omit WBRT</title><link>https://www.spreaker.com/episode/cns-e10-brain-mets-part-2-the-srs-revolution-when-to-omit-wbrt--66970239</link><description><![CDATA[In our last episode, we laid the groundwork for managing brain metastases. Today, we tackle one of the most significant paradigm shifts in modern radiation oncology: the move away from routine whole-brain radiotherapy for patients with a limited number of brain metastases. For decades, WBRT was the standard. Now, for many patients, it's an inferior option. We will walk through the chronological story of the landmark trials that drove this revolution, culminating in the definitive evidence that establishes stereotactic radiosurgery, or SRS, alone as the standard of care for preserving cognitive function.]]></description><guid isPermaLink="false">f5b1d131-4f66-4e31-afee-9baade5e5257</guid><pubDate>Mon, 14 Jul 2025 04:21:28 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66970239/403866604_44100_2_29feb15f5a9a6.mp3" length="19688528" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we laid the groundwork for managing brain metastases. Today, we tackle one of the most significant paradigm shifts in modern radiation oncology: the move away from routine whole-brain radiotherapy for patients with a limited...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we laid the groundwork for managing brain metastases. Today, we tackle one of the most significant paradigm shifts in modern radiation oncology: the move away from routine whole-brain radiotherapy for patients with a limited number of brain metastases. For decades, WBRT was the standard. Now, for many patients, it's an inferior option. We will walk through the chronological story of the landmark trials that drove this revolution, culminating in the definitive evidence that establishes stereotactic radiosurgery, or SRS, alone as the standard of care for preserving cognitive function.]]></itunes:summary><itunes:duration>1231</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>10</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E09: Brain Metastases: Prognosis and WBRT Toolkit</title><link>https://www.spreaker.com/episode/cns-e09-brain-metastases-prognosis-and-wbrt-toolkit--66970238</link><description><![CDATA[Brain metastases are the most common intracranial tumor in adults, and their management has undergone a complete revolution. Before we can treat, we must be able to prognosticate and have a firm grasp of the foundational principles. Today, we will cover the essential background, including epidemiology and workup. We will master the modern prognostic indices, including the Disease-Specific Graded Prognostic Assessment, or D-S-G-P-A. And finally, we will open the whole-brain radiotherapy toolkit, discussing the evidence for adding memantine and detailing the technique and landmark data for hippocampal-avoidance WBRT.]]></description><guid isPermaLink="false">c24e3ca5-7d30-484f-b551-09a534d7b88d</guid><pubDate>Mon, 14 Jul 2025 04:20:34 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66970238/403866523_44100_2_647610d8b9f05.mp3" length="18246569" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Brain metastases are the most common intracranial tumor in adults, and their management has undergone a complete revolution. Before we can treat, we must be able to prognosticate and have a firm grasp of the foundational principles. Today, we will...</itunes:subtitle><itunes:summary><![CDATA[Brain metastases are the most common intracranial tumor in adults, and their management has undergone a complete revolution. Before we can treat, we must be able to prognosticate and have a firm grasp of the foundational principles. Today, we will cover the essential background, including epidemiology and workup. We will master the modern prognostic indices, including the Disease-Specific Graded Prognostic Assessment, or D-S-G-P-A. And finally, we will open the whole-brain radiotherapy toolkit, discussing the evidence for adding memantine and detailing the technique and landmark data for hippocampal-avoidance WBRT.]]></itunes:summary><itunes:duration>1141</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>9</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E08: LGG Part 3: Treatment Planning &amp; Case-Based Review</title><link>https://www.spreaker.com/episode/cns-e08-lgg-part-3-treatment-planning-case-based-review--66967175</link><description><![CDATA[This is Episode 8: Low-Grade Glioma Part 3: Treatment Planning &amp; Case-Based Review. Over the last two episodes, we've built the complete evidence-based framework for managing WHO Grade II gliomas. We've learned how to risk-stratify patients, when to treat, and what regimen to use. Today, we put that knowledge into practice. We'll start with a deep dive into the technical details of treatment planning and toxicity management. Then, we will consolidate our knowledge by working through a series of challenging, oral board-style case scenarios designed to test your clinical decision-making from start to finish.]]></description><guid isPermaLink="false">52fbcd09-4432-4eb8-84b0-1cae3a75755d</guid><pubDate>Sun, 13 Jul 2025 17:51:02 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66967175/403839382_44100_2_e11b39bd5deed.mp3" length="24218370" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3dQZpnLEBmcUdCB4FO4Rqo/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 8: Low-Grade Glioma Part 3: Treatment Planning &amp;amp; Case-Based Review. Over the last two episodes, we've built the complete evidence-based framework for managing WHO Grade II gliomas. We've learned how to risk-stratify patients, when...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 8: Low-Grade Glioma Part 3: Treatment Planning &amp; Case-Based Review. Over the last two episodes, we've built the complete evidence-based framework for managing WHO Grade II gliomas. We've learned how to risk-stratify patients, when to treat, and what regimen to use. Today, we put that knowledge into practice. We'll start with a deep dive into the technical details of treatment planning and toxicity management. Then, we will consolidate our knowledge by working through a series of challenging, oral board-style case scenarios designed to test your clinical decision-making from start to finish.]]></itunes:summary><itunes:duration>1514</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>8</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E07: Low-Grade Glioma: Evidence for Treatment and IDH Inhibitors</title><link>https://www.spreaker.com/episode/cns-e07-low-grade-glioma-evidence-for-treatment-and-idh-inhibitors--66961259</link><description><![CDATA[This is Episode 7: Low-Grade Glioma Part 2: Evidence for Chemo, Dose, and IDH Inhibitors.In our last episode, we established the framework for managing Grade II gliomas, answering the crucial question of when to treat. Today, we address the next logical question: for those high-risk patients we decide to treat, how do we treat them? We will dissect the pivotal evidence that transformed our approach from radiation alone to combined-modality therapy, justify our standard radiation dose by looking at the specific data from the negative dose-escalation trials, and look to the future with the exciting new data on targeted IDH inhibitors.]]></description><guid isPermaLink="false">e4d2ad35-2d0c-450d-a805-199020ed497a</guid><pubDate>Sun, 13 Jul 2025 04:56:07 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66961259/403806903_44100_2_383bfb8d42525.mp3" length="14851904" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/36GmmYDH0W1dZbLBjrA7Ug/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 7: Low-Grade Glioma Part 2: Evidence for Chemo, Dose, and IDH Inhibitors.In our last episode, we established the framework for managing Grade II gliomas, answering the crucial question of when to treat. Today, we address the next...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 7: Low-Grade Glioma Part 2: Evidence for Chemo, Dose, and IDH Inhibitors.In our last episode, we established the framework for managing Grade II gliomas, answering the crucial question of when to treat. Today, we address the next logical question: for those high-risk patients we decide to treat, how do we treat them? We will dissect the pivotal evidence that transformed our approach from radiation alone to combined-modality therapy, justify our standard radiation dose by looking at the specific data from the negative dose-escalation trials, and look to the future with the exciting new data on targeted IDH inhibitors.]]></itunes:summary><itunes:duration>929</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>7</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E06: Low-Grade Gliomas: Foundations, Risk, and Timing</title><link>https://www.spreaker.com/episode/cns-e06-low-grade-gliomas-foundations-risk-and-timing--66961258</link><description><![CDATA[This is Episode 6, and we are kicking off our new mini-series on Low-Grade Gliomas. Today's episode is titled: "LGG P1: Foundations, Risk Stratification &amp; The Timing Debate."For years, the management of WHO Grade II gliomas has been one of the most debated topics in neuro-oncology. These tumors often occur in young, otherwise healthy individuals and have a long natural history, making the decision of when to intervene complex. Today, we will lay the foundation for managing these tumors by first establishing their modern molecular definition, then learning how to use the Pignatti risk factors to stratify patients, and finally, we will dissect the landmark evidence that answers the central, controversial question: Should we treat now, or can we safely watch and wait?]]></description><guid isPermaLink="false">9cdcc888-d5bf-4958-ac5c-1ee9c67578f6</guid><pubDate>Sun, 13 Jul 2025 04:54:58 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66961258/403806868_44100_2_d83676340d617.mp3" length="14202396" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0U1vm7FBvRTaII7ix9Lwln/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 6, and we are kicking off our new mini-series on Low-Grade Gliomas. Today's episode is titled: "LGG P1: Foundations, Risk Stratification &amp;amp; The Timing Debate."For years, the management of WHO Grade II gliomas has been one of the...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 6, and we are kicking off our new mini-series on Low-Grade Gliomas. Today's episode is titled: "LGG P1: Foundations, Risk Stratification &amp; The Timing Debate."For years, the management of WHO Grade II gliomas has been one of the most debated topics in neuro-oncology. These tumors often occur in young, otherwise healthy individuals and have a long natural history, making the decision of when to intervene complex. Today, we will lay the foundation for managing these tumors by first establishing their modern molecular definition, then learning how to use the Pignatti risk factors to stratify patients, and finally, we will dissect the landmark evidence that answers the central, controversial question: Should we treat now, or can we safely watch and wait?]]></itunes:summary><itunes:duration>888</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>6</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E05: HGG Treatment Planning Workshop</title><link>https://www.spreaker.com/episode/cns-e05-hgg-treatment-planning-workshop--66877925</link><description><![CDATA[In our first four episodes, we've established the "what" and the "why" of high-grade glioma management. Today, we get practical and move to the "how." Treatment planning is a core competency for any radiation oncologist, and for high-grade gliomas, it's a discipline of millimeters and nuanced judgments.]]></description><guid isPermaLink="false">02c7a38d-e086-47b7-af4f-862e3d95e750</guid><pubDate>Sun, 06 Jul 2025 20:49:22 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66877925/403413440_44100_2_dd903d933c5b6.mp3" length="24151914" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2y8qUKyFemkIY1zBHeGEP5/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our first four episodes, we've established the "what" and the "why" of high-grade glioma management. Today, we get practical and move to the "how." Treatment planning is a core competency for any radiation oncologist, and for high-grade gliomas,...</itunes:subtitle><itunes:summary><![CDATA[In our first four episodes, we've established the "what" and the "why" of high-grade glioma management. Today, we get practical and move to the "how." Treatment planning is a core competency for any radiation oncologist, and for high-grade gliomas, it's a discipline of millimeters and nuanced judgments.]]></itunes:summary><itunes:duration>1510</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>5</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS 04: HGG: Special Cases and Advanced Treatments</title><link>https://www.spreaker.com/episode/cns-04-hgg-special-cases-and-advanced-treatments--66877924</link><description><![CDATA[In our first three episodes, we mastered the standard approach for a "Stupp-eligible" patient with glioblastoma. But as you know, many of our patients do not fit this mold. They are older, have a lower performance status, or present with the formidable challenge of recurrent disease. Today, we address these special cases head-on. We'll build a framework for treating elderly and frail patients, review the evidence for re-irradiation, and discuss the role of the novel technology, Tumor-Treating Fields.]]></description><guid isPermaLink="false">c9a42870-f907-4648-a3a8-c603806428e7</guid><pubDate>Sun, 06 Jul 2025 20:46:02 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66877924/403413292_44100_2_dfe2cbca07b8a.mp3" length="24433201" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3Jpnj9e4hoAjyr9bi9wcHi/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our first three episodes, we mastered the standard approach for a "Stupp-eligible" patient with glioblastoma. But as you know, many of our patients do not fit this mold. They are older, have a lower performance status, or present with the...</itunes:subtitle><itunes:summary><![CDATA[In our first three episodes, we mastered the standard approach for a "Stupp-eligible" patient with glioblastoma. But as you know, many of our patients do not fit this mold. They are older, have a lower performance status, or present with the formidable challenge of recurrent disease. Today, we address these special cases head-on. We'll build a framework for treating elderly and frail patients, review the evidence for re-irradiation, and discuss the role of the novel technology, Tumor-Treating Fields.]]></itunes:summary><itunes:duration>1527</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>4</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E03: GBM Foundations and The Stupp Protocol</title><link>https://www.spreaker.com/episode/cns-e03-gbm-foundations-and-the-stupp-protocol--66877926</link><description><![CDATA[In our first two episodes, we built the modern diagnostic framework for high-grade gliomas, focusing on anaplastic oligodendrogliomas and astrocytomas. Today, we turn our attention to the most common and most formidable of these tumors: glioblastoma, IDH-wildtype. For years, this diagnosis came with a grim prognosis. But in 2005, one trial created a paradigm shift, establishing the bedrock of modern neuro-oncology. We will do a deep dive into the Stupp protocol and explore why, despite nearly two decades of research, it remains our standard of care.]]></description><guid isPermaLink="false">7a3d6e20-495b-452b-8a26-1401beb66d82</guid><pubDate>Sun, 06 Jul 2025 20:43:43 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66877926/403413216_44100_2_c72f28016508.mp3" length="19805138" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2fsVDnAE10amjYDuAFWwsx/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our first two episodes, we built the modern diagnostic framework for high-grade gliomas, focusing on anaplastic oligodendrogliomas and astrocytomas. Today, we turn our attention to the most common and most formidable of these tumors: glioblastoma,...</itunes:subtitle><itunes:summary><![CDATA[In our first two episodes, we built the modern diagnostic framework for high-grade gliomas, focusing on anaplastic oligodendrogliomas and astrocytomas. Today, we turn our attention to the most common and most formidable of these tumors: glioblastoma, IDH-wildtype. For years, this diagnosis came with a grim prognosis. But in 2005, one trial created a paradigm shift, establishing the bedrock of modern neuro-oncology. We will do a deep dive into the Stupp protocol and explore why, despite nearly two decades of research, it remains our standard of care.]]></itunes:summary><itunes:duration>1238</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>3</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E02: High-Grade Glioma Part 2: Anaplastic Astrocytoma and the Rise of Molecular Grade 4</title><link>https://www.spreaker.com/episode/cns-e02-high-grade-glioma-part-2-anaplastic-astrocytoma-and-the-rise-of-molecular-grade-4--66877927</link><description><![CDATA[In our last episode, we established the modern molecular framework for diagnosing high-grade gliomas and detailed the management of anaplastic oligodendroglioma. Today, we explore the other side of that coin. We will master the management of anaplastic astrocytoma by dissecting the pivotal CATNON trial, and we’ll tackle a challenging new entity introduced in the 2021 WHO classification: the IDH-mutant astrocytoma, Grade 4, a tumor that looks lower-grade under the microscope but carries a much graver prognosis based on its genetics.<br />]]></description><guid isPermaLink="false">8de478f8-fae6-48a4-b085-1c5c8073a855</guid><pubDate>Sun, 06 Jul 2025 20:41:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66877927/403413145_44100_2_29db17e00c819.mp3" length="29966144" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1BDrqTr782eb7LHXUi1ITu/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we established the modern molecular framework for diagnosing high-grade gliomas and detailed the management of anaplastic oligodendroglioma. Today, we explore the other side of that coin. We will master the management of...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we established the modern molecular framework for diagnosing high-grade gliomas and detailed the management of anaplastic oligodendroglioma. Today, we explore the other side of that coin. We will master the management of anaplastic astrocytoma by dissecting the pivotal CATNON trial, and we’ll tackle a challenging new entity introduced in the 2021 WHO classification: the IDH-mutant astrocytoma, Grade 4, a tumor that looks lower-grade under the microscope but carries a much graver prognosis based on its genetics.<br />]]></itunes:summary><itunes:duration>1873</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>2</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>CNS E01: Modern Glioma Classification and Anaplastic Oligodendroglioma</title><link>https://www.spreaker.com/episode/cns-e01-modern-glioma-classification-and-anaplastic-oligodendroglioma--66877928</link><description><![CDATA[Welcome back to Rad Onc Smart Review, CNS Edition.T his is Episode 1 of our new series on CNS oncology, titled: Modern Classification &amp; Anaplastic Oligodendroglioma Evidence. For decades, we treated high-grade gliomas based on what a pathologist saw under a microscope. But in the last ten years, a molecular revolution has completely rewritten the textbook. You cannot treat what you can't accurately diagnose, and the modern diagnosis of glioma is now an integrated, molecular one. Today, we will establish this critical diagnostic framework. Then, we will apply it by taking a deep dive into the management of anaplastic oligodendroglioma, synthesizing the two landmark trials that define its standard of care.]]></description><guid isPermaLink="false">e2b9def3-6f6e-4bf9-92b8-a5d198e99ff5</guid><pubDate>Sun, 06 Jul 2025 20:39:05 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66877928/403412987_44100_2_9ee3597f0499d.mp3" length="21059852" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0FTmoo2eMvo2ZBl3e21jaT/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, CNS Edition.T his is Episode 1 of our new series on CNS oncology, titled: Modern Classification &amp;amp; Anaplastic Oligodendroglioma Evidence. For decades, we treated high-grade gliomas based on what a pathologist...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, CNS Edition.T his is Episode 1 of our new series on CNS oncology, titled: Modern Classification &amp; Anaplastic Oligodendroglioma Evidence. For decades, we treated high-grade gliomas based on what a pathologist saw under a microscope. But in the last ten years, a molecular revolution has completely rewritten the textbook. You cannot treat what you can't accurately diagnose, and the modern diagnosis of glioma is now an integrated, molecular one. Today, we will establish this critical diagnostic framework. Then, we will apply it by taking a deep dive into the management of anaplastic oligodendroglioma, synthesizing the two landmark trials that define its standard of care.]]></itunes:summary><itunes:duration>1317</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/75a8bd91706931f4b628d286687b642b.jpg"/><itunes:season>4</itunes:season><itunes:episode>1</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E20B: Anal Cancer Part 4: Guidelines, Toxicity, Follow-Up &amp; Future Directions</title><link>https://www.spreaker.com/episode/g-i-e20b-anal-cancer-part-4-guidelines-toxicity-follow-up-future-directions--67053716</link><description><![CDATA[This is Episode 20B: Anal Cancer Part 4: Guidelines, Toxicity, Follow-Up &amp; Future Directions. Over the last three episodes, we've built a comprehensive understanding of anal cancer, from its foundational anatomy and staging, to the landmark trials that established definitive chemoradiation, and the technical details of modern IMRT planning. We've learned the 'what,' 'why,' and 'how' of our standard of care. In this final episode of our anal cancer series, we bring everything together. We will synthesize the key recommendations from the landmark 2025 ASTRO Clinical Practice Guideline, which now serves as our primary evidence-based roadmap. We'll then discuss practical strategies for managing acute and late toxicities, outline the evidence-based approach to post-treatment surveillance, and look ahead at the future directions of anal cancer research. ]]></description><guid isPermaLink="false">0bf4fd64-944b-4847-b7ea-fd5126ff64f9</guid><pubDate>Sun, 29 Jun 2025 23:50:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67053716/404261488_44100_2_a1a93639f13a6.mp3" length="33788799" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0T1Q78p3HKP93W9BM1hqzJ/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 20B: Anal Cancer Part 4: Guidelines, Toxicity, Follow-Up &amp;amp; Future Directions. Over the last three episodes, we've built a comprehensive understanding of anal cancer, from its foundational anatomy and staging, to the landmark trials...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 20B: Anal Cancer Part 4: Guidelines, Toxicity, Follow-Up &amp; Future Directions. Over the last three episodes, we've built a comprehensive understanding of anal cancer, from its foundational anatomy and staging, to the landmark trials that established definitive chemoradiation, and the technical details of modern IMRT planning. We've learned the 'what,' 'why,' and 'how' of our standard of care. In this final episode of our anal cancer series, we bring everything together. We will synthesize the key recommendations from the landmark 2025 ASTRO Clinical Practice Guideline, which now serves as our primary evidence-based roadmap. We'll then discuss practical strategies for managing acute and late toxicities, outline the evidence-based approach to post-treatment surveillance, and look ahead at the future directions of anal cancer research. ]]></itunes:summary><itunes:duration>2112</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>20</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E20: Anal Cancer Part 2: IMRT, Planning, and Special Populations</title><link>https://www.spreaker.com/episode/g-i-e20-anal-cancer-part-2-imrt-planning-and-special-populations--66799868</link><description><![CDATA[In our last episode, we established the foundations of anal cancer therapy, proving that definitive chemoradiation with 5-FU and Mitomycin-C is the organ-preserving standard of care. But while this approach is highly effective, it is also notoriously toxic. The older 3D radiation techniques often led to severe side effects and treatment breaks that compromised outcomes.Today, we focus on the modern "how." We'll explore how IMRT has revolutionized our ability to treat this disease. We'll walk through a detailed, dose-painted IMRT planning workshop. And finally, we'll use a case to discuss the management of special populations you will frequently encounter: HIV-positive patients, those with high-risk disease, and those with recurrence.]]></description><guid isPermaLink="false">27f47670-1c8d-4376-9735-25adf4d7e33a</guid><pubDate>Sun, 29 Jun 2025 23:49:07 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66799868/403023067_44100_2_0015c7d2c2f68.mp3" length="20139924" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1dFJpeeDiSe5JQwmQSZa2f/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we established the foundations of anal cancer therapy, proving that definitive chemoradiation with 5-FU and Mitomycin-C is the organ-preserving standard of care. But while this approach is highly effective, it is also notoriously...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we established the foundations of anal cancer therapy, proving that definitive chemoradiation with 5-FU and Mitomycin-C is the organ-preserving standard of care. But while this approach is highly effective, it is also notoriously toxic. The older 3D radiation techniques often led to severe side effects and treatment breaks that compromised outcomes.Today, we focus on the modern "how." We'll explore how IMRT has revolutionized our ability to treat this disease. We'll walk through a detailed, dose-painted IMRT planning workshop. And finally, we'll use a case to discuss the management of special populations you will frequently encounter: HIV-positive patients, those with high-risk disease, and those with recurrence.]]></itunes:summary><itunes:duration>1259</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>20</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E19B: Anal Cancer Part 2: Modern CCRT – Chemo, Dose &amp; Timing</title><link>https://www.spreaker.com/episode/g-i-e19b-anal-cancer-part-2-modern-ccrt-chemo-dose-timing--67053717</link><description><![CDATA[In our last episode, we laid the foundation for anal cancer management, establishing definitive concurrent chemoradiation as the sphincter-sparing standard of care, thanks to the pioneering work of Dr. Nigro and the pivotal ACT I and EORTC trials. We know why we use chemoradiation. Today, we focus on how to optimize it.Modern chemoradiation for anal cancer is a finely tuned balance of three critical components: the right chemotherapy, the right radiation dose, and the right timing. Getting any of these wrong can compromise cure rates or lead to unnecessary toxicity. Today, we’ll dissect the evidence for each of these pillars. We'll compare the key chemotherapy agents, Mitomycin C versus Cisplatin. We’ll justify modern, risk-adapted radiation dose escalation. And we will stress the crucial importance of completing treatment on schedule, without breaks.]]></description><guid isPermaLink="false">b22a8207-9385-4174-af52-64c8f7ae3ca5</guid><pubDate>Sun, 29 Jun 2025 23:42:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67053717/404260547_44100_2_abf39d98069ff.mp3" length="36299062" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5MstBhenWo4lQdf1O4zp0K/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we laid the foundation for anal cancer management, establishing definitive concurrent chemoradiation as the sphincter-sparing standard of care, thanks to the pioneering work of Dr. Nigro and the pivotal ACT I and EORTC trials. We...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we laid the foundation for anal cancer management, establishing definitive concurrent chemoradiation as the sphincter-sparing standard of care, thanks to the pioneering work of Dr. Nigro and the pivotal ACT I and EORTC trials. We know why we use chemoradiation. Today, we focus on how to optimize it.Modern chemoradiation for anal cancer is a finely tuned balance of three critical components: the right chemotherapy, the right radiation dose, and the right timing. Getting any of these wrong can compromise cure rates or lead to unnecessary toxicity. Today, we’ll dissect the evidence for each of these pillars. We'll compare the key chemotherapy agents, Mitomycin C versus Cisplatin. We’ll justify modern, risk-adapted radiation dose escalation. And we will stress the crucial importance of completing treatment on schedule, without breaks.]]></itunes:summary><itunes:duration>2269</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>19</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E19: Anal Cancer Part 1: Anatomy, Foundations, and Modern CCRT</title><link>https://www.spreaker.com/episode/g-i-e19-anal-cancer-part-1-anatomy-foundations-and-modern-ccrt--66799869</link><description><![CDATA[We've arrived at our final primary site in the lower GI tract: anal cancer. In many ways, this disease is the ultimate success story for radiation oncology. It is one of the few solid tumors where we have moved from a paradigm of radical, mutilating surgery to a non-operative, organ-preserving standard of care, with definitive chemoradiation as the backbone. Today, we'll trace the history of this remarkable shift. We’ll start with the fundamentals of anatomy and staging that make anal cancer unique. Then we'll cover the revolutionary Nigro protocol that started it all, and finally, dive deep into the pivotal trials that fine-tuned this approach, answering the key questions of which chemotherapy drugs to use and for how long.]]></description><guid isPermaLink="false">47aeb6d4-8603-4117-bfb8-6d350a42e83a</guid><pubDate>Sun, 29 Jun 2025 23:41:02 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66799869/403022783_44100_2_2558b11ca7105.mp3" length="24253478" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7MZOWzvP3sSmwvkHFh2nU6/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>We've arrived at our final primary site in the lower GI tract: anal cancer. In many ways, this disease is the ultimate success story for radiation oncology. It is one of the few solid tumors where we have moved from a paradigm of radical, mutilating...</itunes:subtitle><itunes:summary><![CDATA[We've arrived at our final primary site in the lower GI tract: anal cancer. In many ways, this disease is the ultimate success story for radiation oncology. It is one of the few solid tumors where we have moved from a paradigm of radical, mutilating surgery to a non-operative, organ-preserving standard of care, with definitive chemoradiation as the backbone. Today, we'll trace the history of this remarkable shift. We’ll start with the fundamentals of anatomy and staging that make anal cancer unique. Then we'll cover the revolutionary Nigro protocol that started it all, and finally, dive deep into the pivotal trials that fine-tuned this approach, answering the key questions of which chemotherapy drugs to use and for how long.]]></itunes:summary><itunes:duration>1516</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E18A: Rectal Cancer Part 4A: Advanced &amp; Recurrent Disease Management</title><link>https://www.spreaker.com/episode/g-i-e18a-rectal-cancer-part-4a-advanced-recurrent-disease-management--67050877</link><description><![CDATA[Today, we shift our focus to managing advanced and recurrent rectal cancer. We will outline the systemic therapy options for metastatic colorectal cancer, including the roles of specific chemotherapies and biologics based on molecular markers. We'll then discuss the critical management of lateral pelvic lymph nodes. Finally, we'll delve into the complex, yet often life-saving, principles of pelvic re-irradiation for recurrent rectal cancer.]]></description><guid isPermaLink="false">6caafef4-b225-4c45-80ca-974c33ba22eb</guid><pubDate>Sun, 29 Jun 2025 23:41:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67050877/404245663_44100_2_396fe305b82ab.mp3" length="30304691" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/43iQJRYc5qoPY4RXWAEnRt/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we shift our focus to managing advanced and recurrent rectal cancer. We will outline the systemic therapy options for metastatic colorectal cancer, including the roles of specific chemotherapies and biologics based on molecular markers. We'll...</itunes:subtitle><itunes:summary><![CDATA[Today, we shift our focus to managing advanced and recurrent rectal cancer. We will outline the systemic therapy options for metastatic colorectal cancer, including the roles of specific chemotherapies and biologics based on molecular markers. We'll then discuss the critical management of lateral pelvic lymph nodes. Finally, we'll delve into the complex, yet often life-saving, principles of pelvic re-irradiation for recurrent rectal cancer.]]></itunes:summary><itunes:duration>1894</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E18B: Rectal Cancer Part 4B: Treatment Planning &amp; Contouring Workshop</title><link>https://www.spreaker.com/episode/g-i-e18b-rectal-cancer-part-4b-treatment-planning-contouring-workshop--67050876</link><description><![CDATA[Today, we're stepping into the treatment planning suite. We'll walk through the entire process, from patient education and simulation setup to the meticulous art of target volume delineation and the critical science of dose selection and OAR constraint application. This episode is your hands-on guide to building a high-quality rectal cancer radiation plan.]]></description><guid isPermaLink="false">da03933d-7fb6-4b85-98eb-be9e0edf2683</guid><pubDate>Sun, 29 Jun 2025 23:41:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67050876/404245787_44100_2_bf647e3b067dd.mp3" length="36906356" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/55KELJGMP7qPGma93RAXLG/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we're stepping into the treatment planning suite. We'll walk through the entire process, from patient education and simulation setup to the meticulous art of target volume delineation and the critical science of dose selection and OAR...</itunes:subtitle><itunes:summary><![CDATA[Today, we're stepping into the treatment planning suite. We'll walk through the entire process, from patient education and simulation setup to the meticulous art of target volume delineation and the critical science of dose selection and OAR constraint application. This episode is your hands-on guide to building a high-quality rectal cancer radiation plan.]]></itunes:summary><itunes:duration>2307</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E18C: Rectal Cancer Part 4C: Toxicity, Follow-Up &amp; Survivorship</title><link>https://www.spreaker.com/episode/g-i-e18c-rectal-cancer-part-4c-toxicity-follow-up-survivorship--67050875</link><description><![CDATA[Today, in our final episode on rectal cancer, we'll equip you with practical strategies for managing acute on-treatment toxicities. We'll then delineate evidence-based follow-up schedules, contrasting operative and non-operative approaches. Finally, we'll explore key survivorship considerations, including fertility preservation, bone health, and the crucial role of pelvic floor rehabilitation.]]></description><guid isPermaLink="false">89a9b389-7378-4a72-9100-2d9c4348e87e</guid><pubDate>Sun, 29 Jun 2025 23:41:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67050875/404245874_44100_2_538d40babc928.mp3" length="24430693" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3rajkdxYbylOCtPA1gI8Aq/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, in our final episode on rectal cancer, we'll equip you with practical strategies for managing acute on-treatment toxicities. We'll then delineate evidence-based follow-up schedules, contrasting operative and non-operative approaches. Finally,...</itunes:subtitle><itunes:summary><![CDATA[Today, in our final episode on rectal cancer, we'll equip you with practical strategies for managing acute on-treatment toxicities. We'll then delineate evidence-based follow-up schedules, contrasting operative and non-operative approaches. Finally, we'll explore key survivorship considerations, including fertility preservation, bone health, and the crucial role of pelvic floor rehabilitation.]]></itunes:summary><itunes:duration>1527</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E18: Rectal Cancer Part 4: Planning, Re-Irradiation &amp; Final Review</title><link>https://www.spreaker.com/episode/g-i-e18-rectal-cancer-part-4-planning-re-irradiation-final-review--66799872</link><description><![CDATA[Over the last three episodes, we have constructed the entire modern framework for rectal cancer management. We’ve established when to treat, how to treat, and who to treat with advanced strategies like TNT and immunotherapy. Today, we bring it all to the treatment planning console.This is the practical application episode. We will provide a step-by-step guide to modern rectal cancer contouring based on international consensus. We'll review critical dose constraints you must know. And finally, we will tackle one of the most complex scenarios in our field—using a case to outline a safe and effective approach to pelvic re-irradiation.]]></description><guid isPermaLink="false">442de84f-ccf6-4c5c-b07b-fbcb1fd7fe30</guid><pubDate>Sun, 29 Jun 2025 23:36:49 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66799872/403022659_44100_2_33286ff58b625.mp3" length="20229785" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5xfp79xKCq6ZOmIgIDcbNk/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Over the last three episodes, we have constructed the entire modern framework for rectal cancer management. We’ve established when to treat, how to treat, and who to treat with advanced strategies like TNT and immunotherapy. Today, we bring it all to...</itunes:subtitle><itunes:summary><![CDATA[Over the last three episodes, we have constructed the entire modern framework for rectal cancer management. We’ve established when to treat, how to treat, and who to treat with advanced strategies like TNT and immunotherapy. Today, we bring it all to the treatment planning console.This is the practical application episode. We will provide a step-by-step guide to modern rectal cancer contouring based on international consensus. We'll review critical dose constraints you must know. And finally, we will tackle one of the most complex scenarios in our field—using a case to outline a safe and effective approach to pelvic re-irradiation.]]></itunes:summary><itunes:duration>1265</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E17C:Rectal Cancer Part 3C: Omission of RT – The PROSPECT Trial Deep Dive</title><link>https://www.spreaker.com/episode/g-i-e17c-rectal-cancer-part-3c-omission-of-rt-the-prospect-trial-deep-dive--67050878</link><description><![CDATA[In our previous discussions, we've firmly established the role of neoadjuvant radiation therapy for locally advanced rectal cancer. However, radiation, while life-saving, comes with its own set of acute and late toxicities—from sexual dysfunction and infertility to chronic bowel changes and the rare risk of secondary malignancies. This raises a crucial question in modern oncology: for whom can we safely omit radiation, de-escalating treatment without compromising oncologic outcomes? Today, we delve into this concept, focusing on a landmark trial that has reshaped our approach to low-risk rectal cancer: the PROSPECT trial. We'll analyze its design, uncover its key findings, and learn how to identify the specific patient population for whom radiation can potentially be spared.]]></description><guid isPermaLink="false">6d23c612-12b3-4f99-8ca7-a0941a3bd0b2</guid><pubDate>Sun, 29 Jun 2025 23:35:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67050878/404244775_44100_2_9de42340624fe.mp3" length="28915813" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2bUKwx58MVWKA5AiSsbTZU/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our previous discussions, we've firmly established the role of neoadjuvant radiation therapy for locally advanced rectal cancer. However, radiation, while life-saving, comes with its own set of acute and late toxicities—from sexual dysfunction and...</itunes:subtitle><itunes:summary><![CDATA[In our previous discussions, we've firmly established the role of neoadjuvant radiation therapy for locally advanced rectal cancer. However, radiation, while life-saving, comes with its own set of acute and late toxicities—from sexual dysfunction and infertility to chronic bowel changes and the rare risk of secondary malignancies. This raises a crucial question in modern oncology: for whom can we safely omit radiation, de-escalating treatment without compromising oncologic outcomes? Today, we delve into this concept, focusing on a landmark trial that has reshaped our approach to low-risk rectal cancer: the PROSPECT trial. We'll analyze its design, uncover its key findings, and learn how to identify the specific patient population for whom radiation can potentially be spared.]]></itunes:summary><itunes:duration>1808</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E17B: Rectal Cancer Part 3B: Organ Preservation and dMMR Management.</title><link>https://www.spreaker.com/episode/g-i-e17b-rectal-cancer-part-3b-organ-preservation-and-dmmr-management--67049521</link><description><![CDATA[In our last episode, we explored Total Neoadjuvant Therapy, or TNT, which has revolutionized the management of high-risk locally advanced rectal cancer by increasing pathologic complete response, or pCR, rates and improving distant control. These impressive pCR rates have opened the door to one of the most exciting and debated topics in rectal cancer: avoiding major surgery through "Watch and Wait," or Non-Operative Management. Today, we dive deep into this organ-preserving approach, defining who is a candidate and what surveillance entails. We'll examine key trials like OPRA and data from the International Watch and Wait Database. Finally, we'll shift to a truly groundbreaking development: the highly effective management of mismatch repair deficient, or dMMR, rectal cancer with immunotherapy, which is dramatically changing the treatment landscape for these patients.]]></description><guid isPermaLink="false">a4c81d2f-8ad0-4536-a64c-1b3e91daebb7</guid><pubDate>Sun, 29 Jun 2025 23:33:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/67049521/404237355_44100_2_1fb8876ab0237.mp3" length="32213929" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4doKZ8x8WocSPejeZlun4Y/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we explored Total Neoadjuvant Therapy, or TNT, which has revolutionized the management of high-risk locally advanced rectal cancer by increasing pathologic complete response, or pCR, rates and improving distant control. These...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we explored Total Neoadjuvant Therapy, or TNT, which has revolutionized the management of high-risk locally advanced rectal cancer by increasing pathologic complete response, or pCR, rates and improving distant control. These impressive pCR rates have opened the door to one of the most exciting and debated topics in rectal cancer: avoiding major surgery through "Watch and Wait," or Non-Operative Management. Today, we dive deep into this organ-preserving approach, defining who is a candidate and what surveillance entails. We'll examine key trials like OPRA and data from the International Watch and Wait Database. Finally, we'll shift to a truly groundbreaking development: the highly effective management of mismatch repair deficient, or dMMR, rectal cancer with immunotherapy, which is dramatically changing the treatment landscape for these patients.]]></itunes:summary><itunes:duration>2014</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E17: Rectal Cancer Part 3: The TNT Revolution &amp; dMMR Management</title><link>https://www.spreaker.com/episode/g-i-e17-rectal-cancer-part-3-the-tnt-revolution-dmmr-management--66799870</link><description><![CDATA[In our last episode, we established the foundational principles of neoadjuvant radiation, proving that giving RT before surgery is superior and comparing the short-course and long-course approaches. That framework is perfect for standard-risk disease. But for patients with the highest-risk tumors, the primary driver of mortality isn't local failure—it's distant metastases.This reality has sparked a true revolution in rectal cancer care. Today, we dive into that revolution: Total Neoadjuvant Therapy, or TNT. We will define TNT and its rationale, dissect the blockbuster trials that have redefined the standard of care for high-risk rectal cancer, and cover the game-changing management for biologically distinct dMMR tumors.]]></description><guid isPermaLink="false">2aa76ff4-ef54-4e9f-b25b-4505e956a203</guid><pubDate>Sun, 29 Jun 2025 23:32:26 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66799870/403022519_44100_2_5eb101accb349.mp3" length="20888907" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7aZ70tmNC7pYtGkEswZSRu/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we established the foundational principles of neoadjuvant radiation, proving that giving RT before surgery is superior and comparing the short-course and long-course approaches. That framework is perfect for standard-risk disease....</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we established the foundational principles of neoadjuvant radiation, proving that giving RT before surgery is superior and comparing the short-course and long-course approaches. That framework is perfect for standard-risk disease. But for patients with the highest-risk tumors, the primary driver of mortality isn't local failure—it's distant metastases.This reality has sparked a true revolution in rectal cancer care. Today, we dive into that revolution: Total Neoadjuvant Therapy, or TNT. We will define TNT and its rationale, dissect the blockbuster trials that have redefined the standard of care for high-risk rectal cancer, and cover the game-changing management for biologically distinct dMMR tumors.]]></itunes:summary><itunes:duration>1306</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E16: Rectal Cancer Part 2: Neoadjuvant Foundations</title><link>https://www.spreaker.com/episode/g-i-e16-rectal-cancer-part-2-neoadjuvant-foundations--66799871</link><description><![CDATA[In our last episode, we established the fundamental clinical landscape of rectal cancer—the anatomy, the critical role of MRI in staging, and the surgical revolution of Total Mesorectal Excision. We learned that with high-quality TME, surgeons could dramatically reduce local recurrence. The question then became: could we improve upon this new surgical standard?]]></description><guid isPermaLink="false">d035dc6f-fc73-48c7-8d2d-8751dcaa825e</guid><pubDate>Sun, 29 Jun 2025 23:29:38 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66799871/403022330_44100_2_b127166daf76b.mp3" length="31281044" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6iZKnve9D8twbDAF5ilyuc/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we established the fundamental clinical landscape of rectal cancer—the anatomy, the critical role of MRI in staging, and the surgical revolution of Total Mesorectal Excision. We learned that with high-quality TME, surgeons could...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we established the fundamental clinical landscape of rectal cancer—the anatomy, the critical role of MRI in staging, and the surgical revolution of Total Mesorectal Excision. We learned that with high-quality TME, surgeons could dramatically reduce local recurrence. The question then became: could we improve upon this new surgical standard?]]></itunes:summary><itunes:duration>1955</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>16</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E15: Rectal Cancer Part 1: Anatomy, Staging, and the TME Revolution</title><link>https://www.spreaker.com/episode/g-i-e15-rectal-cancer-part-1-anatomy-staging-and-the-tme-revolution--66799873</link><description><![CDATA[If there is one disease site that perfectly illustrates the power of multidisciplinary, evidence-based cancer care, it’s rectal cancer. The evolution of its treatment is a masterclass in how surgery, radiation, and chemotherapy can be integrated to dramatically improve outcomes. But before we can appreciate that evolution, we must master the fundamentals.Today, we lay the groundwork for this entire story. We will use a classic case to walk through the essential workup, the critical anatomy that dictates treatment, modern staging with MRI, and finally, the surgical innovation that changed everything—Total Mesorectal Excision.]]></description><guid isPermaLink="false">0f856c4e-eaba-44b2-a527-cbb9c63ebf34</guid><pubDate>Sun, 29 Jun 2025 23:27:36 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66799873/403021884_44100_2_bf569c519f634.mp3" length="29207966" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3ofkWkZ5wVM2WwravV87qK/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>If there is one disease site that perfectly illustrates the power of multidisciplinary, evidence-based cancer care, it’s rectal cancer. The evolution of its treatment is a masterclass in how surgery, radiation, and chemotherapy can be integrated to...</itunes:subtitle><itunes:summary><![CDATA[If there is one disease site that perfectly illustrates the power of multidisciplinary, evidence-based cancer care, it’s rectal cancer. The evolution of its treatment is a masterclass in how surgery, radiation, and chemotherapy can be integrated to dramatically improve outcomes. But before we can appreciate that evolution, we must master the fundamentals.Today, we lay the groundwork for this entire story. We will use a classic case to walk through the essential workup, the critical anatomy that dictates treatment, modern staging with MRI, and finally, the surgical innovation that changed everything—Total Mesorectal Excision.]]></itunes:summary><itunes:duration>1826</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E14: Liver P3: Biliary Cancers &amp; Metastasis Management</title><link>https://www.spreaker.com/episode/g-i-e14-liver-p3-biliary-cancers-metastasis-management--66792873</link><description><![CDATA[Today, we conclude our liver mini-series by tackling these crucial topics.F irst, we’ll cover the evidence-based management for biliary tract cancers—including gallbladder cancer and cholangiocarcinoma—with a focus on the patterns of failure that guide our use of adjuvant radiation. Then, we’ll pivot to one of the most common clinical scenarios we face: treating colorectal liver metastases, discussing the role of SBRT in the context of other local therapies.]]></description><guid isPermaLink="false">63fbea35-c780-4135-92fb-5af7916a01ed</guid><pubDate>Sun, 29 Jun 2025 07:32:24 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66792873/402988081_44100_2_5c3601237a1a1.mp3" length="21202794" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/55LgNhdpWSw5fJXxFN0KGI/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we conclude our liver mini-series by tackling these crucial topics.F irst, we’ll cover the evidence-based management for biliary tract cancers—including gallbladder cancer and cholangiocarcinoma—with a focus on the patterns of failure that...</itunes:subtitle><itunes:summary><![CDATA[Today, we conclude our liver mini-series by tackling these crucial topics.F irst, we’ll cover the evidence-based management for biliary tract cancers—including gallbladder cancer and cholangiocarcinoma—with a focus on the patterns of failure that guide our use of adjuvant radiation. Then, we’ll pivot to one of the most common clinical scenarios we face: treating colorectal liver metastases, discussing the role of SBRT in the context of other local therapies.]]></itunes:summary><itunes:duration>1326</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>14</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E13: HCC Part 2: SBRT Workshop – Doses, Data &amp; No-Fly Zones</title><link>https://www.spreaker.com/episode/g-i-e13-hcc-part-2-sbrt-workshop-doses-data-no-fly-zones--66792872</link><description><![CDATA[Today, we conduct our SBRT masterclass for HCC. We will make the definitive case for SBRT over other local therapies by citing the key comparative data. We'll detail the evidence for treating high-risk disease like portal vein thrombosis and walk through the critical dosimetric details—ablative doses, the RTOG 1112 de-escalation schema, and the crucial constraints you need to know to treat safely and effectively.]]></description><guid isPermaLink="false">22b3b7bc-0cf5-4285-a6a5-a1e8356c6245</guid><pubDate>Sun, 29 Jun 2025 07:31:11 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66792872/402988058_44100_2_8345e0f273b35.mp3" length="31953122" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1rhyYeUYbBmFDuDuRPEoK8/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we conduct our SBRT masterclass for HCC. We will make the definitive case for SBRT over other local therapies by citing the key comparative data. We'll detail the evidence for treating high-risk disease like portal vein thrombosis and walk...</itunes:subtitle><itunes:summary><![CDATA[Today, we conduct our SBRT masterclass for HCC. We will make the definitive case for SBRT over other local therapies by citing the key comparative data. We'll detail the evidence for treating high-risk disease like portal vein thrombosis and walk through the critical dosimetric details—ablative doses, the RTOG 1112 de-escalation schema, and the crucial constraints you need to know to treat safely and effectively.]]></itunes:summary><itunes:duration>1997</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E12: HCC Part 1: The HCC Toolkit – Staging, IR, and Systemic Therapy</title><link>https://www.spreaker.com/episode/g-i-e12-hcc-part-1-the-hcc-toolkit-staging-ir-and-systemic-therapy--66792871</link><description><![CDATA[Welcome back to Rad Onc Smart Review, GI Series.T his is Episode 12: HCC Part 1: The HCC Toolkit – Staging, IR, and Systemic Therapy . Hepatocellular carcinoma, or HCC, is a unique beast in oncology. Unlike most cancers where our focus is solely on the tumor, in HCC we are fighting a war on two fronts: the cancer itself, and the often-diseased liver it inhabits. This dual challenge means that staging and treatment decisions are far more complex than just TNM. Today, we're opening up the HCC toolkit. We'll build a comprehensive framework for managing this disease, starting with the essential staging systems that integrate liver function, like BCLC and Child-Pugh. Then, we’ll tour the interventional radiology suite, comparing TACE, TARE, and RFA. Finally, we'll review the evolution of systemic therapy, from the disappointing early agents to the modern immunotherapy combinations that have transformed the field.]]></description><guid isPermaLink="false">49411893-b762-4011-9027-966b56c557e5</guid><pubDate>Sun, 29 Jun 2025 07:29:47 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66792871/402988024_44100_2_94e1b1bfa8a03.mp3" length="27763499" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7avovpuyxRpc9nNYP9MGue/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, GI Series.T his is Episode 12: HCC Part 1: The HCC Toolkit – Staging, IR, and Systemic Therapy . Hepatocellular carcinoma, or HCC, is a unique beast in oncology. Unlike most cancers where our focus is solely on...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, GI Series.T his is Episode 12: HCC Part 1: The HCC Toolkit – Staging, IR, and Systemic Therapy . Hepatocellular carcinoma, or HCC, is a unique beast in oncology. Unlike most cancers where our focus is solely on the tumor, in HCC we are fighting a war on two fronts: the cancer itself, and the often-diseased liver it inhabits. This dual challenge means that staging and treatment decisions are far more complex than just TNM. Today, we're opening up the HCC toolkit. We'll build a comprehensive framework for managing this disease, starting with the essential staging systems that integrate liver function, like BCLC and Child-Pugh. Then, we’ll tour the interventional radiology suite, comparing TACE, TARE, and RFA. Finally, we'll review the evolution of systemic therapy, from the disappointing early agents to the modern immunotherapy combinations that have transformed the field.]]></itunes:summary><itunes:duration>1736</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>12</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E11: Pancreas Part 4: Guideline, Planning &amp; Case-Based Review</title><link>https://www.spreaker.com/episode/g-i-e11-pancreas-part-4-guideline-planning-case-based-review--66782481</link><description><![CDATA[Over the last three episodes, we've journeyed through the complex evidence for pancreatic cancer. We’ve dissected the adjuvant debate, explored the neoadjuvant revolution, and held a masterclass on SBRT. Now, it’s time to put it all together. This is our synthesis episode, where we translate the data from landmark trials into practical, actionable plans.We will start by summarizing the key recommendations from the major guidelines. Then, we’ll move into a detailed treatment planning workshop, covering both postoperative conventional planning and modern SBRT. Finally, we'll work through a classic clinical dilemma to solidify your decision-making skills.]]></description><guid isPermaLink="false">9e27841d-c4ae-442a-9219-cd5c418e5dad</guid><pubDate>Sat, 28 Jun 2025 02:11:04 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782481/402946643_44100_2_7dbe15ed4a23.mp3" length="31589916" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Over the last three episodes, we've journeyed through the complex evidence for pancreatic cancer. We’ve dissected the adjuvant debate, explored the neoadjuvant revolution, and held a masterclass on SBRT. Now, it’s time to put it all together. This is...</itunes:subtitle><itunes:summary><![CDATA[Over the last three episodes, we've journeyed through the complex evidence for pancreatic cancer. We’ve dissected the adjuvant debate, explored the neoadjuvant revolution, and held a masterclass on SBRT. Now, it’s time to put it all together. This is our synthesis episode, where we translate the data from landmark trials into practical, actionable plans.We will start by summarizing the key recommendations from the major guidelines. Then, we’ll move into a detailed treatment planning workshop, covering both postoperative conventional planning and modern SBRT. Finally, we'll work through a classic clinical dilemma to solidify your decision-making skills.]]></itunes:summary><itunes:duration>1975</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>11</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E10: Pancreas Part 3: LAPC &amp; SBRT Masterclass</title><link>https://www.spreaker.com/episode/g-i-e10-pancreas-part-3-lapc-sbrt-masterclass--66782266</link><description><![CDATA[In our last two episodes, we focused on patients with resectable or borderline resectable pancreatic cancer—those for whom surgery is the ultimate goal. Today, we turn to a different, but equally challenging scenario: the patient with locally advanced, unresectable disease. These are the patients whose tumors are intimately involved with the major blood vessels, taking surgery off the table, but who do not yet have distant metastases. Here, the goals shift from cure to long-term control. This is where radiation therapy, particularly SBRT, has seen its most significant evolution. This is our SBRT masterclass: we’ll cover the data for conventional chemoradiation, justify ablative SBRT doses, and tackle the critical controversy of how to define our target volumes.]]></description><guid isPermaLink="false">52b1299a-32f3-4ff2-8352-e6d349eaeb8f</guid><pubDate>Sat, 28 Jun 2025 01:17:12 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782266/402945113_44100_2_4caa47d8889e4.mp3" length="19965635" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last two episodes, we focused on patients with resectable or borderline resectable pancreatic cancer—those for whom surgery is the ultimate goal. Today, we turn to a different, but equally challenging scenario: the patient with locally...</itunes:subtitle><itunes:summary><![CDATA[In our last two episodes, we focused on patients with resectable or borderline resectable pancreatic cancer—those for whom surgery is the ultimate goal. Today, we turn to a different, but equally challenging scenario: the patient with locally advanced, unresectable disease. These are the patients whose tumors are intimately involved with the major blood vessels, taking surgery off the table, but who do not yet have distant metastases. Here, the goals shift from cure to long-term control. This is where radiation therapy, particularly SBRT, has seen its most significant evolution. This is our SBRT masterclass: we’ll cover the data for conventional chemoradiation, justify ablative SBRT doses, and tackle the critical controversy of how to define our target volumes.]]></itunes:summary><itunes:duration>1248</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>10</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E09: Pancreas Part 2: The Neoadjuvant Revolution for Resectable &amp; Borderline Resectable Pancreatic Cancer</title><link>https://www.spreaker.com/episode/g-i-e09-pancreas-part-2-the-neoadjuvant-revolution-for-resectable-borderline-resectable-pancreatic-cancer--66782267</link><description><![CDATA[Welcome back to Rad Onc Smart Review, GI Series. In our last episode, we wrestled with the difficult data for adjuvant therapy, where even after a grueling Whipple procedure, the prognosis remains guarded. This reality has fueled one of the most significant paradigm shifts in modern GI oncology: moving therapy from the postoperative to the preoperative setting. The rationale is simple yet powerful: select the right patients, improve the quality of surgery, and deliver systemic therapy when patients are strongest. Today, we explore this neoadjuvant revolution. We’ll start by defining who is and who is not a surgical candidate based on the critical vascular anatomy. Then, we’ll dive into the landmark trials—PREOPANC-1 and Alliance A-0-2-1-5-0-1—that are shaping our current standards and fueling the ongoing debate.]]></description><guid isPermaLink="false">297e8af8-6d43-461b-98fd-c4e5d70d6b9e</guid><pubDate>Sat, 28 Jun 2025 01:10:12 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782267/402944928_44100_2_8fadf675d1e9.mp3" length="38006425" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, GI Series. In our last episode, we wrestled with the difficult data for adjuvant therapy, where even after a grueling Whipple procedure, the prognosis remains guarded. This reality has fueled one of the most...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, GI Series. In our last episode, we wrestled with the difficult data for adjuvant therapy, where even after a grueling Whipple procedure, the prognosis remains guarded. This reality has fueled one of the most significant paradigm shifts in modern GI oncology: moving therapy from the postoperative to the preoperative setting. The rationale is simple yet powerful: select the right patients, improve the quality of surgery, and deliver systemic therapy when patients are strongest. Today, we explore this neoadjuvant revolution. We’ll start by defining who is and who is not a surgical candidate based on the critical vascular anatomy. Then, we’ll dive into the landmark trials—PREOPANC-1 and Alliance A-0-2-1-5-0-1—that are shaping our current standards and fueling the ongoing debate.]]></itunes:summary><itunes:duration>2376</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>9</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E08: Pancreas Part 1: The Adjuvant Setting &amp; The Great RT Debate</title><link>https://www.spreaker.com/episode/g-i-e08-pancreas-part-1-the-adjuvant-setting-the-great-rt-debate--66782270</link><description><![CDATA[Welcome back to Rad Onc Smart Review, GI Series. Pancreatic cancer carries one of the most sobering prognoses in oncology. For the small fraction of patients who present with resectable disease, surgery offers the only hope for a cure. But even after a successful resection, the risk of recurrence is incredibly high, making effective adjuvant therapy a critical component of care. For decades, the question of "what to do after surgery" has been one of the most contentious debates in GI oncology, pitting aggressive systemic chemotherapy against the potential local control benefit of radiation.Today, we're going to trace this evolution. We’ll dissect the landmark trials that both built up and tore down the role of adjuvant radiation, and follow the rise of modern chemotherapy from single agents to the powerhouse regimens that are finally moving the survival needle.]]></description><guid isPermaLink="false">57d309f5-c7ef-4c3e-bf80-dacdd5eb1d02</guid><pubDate>Sat, 28 Jun 2025 01:05:16 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782270/402944785_44100_2_fdd161cd93788.mp3" length="31574033" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0hrcfWvKdYJFBKFc2ZAzvK/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, GI Series. Pancreatic cancer carries one of the most sobering prognoses in oncology. For the small fraction of patients who present with resectable disease, surgery offers the only hope for a cure. But even after...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, GI Series. Pancreatic cancer carries one of the most sobering prognoses in oncology. For the small fraction of patients who present with resectable disease, surgery offers the only hope for a cure. But even after a successful resection, the risk of recurrence is incredibly high, making effective adjuvant therapy a critical component of care. For decades, the question of "what to do after surgery" has been one of the most contentious debates in GI oncology, pitting aggressive systemic chemotherapy against the potential local control benefit of radiation.Today, we're going to trace this evolution. We’ll dissect the landmark trials that both built up and tore down the role of adjuvant radiation, and follow the rise of modern chemotherapy from single agents to the powerhouse regimens that are finally moving the survival needle.]]></itunes:summary><itunes:duration>1974</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>8</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E07: Gastric Cancer Part 2: Adjuvant RT, Targeted Therapy &amp; Planning</title><link>https://www.spreaker.com/episode/g-i-e07-gastric-cancer-part-2-adjuvant-rt-targeted-therapy-planning--66782271</link><description><![CDATA[In our last episode, we established that for resectable gastric cancer, high-quality D2 surgery and effective perioperative chemotherapy with FLOT is the modern standard of care. But that raises a critical question for us as radiation oncologists: what is the role of radiation therapy in this disease? Today, we answer that question by dissecting the landmark trials of adjuvant chemoradiation, exploring the use of targeted therapy for HER2-positive disease, and putting it all together in a practical treatment planning workshop.]]></description><guid isPermaLink="false">de3ecab3-f0b8-4bd1-b563-0aa2bb892f56</guid><pubDate>Sat, 28 Jun 2025 01:02:40 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782271/402944723_44100_2_bfaa18ed635e3.mp3" length="17543143" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2o8uIz9FBdGPaM89uYKufQ/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we established that for resectable gastric cancer, high-quality D2 surgery and effective perioperative chemotherapy with FLOT is the modern standard of care. But that raises a critical question for us as radiation oncologists:...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we established that for resectable gastric cancer, high-quality D2 surgery and effective perioperative chemotherapy with FLOT is the modern standard of care. But that raises a critical question for us as radiation oncologists: what is the role of radiation therapy in this disease? Today, we answer that question by dissecting the landmark trials of adjuvant chemoradiation, exploring the use of targeted therapy for HER2-positive disease, and putting it all together in a practical treatment planning workshop.]]></itunes:summary><itunes:duration>1097</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>7</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E06: Gastric Cancer Part 1, covering Surgery and Perioperative Chemotherapy</title><link>https://www.spreaker.com/episode/g-i-e06-gastric-cancer-part-1-covering-surgery-and-perioperative-chemotherapy--66782269</link><description><![CDATA[Welcome back to Rad Onc Smart Review, where we break down the clinical decisions that matter most in radiation oncology. This is Episode six: Gastric Cancer Part one, covering Surgery and Perioperative Chemotherapy.Gastric cancer remains a major global health challenge. While less common in the United States, it’s the third leading cause of cancer-related death worldwide, often because it's diagnosed at an advanced stage. For decades, the management of resectable disease has been an evolving story, a tug-of-war between more aggressive surgery and more effective systemic therapy. Today, we're going to trace that evolution, starting with the fundamentals of surgical resection and nodal dissection, and then walking through the landmark trials that established and then redefined the standard for perioperative chemotherapy.]]></description><guid isPermaLink="false">bb1bbb3d-d2ee-4a1c-ad0c-4c2d1c49c2e0</guid><pubDate>Sat, 28 Jun 2025 00:59:04 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782269/402944647_44100_2_135fba0cbe00d.mp3" length="31719065" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0kpXFSI2ppCC9xjOkckezz/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, where we break down the clinical decisions that matter most in radiation oncology. This is Episode six: Gastric Cancer Part one, covering Surgery and Perioperative Chemotherapy.Gastric cancer remains a major...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, where we break down the clinical decisions that matter most in radiation oncology. This is Episode six: Gastric Cancer Part one, covering Surgery and Perioperative Chemotherapy.Gastric cancer remains a major global health challenge. While less common in the United States, it’s the third leading cause of cancer-related death worldwide, often because it's diagnosed at an advanced stage. For decades, the management of resectable disease has been an evolving story, a tug-of-war between more aggressive surgery and more effective systemic therapy. Today, we're going to trace that evolution, starting with the fundamentals of surgical resection and nodal dissection, and then walking through the landmark trials that established and then redefined the standard for perioperative chemotherapy.]]></itunes:summary><itunes:duration>1983</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>6</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E05: Esophagus Part 4: NOM, Advanced Disease &amp; Treatment Planning</title><link>https://www.spreaker.com/episode/g-i-e05-esophagus-part-4-nom-advanced-disease-treatment-planning--66782273</link><description><![CDATA[This is Episode 05: Esophagus Part 4: NOM, Advanced Disease &amp; Treatment Planning.This is our capstone episode on esophageal cancer. We’ve covered the fundamentals, the landmark trials, and the modern debates. Today, we bring it all together. We’ll explore the exciting frontier of non-operative management, clarify the algorithm for using immunotherapy in advanced disease, and then roll up our sleeves for a practical treatment planning workshop where we’ll delineate volumes and apply critical dose constraints based on the latest evidence.]]></description><guid isPermaLink="false">aea56246-090b-4dd4-8674-adeae58f9c15</guid><pubDate>Sat, 28 Jun 2025 00:57:25 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782273/402944603_44100_2_54f2bac8d0295.mp3" length="33220374" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1Pvl6Cz0De3YxvaJjuJOU1/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 05: Esophagus Part 4: NOM, Advanced Disease &amp;amp; Treatment Planning.This is our capstone episode on esophageal cancer. We’ve covered the fundamentals, the landmark trials, and the modern debates. Today, we bring it all together. We’ll...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 05: Esophagus Part 4: NOM, Advanced Disease &amp; Treatment Planning.This is our capstone episode on esophageal cancer. We’ve covered the fundamentals, the landmark trials, and the modern debates. Today, we bring it all together. We’ll explore the exciting frontier of non-operative management, clarify the algorithm for using immunotherapy in advanced disease, and then roll up our sleeves for a practical treatment planning workshop where we’ll delineate volumes and apply critical dose constraints based on the latest evidence.]]></itunes:summary><itunes:duration>2077</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>5</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E04: Esophagus Part 3: The Dose Escalation &amp; Adjuvant IO</title><link>https://www.spreaker.com/episode/g-i-e04-esophagus-part-3-the-dose-escalation-adjuvant-io--66782272</link><description><![CDATA[This is Episode 04: Esophagus Part 3: The Dose Escalation &amp; Adjuvant IO Debates.In our last episode, we laid the foundation with the landmark trials establishing neoadjuvant and definitive chemoradiation. But a key principle in oncology is to always ask: can we do better? Today, we tackle the controversies and innovations that have attempted to improve upon those standards. We’ll dissect the decades-long, and largely disappointing, quest for dose escalation. Then, we’ll pivot to the modern era and explore how adjuvant immunotherapy is revolutionizing outcomes.]]></description><guid isPermaLink="false">295b04dc-cda0-421d-8981-9e267eada19f</guid><pubDate>Sat, 28 Jun 2025 00:55:04 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782272/402944529_44100_2_42dd3661dd1a.mp3" length="22287398" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7ugM5xCeiE0nQy7KO0Y2Q5/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 04: Esophagus Part 3: The Dose Escalation &amp;amp; Adjuvant IO Debates.In our last episode, we laid the foundation with the landmark trials establishing neoadjuvant and definitive chemoradiation. But a key principle in oncology is to...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 04: Esophagus Part 3: The Dose Escalation &amp; Adjuvant IO Debates.In our last episode, we laid the foundation with the landmark trials establishing neoadjuvant and definitive chemoradiation. But a key principle in oncology is to always ask: can we do better? Today, we tackle the controversies and innovations that have attempted to improve upon those standards. We’ll dissect the decades-long, and largely disappointing, quest for dose escalation. Then, we’ll pivot to the modern era and explore how adjuvant immunotherapy is revolutionizing outcomes.]]></itunes:summary><itunes:duration>1393</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>4</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E03: Esophagus Part 2: Neoadjuvant &amp; Definitive CCRT</title><link>https://www.spreaker.com/episode/g-i-e03-esophagus-part-2-neoadjuvant-definitive-ccrt--66782274</link><description><![CDATA[This is Episode 03: Esophagus Part 2: Neoadjuvant &amp; Definitive CCRT.In our last episode, we laid the groundwork for esophageal cancer management. Now, we move to the heart of the matter: how we treat locally advanced disease. This episode is all about the landmark trials that defined the role of chemoradiation. We'll dissect the two pillars of modern esophageal radiation oncology: RTOG eighty-five-zero-one for definitive treatment, and the CROSS trial for the neoadjuvant setting. We’ll then see how these standards are being challenged by newer chemotherapy regimens.]]></description><guid isPermaLink="false">94d4a5b8-b286-4307-a5a4-eeeb36486007</guid><pubDate>Sat, 28 Jun 2025 00:49:15 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782274/402944385_44100_2_23c74b4aace79.mp3" length="23695503" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/47YSUBCTZDnG0BNS3v4aFx/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 03: Esophagus Part 2: Neoadjuvant &amp;amp; Definitive CCRT.In our last episode, we laid the groundwork for esophageal cancer management. Now, we move to the heart of the matter: how we treat locally advanced disease. This episode is all...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 03: Esophagus Part 2: Neoadjuvant &amp; Definitive CCRT.In our last episode, we laid the groundwork for esophageal cancer management. Now, we move to the heart of the matter: how we treat locally advanced disease. This episode is all about the landmark trials that defined the role of chemoradiation. We'll dissect the two pillars of modern esophageal radiation oncology: RTOG eighty-five-zero-one for definitive treatment, and the CROSS trial for the neoadjuvant setting. We’ll then see how these standards are being challenged by newer chemotherapy regimens.]]></itunes:summary><itunes:duration>1481</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>3</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E02: Esophagus Part 1: Anatomy, Staging &amp; Surgical Options</title><link>https://www.spreaker.com/episode/g-i-e02-esophagus-part-1-anatomy-staging-surgical-options--66782276</link><description><![CDATA[This is Episode 02: Esophagus Part 1: Anatomy, Staging &amp; Surgical Options.Getting the fundamentals right in esophageal cancer is everything. It's a disease where anatomy dictates treatment fields, staging dictates modality, and surgical approach dictates potential toxicities. Today, we'll build that crucial foundation, covering the anatomy and workup that drive our initial decisions, the nuances of the latest AJCC staging, and the surgical landscape before we even think about turning on the beam.]]></description><guid isPermaLink="false">f02f83f1-006d-464a-9911-31d98be9405e</guid><pubDate>Sat, 28 Jun 2025 00:41:24 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782276/402944212_44100_2_4166c063d7cbf.mp3" length="28247078" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7GQEwMdWYzVxD5OZ3g04cV/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 02: Esophagus Part 1: Anatomy, Staging &amp;amp; Surgical Options.Getting the fundamentals right in esophageal cancer is everything. It's a disease where anatomy dictates treatment fields, staging dictates modality, and surgical approach...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 02: Esophagus Part 1: Anatomy, Staging &amp; Surgical Options.Getting the fundamentals right in esophageal cancer is everything. It's a disease where anatomy dictates treatment fields, staging dictates modality, and surgical approach dictates potential toxicities. Today, we'll build that crucial foundation, covering the anatomy and workup that drive our initial decisions, the nuances of the latest AJCC staging, and the surgical landscape before we even think about turning on the beam.]]></itunes:summary><itunes:duration>1766</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>2</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>G.I. E01: Principles: Re-RT, Toxicity, &amp; Contouring Rare Sites</title><link>https://www.spreaker.com/episode/g-i-e01-principles-re-rt-toxicity-contouring-rare-sites--66782275</link><description><![CDATA[Welcome back to Rad Onc Smart Review, G.I. Oncology Edition. This is Episode 01: GI Principles: Re-RT, Toxicity, &amp; Contouring Rare Sites.Before we dive deep into specific GI malignancies, we’re going to build a strong foundation. This episode covers four high-yield topics that cut across multiple disease sites: re-irradiation of the pelvis, management of chronic radiation proctitis, contouring inguinal nodes, and treating adrenal metastases. Mastering these principles will set you up for success throughout our entire GI series.]]></description><guid isPermaLink="false">43479732-2660-44a3-826d-363579027e10</guid><pubDate>Sat, 28 Jun 2025 00:38:49 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66782275/402944143_44100_2_46e48e6c3f5ee.mp3" length="26265534" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5Nkg52gd4foxQNDR1NbvlE/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, G.I. Oncology Edition. This is Episode 01: GI Principles: Re-RT, Toxicity, &amp;amp; Contouring Rare Sites.Before we dive deep into specific GI malignancies, we’re going to build a strong foundation. This episode...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, G.I. Oncology Edition. This is Episode 01: GI Principles: Re-RT, Toxicity, &amp; Contouring Rare Sites.Before we dive deep into specific GI malignancies, we’re going to build a strong foundation. This episode covers four high-yield topics that cut across multiple disease sites: re-irradiation of the pelvis, management of chronic radiation proctitis, contouring inguinal nodes, and treating adrenal metastases. Mastering these principles will set you up for success throughout our entire GI series.]]></itunes:summary><itunes:duration>1642</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/0160548cc47237d6379c2b919f847864.jpg"/><itunes:season>3</itunes:season><itunes:episode>1</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E39C: Radbio Calculations 1: Quantifying Cell Survival</title><link>https://www.spreaker.com/episode/radbio-e39c-radbio-calculations-1-quantifying-cell-survival--66679382</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 39C in our special series on Radiobiology Calculations. Today, we’re tackling the mathematics that underpins the very foundation of modern radiation therapy: fractionation. Why do we give many small doses of radiation instead of one big one? The answer lies in the numbers, and mastering these calculations is essential for both your board exams and for safe, effective clinical practice.]]></description><guid isPermaLink="false">4f70586e-0d3b-41e7-856b-3f9e9a329a93</guid><pubDate>Sat, 21 Jun 2025 18:54:36 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66679382/402572840_44100_2_aca1db41b62cc.mp3" length="37924087" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5QmWVyj9b8hpSIzxOkHaot/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is Episode 39C in our special series on Radiobiology Calculations. Today, we’re tackling the mathematics that underpins the very foundation of modern radiation therapy: fractionation. Why do we give many...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 39C in our special series on Radiobiology Calculations. Today, we’re tackling the mathematics that underpins the very foundation of modern radiation therapy: fractionation. Why do we give many small doses of radiation instead of one big one? The answer lies in the numbers, and mastering these calculations is essential for both your board exams and for safe, effective clinical practice.]]></itunes:summary><itunes:duration>2371</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>39</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E39B: Radbio Calculations 2 Tumor Control &amp; Kinetics</title><link>https://www.spreaker.com/episode/radbio-e39b-radbio-calculations-2-tumor-control-kinetics--66678646</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 39B, the second installment of our special series on Radiobiology Calculations. Today, our focus is on Tumor Control &amp; Kinetics. In our last episode, we mastered the calculations for cell survival on a microscopic level. Now, we're scaling up to the macroscopic world of clinical tumors. We'll start by calculating the massive radiation doses required to eradicate billions of tumor cells, connecting this to the concept of Tumor Control Probability, or TCP. We'll then shift gears to explore the dynamics of tumor growth, learning how to relate a tumor's change in size to its underlying cell doublings and how factors like cell loss influence its growth rate.]]></description><guid isPermaLink="false">2ae97fed-d8da-488a-972e-8e26ad74defb</guid><pubDate>Sat, 21 Jun 2025 18:17:41 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66678646/402571706_44100_2_146a6217f6fd5.mp3" length="22605465" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is Episode 39B, the second installment of our special series on Radiobiology Calculations. Today, our focus is on Tumor Control &amp;amp; Kinetics. In our last episode, we mastered the calculations for cell...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 39B, the second installment of our special series on Radiobiology Calculations. Today, our focus is on Tumor Control &amp; Kinetics. In our last episode, we mastered the calculations for cell survival on a microscopic level. Now, we're scaling up to the macroscopic world of clinical tumors. We'll start by calculating the massive radiation doses required to eradicate billions of tumor cells, connecting this to the concept of Tumor Control Probability, or TCP. We'll then shift gears to explore the dynamics of tumor growth, learning how to relate a tumor's change in size to its underlying cell doublings and how factors like cell loss influence its growth rate.]]></itunes:summary><itunes:duration>1413</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>39</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E39A: Radbio Calculations 1: Quantifying Cell Survival</title><link>https://www.spreaker.com/episode/radbio-e39a-radbio-calculations-1-quantifying-cell-survival--66678647</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 39A, and the first in our special series on Radiobiology Calculations. In this episode, Calculations 1: Quantifying Cell Survival, we're moving beyond concepts and getting our hands dirty with the numbers. We'll start with the foundational laboratory data from clonogenic assays and walk step-by-step through calculating Plating Efficiency and Surviving Fraction. Then, we'll master how to apply the Linear-Quadratic model for both acute and low-dose-rate exposures, touch on the classic Target Theory model, and finish with the essential conversion between D₀ and D₁₀.]]></description><guid isPermaLink="false">a3c34385-a3a7-406a-a46b-86b6fec8feb5</guid><pubDate>Sat, 21 Jun 2025 18:00:39 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66678647/402571159_44100_2_6ce75547baca7.mp3" length="46621818" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1zVWtsZKxPyZDYJu0Jt253/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is Episode 39A, and the first in our special series on Radiobiology Calculations. In this episode, Calculations 1: Quantifying Cell Survival, we're moving beyond concepts and getting our hands dirty with the...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 39A, and the first in our special series on Radiobiology Calculations. In this episode, Calculations 1: Quantifying Cell Survival, we're moving beyond concepts and getting our hands dirty with the numbers. We'll start with the foundational laboratory data from clonogenic assays and walk step-by-step through calculating Plating Efficiency and Surviving Fraction. Then, we'll master how to apply the Linear-Quadratic model for both acute and low-dose-rate exposures, touch on the classic Target Theory model, and finish with the essential conversion between D₀ and D₁₀.]]></itunes:summary><itunes:duration>2914</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>39</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E18C: RadOnc Board Exam Physics: Essential Review</title><link>https://www.spreaker.com/episode/radphysics-e18c-radonc-board-exam-physics-essential-review--66512412</link><description><![CDATA[Today, we're doing a rapid-fire, high-yield review of the absolute must-know concepts, formulas, and numbers for your board exams. We'll move quickly through seven key domains, from fundamental physics to advanced modalities and safety guidelines. Let's begin.]]></description><guid isPermaLink="false">af537974-5b22-4b53-8394-9093f2e49645</guid><pubDate>Wed, 11 Jun 2025 17:26:51 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66512412/401991551_44100_2_da990d5a39ab.mp3" length="37822941" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3XqVnEUBCsk7jxHszHxoqd/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Today, we're doing a rapid-fire, high-yield review of the absolute must-know concepts, formulas, and numbers for your board exams. We'll move quickly through seven key domains, from fundamental physics to advanced modalities and safety guidelines....</itunes:subtitle><itunes:summary><![CDATA[Today, we're doing a rapid-fire, high-yield review of the absolute must-know concepts, formulas, and numbers for your board exams. We'll move quickly through seven key domains, from fundamental physics to advanced modalities and safety guidelines. Let's begin.]]></itunes:summary><itunes:duration>2364</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E18B:Radiation Physics overview part 2</title><link>https://www.spreaker.com/episode/radphysics-e18b-radiation-physics-overview-part-2--66618059</link><description><![CDATA[Welcome back to our deep dive on the core principles of radiation physics. This is Part B of our comprehensive physics review. In Part A, we built the foundation, exploring everything from the atom and radioactive decay to the complex machines that generate our clinical beams.Exactly. We covered the "what" of radiation. Now, in this episode, we're going to cover the "how." We'll see how we measure, plan, and deliver dose with these beams. We'll get into dosimetry, M.U. calculations, advanced techniques like I.M.R.T. and V mat, and wrap up with crucial concepts in imaging and safety.]]></description><guid isPermaLink="false">24c0390f-dd41-4345-81bb-7ab3da6dbc03</guid><pubDate>Wed, 11 Jun 2025 05:30:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66618059/402429645_44100_2_9b54030a15b2a.mp3" length="57980694" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2yJYjsInpZm9SsiqwYpPlX/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to our deep dive on the core principles of radiation physics. This is Part B of our comprehensive physics review. In Part A, we built the foundation, exploring everything from the atom and radioactive decay to the complex machines that...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to our deep dive on the core principles of radiation physics. This is Part B of our comprehensive physics review. In Part A, we built the foundation, exploring everything from the atom and radioactive decay to the complex machines that generate our clinical beams.Exactly. We covered the "what" of radiation. Now, in this episode, we're going to cover the "how." We'll see how we measure, plan, and deliver dose with these beams. We'll get into dosimetry, M.U. calculations, advanced techniques like I.M.R.T. and V mat, and wrap up with crucial concepts in imaging and safety.]]></itunes:summary><itunes:duration>3624</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E18B: Physics overview</title><link>https://www.spreaker.com/episode/radphysics-e18b-physics-overview--66502620</link><description><![CDATA[Part 2 of physics overview]]></description><guid isPermaLink="false">79bf05bd-2420-4538-bd30-8c3834d4336b</guid><pubDate>Wed, 11 Jun 2025 02:22:48 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66502620/401949913_44100_2_1a571b4c6c4d9.mp3" length="60371839" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Part 2 of physics overview</itunes:subtitle><itunes:summary><![CDATA[Part 2 of physics overview]]></itunes:summary><itunes:duration>3774</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E18: Physics overview</title><link>https://www.spreaker.com/episode/radphysics-e18-physics-overview--66498637</link><description><![CDATA[Physics overview touching a little of every topic...work in progress.]]></description><guid isPermaLink="false">95cd9de8-fb4b-4a4c-a4b4-b9986652abdd</guid><pubDate>Tue, 10 Jun 2025 18:53:15 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66498637/401927472_44100_2_3df8868fa877b.mp3" length="109157289" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Physics overview touching a little of every topic...work in progress.</itunes:subtitle><itunes:summary><![CDATA[Physics overview touching a little of every topic...work in progress.]]></itunes:summary><itunes:duration>6823</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E17D: Lungs, Seeds, and Safety Shields</title><link>https://www.spreaker.com/episode/radphysics-e17d-lungs-seeds-and-safety-shields--66458841</link><description><![CDATA[This is our final episode focused purely on calculations! We've journeyed from basic decay to complex Monitor Unit calculations. Today, we hit the advanced scenarios: What happens when the beam hits lung or bone? How do we compare radically different fractionation schemes biologically? How does modern brachytherapy dosimetry really work with TG 43? And finally, the essential math for keeping everyone safe from radiation. Today, we’re calculating radiological path length, BED and EQD 2, applying the TG 43 framework with Air Kerma Strength, and ensuring our shielding calculations meet regulatory limits.]]></description><guid isPermaLink="false">ac82c255-dc3d-4b1c-b9d1-30f742e9163f</guid><pubDate>Sun, 08 Jun 2025 05:48:57 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66458841/401766930_44100_2_9d57f6e147aa2.mp3" length="51812453" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7zLGX7sKBpePR5Y6wpnnIJ/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is our final episode focused purely on calculations! We've journeyed from basic decay to complex Monitor Unit calculations. Today, we hit the advanced scenarios: What happens when the beam hits lung or bone? How do we compare radically different...</itunes:subtitle><itunes:summary><![CDATA[This is our final episode focused purely on calculations! We've journeyed from basic decay to complex Monitor Unit calculations. Today, we hit the advanced scenarios: What happens when the beam hits lung or bone? How do we compare radically different fractionation schemes biologically? How does modern brachytherapy dosimetry really work with TG 43? And finally, the essential math for keeping everyone safe from radiation. Today, we’re calculating radiological path length, BED and EQD 2, applying the TG 43 framework with Air Kerma Strength, and ensuring our shielding calculations meet regulatory limits.]]></itunes:summary><itunes:duration>3239</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E17C: Dose Divers and Electron Escapades</title><link>https://www.spreaker.com/episode/radphysics-e17c-dose-divers-and-electron-escapades--66456043</link><description><![CDATA[Welcome back to Radiation Oncology Smart Review – Calculation Toolkit Episode 17C: Dose Divers and Electron Escapades. Last time, we calibrated our detectors and nailed Monitor Unit calculations for standard setups. Now, we follow the dose after it leaves the machine head. Today, we'll master transferring dose between different depths using Percent Depth Doses and Tissue Maximum Ratios, untangle the geometric puzzles of skin gaps for field matching, learn the simple scaling rules for field sizes, calculate equivalent squares, and dip our toes into the unique world of electron beam Monitor Unit calculations.]]></description><guid isPermaLink="false">2427e45e-f7af-4365-a909-8ecbbc17e6c7</guid><pubDate>Sun, 08 Jun 2025 03:01:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66456043/401766805_44100_2_bc8a309805bf3.mp3" length="47927104" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/51E2GVmxoavOMBmH0rUiXm/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Radiation Oncology Smart Review – Calculation Toolkit Episode 17C: Dose Divers and Electron Escapades. Last time, we calibrated our detectors and nailed Monitor Unit calculations for standard setups. Now, we follow the dose after it...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Radiation Oncology Smart Review – Calculation Toolkit Episode 17C: Dose Divers and Electron Escapades. Last time, we calibrated our detectors and nailed Monitor Unit calculations for standard setups. Now, we follow the dose after it leaves the machine head. Today, we'll master transferring dose between different depths using Percent Depth Doses and Tissue Maximum Ratios, untangle the geometric puzzles of skin gaps for field matching, learn the simple scaling rules for field sizes, calculate equivalent squares, and dip our toes into the unique world of electron beam Monitor Unit calculations.]]></itunes:summary><itunes:duration>2996</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E17B: Dosimetry Detectives and Chamber Charades</title><link>https://www.spreaker.com/episode/radphysics-e17b-dosimetry-detectives-and-chamber-charades--66456039</link><description><![CDATA[Welcome back to Radiation Oncology Smart Review – Episode 17 part B: Dosimetry Detectives and Chamber Charades. Last time, we tackled the ticking clocks of decay and permanent implants. Today, we put on our detective hats to investigate how we actually measure radiation and make sure the right dose goes to the right place. We’ll decode the secrets of ion chambers and their sneaky temperature-pressure dependence, master the Monitor Unit, or M U, calculations for both S A D and S S D setups – the absolute bedrock of clinical physics – figure out how dose changes with depth using P D Ds and T M Rs, and learn how linacs play geometric tricks with field sizes.]]></description><guid isPermaLink="false">e30a6640-69bd-49f6-88e0-ec073b222b1e</guid><pubDate>Sun, 08 Jun 2025 03:00:50 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66456039/401766762_44100_2_bbd208a12c0c1.mp3" length="35321037" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2JbnRyRwv0D4pN9f183KRy/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Radiation Oncology Smart Review – Episode 17 part B: Dosimetry Detectives and Chamber Charades. Last time, we tackled the ticking clocks of decay and permanent implants. Today, we put on our detective hats to investigate how we...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Radiation Oncology Smart Review – Episode 17 part B: Dosimetry Detectives and Chamber Charades. Last time, we tackled the ticking clocks of decay and permanent implants. Today, we put on our detective hats to investigate how we actually measure radiation and make sure the right dose goes to the right place. We’ll decode the secrets of ion chambers and their sneaky temperature-pressure dependence, master the Monitor Unit, or M U, calculations for both S A D and S S D setups – the absolute bedrock of clinical physics – figure out how dose changes with depth using P D Ds and T M Rs, and learn how linacs play geometric tricks with field sizes.]]></itunes:summary><itunes:duration>2208</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E17a: Calculations 1: Half-Lives and Seed Sleuths</title><link>https://www.spreaker.com/episode/radphysics-e17a-calculations-1-half-lives-and-seed-sleuths--66456049</link><description><![CDATA[Welcome back to Radiation Oncology Smart Review – the targeted prep for your radiation oncology boards! I’m your guide, diving deep into the calculations that matter. This is Episode 17a of our Calculation Toolkit series, titled Radiation Oncology Calculations 1: Half-Lives and Seed Sleuths. Today we’ll master three bread-and-butter RAPHEX problem families: first, radioactive decay and time-activity puzzles, second, effective half-life mash-ups, and third, permanent implant total-dose questions. By the end you’ll know why lambda keeps physicists up at night, how to find the Goldilocks half-life combining body and physics, and how one sleepy iodine one twenty-five seed still manages to deliver its full punch over months.]]></description><guid isPermaLink="false">365156f7-2283-4d30-b2fb-6a43ec15b7d7</guid><pubDate>Sun, 08 Jun 2025 02:58:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66456049/401766739_44100_2_9178c898881cb.mp3" length="31120130" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2KZLeODVrYIbd0PpR9GKxS/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Radiation Oncology Smart Review – the targeted prep for your radiation oncology boards! I’m your guide, diving deep into the calculations that matter. This is Episode 17a of our Calculation Toolkit series, titled Radiation Oncology...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Radiation Oncology Smart Review – the targeted prep for your radiation oncology boards! I’m your guide, diving deep into the calculations that matter. This is Episode 17a of our Calculation Toolkit series, titled Radiation Oncology Calculations 1: Half-Lives and Seed Sleuths. Today we’ll master three bread-and-butter RAPHEX problem families: first, radioactive decay and time-activity puzzles, second, effective half-life mash-ups, and third, permanent implant total-dose questions. By the end you’ll know why lambda keeps physicists up at night, how to find the Goldilocks half-life combining body and physics, and how one sleepy iodine one twenty-five seed still manages to deliver its full punch over months.]]></itunes:summary><itunes:duration>1945</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E16c: PET &amp; Ultrasound Physics for RadOnc</title><link>https://www.spreaker.com/episode/radphysics-e16c-pet-ultrasound-physics-for-radonc--66447769</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series for our concluding episode! In P16b, we explored the crucial planning modalities of CT and MRI. Today, in Episode P16c: PET &amp; Ultrasound Physics for RadOnc, we round out our imaging tour by looking at two other important technologies: Positron Emission Tomography (PET), which gives us insights into metabolic function, and Ultrasound (US), often used for real-time guidance and visualizing certain structures.]]></description><guid isPermaLink="false">cdc61978-37d7-4267-95ec-0135affcbc6a</guid><pubDate>Sat, 07 Jun 2025 20:11:11 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66447769/401756586_44100_2_2e5de8795011f.mp3" length="33874063" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1ysNZRUwAOKn1eBPWnQ3N2/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series for our concluding episode! In P16b, we explored the crucial planning modalities of CT and MRI. Today, in Episode P16c: PET &amp;amp; Ultrasound Physics for RadOnc, we round out our imaging tour by...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series for our concluding episode! In P16b, we explored the crucial planning modalities of CT and MRI. Today, in Episode P16c: PET &amp; Ultrasound Physics for RadOnc, we round out our imaging tour by looking at two other important technologies: Positron Emission Tomography (PET), which gives us insights into metabolic function, and Ultrasound (US), often used for real-time guidance and visualizing certain structures.]]></itunes:summary><itunes:duration>2118</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>16</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E16b: CT &amp; MRI Physics for RadOnc</title><link>https://www.spreaker.com/episode/radphysics-e16b-ct-mri-physics-for-radonc--66447768</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P16a, we covered the crucial principles of radiation protection and the regulations governing our field. Now, in Episode P16b: CT &amp; MRI Physics for RadOnc, we dive into the physics behind the two imaging modalities most fundamental to treatment planning: Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). How do they create the detailed anatomical images we rely on every day?]]></description><guid isPermaLink="false">0c488a83-b7b0-404b-a086-e815ae7e48f1</guid><pubDate>Sat, 07 Jun 2025 20:09:54 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66447768/401756466_44100_2_e75203b84143c.mp3" length="49033860" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0wLYHM8iT36eDeoREjwBcl/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P16a, we covered the crucial principles of radiation protection and the regulations governing our field. Now, in Episode P16b: CT &amp;amp; MRI Physics for RadOnc, we dive into the physics behind...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P16a, we covered the crucial principles of radiation protection and the regulations governing our field. Now, in Episode P16b: CT &amp; MRI Physics for RadOnc, we dive into the physics behind the two imaging modalities most fundamental to treatment planning: Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). How do they create the detailed anatomical images we rely on every day?]]></itunes:summary><itunes:duration>3065</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>16</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E16a: Radiation Protection &amp; Regulations</title><link>https://www.spreaker.com/episode/radphysics-e16a-radiation-protection-regulations--66447770</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've explored how radiation is produced, how it interacts, how we measure it, plan treatments, and ensure quality. Now, we circle back to a fundamental responsibility: radiation safety. In Episode P16a: Radiation Protection &amp; Regulations, we'll review the types of radiation effects, the quantities used to measure risk (Dose Equivalent, Effective Dose), the ALARA principle, the critical regulatory dose limits for workers and the public, and touch upon managing dose from internal radioactivity.]]></description><guid isPermaLink="false">63685962-8d10-4dd3-a242-1c4fd42cd34f</guid><pubDate>Sat, 07 Jun 2025 19:38:56 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66447770/401755607_44100_2_156c5f66c3067.mp3" length="52224143" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/35tghcNbt2Ze2tkzNaSL8H/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! We've explored how radiation is produced, how it interacts, how we measure it, plan treatments, and ensure quality. Now, we circle back to a fundamental responsibility: radiation safety. In...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've explored how radiation is produced, how it interacts, how we measure it, plan treatments, and ensure quality. Now, we circle back to a fundamental responsibility: radiation safety. In Episode P16a: Radiation Protection &amp; Regulations, we'll review the types of radiation effects, the quantities used to measure risk (Dose Equivalent, Effective Dose), the ALARA principle, the critical regulatory dose limits for workers and the public, and touch upon managing dose from internal radioactivity.]]></itunes:summary><itunes:duration>3264</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>16</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E15c: Brachytherapy QA, Safety &amp; Regulations</title><link>https://www.spreaker.com/episode/radphysics-e15c-brachytherapy-qa-safety-regulations--66433165</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In E15a, we covered brachytherapy sources and TG-43 dose calculations. In P15b, we looked at clinical applications and planning systems. Now, in our final brachytherapy episode, P15c: Brachytherapy QA, Safety &amp; Regulations, we focus on arguably the most critical aspect: ensuring these procedures are performed safely and accurately, protecting both patients and staff, and complying with strict regulatory requirements.]]></description><guid isPermaLink="false">0b2eb889-4394-472d-a2f0-d316bfddb37a</guid><pubDate>Sat, 07 Jun 2025 04:36:42 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66433165/401732835_44100_2_4d5739e98646.mp3" length="50636316" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/23ywGpkG6HXHQuwcHt8Hdv/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In E15a, we covered brachytherapy sources and TG-43 dose calculations. In P15b, we looked at clinical applications and planning systems. Now, in our final brachytherapy episode, P15c:...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In E15a, we covered brachytherapy sources and TG-43 dose calculations. In P15b, we looked at clinical applications and planning systems. Now, in our final brachytherapy episode, P15c: Brachytherapy QA, Safety &amp; Regulations, we focus on arguably the most critical aspect: ensuring these procedures are performed safely and accurately, protecting both patients and staff, and complying with strict regulatory requirements.]]></itunes:summary><itunes:duration>3165</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E15b: Brachytherapy Applications, Systems &amp; Planning Concepts</title><link>https://www.spreaker.com/episode/radphysics-e15b-brachytherapy-applications-systems-planning-concepts--66433166</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P15a, we laid the groundwork for brachytherapy, focusing on the radioactive sources, how their strength is quantified using Air Kerma Strength (SK), and the details of the TG-43 dose calculation formalism. Now, in Episode P15b: Brachytherapy Applications, Systems &amp; Planning Concepts, we'll explore how these sources are actually used clinically – looking at intracavitary vs interstitial techniques, historical planning systems, and specific dose points like ICRU 38's Points A and B.]]></description><guid isPermaLink="false">d9cb8cac-c014-4bf5-b437-03b6f125c25d</guid><pubDate>Sat, 07 Jun 2025 04:33:54 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66433166/401732764_44100_2_3f7fba2486101.mp3" length="52626219" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1SalRSyMaLnDsNzlHjfxS5/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P15a, we laid the groundwork for brachytherapy, focusing on the radioactive sources, how their strength is quantified using Air Kerma Strength (SK), and the details of the TG-43 dose...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P15a, we laid the groundwork for brachytherapy, focusing on the radioactive sources, how their strength is quantified using Air Kerma Strength (SK), and the details of the TG-43 dose calculation formalism. Now, in Episode P15b: Brachytherapy Applications, Systems &amp; Planning Concepts, we'll explore how these sources are actually used clinically – looking at intracavitary vs interstitial techniques, historical planning systems, and specific dose points like ICRU 38's Points A and B.]]></itunes:summary><itunes:duration>3290</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E15a: Brachytherapy Physics - Sources, Strength &amp; Dose Calculation</title><link>https://www.spreaker.com/episode/radphysics-e15a-brachytherapy-physics-sources-strength-dose-calculation--66433168</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've thoroughly covered external beam therapy. Now, we're shifting gears dramatically to explore treatments where the radiation source is placed inside or very close to the target. In Episode P15a: Brachytherapy Physics - Sources, Strength &amp; Dose Calculation, we'll introduce the common radioactive isotopes used, discuss how their strength is properly quantified, and meticulously break down the fundamental TG-43 formalism used for calculating dose around these sources.]]></description><guid isPermaLink="false">eccf4265-50e2-4776-a77d-637885df0613</guid><pubDate>Sat, 07 Jun 2025 04:32:48 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66433168/401732737_44100_2_a740afc263592.mp3" length="57998667" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/400H5SBMCR9bQchbUZ38ym/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! We've thoroughly covered external beam therapy. Now, we're shifting gears dramatically to explore treatments where the radiation source is placed inside or very close to the target. In Episode...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've thoroughly covered external beam therapy. Now, we're shifting gears dramatically to explore treatments where the radiation source is placed inside or very close to the target. In Episode P15a: Brachytherapy Physics - Sources, Strength &amp; Dose Calculation, we'll introduce the common radioactive isotopes used, discuss how their strength is properly quantified, and meticulously break down the fundamental TG-43 formalism used for calculating dose around these sources.]]></itunes:summary><itunes:duration>3625</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E14b: Proton Therapy Physics &amp; Planning</title><link>https://www.spreaker.com/episode/radphysics-e14b-proton-therapy-physics-planning--66424938</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In 14a, we explored the world of electron beams. Now, in Episode 14b: Proton Therapy Physics &amp; Planning, we turn to the heavyweights: protons. Protons offer a unique dose deposition pattern, the Bragg peak, which allows for potentially superior sparing of normal tissues distal to the target. We'll delve into the physics behind proton interactions, how clinical beams are created, the critical challenge of range uncertainty, and specific planning considerations.]]></description><guid isPermaLink="false">7e89fb52-3d42-4edb-8d74-2c583d0616f9</guid><pubDate>Fri, 06 Jun 2025 19:05:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66424938/401713273_44100_2_ed1152f2110b.mp3" length="46769775" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In 14a, we explored the world of electron beams. Now, in Episode 14b: Proton Therapy Physics &amp;amp; Planning, we turn to the heavyweights: protons. Protons offer a unique dose deposition pattern,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In 14a, we explored the world of electron beams. Now, in Episode 14b: Proton Therapy Physics &amp; Planning, we turn to the heavyweights: protons. Protons offer a unique dose deposition pattern, the Bragg peak, which allows for potentially superior sparing of normal tissues distal to the target. We'll delve into the physics behind proton interactions, how clinical beams are created, the critical challenge of range uncertainty, and specific planning considerations.]]></itunes:summary><itunes:duration>2924</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>14</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E14a: Electron Beam Physics &amp; Planning</title><link>https://www.spreaker.com/episode/radphysics-e14a-electron-beam-physics-planning--66424937</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! After exploring advanced photon techniques like IMRT, VMAT, and SRS/SBRT, we're now switching particle types. In Episode P14a: Electron Beam Physics &amp; Planning, we focus entirely on the clinical workhorse for treating shallow targets: the electron beam. We'll examine its unique depth dose characteristics, how its shape changes with depth, planning considerations, and clinical uses.]]></description><guid isPermaLink="false">43970f6a-6e86-4f2a-abaf-155f300fdd0e</guid><pubDate>Fri, 06 Jun 2025 18:37:16 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66424937/401711976_44100_2_6c029e2b30156.mp3" length="53512711" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6NUK363wQBoDEU11hL8YDF/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! After exploring advanced photon techniques like IMRT, VMAT, and SRS/SBRT, we're now switching particle types. In Episode P14a: Electron Beam Physics &amp;amp; Planning, we focus entirely on the...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! After exploring advanced photon techniques like IMRT, VMAT, and SRS/SBRT, we're now switching particle types. In Episode P14a: Electron Beam Physics &amp; Planning, we focus entirely on the clinical workhorse for treating shallow targets: the electron beam. We'll examine its unique depth dose characteristics, how its shape changes with depth, planning considerations, and clinical uses.]]></itunes:summary><itunes:duration>3345</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>14</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E13b: Stereotactic Techniques (SRS &amp; SBRT Physics &amp; Delivery)</title><link>https://www.spreaker.com/episode/radphysics-e13b-stereotactic-techniques-srs-sbrt-physics-delivery--66424944</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P13a, we covered the principles of IMRT and VMAT for delivering conformal dose distributions. Today, in Episode P13b: Stereotactic Techniques, we push the boundaries of precision even further. We'll explore Stereotactic Radiosurgery (SRS) for the brain and Stereotactic Body Radiation Therapy (SBRT), also known as SABR, for targets outside the brain. These techniques deliver highly focused, often ablative doses with extreme accuracy, demanding specialized equipment and meticulous physics support.]]></description><guid isPermaLink="false">1582a35e-d193-4f5d-9aff-f25070d28e44</guid><pubDate>Fri, 06 Jun 2025 18:27:16 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66424944/401711448_44100_2_bbb5cc0fcf60c.mp3" length="60011558" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0u4Gig7XDFmJClFrXAi3CK/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P13a, we covered the principles of IMRT and VMAT for delivering conformal dose distributions. Today, in Episode P13b: Stereotactic Techniques, we push the boundaries of precision even further....</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P13a, we covered the principles of IMRT and VMAT for delivering conformal dose distributions. Today, in Episode P13b: Stereotactic Techniques, we push the boundaries of precision even further. We'll explore Stereotactic Radiosurgery (SRS) for the brain and Stereotactic Body Radiation Therapy (SBRT), also known as SABR, for targets outside the brain. These techniques deliver highly focused, often ablative doses with extreme accuracy, demanding specialized equipment and meticulous physics support.]]></itunes:summary><itunes:duration>3751</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E13a: Intensity Modulated Therapy (IMRT &amp; VMAT Principles, QA)</title><link>https://www.spreaker.com/episode/radphysics-e13a-intensity-modulated-therapy-imrt-vmat-principles-qa--66414285</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P12b, we defined the crucial ICRU target volumes (GTV, CTV, PTV). Now, how do we deliver dose that conforms tightly to those volumes, especially when they're complex shapes wrapped around sensitive organs? In Episode P13a: Intensity Modulated Therapy (IMRT &amp; VMAT Principles, QA), we explore the sophisticated techniques of IMRT and VMAT that allow us to "dose paint" with remarkable precision, and the essential QA needed to ensure they work as planned.]]></description><guid isPermaLink="false">d4ad61c2-cab1-49c1-810b-f456a9682c76</guid><pubDate>Fri, 06 Jun 2025 00:01:12 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66414285/401666885_44100_2_d7b0d682cfb18.mp3" length="32211839" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7AoGM2qQSHisO5RNNoHZrq/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P12b, we defined the crucial ICRU target volumes (GTV, CTV, PTV). Now, how do we deliver dose that conforms tightly to those volumes, especially when they're complex shapes wrapped around...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P12b, we defined the crucial ICRU target volumes (GTV, CTV, PTV). Now, how do we deliver dose that conforms tightly to those volumes, especially when they're complex shapes wrapped around sensitive organs? In Episode P13a: Intensity Modulated Therapy (IMRT &amp; VMAT Principles, QA), we explore the sophisticated techniques of IMRT and VMAT that allow us to "dose paint" with remarkable precision, and the essential QA needed to ensure they work as planned.]]></itunes:summary><itunes:duration>2014</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E12b: Treatment Planning Volumes &amp; Concepts</title><link>https://www.spreaker.com/episode/radphysics-e12b-treatment-planning-volumes-concepts--66412863</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In E12a, we mastered the formulas for calculating Monitor Units to deliver a specific dose to a point. But radiation therapy treats volumes. How do we define these volumes precisely, accounting for not just the visible tumor but also microscopic spread and uncertainties in setup and motion? In Episode 12b: Treatment Planning Volumes &amp; Concepts, we introduce the standardized language defined by the ICRU (International Commission on Radiation Units and Measurements) for describing target volumes and organs at risk, laying the foundation for evaluating treatment plans.]]></description><guid isPermaLink="false">2c8d2198-2e41-4b07-881c-644a51ae2620</guid><pubDate>Thu, 05 Jun 2025 20:24:20 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66412863/401655258_44100_2_111bd02f64b9c.mp3" length="44448430" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6ccN3nXWXihdhn3tdmUoNl/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In E12a, we mastered the formulas for calculating Monitor Units to deliver a specific dose to a point. But radiation therapy treats volumes. How do we define these volumes precisely, accounting...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In E12a, we mastered the formulas for calculating Monitor Units to deliver a specific dose to a point. But radiation therapy treats volumes. How do we define these volumes precisely, accounting for not just the visible tumor but also microscopic spread and uncertainties in setup and motion? In Episode 12b: Treatment Planning Volumes &amp; Concepts, we introduce the standardized language defined by the ICRU (International Commission on Radiation Units and Measurements) for describing target volumes and organs at risk, laying the foundation for evaluating treatment plans.]]></itunes:summary><itunes:duration>2778</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>12</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E12a: MU Calculations (SSD &amp; SAD Formulas)</title><link>https://www.spreaker.com/episode/radphysics-e12a-mu-calculations-ssd-sad-formulas--66387342</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've gathered all the ingredients: Calibrated Output (CAL), Output Factors (Sc,p), Beam Modifiers (WF, TF), and Patient Attenuation Factors (PDD, TMR). Now, in Episode P12a: MU Calculations (SSD &amp; SAD Formulas), we finally put them together! We'll construct and explain the complete formulas used to calculate Monitor Units (MUs) for both common treatment techniques: fixed Source-to-Surface Distance (SSD) and isocentric Source-to-Axis Distance (SAD).]]></description><guid isPermaLink="false">ff0cf79c-3bfa-4b5d-baf5-1c87679891d6</guid><pubDate>Tue, 03 Jun 2025 21:03:56 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66387342/401523797_44100_2_783a9839b110f.mp3" length="45314441" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2wqmc0Zk6zHyGWFiIZjvAQ/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! We've gathered all the ingredients: Calibrated Output (CAL), Output Factors (Sc,p), Beam Modifiers (WF, TF), and Patient Attenuation Factors (PDD, TMR). Now, in Episode P12a: MU Calculations (SSD...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've gathered all the ingredients: Calibrated Output (CAL), Output Factors (Sc,p), Beam Modifiers (WF, TF), and Patient Attenuation Factors (PDD, TMR). Now, in Episode P12a: MU Calculations (SSD &amp; SAD Formulas), we finally put them together! We'll construct and explain the complete formulas used to calculate Monitor Units (MUs) for both common treatment techniques: fixed Source-to-Surface Distance (SSD) and isocentric Source-to-Axis Distance (SAD).]]></itunes:summary><itunes:duration>2833</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>12</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E11: MU Calculation Components</title><link>https://www.spreaker.com/episode/radphysics-e11-mu-calculation-components--66387341</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In Episode P10, we defined the key descriptors of dose distribution – PDD for SSD setups and TMR for SAD setups – which tell us how dose varies with depth, energy, and field size relative to a reference point (dmax). Now, in Episode P11: MU Calculation Components, we'll assemble the rest of the puzzle pieces needed to actually calculate the Monitor Units (MUs) required to deliver the prescribed dose. We'll focus on output factors (Sc, Sp), equivalent squares, and factors for beam modifiers like wedges and trays.]]></description><guid isPermaLink="false">2dc74e8d-18d8-4a74-bf97-5aa1aaee9453</guid><pubDate>Tue, 03 Jun 2025 20:24:12 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66387341/401521551_44100_2_dc4807b5f319c.mp3" length="33540113" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/1EpDgZH06wmeIdsx3sqzOK/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In Episode P10, we defined the key descriptors of dose distribution – PDD for SSD setups and TMR for SAD setups – which tell us how dose varies with depth, energy, and field size relative to a...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In Episode P10, we defined the key descriptors of dose distribution – PDD for SSD setups and TMR for SAD setups – which tell us how dose varies with depth, energy, and field size relative to a reference point (dmax). Now, in Episode P11: MU Calculation Components, we'll assemble the rest of the puzzle pieces needed to actually calculate the Monitor Units (MUs) required to deliver the prescribed dose. We'll focus on output factors (Sc, Sp), equivalent squares, and factors for beam modifiers like wedges and trays.]]></itunes:summary><itunes:duration>2097</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>11</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E10: EBRT Dose Descriptors</title><link>https://www.spreaker.com/episode/radphysics-e10-ebrt-dose-descriptors--66386677</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P9, we mastered the art of calibration using TG-51, linking machine output (MU) to absolute dose under reference conditions. But patients aren't water phantoms treated at 10 cm depth with a 10x10 field! So, how does dose actually distribute within a patient? In Episode P10: External Beam Dose Descriptors (Part 1), we begin our dive into Chapter 12, focusing on key concepts like electron buildup, dmax, Percent Depth Dose (PDD), and the family of Tissue-Air/Phantom/Maximum Ratios (TAR, TPR, TMR) used to characterize dose distribution.]]></description><guid isPermaLink="false">9bd27c1d-cef9-4a9a-b4ed-c396b6319dbc</guid><pubDate>Tue, 03 Jun 2025 19:32:23 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66386677/401518462_44100_2_531f972e3eeac.mp3" length="35848920" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2PuzGH8aTigqeUuPTk6eX8/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P9, we mastered the art of calibration using TG-51, linking machine output (MU) to absolute dose under reference conditions. But patients aren't water phantoms treated at 10 cm depth with a...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P9, we mastered the art of calibration using TG-51, linking machine output (MU) to absolute dose under reference conditions. But patients aren't water phantoms treated at 10 cm depth with a 10x10 field! So, how does dose actually distribute within a patient? In Episode P10: External Beam Dose Descriptors (Part 1), we begin our dive into Chapter 12, focusing on key concepts like electron buildup, dmax, Percent Depth Dose (PDD), and the family of Tissue-Air/Phantom/Maximum Ratios (TAR, TPR, TMR) used to characterize dose distribution.]]></itunes:summary><itunes:duration>2241</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>10</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E9: TG-51 Calibration Essentials</title><link>https://www.spreaker.com/episode/radphysics-e9-tg-51-calibration-essentials--66377595</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P8, we stressed the importance of Quality Assurance – making sure our LINACs work correctly. But QA relies on having an accurate baseline measurement of the machine's output. How do we establish that baseline? That's where Calibration comes in. Today, in Episode P9: Calibration Essentials, we'll demystify the process of calibrating a LINAC, focusing on the current standard protocol in the US: the AAPM's Task Group 51 report, or TG-51.]]></description><guid isPermaLink="false">f2accd5e-8f07-4716-9215-a12eeeaa50bb</guid><pubDate>Tue, 03 Jun 2025 02:26:48 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66377595/401472221_44100_2_632e8435bccc3.mp3" length="45274735" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4zbxVHtiXBjr80ArhZemuV/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P8, we stressed the importance of Quality Assurance – making sure our LINACs work correctly. But QA relies on having an accurate baseline measurement of the machine's output. How do we...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P8, we stressed the importance of Quality Assurance – making sure our LINACs work correctly. But QA relies on having an accurate baseline measurement of the machine's output. How do we establish that baseline? That's where Calibration comes in. Today, in Episode P9: Calibration Essentials, we'll demystify the process of calibrating a LINAC, focusing on the current standard protocol in the US: the AAPM's Task Group 51 report, or TG-51.]]></itunes:summary><itunes:duration>2830</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>9</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E08:Beam Quality &amp; Characteristics</title><link>https://www.spreaker.com/episode/radphysics-e08-beam-quality-characteristics--66375981</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! After diving deep into dosimetry detectors and concepts in P7a and P7b, we now turn our focus in Episode P8a to the Beam Quality &amp; Characteristics. How do we objectively describe the penetrating power of our radiation beams? What factors influence this quality? We'll explore concepts like Half-Value Layer (HVL), beam hardening, and how quality is specified for both kilovoltage and megavoltage beams.]]></description><guid isPermaLink="false">3cfe3024-d7af-4ed4-88ff-a4977b4df7ce</guid><pubDate>Mon, 02 Jun 2025 22:40:13 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66375981/401463352_44100_2_a2921db8629b2.mp3" length="43308655" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0uNsTm2OwajgWZ0bcnHSB3/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! After diving deep into dosimetry detectors and concepts in P7a and P7b, we now turn our focus in Episode P8a to the Beam Quality &amp;amp; Characteristics. How do we objectively describe the...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! After diving deep into dosimetry detectors and concepts in P7a and P7b, we now turn our focus in Episode P8a to the Beam Quality &amp; Characteristics. How do we objectively describe the penetrating power of our radiation beams? What factors influence this quality? We'll explore concepts like Half-Value Layer (HVL), beam hardening, and how quality is specified for both kilovoltage and megavoltage beams.]]></itunes:summary><itunes:duration>2707</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>8</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E07b: Bragg-Gray Theory &amp; The Dosimetry Toolkit</title><link>https://www.spreaker.com/episode/radphysics-e07b-bragg-gray-theory-the-dosimetry-toolkit--66374074</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P7a, we established the concept of Exposure, detailed the ionization chamber, and learned how the f-factor converts exposure-in-air to dose-in-medium. But how can we be sure that measuring ionization in that tiny air cavity inside our water phantom accurately tells us the dose in the water? That's the focus of the first part of Episode P7b: Bragg-Gray Theory &amp; The Dosimetry Toolkit. We'll unravel this fundamental theory and then survey the rest of the physicist's toolkit – the various detectors beyond the ion chamber used for different measurement tasks.]]></description><guid isPermaLink="false">b85d1170-b1ee-4452-8664-ae27309b0f8c</guid><pubDate>Mon, 02 Jun 2025 19:32:27 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66374074/401452348_44100_2_88f79ed3a4dec.mp3" length="38071209" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/7dhB0X5GPgChdJkMmzgJ1K/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P7a, we established the concept of Exposure, detailed the ionization chamber, and learned how the f-factor converts exposure-in-air to dose-in-medium. But how can we be sure that measuring...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P7a, we established the concept of Exposure, detailed the ionization chamber, and learned how the f-factor converts exposure-in-air to dose-in-medium. But how can we be sure that measuring ionization in that tiny air cavity inside our water phantom accurately tells us the dose in the water? That's the focus of the first part of Episode P7b: Bragg-Gray Theory &amp; The Dosimetry Toolkit. We'll unravel this fundamental theory and then survey the rest of the physicist's toolkit – the various detectors beyond the ion chamber used for different measurement tasks.]]></itunes:summary><itunes:duration>2380</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>7</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E06: Photon Interactions &amp; Basic Dose Concepts</title><link>https://www.spreaker.com/episode/radphysics-e06-photon-interactions-basic-dose-concepts--66362959</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P5, we explored the powerful machines, especially LINACs, that generate high-energy photon (X-ray) beams. Now that we have these beams, what happens when they actually hit the patient? In Episode P6: Photon Interactions &amp; Basic Dose Concepts, we'll uncover how these energetic photons interact with matter, transfer their energy, and lead to the concepts of Kerma and Absorbed Dose.]]></description><guid isPermaLink="false">55523ba9-bb80-40d1-a1e6-ec3de1720ed5</guid><pubDate>Mon, 02 Jun 2025 04:17:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66362959/401408846_44100_2_1695278545d46.mp3" length="24624626" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/5tILS52FP2D6SjiaCk0twL/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P5, we explored the powerful machines, especially LINACs, that generate high-energy photon (X-ray) beams. Now that we have these beams, what happens when they actually hit the patient? In...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P5, we explored the powerful machines, especially LINACs, that generate high-energy photon (X-ray) beams. Now that we have these beams, what happens when they actually hit the patient? In Episode P6: Photon Interactions &amp; Basic Dose Concepts, we'll uncover how these energetic photons interact with matter, transfer their energy, and lead to the concepts of Kerma and Absorbed Dose.]]></itunes:summary><itunes:duration>1539</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>6</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E05: High Energy Treatment Machines</title><link>https://www.spreaker.com/episode/radphysics-e05-high-energy-treatment-machines--66362960</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! Last episode, P4, we learned how kV X-rays are produced in tubes. Today, we're powering up significantly in Episode P5: High Energy Treatment Machines. We'll explore the historical Cobalt-60 units and then spend most of our time dissecting the modern workhorse of radiation oncology: the Linear Accelerator, or LINAC. We'll journey through its complex components, from generating electrons to shaping the final treatment beam.]]></description><guid isPermaLink="false">7463d845-4693-48e7-a7a7-ca1b89c2938a</guid><pubDate>Mon, 02 Jun 2025 04:14:51 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66362960/401408814_44100_2_b77d71ef4169d.mp3" length="21928789" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3JvYnTO4nouOD1akFcmwMZ/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! Last episode, P4, we learned how kV X-rays are produced in tubes. Today, we're powering up significantly in Episode P5: High Energy Treatment Machines. We'll explore the historical Cobalt-60...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! Last episode, P4, we learned how kV X-rays are produced in tubes. Today, we're powering up significantly in Episode P5: High Energy Treatment Machines. We'll explore the historical Cobalt-60 units and then spend most of our time dissecting the modern workhorse of radiation oncology: the Linear Accelerator, or LINAC. We'll journey through its complex components, from generating electrons to shaping the final treatment beam.]]></itunes:summary><itunes:duration>1371</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>5</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics E04: kV X-ray Production</title><link>https://www.spreaker.com/episode/physics-e04-kv-x-ray-production--66353561</link><description><![CDATA[Welcome back to RadOnc Smart Review, Physics Series! In P3, we saw how charged particles like electrons lose energy interacting with matter. Today, in Episode P4: kV X-ray Production, we harness those interactions! We'll focus specifically on how we generate kilovoltage (kV) X-rays, the kind used ubiquitously in diagnostic imaging (like CT and cone-beam CT) and historically in orthovoltage therapy. We'll dissect the X-ray tube and the physics behind creating those useful photons.]]></description><guid isPermaLink="false">ca42cb9d-149a-4aee-aefc-da4f188c5f0f</guid><pubDate>Sun, 01 Jun 2025 01:21:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66353561/401352089_44100_2_7bd496c894cb7.mp3" length="32008293" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to RadOnc Smart Review, Physics Series! In P3, we saw how charged particles like electrons lose energy interacting with matter. Today, in Episode P4: kV X-ray Production, we harness those interactions! We'll focus specifically on how we...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to RadOnc Smart Review, Physics Series! In P3, we saw how charged particles like electrons lose energy interacting with matter. Today, in Episode P4: kV X-ray Production, we harness those interactions! We'll focus specifically on how we generate kilovoltage (kV) X-rays, the kind used ubiquitously in diagnostic imaging (like CT and cone-beam CT) and historically in orthovoltage therapy. We'll dissect the X-ray tube and the physics behind creating those useful photons.]]></itunes:summary><itunes:duration>2001</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>4</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E07a: Measuring Dose - Exposure, Ion Chambers &amp; The f-factor</title><link>https://www.spreaker.com/episode/radphysics-e07a-measuring-dose-exposure-ion-chambers-the-f-factor--66353187</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P6, we saw how photons interact – PE, Compton, Pair Production. Now we need to quantify the result: dose. In Episode P7a: Measuring Dose - Exposure, Ion Chambers &amp; The f-factor, we'll start this journey. We'll cover the historical concept of Exposure, dive deep into the workhorse detector – the Ionization Chamber, and introduce the crucial 'f-factor' that bridges the gap between measuring ionization in air and understanding dose in tissue.]]></description><guid isPermaLink="false">8c88e4c2-9d4a-4455-9c4b-012ded9f0c88</guid><pubDate>Sat, 31 May 2025 22:31:22 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66353187/401347859_44100_2_2b787f09a85aa.mp3" length="37460570" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0vicPlsMhh5lz3BsIEj5oL/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P6, we saw how photons interact – PE, Compton, Pair Production. Now we need to quantify the result: dose. In Episode P7a: Measuring Dose - Exposure, Ion Chambers &amp;amp; The f-factor, we'll...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P6, we saw how photons interact – PE, Compton, Pair Production. Now we need to quantify the result: dose. In Episode P7a: Measuring Dose - Exposure, Ion Chambers &amp; The f-factor, we'll start this journey. We'll cover the historical concept of Exposure, dive deep into the workhorse detector – the Ionization Chamber, and introduce the crucial 'f-factor' that bridges the gap between measuring ionization in air and understanding dose in tissue.]]></itunes:summary><itunes:duration>2342</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>7</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E03: Particulate Interactions</title><link>https://www.spreaker.com/episode/radphysics-e03-particulate-interactions--66346283</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P2, we explored radioactive decay, where unstable nuclei emit particles like alphas and betas. Now, in Episode P3: Particulate Interactions, we'll follow those particles – and others like electrons and protons accelerated in our machines, plus neutrons – as they travel through matter. How do they lose energy? What factors determine how far they go? And what makes protons deposit their dose so differently?]]></description><guid isPermaLink="false">7eef0911-3e3e-458c-b87b-c47bba5e8379</guid><pubDate>Fri, 30 May 2025 23:59:24 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66346283/401310343_44100_2_40259bdd15e34.mp3" length="21586063" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/6z64ArZuvnBfkKHKSjhNC7/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P2, we explored radioactive decay, where unstable nuclei emit particles like alphas and betas. Now, in Episode P3: Particulate Interactions, we'll follow those particles – and others like...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P2, we explored radioactive decay, where unstable nuclei emit particles like alphas and betas. Now, in Episode P3: Particulate Interactions, we'll follow those particles – and others like electrons and protons accelerated in our machines, plus neutrons – as they travel through matter. How do they lose energy? What factors determine how far they go? And what makes protons deposit their dose so differently?]]></itunes:summary><itunes:duration>1350</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>3</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E02: Radioactive Decay</title><link>https://www.spreaker.com/episode/radphysics-e02-radioactive-decay--66346282</link><description><![CDATA[Welcome back to RadOnc Smart Review, Physics Series! Last time, in P1, we looked at the atom's structure and what happens when electrons get shuffled around. Today, in Episode 2: Radioactive Decay, we're focusing on the nucleus itself and what happens when it's unstable. We'll cover the different ways nuclei decay, how we measure that decay, and what happens when radioactive parents produce radioactive daughters.]]></description><guid isPermaLink="false">db415e0b-5de9-4da9-b884-f377f3ce56b3</guid><pubDate>Fri, 30 May 2025 23:53:53 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66346282/401310156_44100_2_ec2ffe869e1ba.mp3" length="27763917" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/2NQyyjhayeX4QvDw4ebga2/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to RadOnc Smart Review, Physics Series! Last time, in P1, we looked at the atom's structure and what happens when electrons get shuffled around. Today, in Episode 2: Radioactive Decay, we're focusing on the nucleus itself and what happens...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to RadOnc Smart Review, Physics Series! Last time, in P1, we looked at the atom's structure and what happens when electrons get shuffled around. Today, in Episode 2: Radioactive Decay, we're focusing on the nucleus itself and what happens when it's unstable. We'll cover the different ways nuclei decay, how we measure that decay, and what happens when radioactive parents produce radioactive daughters.]]></itunes:summary><itunes:duration>1736</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>2</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadPhysics E1: Atomic and Nuclear Structure</title><link>https://www.spreaker.com/episode/radphysics-e1-atomic-and-nuclear-structure--66346284</link><description><![CDATA[Welcome to RadOnc Smart Review, the podcast dedicated to sharpening your radiation oncology expertise. This is the very first episode of our Physics Series, E1: Atomic and Nuclear Structure. Today, we're going back to the absolute basics, the tiny building blocks that underpin everything we do in radiation therapy. We'll cover the fundamental particles, electron shells, binding energy, and what happens when things get knocked out of place. Ready to build our foundation?]]></description><guid isPermaLink="false">0aca962d-7d09-4df6-b48b-530ed05132b1</guid><pubDate>Fri, 30 May 2025 23:44:28 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66346284/401309878_44100_2_a0ed20e303c8d.mp3" length="16804610" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/0zyv0zA1YPrtItuEebYfoG/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome to RadOnc Smart Review, the podcast dedicated to sharpening your radiation oncology expertise. This is the very first episode of our Physics Series, E1: Atomic and Nuclear Structure. Today, we're going back to the absolute basics, the tiny...</itunes:subtitle><itunes:summary><![CDATA[Welcome to RadOnc Smart Review, the podcast dedicated to sharpening your radiation oncology expertise. This is the very first episode of our Physics Series, E1: Atomic and Nuclear Structure. Today, we're going back to the absolute basics, the tiny building blocks that underpin everything we do in radiation therapy. We'll cover the fundamental particles, electron shells, binding energy, and what happens when things get knocked out of place. Ready to build our foundation?]]></itunes:summary><itunes:duration>1051</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>1</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E38: Oncogenic Pathways: RAS/MAPK, PI3K/AKT/mTOR, and HIF-1α</title><link>https://www.spreaker.com/episode/radbio-e38-oncogenic-pathways-ras-mapk-pi3k-akt-mtor-and-hif-1a--66345082</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 38: Oncogenic Pathways: RAS/MAPK, PI3K/AKT/mTOR, and HIF-1α. In our previous discussions, we've explored how cells sense and repair DNA damage, and how they make life-or-death decisions through apoptosis. Today, we're shifting our focus to some of the major signaling pathways that, when dysregulated, drive cancer development and can profoundly influence a tumor's response to radiation therapy. We'll dissect the RAS/RAF/MEK/ERK pathway, a critical engine for cell proliferation; the PI3K/AKT/mTOR pathway, a master regulator of cell growth, survival, and metabolism; and the HIF-1α pathway, which allows cells to adapt to hypoxic conditions. We'll also discuss how these pathways are commonly altered in cancer and contribute to radioresistance, and touch upon strategies to target them therapeutically.]]></description><guid isPermaLink="false">d688a2a8-6778-4add-ba52-babc16d47054</guid><pubDate>Fri, 30 May 2025 20:37:43 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66345082/401302643_44100_2_46059577ddd2a.mp3" length="27212211" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3Nlg7clRn6r72PVb574hoy/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is Episode 38: Oncogenic Pathways: RAS/MAPK, PI3K/AKT/mTOR, and HIF-1α. In our previous discussions, we've explored how cells sense and repair DNA damage, and how they make life-or-death decisions through...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 38: Oncogenic Pathways: RAS/MAPK, PI3K/AKT/mTOR, and HIF-1α. In our previous discussions, we've explored how cells sense and repair DNA damage, and how they make life-or-death decisions through apoptosis. Today, we're shifting our focus to some of the major signaling pathways that, when dysregulated, drive cancer development and can profoundly influence a tumor's response to radiation therapy. We'll dissect the RAS/RAF/MEK/ERK pathway, a critical engine for cell proliferation; the PI3K/AKT/mTOR pathway, a master regulator of cell growth, survival, and metabolism; and the HIF-1α pathway, which allows cells to adapt to hypoxic conditions. We'll also discuss how these pathways are commonly altered in cancer and contribute to radioresistance, and touch upon strategies to target them therapeutically.]]></itunes:summary><itunes:duration>1701</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>38</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E37: G2/M Control (Wee1) &amp; Apoptosis (Bcl-2/Caspases)</title><link>https://www.spreaker.com/episode/radbio-e37-g2-m-control-wee1-apoptosis-bcl-2-caspases--66345084</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 37: G2/M Control (Wee1) &amp; Apoptosis (Bcl-2/Caspases). In our previous episode, we explored the intricate mechanisms of G1/S checkpoint control, highlighting the roles of p53, p21, and the Rb/E2F pathway. Today, we shift our focus to another critical regulatory point, the G2/M transition, and then delve into the fascinating and highly regulated process of programmed cell death, or apoptosis. We'll examine how Wee1 kinase and Cdc25 phosphatases govern entry into mitosis, and then explore both the intrinsic (mitochondrial) and extrinsic (death receptor) pathways of apoptosis, paying close attention to the Bcl-2 family of proteins and the caspase cascade. Understanding these pathways is fundamental to grasping how cells respond to damage and how cancer cells often evade these critical controls.]]></description><guid isPermaLink="false">584fb116-8e48-4a3d-8e5e-8e3a97c89ec4</guid><pubDate>Fri, 30 May 2025 20:24:15 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66345084/401302047_44100_2_173c95017f35e.mp3" length="28867330" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3qi24Xyr8NHJs54j315rd5/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is Episode 37: G2/M Control (Wee1) &amp;amp; Apoptosis (Bcl-2/Caspases). In our previous episode, we explored the intricate mechanisms of G1/S checkpoint control, highlighting the roles of p53, p21, and the...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 37: G2/M Control (Wee1) &amp; Apoptosis (Bcl-2/Caspases). In our previous episode, we explored the intricate mechanisms of G1/S checkpoint control, highlighting the roles of p53, p21, and the Rb/E2F pathway. Today, we shift our focus to another critical regulatory point, the G2/M transition, and then delve into the fascinating and highly regulated process of programmed cell death, or apoptosis. We'll examine how Wee1 kinase and Cdc25 phosphatases govern entry into mitosis, and then explore both the intrinsic (mitochondrial) and extrinsic (death receptor) pathways of apoptosis, paying close attention to the Bcl-2 family of proteins and the caspase cascade. Understanding these pathways is fundamental to grasping how cells respond to damage and how cancer cells often evade these critical controls.]]></itunes:summary><itunes:duration>1805</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>37</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E36: Cell Cycle Gate keepers: p53/p21 &amp; Rb/E2F</title><link>https://www.spreaker.com/episode/radbio-e36-cell-cycle-gate-keepers-p53-p21-rb-e2f--66344670</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 36: Cell Cycle Gatekeepers: p53/p21 &amp; Rb/E2F. In our previous episodes, we've delved into how cells sense and repair DNA damage. Today, we're going to focus on two critical molecular pathways that act as gatekeepers of the cell cycle, ensuring that cells don't progress with damaged DNA, which could lead to mutations and cancer. We'll explore how the tumor suppressor p53 is activated by DNA damage, its regulation by MDM2, and how p53 then induces p21 to halt the cell cycle in G1. We'll also dissect the Rb/E2F pathway, another crucial checkpoint controlling the G1 to S phase transition, and how it's regulated by cyclin-dependent kinases.]]></description><guid isPermaLink="false">d752615c-a253-4e08-8575-365bc641784d</guid><pubDate>Fri, 30 May 2025 19:39:13 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66344670/401299197_44100_2_791520d7fc9bc.mp3" length="19462830" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/3G8gEY4q9E9w5aKYv5MHq2/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is Episode 36: Cell Cycle Gatekeepers: p53/p21 &amp;amp; Rb/E2F. In our previous episodes, we've delved into how cells sense and repair DNA damage. Today, we're going to focus on two critical molecular pathways...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 36: Cell Cycle Gatekeepers: p53/p21 &amp; Rb/E2F. In our previous episodes, we've delved into how cells sense and repair DNA damage. Today, we're going to focus on two critical molecular pathways that act as gatekeepers of the cell cycle, ensuring that cells don't progress with damaged DNA, which could lead to mutations and cancer. We'll explore how the tumor suppressor p53 is activated by DNA damage, its regulation by MDM2, and how p53 then induces p21 to halt the cell cycle in G1. We'll also dissect the Rb/E2F pathway, another crucial checkpoint controlling the G1 to S phase transition, and how it's regulated by cyclin-dependent kinases.]]></itunes:summary><itunes:duration>1217</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>36</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E35: DSB Repair Deep Dive: NHEJ &amp; HRR Proteins</title><link>https://www.spreaker.com/episode/radbio-e35-dsb-repair-deep-dive-nhej-hrr-proteins--66337631</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 35: DSB Repair Deep Dive: NHEJ &amp; HRR Proteins. In our last episode, we explored how cells sense DNA damage and initiate signaling cascades. Today, we're diving into the critical repair mechanisms themselves, focusing on how cells mend the most dangerous of DNA lesions – double-strand breaks (DSBs). We'll compare and contrast the two major DSB repair pathways: Non-Homologous End Joining (NHEJ) and Homologous Recombination Repair (HRR), looking at their fidelity, template requirements, and cell cycle specificity. We'll then dissect the key protein players and the step-by-step processes involved in each pathway, and finally, discuss the clinical significance of defects in these pathways, particularly mutations in BRCA1 and BRCA2.]]></description><guid isPermaLink="false">3bf43d5f-db77-4a59-8f2e-b216706ec451</guid><pubDate>Fri, 30 May 2025 07:30:16 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66337631/401268255_44100_2_e1b3ea550fdea.mp3" length="28851029" type="audio/mpeg"/><podcast:transcript url="https://transcript-files.spotifycdn.com/6iqtKB9HLHCmcjc0ZBLo7V/4OT9axvRjzJppXrTdNiQPZ/transcript.srt" type="application/x-subrip" language="en"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is Episode 35: DSB Repair Deep Dive: NHEJ &amp;amp; HRR Proteins. In our last episode, we explored how cells sense DNA damage and initiate signaling cascades. Today, we're diving into the critical repair...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 35: DSB Repair Deep Dive: NHEJ &amp; HRR Proteins. In our last episode, we explored how cells sense DNA damage and initiate signaling cascades. Today, we're diving into the critical repair mechanisms themselves, focusing on how cells mend the most dangerous of DNA lesions – double-strand breaks (DSBs). We'll compare and contrast the two major DSB repair pathways: Non-Homologous End Joining (NHEJ) and Homologous Recombination Repair (HRR), looking at their fidelity, template requirements, and cell cycle specificity. We'll then dissect the key protein players and the step-by-step processes involved in each pathway, and finally, discuss the clinical significance of defects in these pathways, particularly mutations in BRCA1 and BRCA2.]]></itunes:summary><itunes:duration>1804</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>35</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E34: DNA Damage Sensing &amp; Signaling: ATM, ATR, and γH2AX</title><link>https://www.spreaker.com/episode/radbio-e34-dna-damage-sensing-signaling-atm-atr-and-gh2ax--66334333</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 34: DNA Damage Sensing &amp; Signaling: ATM, ATR, and γH2AX. Today, we're diving deep into the cell's intricate emergency response system, the DNA Damage Response, or DDR. We'll explore how cells detect various types of DNA damage, particularly the highly cytotoxic double-strand breaks (DSBs) and replication stress, and how a sophisticated network of sensor, transducer, and effector proteins orchestrates cell cycle checkpoints, DNA repair, and sometimes, apoptosis. We'll meticulously unpack the roles of master kinases ATM and ATR, the initial damage sensing by the MRN complex, the crucial modification of H2AX to γH2AX, and the activation of downstream checkpoint kinases CHK1 and CHK2, all vital for maintaining genomic integrity and highly relevant for your board exams.]]></description><guid isPermaLink="false">5da3cc05-b9f1-46e0-8d8d-41846e43b84c</guid><pubDate>Thu, 29 May 2025 22:25:29 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66334333/401248091_44100_2_248a42f5b7447.mp3" length="28207790" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is Episode 34: DNA Damage Sensing &amp;amp; Signaling: ATM, ATR, and γH2AX. Today, we're diving deep into the cell's intricate emergency response system, the DNA Damage Response, or DDR. We'll explore how cells...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is Episode 34: DNA Damage Sensing &amp; Signaling: ATM, ATR, and γH2AX. Today, we're diving deep into the cell's intricate emergency response system, the DNA Damage Response, or DDR. We'll explore how cells detect various types of DNA damage, particularly the highly cytotoxic double-strand breaks (DSBs) and replication stress, and how a sophisticated network of sensor, transducer, and effector proteins orchestrates cell cycle checkpoints, DNA repair, and sometimes, apoptosis. We'll meticulously unpack the roles of master kinases ATM and ATR, the initial damage sensing by the MRN complex, the crucial modification of H2AX to γH2AX, and the activation of downstream checkpoint kinases CHK1 and CHK2, all vital for maintaining genomic integrity and highly relevant for your board exams.]]></itunes:summary><itunes:duration>1763</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>36</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E32: Molecular Imaging (CT &amp; PET)</title><link>https://www.spreaker.com/episode/radbio-e32-molecular-imaging-ct-pet--66333926</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is RadBio Edition, Episode 32: Molecular Imaging (CT &amp; PET) in RadOnc.In our previous episode, we explored the molecular tools that help us understand DNA damage, gene expression, and protein function. Today, we're moving from the lab bench into the clinic to see how some of these molecular principles are visualized and applied through advanced imaging techniques. We'll focus on Computed Tomography (CT) and Positron Emission Tomography (PET), discussing their physical principles, common contrast agents and radiotracers, and their crucial roles in cancer diagnosis, staging, treatment planning, and response assessment in radiation oncology.]]></description><guid isPermaLink="false">26c57de4-afa9-4861-b2de-59e627a171a2</guid><pubDate>Thu, 29 May 2025 22:22:59 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66333926/401248007_44100_2_cf0deaa99ce3e.mp3" length="22159503" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is RadBio Edition, Episode 32: Molecular Imaging (CT &amp;amp; PET) in RadOnc.In our previous episode, we explored the molecular tools that help us understand DNA damage, gene expression, and protein function....</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is RadBio Edition, Episode 32: Molecular Imaging (CT &amp; PET) in RadOnc.In our previous episode, we explored the molecular tools that help us understand DNA damage, gene expression, and protein function. Today, we're moving from the lab bench into the clinic to see how some of these molecular principles are visualized and applied through advanced imaging techniques. We'll focus on Computed Tomography (CT) and Positron Emission Tomography (PET), discussing their physical principles, common contrast agents and radiotracers, and their crucial roles in cancer diagnosis, staging, treatment planning, and response assessment in radiation oncology.]]></itunes:summary><itunes:duration>1385</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>32</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E33: Cancer Immunology &amp; Radiation Synergy</title><link>https://www.spreaker.com/episode/radbio-e33-cancer-immunology-radiation-synergy--66333935</link><description><![CDATA[Welcome back to Rad Onc Smart Review! Rad Bio Edition! Today we’re exploring a very hot topic in cancer therapy: the intersection of radiation and the immune system. This is Episode 33: Cancer Immunology &amp; Radiation Synergy. For a long time, radiation was thought of primarily as a local, directly cytotoxic treatment. But we now understand that radiation doesn't just kill cancer cells; it can profoundly modulate the immune system and the tumor microenvironment. We'll discuss how radiation can sometimes turn a "cold" tumor "hot," making it more visible to the immune system, and how this understanding is paving the way for powerful combination therapies, especially with immune checkpoint inhibitors.]]></description><guid isPermaLink="false">264ff5fe-da1b-4310-b654-00482ac87e5a</guid><pubDate>Thu, 29 May 2025 21:33:35 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66333935/401245823_44100_2_88ff1d290dfa6.mp3" length="20915656" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! Rad Bio Edition! Today we’re exploring a very hot topic in cancer therapy: the intersection of radiation and the immune system. This is Episode 33: Cancer Immunology &amp;amp; Radiation Synergy. For a long time,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! Rad Bio Edition! Today we’re exploring a very hot topic in cancer therapy: the intersection of radiation and the immune system. This is Episode 33: Cancer Immunology &amp; Radiation Synergy. For a long time, radiation was thought of primarily as a local, directly cytotoxic treatment. But we now understand that radiation doesn't just kill cancer cells; it can profoundly modulate the immune system and the tumor microenvironment. We'll discuss how radiation can sometimes turn a "cold" tumor "hot," making it more visible to the immune system, and how this understanding is paving the way for powerful combination therapies, especially with immune checkpoint inhibitors.]]></itunes:summary><itunes:duration>1308</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>33</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E31: Molecular Techniques (Nucleic Acids &amp; Proteins)</title><link>https://www.spreaker.com/episode/radbio-e31-molecular-techniques-nucleic-acids-proteins--66333938</link><description><![CDATA[Welcome back to Rad Onc Smart Review! This is RadBio Edition, Episode 31: Molecular Techniques (Nucleic Acids &amp; Proteins).In our journey through radiobiology, we've talked a lot about DNA damage, repair, cell cycle, and how radiation impacts these processes. But how do we actually see and measure these molecular events in the lab? Today, we'll explore some of the fundamental tools molecular biologists use to study nucleic acids and proteins – techniques like PCR, various blotting methods, DNA sequencing, RFLP analysis, and assays for detecting DNA strand breaks like the Comet assay and gamma-H2AX foci staining. We'll also touch on ChIP, reporter assays, and the game-changing CRISPR-Cas9 gene editing technology. These are the workhorses that have allowed us to understand much of what we know about the molecular consequences of radiation and the inner workings of the cell.]]></description><guid isPermaLink="false">597f922f-7e59-4840-9c42-e73981947f99</guid><pubDate>Thu, 29 May 2025 21:32:07 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66333938/401245718_44100_2_4154ab57fe221.mp3" length="36840319" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! This is RadBio Edition, Episode 31: Molecular Techniques (Nucleic Acids &amp;amp; Proteins).In our journey through radiobiology, we've talked a lot about DNA damage, repair, cell cycle, and how radiation impacts these...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! This is RadBio Edition, Episode 31: Molecular Techniques (Nucleic Acids &amp; Proteins).In our journey through radiobiology, we've talked a lot about DNA damage, repair, cell cycle, and how radiation impacts these processes. But how do we actually see and measure these molecular events in the lab? Today, we'll explore some of the fundamental tools molecular biologists use to study nucleic acids and proteins – techniques like PCR, various blotting methods, DNA sequencing, RFLP analysis, and assays for detecting DNA strand breaks like the Comet assay and gamma-H2AX foci staining. We'll also touch on ChIP, reporter assays, and the game-changing CRISPR-Cas9 gene editing technology. These are the workhorses that have allowed us to understand much of what we know about the molecular consequences of radiation and the inner workings of the cell.]]></itunes:summary><itunes:duration>2303</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>31</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E30: Radiation Protection Limits &amp; Units (Part 2)</title><link>https://www.spreaker.com/episode/radbio-e30-radiation-protection-limits-units-part-2--66333927</link><description><![CDATA[Welcome back to Rad Onc Smart Review! Rad Bio Edition!This is Episode 30: Radiation Protection Limits &amp; Units (Part 2). In our last episode, we established the fundamental principles of radiation protection, differentiating between stochastic and deterministic effects and introducing basic radiation units like the Gray for absorbed dose. Today, we're taking the next step by exploring how these concepts translate into practical guidelines and dose limits. We'll focus on Equivalent Dose and Effective Dose, the crucial radiation and tissue weighting factors used in their calculation, and the specific annual dose limits recommended by regulatory bodies like the NCRP and ICRP for occupational, public, and fetal exposures. Understanding these limits is not just critical for board exams, but essential for ensuring safety in all environments where ionizing radiation is present.]]></description><guid isPermaLink="false">1ee13217-9613-4f96-af3a-d1b46c19816c</guid><pubDate>Thu, 29 May 2025 21:30:21 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66333927/401245667_44100_2_98062cf56f996.mp3" length="24385971" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review! Rad Bio Edition!This is Episode 30: Radiation Protection Limits &amp;amp; Units (Part 2). In our last episode, we established the fundamental principles of radiation protection, differentiating between stochastic and...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review! Rad Bio Edition!This is Episode 30: Radiation Protection Limits &amp; Units (Part 2). In our last episode, we established the fundamental principles of radiation protection, differentiating between stochastic and deterministic effects and introducing basic radiation units like the Gray for absorbed dose. Today, we're taking the next step by exploring how these concepts translate into practical guidelines and dose limits. We'll focus on Equivalent Dose and Effective Dose, the crucial radiation and tissue weighting factors used in their calculation, and the specific annual dose limits recommended by regulatory bodies like the NCRP and ICRP for occupational, public, and fetal exposures. Understanding these limits is not just critical for board exams, but essential for ensuring safety in all environments where ionizing radiation is present.]]></itunes:summary><itunes:duration>1525</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>30</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E29: Radiation Protection - Fundamental Principles and Basic Units</title><link>https://www.spreaker.com/episode/radbio-e29-radiation-protection-fundamental-principles-and-basic-units--66333929</link><description><![CDATA[This is Episode 29: Radiation Protection - Fundamental Principles and Basic Units.In our previous episodes, we’ve explored the multifaceted ways radiation interacts with biological systems, from the molecular dance of DNA damage and repair to the observable effects on cells, tissues, and even the developing embryo. Today, we're transitioning to a critical practical aspect: how we conceptualize and manage the risks associated with radiation. We'll lay the groundwork by clearly differentiating between the two major categories of radiation effects – stochastic and deterministic – as understanding this difference is fundamental to why we have specific protection strategies. We’ll then introduce the basic units used to quantify radiation: radioactivity, exposure, and absorbed dose. And finally, we'll outline the three universally accepted ethical principles that govern all radiation protection practices: justification, optimization (famously known as ALARA), and dose limitation. This episode sets the stage for understanding the more detailed dose limits we'll cover next time.]]></description><guid isPermaLink="false">74e1366c-8dd8-47d9-8efa-bfce06693510</guid><pubDate>Thu, 29 May 2025 21:29:03 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66333929/401245604_44100_2_93adc032f169f.mp3" length="21270085" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 29: Radiation Protection - Fundamental Principles and Basic Units.In our previous episodes, we’ve explored the multifaceted ways radiation interacts with biological systems, from the molecular dance of DNA damage and repair to the...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 29: Radiation Protection - Fundamental Principles and Basic Units.In our previous episodes, we’ve explored the multifaceted ways radiation interacts with biological systems, from the molecular dance of DNA damage and repair to the observable effects on cells, tissues, and even the developing embryo. Today, we're transitioning to a critical practical aspect: how we conceptualize and manage the risks associated with radiation. We'll lay the groundwork by clearly differentiating between the two major categories of radiation effects – stochastic and deterministic – as understanding this difference is fundamental to why we have specific protection strategies. We’ll then introduce the basic units used to quantify radiation: radioactivity, exposure, and absorbed dose. And finally, we'll outline the three universally accepted ethical principles that govern all radiation protection practices: justification, optimization (famously known as ALARA), and dose limitation. This episode sets the stage for understanding the more detailed dose limits we'll cover next time.]]></itunes:summary><itunes:duration>1330</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>29</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E28: Radiation Effects on Embryo &amp; Fetus</title><link>https://www.spreaker.com/episode/radbio-e28-radiation-effects-on-embryo-fetus--66333932</link><description><![CDATA[This is Episode 28: Radiation Effects on Embryo &amp; Fetus. In our previous episode, we explored the long-term stochastic risk of radiation-induced cancer. Today, we turn our attention to another critical area of radiation effects: the impact of in utero exposure on the developing embryo and fetus. This is a topic with profound clinical and ethical implications, and understanding the stage-dependent nature of these effects, the types of damage that can occur, and the relevant dose thresholds is paramount. We’ll see how effects like lethality, structural malformations, growth retardation, and severe central nervous system damage, particularly mental retardation, are strongly linked to the gestational age at the time of exposure and the radiation dose received. We'll also re-emphasize the distinction between these largely deterministic developmental effects and the stochastic risk of childhood cancer.]]></description><guid isPermaLink="false">e2f2b869-f23d-4ab8-8ac6-28de18e84b1f</guid><pubDate>Thu, 29 May 2025 21:27:41 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66333932/401245538_44100_2_2fa0213921982.mp3" length="22968672" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 28: Radiation Effects on Embryo &amp;amp; Fetus. In our previous episode, we explored the long-term stochastic risk of radiation-induced cancer. Today, we turn our attention to another critical area of radiation effects: the impact of in...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 28: Radiation Effects on Embryo &amp; Fetus. In our previous episode, we explored the long-term stochastic risk of radiation-induced cancer. Today, we turn our attention to another critical area of radiation effects: the impact of in utero exposure on the developing embryo and fetus. This is a topic with profound clinical and ethical implications, and understanding the stage-dependent nature of these effects, the types of damage that can occur, and the relevant dose thresholds is paramount. We’ll see how effects like lethality, structural malformations, growth retardation, and severe central nervous system damage, particularly mental retardation, are strongly linked to the gestational age at the time of exposure and the radiation dose received. We'll also re-emphasize the distinction between these largely deterministic developmental effects and the stochastic risk of childhood cancer.]]></itunes:summary><itunes:duration>1436</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>60</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E27: Heritable Effects of Radiation.</title><link>https://www.spreaker.com/episode/radbio-e27-heritable-effects-of-radiation--66333934</link><description><![CDATA[This is Episode 27: Heritable Effects of Radiation.In our last episode, we explored how radiation can act as a carcinogen, looking at risk models and latency periods. Today, we shift our focus from somatic effects to the potential impact of radiation on future generations – the heritable, or genetic, effects. We’ll define key concepts like Genetically Significant Dose and Doubling Dose, examine the landmark findings from studies of atomic bomb survivor offspring, and discuss the varying radiosensitivity of different germ cell stages.]]></description><guid isPermaLink="false">9129bb33-4df2-4ba7-8fe4-cacebbe00e8b</guid><pubDate>Thu, 29 May 2025 21:26:13 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66333934/401245486_44100_2_408f3c044504.mp3" length="20557883" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 27: Heritable Effects of Radiation.In our last episode, we explored how radiation can act as a carcinogen, looking at risk models and latency periods. Today, we shift our focus from somatic effects to the potential impact of radiation...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 27: Heritable Effects of Radiation.In our last episode, we explored how radiation can act as a carcinogen, looking at risk models and latency periods. Today, we shift our focus from somatic effects to the potential impact of radiation on future generations – the heritable, or genetic, effects. We’ll define key concepts like Genetically Significant Dose and Doubling Dose, examine the landmark findings from studies of atomic bomb survivor offspring, and discuss the varying radiosensitivity of different germ cell stages.]]></itunes:summary><itunes:duration>1285</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>27</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E26: Radiation Carcinogenesis &amp; Risk Models</title><link>https://www.spreaker.com/episode/radbio-e26-radiation-carcinogenesis-risk-models--66310351</link><description><![CDATA[In previous episodes, we've focused heavily on how radiation kills cancer cells and how normal tissues respond to therapeutic doses. Today, we shift our focus to a critical late effect of radiation exposure: the induction of cancer itself. Radiation, while a powerful tool against existing malignancies, is also a known carcinogen. We'll classify radiation carcinogenesis as a stochastic effect, explore the dose-response relationships for leukemia and solid tumors based largely on data from atomic bomb survivors, and understand the concept of latency periods. We'll also delve into the various factors that influence cancer risk from radiation and discuss the Linear No-Threshold (LNT) model, which underpins radiation protection philosophy, along with the DDREF concept used for risk extrapolation. Finally, we'll touch on the important clinical issue of secondary malignancy risk following radiotherapy.]]></description><guid isPermaLink="false">997d3476-9812-4f07-a853-8b9904c2e8f9</guid><pubDate>Wed, 28 May 2025 09:01:27 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66310351/401140840_44100_2_59c06e9c78814.mp3" length="30832992" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In previous episodes, we've focused heavily on how radiation kills cancer cells and how normal tissues respond to therapeutic doses. Today, we shift our focus to a critical late effect of radiation exposure: the induction of cancer itself. Radiation,...</itunes:subtitle><itunes:summary><![CDATA[In previous episodes, we've focused heavily on how radiation kills cancer cells and how normal tissues respond to therapeutic doses. Today, we shift our focus to a critical late effect of radiation exposure: the induction of cancer itself. Radiation, while a powerful tool against existing malignancies, is also a known carcinogen. We'll classify radiation carcinogenesis as a stochastic effect, explore the dose-response relationships for leukemia and solid tumors based largely on data from atomic bomb survivors, and understand the concept of latency periods. We'll also delve into the various factors that influence cancer risk from radiation and discuss the Linear No-Threshold (LNT) model, which underpins radiation protection philosophy, along with the DDREF concept used for risk extrapolation. Finally, we'll touch on the important clinical issue of secondary malignancy risk following radiotherapy.]]></itunes:summary><itunes:duration>1927</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>26</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E25: Radioprotectors &amp; Hyperthermia</title><link>https://www.spreaker.com/episode/radbio-e25-radioprotectors-hyperthermia--66310350</link><description><![CDATA[This is Episode 25: Radioprotectors &amp; Hyperthermia.In our previous discussions, we've explored ways to make tumor cells more vulnerable to radiation, particularly focusing on the challenge of hypoxia. Today, we're flipping the script slightly and also looking at strategies to enhance radiation’s effectiveness in different ways. First, we'll delve into radioprotectors, specifically compounds like Amifostine, which aim to shield our healthy normal tissues from radiation damage, potentially widening that all-important therapeutic window. Then, we'll turn up the heat and discuss hyperthermia – how using elevated temperatures can sensitize cancer cells to radiation, its biological effects, and the mechanisms like thermotolerance and heat shock proteins that come into play.]]></description><guid isPermaLink="false">ebbe4c07-3a5d-4be7-a15d-0cead03d5ee4</guid><pubDate>Wed, 28 May 2025 08:59:59 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66310350/401140785_44100_2_016f22bcf91a1.mp3" length="23356538" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 25: Radioprotectors &amp;amp; Hyperthermia.In our previous discussions, we've explored ways to make tumor cells more vulnerable to radiation, particularly focusing on the challenge of hypoxia. Today, we're flipping the script slightly and...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 25: Radioprotectors &amp; Hyperthermia.In our previous discussions, we've explored ways to make tumor cells more vulnerable to radiation, particularly focusing on the challenge of hypoxia. Today, we're flipping the script slightly and also looking at strategies to enhance radiation’s effectiveness in different ways. First, we'll delve into radioprotectors, specifically compounds like Amifostine, which aim to shield our healthy normal tissues from radiation damage, potentially widening that all-important therapeutic window. Then, we'll turn up the heat and discuss hyperthermia – how using elevated temperatures can sensitize cancer cells to radiation, its biological effects, and the mechanisms like thermotolerance and heat shock proteins that come into play.]]></itunes:summary><itunes:duration>1460</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>25</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E24: Radiosensitizers &amp; Bioreductive Drugs</title><link>https://www.spreaker.com/episode/radbio-e24-radiosensitizers-bioreductive-drugs--66310348</link><description><![CDATA[In our previous discussions, we've established that factors like tumor hypoxia can significantly limit the effectiveness of radiation therapy. Today, we're diving into strategies designed to overcome this and other forms of radioresistance. We'll explore agents that make tumor cells more vulnerable to radiation – the radiosensitizers. Specifically, we'll look at halogenated pyrimidines that get incorporated into DNA, and the electron-affinic nitroimidazoles that target hypoxic cells by mimicking oxygen. We’ll also touch upon how these nitroimidazoles can be used for imaging tumor hypoxia. Then, we'll shift to another class of agents, bioreductive drugs or hypoxic cytotoxins, like Tirapazamine, which are cleverly designed to become toxic specifically in the low-oxygen environment of tumors. Understanding these modifiers is key to appreciating ongoing efforts to enhance the therapeutic ratio in radiation oncology.]]></description><guid isPermaLink="false">561493e7-dce5-40d6-a5f6-f4896f67d08c</guid><pubDate>Wed, 28 May 2025 08:58:45 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66310348/401140715_44100_2_45bc1f1b4a4aa.mp3" length="17889632" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our previous discussions, we've established that factors like tumor hypoxia can significantly limit the effectiveness of radiation therapy. Today, we're diving into strategies designed to overcome this and other forms of radioresistance. We'll...</itunes:subtitle><itunes:summary><![CDATA[In our previous discussions, we've established that factors like tumor hypoxia can significantly limit the effectiveness of radiation therapy. Today, we're diving into strategies designed to overcome this and other forms of radioresistance. We'll explore agents that make tumor cells more vulnerable to radiation – the radiosensitizers. Specifically, we'll look at halogenated pyrimidines that get incorporated into DNA, and the electron-affinic nitroimidazoles that target hypoxic cells by mimicking oxygen. We’ll also touch upon how these nitroimidazoles can be used for imaging tumor hypoxia. Then, we'll shift to another class of agents, bioreductive drugs or hypoxic cytotoxins, like Tirapazamine, which are cleverly designed to become toxic specifically in the low-oxygen environment of tumors. Understanding these modifiers is key to appreciating ongoing efforts to enhance the therapeutic ratio in radiation oncology.]]></itunes:summary><itunes:duration>1118</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>24</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E23: Immunotherapy &amp; Radiation</title><link>https://www.spreaker.com/episode/radbio-e23-immunotherapy-radiation--66310352</link><description><![CDATA[For a long time, radiation therapy was primarily understood through its direct cytotoxic effects on tumor cells. But increasingly, we're recognizing that radiation is not just a local ablative tool; it's also a potent modulator of the tumor microenvironment and the immune system. Today, we're going to explore this fascinating interplay. We’ll define the intriguing abscopal and bystander effects, discuss how tumors try to evade our immune defenses, and identify the key immune cells that are our allies and those that can be foes in the fight against cancer. Crucially, we'll break down the PD-1/PD-L1 and CTLA-4 immune checkpoint pathways and then dive into the rationale and mechanisms for combining radiation with immune checkpoint inhibitors, including the concept of immunogenic cell death and Damage-Associated Molecular Patterns, or DAMPs. Finally, we'll list some of the checkpoint inhibitor drugs you're likely to encounter.]]></description><guid isPermaLink="false">0f22fc62-f63c-4a52-b06c-0356da068aa1</guid><pubDate>Wed, 28 May 2025 08:57:03 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66310352/401140670_44100_2_c0a5b6b0113ed.mp3" length="28903274" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>For a long time, radiation therapy was primarily understood through its direct cytotoxic effects on tumor cells. But increasingly, we're recognizing that radiation is not just a local ablative tool; it's also a potent modulator of the tumor...</itunes:subtitle><itunes:summary><![CDATA[For a long time, radiation therapy was primarily understood through its direct cytotoxic effects on tumor cells. But increasingly, we're recognizing that radiation is not just a local ablative tool; it's also a potent modulator of the tumor microenvironment and the immune system. Today, we're going to explore this fascinating interplay. We’ll define the intriguing abscopal and bystander effects, discuss how tumors try to evade our immune defenses, and identify the key immune cells that are our allies and those that can be foes in the fight against cancer. Crucially, we'll break down the PD-1/PD-L1 and CTLA-4 immune checkpoint pathways and then dive into the rationale and mechanisms for combining radiation with immune checkpoint inhibitors, including the concept of immunogenic cell death and Damage-Associated Molecular Patterns, or DAMPs. Finally, we'll list some of the checkpoint inhibitor drugs you're likely to encounter.]]></itunes:summary><itunes:duration>1807</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>23</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E22B:Chemo+RT - Synergy &amp; Targeted Agents.</title><link>https://www.spreaker.com/episode/radbio-e22b-chemo-rt-synergy-targeted-agents--66310349</link><description><![CDATA[In our last episode, we laid out the broad principles of combining chemotherapy with radiation and surveyed the major classes of traditional cytotoxic drugs. Today, we're taking a closer look at the "why" and "how" of these combinations. We'll explore which specific chemotherapy agents are known to work synergistically with radiation, how their cell cycle specificity plays into this partnership, and importantly, the normal tissue toxicities that can be exacerbated. Then, we’ll shift gears to the exciting realm of molecularly targeted therapies, identifying key targets like EGFR, HER2, VEGF, and PARP, and discussing how agents like Cetuximab, Trastuzumab, Bevacizumab, and PARP inhibitors like Olaparib interact with radiation. We’ll cap it off with a crucial concept: synthetic lethality, particularly as it relates to PARP inhibitors and BRCA mutations.]]></description><guid isPermaLink="false">f04d6a66-ea0f-4ef3-aaf9-88f270883f8b</guid><pubDate>Wed, 28 May 2025 08:55:34 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66310349/401140612_44100_2_61e52e8ed5e81.mp3" length="20953690" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we laid out the broad principles of combining chemotherapy with radiation and surveyed the major classes of traditional cytotoxic drugs. Today, we're taking a closer look at the "why" and "how" of these combinations. We'll explore...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we laid out the broad principles of combining chemotherapy with radiation and surveyed the major classes of traditional cytotoxic drugs. Today, we're taking a closer look at the "why" and "how" of these combinations. We'll explore which specific chemotherapy agents are known to work synergistically with radiation, how their cell cycle specificity plays into this partnership, and importantly, the normal tissue toxicities that can be exacerbated. Then, we’ll shift gears to the exciting realm of molecularly targeted therapies, identifying key targets like EGFR, HER2, VEGF, and PARP, and discussing how agents like Cetuximab, Trastuzumab, Bevacizumab, and PARP inhibitors like Olaparib interact with radiation. We’ll cap it off with a crucial concept: synthetic lethality, particularly as it relates to PARP inhibitors and BRCA mutations.]]></itunes:summary><itunes:duration>1310</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>22</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E22A: Chemo+RT - Principles &amp; Drug Classes.</title><link>https://www.spreaker.com/episode/radbio-e22a-chemo-rt-principles-drug-classes--66213190</link><description><![CDATA[This is Episode 22, Part A: Chemo+RT - Principles &amp; Drug Classes.For decades, radiation therapy has been a cornerstone of cancer treatment, offering potent local control. But as we know, cancer can be a systemic disease, and sometimes radiation alone isn't enough, or we want to make its local effects even more powerful. That’s where combining it with chemotherapy comes into play. Today, we're going to lay the foundational principles for understanding how these two powerful modalities work together. We'll explore the basic rationale for combining them, define the different ways their effects can interact – think synergy, additivity, and antagonism – and then we’ll take a tour through the major classes of chemotherapeutic agents, focusing on their mechanisms of action and key examples you’ll encounter in chemoradiation regimens.]]></description><guid isPermaLink="false">8718cc82-a205-4b9f-bce1-afcd6193ab79</guid><pubDate>Thu, 22 May 2025 21:35:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66213190/400828317_44100_2_b5f37dffb3145.mp3" length="18757733" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 22, Part A: Chemo+RT - Principles &amp;amp; Drug Classes.For decades, radiation therapy has been a cornerstone of cancer treatment, offering potent local control. But as we know, cancer can be a systemic disease, and sometimes radiation...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 22, Part A: Chemo+RT - Principles &amp; Drug Classes.For decades, radiation therapy has been a cornerstone of cancer treatment, offering potent local control. But as we know, cancer can be a systemic disease, and sometimes radiation alone isn't enough, or we want to make its local effects even more powerful. That’s where combining it with chemotherapy comes into play. Today, we're going to lay the foundational principles for understanding how these two powerful modalities work together. We'll explore the basic rationale for combining them, define the different ways their effects can interact – think synergy, additivity, and antagonism – and then we’ll take a tour through the major classes of chemotherapeutic agents, focusing on their mechanisms of action and key examples you’ll encounter in chemoradiation regimens.]]></itunes:summary><itunes:duration>1173</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>22</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E21B: Advanced Modalities - IMRT &amp; FLASH</title><link>https://www.spreaker.com/episode/radbio-e21b-advanced-modalities-imrt-flash--66213174</link><description><![CDATA[This is Episode 21, Part B: Advanced Modalities - IMRT &amp; FLASH.In our previous episode, we explored the exciting world of particle therapy, looking at how protons and heavy ions like carbon aim to improve treatment by precisely targeting tumors. Today, we continue our journey into advanced radiotherapy modalities, but we’ll shift our focus back to photon-based treatments and a very novel high-dose-rate concept. First, we'll discuss Intensity-Modulated Radiation Therapy, or IMRT, a cornerstone of modern radiotherapy, and examine some of its important radiobiological considerations, particularly regarding integral dose and the risk of secondary cancers. Then, we'll jump to the cutting edge with FLASH radiotherapy, a technique delivering ultra-high dose rates with the tantalizing promise of significantly sparing normal tissues while maintaining tumor control.]]></description><guid isPermaLink="false">09f8180d-7e95-4763-9fdc-968f6e30fc75</guid><pubDate>Thu, 22 May 2025 21:33:53 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66213174/400828154_44100_2_6ba8ca016d686.mp3" length="24875401" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 21, Part B: Advanced Modalities - IMRT &amp;amp; FLASH.In our previous episode, we explored the exciting world of particle therapy, looking at how protons and heavy ions like carbon aim to improve treatment by precisely targeting tumors....</itunes:subtitle><itunes:summary><![CDATA[This is Episode 21, Part B: Advanced Modalities - IMRT &amp; FLASH.In our previous episode, we explored the exciting world of particle therapy, looking at how protons and heavy ions like carbon aim to improve treatment by precisely targeting tumors. Today, we continue our journey into advanced radiotherapy modalities, but we’ll shift our focus back to photon-based treatments and a very novel high-dose-rate concept. First, we'll discuss Intensity-Modulated Radiation Therapy, or IMRT, a cornerstone of modern radiotherapy, and examine some of its important radiobiological considerations, particularly regarding integral dose and the risk of secondary cancers. Then, we'll jump to the cutting edge with FLASH radiotherapy, a technique delivering ultra-high dose rates with the tantalizing promise of significantly sparing normal tissues while maintaining tumor control.]]></itunes:summary><itunes:duration>1555</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>21</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E21A: Advanced Modalities - Particle Therapy.</title><link>https://www.spreaker.com/episode/radbio-e21a-advanced-modalities-particle-therapy--66208675</link><description><![CDATA[This is Episode 21, Part A: Advanced Modalities - Particle Therapy.In our previous episodes, we've explored the radiobiology of conventional photon therapy, including fractionation and dose rate effects, and we've touched on brachytherapy. Today, we're venturing into the realm of particle therapy, focusing on charged particles like protons and heavier ions, particularly carbon ions. These modalities offer distinct physical and biological properties compared to photons. The main allure is their unique way of depositing dose, characterized by the Bragg peak, which promises better targeting of tumors and sparing of normal tissues. We'll dissect the advantages of this dose distribution, delve into concepts like Linear Energy Transfer (LET) and Relative Biological Effectiveness (RBE) as they apply to these particles, and explore the phenomenon of nuclear fragmentation. Finally, we’ll compare the potential benefits and challenges of proton versus carbon ion therapy.]]></description><guid isPermaLink="false">8c0949fa-c28d-48d2-9d2a-6776f8ef4257</guid><pubDate>Thu, 22 May 2025 18:17:23 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66208675/400816259_44100_2_50545ea2124f9.mp3" length="16250396" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 21, Part A: Advanced Modalities - Particle Therapy.In our previous episodes, we've explored the radiobiology of conventional photon therapy, including fractionation and dose rate effects, and we've touched on brachytherapy. Today,...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 21, Part A: Advanced Modalities - Particle Therapy.In our previous episodes, we've explored the radiobiology of conventional photon therapy, including fractionation and dose rate effects, and we've touched on brachytherapy. Today, we're venturing into the realm of particle therapy, focusing on charged particles like protons and heavier ions, particularly carbon ions. These modalities offer distinct physical and biological properties compared to photons. The main allure is their unique way of depositing dose, characterized by the Bragg peak, which promises better targeting of tumors and sparing of normal tissues. We'll dissect the advantages of this dose distribution, delve into concepts like Linear Energy Transfer (LET) and Relative Biological Effectiveness (RBE) as they apply to these particles, and explore the phenomenon of nuclear fragmentation. Finally, we’ll compare the potential benefits and challenges of proton versus carbon ion therapy.]]></itunes:summary><itunes:duration>1016</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>21</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P20: Brachytherapy Radiobiology</title><link>https://www.spreaker.com/episode/physics-episode-p20-brachytherapy-radiobiology--66198521</link><description><![CDATA[Welcome back to Rad Onc Smart Review, Radiation Biology edition is Episode 20: Brachytherapy Radiobiology. In our previous discussions, we've explored the principles of fractionation, primarily in the context of external beam radiotherapy, where doses are delivered in discrete, short bursts. Today, we're shifting gears to a fascinating and very different world of radiation delivery: brachytherapy. The term "brachy" comes from the Greek word for "short," and that’s exactly what it is – short-range therapy, where radioactive sources are placed directly into or very close to the tumor. This proximity allows for a highly conformal, high-dose treatment to the tumor while rapidly sparing surrounding normal tissues. But it also introduces unique radiobiological considerations due to the continuous, and often low-dose-rate, exposure. We'll unravel how principles like the LQ model, repair, and dose rate apply in this setting, compare low dose rate (LDR) with high dose rate (HDR) brachytherapy, look at the isotopes commonly used, and discuss the clinical advantages of that characteristic steep dose gradient.]]></description><guid isPermaLink="false">db3d8e30-8da4-4845-b20e-73cda74c7d2f</guid><pubDate>Thu, 22 May 2025 06:41:54 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66198521/400780248_44100_2_00a3b6862f969.mp3" length="21046477" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, Radiation Biology edition is Episode 20: Brachytherapy Radiobiology. In our previous discussions, we've explored the principles of fractionation, primarily in the context of external beam radiotherapy, where doses...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, Radiation Biology edition is Episode 20: Brachytherapy Radiobiology. In our previous discussions, we've explored the principles of fractionation, primarily in the context of external beam radiotherapy, where doses are delivered in discrete, short bursts. Today, we're shifting gears to a fascinating and very different world of radiation delivery: brachytherapy. The term "brachy" comes from the Greek word for "short," and that’s exactly what it is – short-range therapy, where radioactive sources are placed directly into or very close to the tumor. This proximity allows for a highly conformal, high-dose treatment to the tumor while rapidly sparing surrounding normal tissues. But it also introduces unique radiobiological considerations due to the continuous, and often low-dose-rate, exposure. We'll unravel how principles like the LQ model, repair, and dose rate apply in this setting, compare low dose rate (LDR) with high dose rate (HDR) brachytherapy, look at the isotopes commonly used, and discuss the clinical advantages of that characteristic steep dose gradient.]]></itunes:summary><itunes:duration>1316</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>20</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E19: Altered Fractionation - Hyperfractionation, Accelerated Radiotherapy, and CHART</title><link>https://www.spreaker.com/episode/radbio-e19-altered-fractionation-hyperfractionation-accelerated-radiotherapy-and-chart--66198513</link><description><![CDATA[This is Episode 19: Altered Fractionation - Hyperfractionation, Accelerated Radiotherapy, and CHART.In our previous episode, we mastered the Linear-Quadratic model and the concept of Biological Effective Dose, tools that allow us to compare different radiation schedules. We learned that early and late-responding tissues, as well as tumors, have different sensitivities to changes in fraction size, largely dictated by their α/β ratios. Today, we're going to build directly on that knowledge by exploring how these principles are applied to design altered fractionation schedules. We’ll unpack strategies like hyperfractionation, designed to spare late normal tissue effects, and accelerated radiotherapy, aimed at combating tumor repopulation. We'll also discuss the critical importance of the time between fractions in multi-fraction-per-day regimens and look at a famous example of combining these concepts in the CHART protocol.]]></description><guid isPermaLink="false">a7e8cf4a-68c4-4171-b933-41db2bc2013a</guid><pubDate>Thu, 22 May 2025 06:35:33 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66198513/400780074_44100_2_2ce61cae2912e.mp3" length="22577462" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 19: Altered Fractionation - Hyperfractionation, Accelerated Radiotherapy, and CHART.In our previous episode, we mastered the Linear-Quadratic model and the concept of Biological Effective Dose, tools that allow us to compare different...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 19: Altered Fractionation - Hyperfractionation, Accelerated Radiotherapy, and CHART.In our previous episode, we mastered the Linear-Quadratic model and the concept of Biological Effective Dose, tools that allow us to compare different radiation schedules. We learned that early and late-responding tissues, as well as tumors, have different sensitivities to changes in fraction size, largely dictated by their α/β ratios. Today, we're going to build directly on that knowledge by exploring how these principles are applied to design altered fractionation schedules. We’ll unpack strategies like hyperfractionation, designed to spare late normal tissue effects, and accelerated radiotherapy, aimed at combating tumor repopulation. We'll also discuss the critical importance of the time between fractions in multi-fraction-per-day regimens and look at a famous example of combining these concepts in the CHART protocol.]]></itunes:summary><itunes:duration>1411</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>19</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E18C: Fractionation - The LQ Model, BED, and Isoeffect Curves</title><link>https://www.spreaker.com/episode/radbio-e18c-fractionation-the-lq-model-bed-and-isoeffect-curves--66198522</link><description><![CDATA[This is Episode 18, Part C: Fractionation - The LQ Model, BED, and Isoeffect Curves.In our previous discussions on fractionation, we’ve explored the "4 R's" and the impact of dose rate. These concepts help explain why fractionated radiotherapy works. Now, we need a way to quantify these effects and compare different fractionation schedules. This is where the Linear-Quadratic, or LQ, model comes into play. Today, we'll revisit the LQ model, delve deep into the meaning of the α/β ratio, and learn how to use it to calculate the Biological Effective Dose (BED) and Equivalent Dose in 2 Gy fractions (EQD2). We'll also learn to interpret isoeffect curves, which visually represent how different tissues respond to changes in fractionation. And finally, we’ll briefly touch upon some of the limitations of this widely used model.]]></description><guid isPermaLink="false">2251c623-f8ef-46ee-bd0b-471c924c3cef</guid><pubDate>Thu, 22 May 2025 06:31:20 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66198522/400779927_44100_2_c10508a702bbd.mp3" length="20811166" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 18, Part C: Fractionation - The LQ Model, BED, and Isoeffect Curves.In our previous discussions on fractionation, we’ve explored the "4 R's" and the impact of dose rate. These concepts help explain why fractionated radiotherapy works....</itunes:subtitle><itunes:summary><![CDATA[This is Episode 18, Part C: Fractionation - The LQ Model, BED, and Isoeffect Curves.In our previous discussions on fractionation, we’ve explored the "4 R's" and the impact of dose rate. These concepts help explain why fractionated radiotherapy works. Now, we need a way to quantify these effects and compare different fractionation schedules. This is where the Linear-Quadratic, or LQ, model comes into play. Today, we'll revisit the LQ model, delve deep into the meaning of the α/β ratio, and learn how to use it to calculate the Biological Effective Dose (BED) and Equivalent Dose in 2 Gy fractions (EQD2). We'll also learn to interpret isoeffect curves, which visually represent how different tissues respond to changes in fractionation. And finally, we’ll briefly touch upon some of the limitations of this widely used model.]]></itunes:summary><itunes:duration>1301</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E18B: Fractionation - Dose Rate Effects</title><link>https://www.spreaker.com/episode/radbio-e18b-fractionation-dose-rate-effects--66197991</link><description><![CDATA[This is Episode 18, Part B: Fractionation - Dose Rate Effects.In our last episode, we laid the groundwork by exploring the "Four Rs of Radiobiology" – Repair, Reassortment, Repopulation, and Reoxygenation – which explain the benefits of delivering radiation in multiple fractions. Today, we're going to zoom in on another critical parameter that profoundly influences biological outcome: the dose rate, or how quickly a given dose of radiation is delivered. We'll see how, in general, slower delivery allows for more cellular repair, leading to increased survival. But we'll also uncover a fascinating exception known as the "Inverse Dose Rate Effect" and explore why some cells actually become more sensitive at certain low dose rates. Finally, we'll touch upon how Linear Energy Transfer, or L E T, interacts with these dose rate]]></description><guid isPermaLink="false">d7190ce4-8630-4826-ad3d-f0338c11988f</guid><pubDate>Thu, 22 May 2025 05:39:02 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66197991/400778104_44100_2_3f9433f1e2e2d.mp3" length="15380623" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 18, Part B: Fractionation - Dose Rate Effects.In our last episode, we laid the groundwork by exploring the "Four Rs of Radiobiology" – Repair, Reassortment, Repopulation, and Reoxygenation – which explain the benefits of delivering...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 18, Part B: Fractionation - Dose Rate Effects.In our last episode, we laid the groundwork by exploring the "Four Rs of Radiobiology" – Repair, Reassortment, Repopulation, and Reoxygenation – which explain the benefits of delivering radiation in multiple fractions. Today, we're going to zoom in on another critical parameter that profoundly influences biological outcome: the dose rate, or how quickly a given dose of radiation is delivered. We'll see how, in general, slower delivery allows for more cellular repair, leading to increased survival. But we'll also uncover a fascinating exception known as the "Inverse Dose Rate Effect" and explore why some cells actually become more sensitive at certain low dose rates. Finally, we'll touch upon how Linear Energy Transfer, or L E T, interacts with these dose rate]]></itunes:summary><itunes:duration>962</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E18A:Fractionation - The Four Rs of Radiobiology</title><link>https://www.spreaker.com/episode/radbio-e18a-fractionation-the-four-rs-of-radiobiology--66198050</link><description><![CDATA[This is Episode 18, Part A: Fractionation - The Four Rs of Radiobiology.In our last episode, we discussed the therapeutic ratio and the ongoing quest to predict how tumors and normal tissues will respond to radiation. One of the oldest and still most powerful strategies we use to widen this therapeutic window – to maximize tumor kill while minimizing normal tissue damage – is fractionation. That means instead of giving one massive dose of radiation, we divide it into multiple smaller doses delivered over days or weeks. The success of fractionated radiotherapy isn't just a happy accident; it's deeply rooted in fundamental radiobiological principles. Today, we're diving into the cornerstone of this understanding: the "Four Rs" of radiobiology. These are Repair, Reassortment, Repopulation, and Reoxygenation. Let’s unpack each one.]]></description><guid isPermaLink="false">fffeb04c-3aab-4a19-b027-cb1025fd4bdd</guid><pubDate>Thu, 22 May 2025 05:37:53 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66198050/400778032_44100_2_1209a499da16d.mp3" length="17531858" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 18, Part A: Fractionation - The Four Rs of Radiobiology.In our last episode, we discussed the therapeutic ratio and the ongoing quest to predict how tumors and normal tissues will respond to radiation. One of the oldest and still most...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 18, Part A: Fractionation - The Four Rs of Radiobiology.In our last episode, we discussed the therapeutic ratio and the ongoing quest to predict how tumors and normal tissues will respond to radiation. One of the oldest and still most powerful strategies we use to widen this therapeutic window – to maximize tumor kill while minimizing normal tissue damage – is fractionation. That means instead of giving one massive dose of radiation, we divide it into multiple smaller doses delivered over days or weeks. The success of fractionated radiotherapy isn't just a happy accident; it's deeply rooted in fundamental radiobiological principles. Today, we're diving into the cornerstone of this understanding: the "Four Rs" of radiobiology. These are Repair, Reassortment, Repopulation, and Reoxygenation. Let’s unpack each one.]]></itunes:summary><itunes:duration>1096</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>18</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode E17: Therapeutic Ratio &amp; Predictive Assays</title><link>https://www.spreaker.com/episode/physics-episode-e17-therapeutic-ratio-predictive-assays--66198058</link><description><![CDATA[This is Episode 17: Therapeutic Ratio &amp; Predictive Assays. In our previous episodes, we've explored how radiation interacts with cells and tissues, the different types of damage it causes, and how cells attempt to repair that damage. We've also seen that different tissues, both normal and malignant, respond differently to radiation. The ultimate goal in radiation therapy is to deliver a dose that is high enough to eradicate all cancer cells while minimizing damage to surrounding healthy normal tissues. This delicate balance is what we call the therapeutic ratio. Today, we're going to define this crucial concept, look at how it's visualized using Tumor Control Probability and Normal Tissue Complication Probability curves, explore the factors that influence these probabilities, and discuss assays that aim to predict these responses, thereby helping us personalize and optimize treatment for our patients. We'll also touch upon how radioprotectors and radiosensitizers aim to improve this therapeutic ratio.]]></description><guid isPermaLink="false">06e06e9e-fa42-4106-9233-ad83618710eb</guid><pubDate>Thu, 22 May 2025 05:32:40 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66198058/400777900_44100_2_bca16908a4954.mp3" length="29288214" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 17: Therapeutic Ratio &amp;amp; Predictive Assays. In our previous episodes, we've explored how radiation interacts with cells and tissues, the different types of damage it causes, and how cells attempt to repair that damage. We've also...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 17: Therapeutic Ratio &amp; Predictive Assays. In our previous episodes, we've explored how radiation interacts with cells and tissues, the different types of damage it causes, and how cells attempt to repair that damage. We've also seen that different tissues, both normal and malignant, respond differently to radiation. The ultimate goal in radiation therapy is to deliver a dose that is high enough to eradicate all cancer cells while minimizing damage to surrounding healthy normal tissues. This delicate balance is what we call the therapeutic ratio. Today, we're going to define this crucial concept, look at how it's visualized using Tumor Control Probability and Normal Tissue Complication Probability curves, explore the factors that influence these probabilities, and discuss assays that aim to predict these responses, thereby helping us personalize and optimize treatment for our patients. We'll also touch upon how radioprotectors and radiosensitizers aim to improve this therapeutic ratio.]]></itunes:summary><itunes:duration>1831</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E16: Normal Tissue Mechanisms: Functional Subunits, Cytokines, and Fibrosis</title><link>https://www.spreaker.com/episode/radbio-e16-normal-tissue-mechanisms-functional-subunits-cytokines-and-fibrosis--66196499</link><description><![CDATA[This is Episode 16: Normal Tissue Mechanisms: Functional Subunits, Cytokines, and Fibrosis.In our previous episodes covering normal tissue effects, we've seen how different organs respond to radiation over various timescales, manifesting as either early or late toxicities. We've also touched upon the idea that the structure and organization of a tissue, along with complex cellular signaling, profoundly influence these responses. Today, we're going to delve deeper into the "how" and "why" behind these normal tissue reactions. We’ll explore the concept of Functional Subunits, or FSUs, and how their arrangement dictates an organ's tolerance and susceptibility to volume effects. We'll also revisit the distinction between early and late-responding tissues through the lens of their proliferative organization. Finally, we'll unravel the complex molecular cascade, with a special focus on key cytokines like TGF-beta, that leads to one of the most dreaded late effects: radiation-induced fibrosis.]]></description><guid isPermaLink="false">72d73f4f-f888-4642-98c9-c5dbfe82f13d</guid><pubDate>Thu, 22 May 2025 03:11:53 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66196499/400773410_44100_2_af6b42f6c333b.mp3" length="23493210" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 16: Normal Tissue Mechanisms: Functional Subunits, Cytokines, and Fibrosis.In our previous episodes covering normal tissue effects, we've seen how different organs respond to radiation over various timescales, manifesting as either...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 16: Normal Tissue Mechanisms: Functional Subunits, Cytokines, and Fibrosis.In our previous episodes covering normal tissue effects, we've seen how different organs respond to radiation over various timescales, manifesting as either early or late toxicities. We've also touched upon the idea that the structure and organization of a tissue, along with complex cellular signaling, profoundly influence these responses. Today, we're going to delve deeper into the "how" and "why" behind these normal tissue reactions. We’ll explore the concept of Functional Subunits, or FSUs, and how their arrangement dictates an organ's tolerance and susceptibility to volume effects. We'll also revisit the distinction between early and late-responding tissues through the lens of their proliferative organization. Finally, we'll unravel the complex molecular cascade, with a special focus on key cytokines like TGF-beta, that leads to one of the most dreaded late effects: radiation-induced fibrosis.]]></itunes:summary><itunes:duration>1469</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>16</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E15D: Normal Tissues - Late Effects on Gonads and Bone.</title><link>https://www.spreaker.com/episode/radbio-e15d-normal-tissues-late-effects-on-gonads-and-bone--66196496</link><description><![CDATA[This is Episode 15, Part D: Normal Tissues - Late Effects on Gonads and Bone.In our previous episodes, we've explored the late detrimental effects of radiation on critical organs like the central nervous system, lungs, heart, and kidneys. Today, we turn our attention to two other vital tissue systems that can suffer long-term consequences from radiation exposure: the gonads – testes and ovaries – and bone, distinguishing between its response when actively growing versus when it is mature. These effects can have profound impacts on fertility, hormonal balance, growth, and skeletal integrity.]]></description><guid isPermaLink="false">105a52a2-f3d3-48f3-bc74-bcfc61713553</guid><pubDate>Thu, 22 May 2025 02:59:35 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66196496/400772953_44100_2_cb6c838a112c.mp3" length="17249318" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 15, Part D: Normal Tissues - Late Effects on Gonads and Bone.In our previous episodes, we've explored the late detrimental effects of radiation on critical organs like the central nervous system, lungs, heart, and kidneys. Today, we...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 15, Part D: Normal Tissues - Late Effects on Gonads and Bone.In our previous episodes, we've explored the late detrimental effects of radiation on critical organs like the central nervous system, lungs, heart, and kidneys. Today, we turn our attention to two other vital tissue systems that can suffer long-term consequences from radiation exposure: the gonads – testes and ovaries – and bone, distinguishing between its response when actively growing versus when it is mature. These effects can have profound impacts on fertility, hormonal balance, growth, and skeletal integrity.]]></itunes:summary><itunes:duration>1078</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E15C: Normal Tissues - Late Effects (Heart, Kidney, and Lens)</title><link>https://www.spreaker.com/episode/radbio-e15c-normal-tissues-late-effects-heart-kidney-and-lens--66196498</link><description><![CDATA[This is Episode 15, Part C: Normal Tissues - Late Effects (Heart, Kidney, and Lens).In our previous episode, we discussed the late effects of radiation on the central nervous system and the lungs. Today, we continue our exploration of late normal tissue toxicities by focusing on three more critical organs: the heart, the kidneys, and the lens of the eye. These organs, while perhaps not always dose-limiting in the same way as the spinal cord, can suffer significant long-term consequences from radiation exposure, impacting patient quality of life and even survival. We'll look at the specific types of damage radiation can cause in these tissues, the underlying mechanisms, and their clinical implications.]]></description><guid isPermaLink="false">aa0b664d-8687-4376-81da-fbe65d7c9c2a</guid><pubDate>Thu, 22 May 2025 02:41:45 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66196498/400772337_44100_2_d60f21abb87db.mp3" length="23293008" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 15, Part C: Normal Tissues - Late Effects (Heart, Kidney, and Lens).In our previous episode, we discussed the late effects of radiation on the central nervous system and the lungs. Today, we continue our exploration of late normal...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 15, Part C: Normal Tissues - Late Effects (Heart, Kidney, and Lens).In our previous episode, we discussed the late effects of radiation on the central nervous system and the lungs. Today, we continue our exploration of late normal tissue toxicities by focusing on three more critical organs: the heart, the kidneys, and the lens of the eye. These organs, while perhaps not always dose-limiting in the same way as the spinal cord, can suffer significant long-term consequences from radiation exposure, impacting patient quality of life and even survival. We'll look at the specific types of damage radiation can cause in these tissues, the underlying mechanisms, and their clinical implications.]]></itunes:summary><itunes:duration>1456</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E15B:Normal Tissues - Late Effects, focusing on the Central Nervous System and Lungs.</title><link>https://www.spreaker.com/episode/radbio-e15b-normal-tissues-late-effects-focusing-on-the-central-nervous-system-and-lungs--66196497</link><description><![CDATA[In our previous episode, we explored the acute, or early, effects of radiation on rapidly dividing normal tissues like the skin, gut, and bone marrow. These effects, while often distressing, are typically transient and heal. Today, we shift our attention to a different category of radiation injury: late effects. These complications can manifest months or even years after the completion of radiotherapy and are often progressive and irreversible, posing significant long-term challenges for our patients. We'll specifically delve into the late effects on two critical organ systems: the central nervous system (CNS) – including the brain and spinal cord – and the lungs.]]></description><guid isPermaLink="false">fc167386-16e9-4aa6-87f9-c209bcd594c4</guid><pubDate>Thu, 22 May 2025 02:31:58 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66196497/400771695_44100_2_8c491e1f31aee.mp3" length="22483421" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our previous episode, we explored the acute, or early, effects of radiation on rapidly dividing normal tissues like the skin, gut, and bone marrow. These effects, while often distressing, are typically transient and heal. Today, we shift our...</itunes:subtitle><itunes:summary><![CDATA[In our previous episode, we explored the acute, or early, effects of radiation on rapidly dividing normal tissues like the skin, gut, and bone marrow. These effects, while often distressing, are typically transient and heal. Today, we shift our attention to a different category of radiation injury: late effects. These complications can manifest months or even years after the completion of radiotherapy and are often progressive and irreversible, posing significant long-term challenges for our patients. We'll specifically delve into the late effects on two critical organ systems: the central nervous system (CNS) – including the brain and spinal cord – and the lungs.]]></itunes:summary><itunes:duration>1406</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E15A: Normal Tissues - Early Effects on Skin, Gut, and Bone Marrow.</title><link>https://www.spreaker.com/episode/radbio-e15a-normal-tissues-early-effects-on-skin-gut-and-bone-marrow--66191676</link><description><![CDATA[In our last episode, we discussed the dramatic and often devastating consequences of Total Body Irradiation, focusing on the acute radiation syndromes. Today, we're narrowing our focus to the specific early, or acute, effects of radiation on some of the most critical rapidly renewing normal tissues: the skin, the gastrointestinal tract, often called the G I tract, and the hematopoietic system, often referred to as bone marrow. These are the tissues that often show the first signs of radiation injury during a course of radiotherapy, and understanding their response is absolutely fundamental to our clinical practice.]]></description><guid isPermaLink="false">013c4583-9597-4990-9fd2-d52119ba3f1e</guid><pubDate>Wed, 21 May 2025 19:25:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66191676/400748927_44100_2_4208ed76c4bb9.mp3" length="20046301" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episode, we discussed the dramatic and often devastating consequences of Total Body Irradiation, focusing on the acute radiation syndromes. Today, we're narrowing our focus to the specific early, or acute, effects of radiation on some of...</itunes:subtitle><itunes:summary><![CDATA[In our last episode, we discussed the dramatic and often devastating consequences of Total Body Irradiation, focusing on the acute radiation syndromes. Today, we're narrowing our focus to the specific early, or acute, effects of radiation on some of the most critical rapidly renewing normal tissues: the skin, the gastrointestinal tract, often called the G I tract, and the hematopoietic system, often referred to as bone marrow. These are the tissues that often show the first signs of radiation injury during a course of radiotherapy, and understanding their response is absolutely fundamental to our clinical practice.]]></itunes:summary><itunes:duration>1253</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E14: Total Body Irradiation (TBI) Syndromes.</title><link>https://www.spreaker.com/episode/radbio-e14-total-body-irradiation-tbi-syndromes--66191667</link><description><![CDATA[This is Episode 14, Total Body Irradiation (TBI) Syndromes. Today, we're shifting our focus from the cellular level to the effects of radiation on the whole organism, specifically when the entire body is exposed to a significant dose of radiation. This can happen in radiation accidents, nuclear incidents, or unfortunately, in scenarios involving radiological terrorism, but also, in a controlled manner, during conditioning regimens for bone marrow transplantation. Understanding the sequence of events and the different syndromes that can arise is critical, not just for exam purposes, but because as radiation oncologists, we are often considered the first line of clinical defense and expertise in such emergencies. We'll be looking at the immediate symptoms, known as the prodromal syndrome, and then diving into the major acute radiation syndromes: hematopoietic, gastrointestinal, and cerebrovascular, including their dose thresholds, timelines, and the underlying organ system failures that lead to them. We will also discuss the LD50/60, or the lethal dose for 50% of an exposed human population, and the potential for late complications like pulmonary syndrome in survivors.]]></description><guid isPermaLink="false">cb710b12-629d-48b4-bc62-ace3003c8875</guid><pubDate>Wed, 21 May 2025 19:20:16 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66191667/400748402_44100_2_795ff7414f256.mp3" length="16109543" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 14, Total Body Irradiation (TBI) Syndromes. Today, we're shifting our focus from the cellular level to the effects of radiation on the whole organism, specifically when the entire body is exposed to a significant dose of radiation....</itunes:subtitle><itunes:summary><![CDATA[This is Episode 14, Total Body Irradiation (TBI) Syndromes. Today, we're shifting our focus from the cellular level to the effects of radiation on the whole organism, specifically when the entire body is exposed to a significant dose of radiation. This can happen in radiation accidents, nuclear incidents, or unfortunately, in scenarios involving radiological terrorism, but also, in a controlled manner, during conditioning regimens for bone marrow transplantation. Understanding the sequence of events and the different syndromes that can arise is critical, not just for exam purposes, but because as radiation oncologists, we are often considered the first line of clinical defense and expertise in such emergencies. We'll be looking at the immediate symptoms, known as the prodromal syndrome, and then diving into the major acute radiation syndromes: hematopoietic, gastrointestinal, and cerebrovascular, including their dose thresholds, timelines, and the underlying organ system failures that lead to them. We will also discuss the LD50/60, or the lethal dose for 50% of an exposed human population, and the potential for late complications like pulmonary syndrome in survivors.]]></itunes:summary><itunes:duration>1007</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>14</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E13D: Cancer Biology - Hallmarks &amp; Telomeres</title><link>https://www.spreaker.com/episode/radbio-e13d-cancer-biology-hallmarks-telomeres--66162643</link><description><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that simplifies the science behind cancer treatment. This is Episode 13 Part D, Cancer Biology - Hallmarks &amp; Telomeres. In our previous cancer biology segments, we've explored the individual components: oncogenes, tumor suppressor genes, and the critical signaling pathways they control. Today, we're going to take a broader view, looking at the common capabilities that most, if not all, cancer cells acquire during their development. These are famously known as the "Hallmarks of Cancer," a framework proposed by Douglas Hanahan and Robert Weinberg. We'll also dive into one of the key mechanisms that allows cancer cells to divide indefinitely: telomere maintenance.]]></description><guid isPermaLink="false">e32e8a65-a312-46d9-8017-b633e98808e4</guid><pubDate>Tue, 20 May 2025 01:13:43 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66162643/400610533_44100_2_bf8bf29f5615f.mp3" length="15808195" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, the podcast that simplifies the science behind cancer treatment. This is Episode 13 Part D, Cancer Biology - Hallmarks &amp;amp; Telomeres. In our previous cancer biology segments, we've explored the individual...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that simplifies the science behind cancer treatment. This is Episode 13 Part D, Cancer Biology - Hallmarks &amp; Telomeres. In our previous cancer biology segments, we've explored the individual components: oncogenes, tumor suppressor genes, and the critical signaling pathways they control. Today, we're going to take a broader view, looking at the common capabilities that most, if not all, cancer cells acquire during their development. These are famously known as the "Hallmarks of Cancer," a framework proposed by Douglas Hanahan and Robert Weinberg. We'll also dive into one of the key mechanisms that allows cancer cells to divide indefinitely: telomere maintenance.]]></itunes:summary><itunes:duration>988</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E13C: Cancer Biology - Signaling: EGFR, Ras, PI3K, Myc, and NF-κB.</title><link>https://www.spreaker.com/episode/radbio-e13c-cancer-biology-signaling-egfr-ras-pi3k-myc-and-nf-kb--66162645</link><description><![CDATA[This is Episode 13 Part C, Cancer Biology - Signaling: EGFR, Ras, PI3K, Myc, and NF-κB.In our previous episodes on cancer biology, we've explored oncogenes – the cellular accelerators – and tumor suppressor genes – the cellular brakes. Today, we're going to connect these concepts by diving into the intricate communication networks within cells: the signaling pathways. These pathways dictate how cells respond to their environment, when to grow, when to divide, and when to die. We'll focus on some of the most important signaling pathways frequently dysregulated in cancer and highly relevant to radiation response, including the EGFR, Ras/MAPK, and PI3K/Akt pathways, and then look at the powerful downstream transcription factors Myc and NF-kappaB.]]></description><guid isPermaLink="false">ce304ff2-5460-4129-9352-1ea645dd3036</guid><pubDate>Tue, 20 May 2025 01:12:28 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66162645/400610457_44100_2_f5020574c1fc2.mp3" length="22503901" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 13 Part C, Cancer Biology - Signaling: EGFR, Ras, PI3K, Myc, and NF-κB.In our previous episodes on cancer biology, we've explored oncogenes – the cellular accelerators – and tumor suppressor genes – the cellular brakes. Today, we're...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 13 Part C, Cancer Biology - Signaling: EGFR, Ras, PI3K, Myc, and NF-κB.In our previous episodes on cancer biology, we've explored oncogenes – the cellular accelerators – and tumor suppressor genes – the cellular brakes. Today, we're going to connect these concepts by diving into the intricate communication networks within cells: the signaling pathways. These pathways dictate how cells respond to their environment, when to grow, when to divide, and when to die. We'll focus on some of the most important signaling pathways frequently dysregulated in cancer and highly relevant to radiation response, including the EGFR, Ras/MAPK, and PI3K/Akt pathways, and then look at the powerful downstream transcription factors Myc and NF-kappaB.]]></itunes:summary><itunes:duration>1407</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E13B: Repair Over Time: SLD, PLD &amp; Dose Rate TTS</title><link>https://www.spreaker.com/episode/radbio-e13b-repair-over-time-sld-pld-dose-rate-tts--66162644</link><description><![CDATA[Welcome back to Rad Onc Smart Review, the podcast dedicated to helping you master the core concepts of radiation oncology and radiobiology. This is Episode 13 Part B, Cancer Biology - Tumor Suppressor Genes .In our previous episode, we delved into the world of oncogenes, the "gas pedals" of the cell that, when stuck, can drive cancer. Today, we're turning our attention to the other side of the coin: Tumor Suppressor Genes, or TSGs. These are the "brakes" of the cell, crucial for keeping cell growth in check and maintaining the integrity of our genome. We'll explore what happens when these brakes fail, the classic "two-hit hypothesis" that explains their inactivation, and look at some key examples like RB1, TP53, and BRCA1/2.]]></description><guid isPermaLink="false">530ff3e5-2df8-41f9-b859-225113c56209</guid><pubDate>Tue, 20 May 2025 01:10:34 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66162644/400610378_44100_2_9fc1b46e9e091.mp3" length="23685054" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, the podcast dedicated to helping you master the core concepts of radiation oncology and radiobiology. This is Episode 13 Part B, Cancer Biology - Tumor Suppressor Genes .In our previous episode, we delved into the...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, the podcast dedicated to helping you master the core concepts of radiation oncology and radiobiology. This is Episode 13 Part B, Cancer Biology - Tumor Suppressor Genes .In our previous episode, we delved into the world of oncogenes, the "gas pedals" of the cell that, when stuck, can drive cancer. Today, we're turning our attention to the other side of the coin: Tumor Suppressor Genes, or TSGs. These are the "brakes" of the cell, crucial for keeping cell growth in check and maintaining the integrity of our genome. We'll explore what happens when these brakes fail, the classic "two-hit hypothesis" that explains their inactivation, and look at some key examples like RB1, TP53, and BRCA1/2.]]></itunes:summary><itunes:duration>1481</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E13A: Cancer Biology - Oncogenes</title><link>https://www.spreaker.com/episode/radbio-e13a-cancer-biology-oncogenes--66148974</link><description><![CDATA[Welcome back to Rad Onc Smart Review, the podcast dedicated to helping you master the core concepts of radiation oncology and radiobiology. This is Episode 13 Part A, Cancer Biology - Oncogenes.In our previous episodes, we've explored the intricacies of how radiation interacts with cells, the resulting damage and repair processes, and how cell populations, both normal and malignant, respond kinetically. Now, we begin a new chapter, diving into the fundamental molecular biology of cancer itself. Today, we'll focus on one of the key players in cancer development: oncogenes. We'll define what they are, explore the different ways normal cellular genes can be transformed into these cancer-promoting entities, and discuss some classic examples.]]></description><guid isPermaLink="false">32428c91-e779-467c-8fa5-850b136e59b3</guid><pubDate>Mon, 19 May 2025 10:09:19 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66148974/400557173_44100_2_5510721228f77.mp3" length="19645896" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, the podcast dedicated to helping you master the core concepts of radiation oncology and radiobiology. This is Episode 13 Part A, Cancer Biology - Oncogenes.In our previous episodes, we've explored the intricacies...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, the podcast dedicated to helping you master the core concepts of radiation oncology and radiobiology. This is Episode 13 Part A, Cancer Biology - Oncogenes.In our previous episodes, we've explored the intricacies of how radiation interacts with cells, the resulting damage and repair processes, and how cell populations, both normal and malignant, respond kinetically. Now, we begin a new chapter, diving into the fundamental molecular biology of cancer itself. Today, we'll focus on one of the key players in cancer development: oncogenes. We'll define what they are, explore the different ways normal cellular genes can be transformed into these cancer-promoting entities, and discuss some classic examples.]]></itunes:summary><itunes:duration>1228</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E12B:Tumor Kinetics - Tpot, GF &amp; Cell Loss</title><link>https://www.spreaker.com/episode/radbio-e12b-tumor-kinetics-tpot-gf-cell-loss--66148971</link><description><![CDATA[Welcome back to Rad Onc Smart Review, your go-to podcast for mastering the core concepts of radiation oncology and radiobiology. This is Episode 12 Part B, Tumor Kinetics - Tpot, GF &amp; Cell Loss. In our previous episode, P12a, we laid the groundwork by exploring the phases of the cell cycle, how radiosensitivity varies within them, and the techniques used to measure cell cycle parameters, like Percent Labeled Mitoses and Flow Cytometry. Today, we're going to build directly on that knowledge to understand the growth dynamics of tumors themselves. We'll define key kinetic parameters such as Labeling Index, Potential Doubling Time or Tpot, Growth Fraction, and the crucial Cell Loss Factor, and discuss how these factors, including accelerated repopulation, influence tumor growth and response to therapy.]]></description><guid isPermaLink="false">23b5180a-c64a-40b9-85fb-41f13ea1181f</guid><pubDate>Mon, 19 May 2025 10:07:39 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66148971/400557105_44100_2_7d79f79b8ad93.mp3" length="16137547" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, your go-to podcast for mastering the core concepts of radiation oncology and radiobiology. This is Episode 12 Part B, Tumor Kinetics - Tpot, GF &amp;amp; Cell Loss. In our previous episode, P12a, we laid the...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, your go-to podcast for mastering the core concepts of radiation oncology and radiobiology. This is Episode 12 Part B, Tumor Kinetics - Tpot, GF &amp; Cell Loss. In our previous episode, P12a, we laid the groundwork by exploring the phases of the cell cycle, how radiosensitivity varies within them, and the techniques used to measure cell cycle parameters, like Percent Labeled Mitoses and Flow Cytometry. Today, we're going to build directly on that knowledge to understand the growth dynamics of tumors themselves. We'll define key kinetic parameters such as Labeling Index, Potential Doubling Time or Tpot, Growth Fraction, and the crucial Cell Loss Factor, and discuss how these factors, including accelerated repopulation, influence tumor growth and response to therapy.]]></itunes:summary><itunes:duration>1009</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>12</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E12A: Cell Cycle Kinetics - Phases &amp; Measurement</title><link>https://www.spreaker.com/episode/radbio-e12a-cell-cycle-kinetics-phases-measurement--66148975</link><description><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that helps you master the core concepts of radiation oncology and radiobiology. This is Episode 12 Part A, Cell Cycle Kinetics - Phases &amp; Measurement. In our previous episodes, we've explored how tumors grow and respond to their microenvironment, including the crucial role of hypoxia and angiogenesis. Today, we're diving into the engine that drives cell growth and division: the cell cycle. We'll review its phases, discuss how radiosensitivity changes as cells progress through these phases, and explore key laboratory techniques used to measure and analyze cell cycle kinetics.]]></description><guid isPermaLink="false">6e7ca6da-0047-4dd3-b077-837c41da8aef</guid><pubDate>Mon, 19 May 2025 10:05:23 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66148975/400557000_44100_2_85fc90d594101.mp3" length="20523610" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, the podcast that helps you master the core concepts of radiation oncology and radiobiology. This is Episode 12 Part A, Cell Cycle Kinetics - Phases &amp;amp; Measurement. In our previous episodes, we've explored how...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that helps you master the core concepts of radiation oncology and radiobiology. This is Episode 12 Part A, Cell Cycle Kinetics - Phases &amp; Measurement. In our previous episodes, we've explored how tumors grow and respond to their microenvironment, including the crucial role of hypoxia and angiogenesis. Today, we're diving into the engine that drives cell growth and division: the cell cycle. We'll review its phases, discuss how radiosensitivity changes as cells progress through these phases, and explore key laboratory techniques used to measure and analyze cell cycle kinetics.]]></itunes:summary><itunes:duration>1283</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>12</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E11B: Tumor Microenvironment - Angiogenesis &amp; HIF-1</title><link>https://www.spreaker.com/episode/radbio-e11b-tumor-microenvironment-angiogenesis-hif-1--66148972</link><description><![CDATA[This is Episode 11 Part B, Tumor Microenvironment - Angiogenesis &amp; HIF-1. In our last episode, we explored the critical issue of tumor hypoxia and how reoxygenation plays a role during fractionated radiotherapy. Today, we're going to build on that by looking at how tumors try to get more oxygen by forming new blood vessels – a process called angiogenesis – and the master switch that controls this, a protein called HIF-1α.]]></description><guid isPermaLink="false">26faf75e-11b7-4a8f-a101-e2163427cf9f</guid><pubDate>Mon, 19 May 2025 10:03:00 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66148972/400556436_44100_2_614842689330f.mp3" length="17413994" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 11 Part B, Tumor Microenvironment - Angiogenesis &amp;amp; HIF-1. In our last episode, we explored the critical issue of tumor hypoxia and how reoxygenation plays a role during fractionated radiotherapy. Today, we're going to build on that...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 11 Part B, Tumor Microenvironment - Angiogenesis &amp; HIF-1. In our last episode, we explored the critical issue of tumor hypoxia and how reoxygenation plays a role during fractionated radiotherapy. Today, we're going to build on that by looking at how tumors try to get more oxygen by forming new blood vessels – a process called angiogenesis – and the master switch that controls this, a protein called HIF-1α.]]></itunes:summary><itunes:duration>1089</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>11</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E11A: Tumor Microenvironment - Hypoxia &amp; Reoxygenation</title><link>https://www.spreaker.com/episode/radbio-e11a-tumor-microenvironment-hypoxia-reoxygenation--66148976</link><description><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that helps you master the core concepts of radiation oncology and radiobiology. This is Episode 11 part A, Tumor Microenvironment - Hypoxia &amp; Reoxygenation. Today, we're diving deep into the tumor microenvironment, specifically focusing on why some parts of tumors don't get enough oxygen, how this hypoxia affects radiation treatment, and the fascinating reoxygenation process that can occur during fractionated radiotherapy.]]></description><guid isPermaLink="false">307e0744-0578-49b5-81e5-58a9c9f47248</guid><pubDate>Mon, 19 May 2025 09:41:44 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66148976/400556055_44100_2_f3a3ea461a072.mp3" length="22338807" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, the podcast that helps you master the core concepts of radiation oncology and radiobiology. This is Episode 11 part A, Tumor Microenvironment - Hypoxia &amp;amp; Reoxygenation. Today, we're diving deep into the tumor...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that helps you master the core concepts of radiation oncology and radiobiology. This is Episode 11 part A, Tumor Microenvironment - Hypoxia &amp; Reoxygenation. Today, we're diving deep into the tumor microenvironment, specifically focusing on why some parts of tumors don't get enough oxygen, how this hypoxia affects radiation treatment, and the fascinating reoxygenation process that can occur during fractionated radiotherapy.]]></itunes:summary><itunes:duration>1397</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>11</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E10: Tumor Assays: Growth Delay &amp; TCD50</title><link>https://www.spreaker.com/episode/radbio-e10-tumor-assays-growth-delay-tcd50--66141924</link><description><![CDATA[Welcome back to Rad Onc Smart Review.This is Episode 10, Tumor Assays: Growth Delay &amp; TCD50.In our previous episodes, we delved into the cellular responses to radiation, looking at survival curves and models like the LQ model, often derived from in vitro cell culture experiments. But how do tumors respond within the complex environment of a living organism? Today, we're moving from the petri dish to in vivo models, exploring the key experimental assays used to measure how solid tumors respond to radiation treatment, including methods that assess tumor control, cell survival, and growth perturbations.]]></description><guid isPermaLink="false">ea25f529-049d-48a5-bd42-32c7578a403a</guid><pubDate>Sun, 18 May 2025 19:14:47 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66141924/400522446_44100_2_8e0fd5d3c31c4.mp3" length="19126791" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review.This is Episode 10, Tumor Assays: Growth Delay &amp;amp; TCD50.In our previous episodes, we delved into the cellular responses to radiation, looking at survival curves and models like the LQ model, often derived from...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review.This is Episode 10, Tumor Assays: Growth Delay &amp; TCD50.In our previous episodes, we delved into the cellular responses to radiation, looking at survival curves and models like the LQ model, often derived from in vitro cell culture experiments. But how do tumors respond within the complex environment of a living organism? Today, we're moving from the petri dish to in vivo models, exploring the key experimental assays used to measure how solid tumors respond to radiation treatment, including methods that assess tumor control, cell survival, and growth perturbations.]]></itunes:summary><itunes:duration>1196</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>10</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E9: Repair Over Time: SLD, PLD &amp; Dose Rate TTS</title><link>https://www.spreaker.com/episode/radbio-e9-repair-over-time-sld-pld-dose-rate-tts--66090208</link><description><![CDATA[Welcome back to Rad Onc Smart Review. This is Episode 9, Repair, SLD, PLD &amp; Dose Rate Effects. Today, we're diving deep into how cells respond to radiation damage, focusing on the crucial concepts of sublethal and potentially lethal damage repair, and how the rate at which radiation is delivered can dramatically alter these biological outcomes.]]></description><guid isPermaLink="false">65175135-6c1a-4a68-ab69-124caebb0ec8</guid><pubDate>Wed, 14 May 2025 19:16:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66090208/400289926_44100_2_b734055d3d7e2.mp3" length="17566967" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review. This is Episode 9, Repair, SLD, PLD &amp;amp; Dose Rate Effects. Today, we're diving deep into how cells respond to radiation damage, focusing on the crucial concepts of sublethal and potentially lethal damage repair,...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review. This is Episode 9, Repair, SLD, PLD &amp; Dose Rate Effects. Today, we're diving deep into how cells respond to radiation damage, focusing on the crucial concepts of sublethal and potentially lethal damage repair, and how the rate at which radiation is delivered can dramatically alter these biological outcomes.]]></itunes:summary><itunes:duration>1098</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>9</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E8: The Oxygen Effect and Oxygen Enhancement Ratio</title><link>https://www.spreaker.com/episode/radbio-e8-the-oxygen-effect-and-oxygen-enhancement-ratio--66080696</link><description><![CDATA[This is Episode 8, The Oxygen Effect &amp; OER.In our last episode, we explored how Linear Energy Transfer (LET) influences the Relative Biological Effectiveness (RBE) of different radiation types, explaining why equal absorbed doses don't always lead to equal biological damage. Today, we delve into another crucial factor that dramatically modifies radiation response, particularly for the low-LET radiation commonly used in therapy: molecular oxygen. We'll explain the mechanism behind oxygen's radiosensitizing effect and define the Oxygen Enhancement Ratio, or OER.]]></description><guid isPermaLink="false">b403c8f8-90c4-43fe-9195-7620a058c87d</guid><pubDate>Wed, 14 May 2025 04:03:57 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66080696/400239994_44100_2_ee86b749bd956.mp3" length="14977292" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 8, The Oxygen Effect &amp;amp; OER.In our last episode, we explored how Linear Energy Transfer (LET) influences the Relative Biological Effectiveness (RBE) of different radiation types, explaining why equal absorbed doses don't always lead...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 8, The Oxygen Effect &amp; OER.In our last episode, we explored how Linear Energy Transfer (LET) influences the Relative Biological Effectiveness (RBE) of different radiation types, explaining why equal absorbed doses don't always lead to equal biological damage. Today, we delve into another crucial factor that dramatically modifies radiation response, particularly for the low-LET radiation commonly used in therapy: molecular oxygen. We'll explain the mechanism behind oxygen's radiosensitizing effect and define the Oxygen Enhancement Ratio, or OER.]]></itunes:summary><itunes:duration>936</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>8</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E7: LET's Talk R B E.</title><link>https://www.spreaker.com/episode/radbio-e7-let-s-talk-r-b-e--66022410</link><description><![CDATA[This is Episode 7, LET's Talk RBE.In our last episode, we saw how mathematical models like the Linear-Quadratic model describe cell survival curves. But a key point emerged: equal doses of different types of radiation don't necessarily produce equal biological effects. Today, we'll quantify these differences by defining two fundamental concepts: Linear Energy Transfer, or LET, and Relative Biological Effectiveness, or RBE, and exploring the crucial relationship between them.]]></description><guid isPermaLink="false">7bbefea7-8160-44a4-86c6-5198cf042360</guid><pubDate>Fri, 09 May 2025 20:26:46 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/66022410/399954750_44100_2_029a16265c4a7.mp3" length="20335947" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 7, LET's Talk RBE.In our last episode, we saw how mathematical models like the Linear-Quadratic model describe cell survival curves. But a key point emerged: equal doses of different types of radiation don't necessarily produce equal...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 7, LET's Talk RBE.In our last episode, we saw how mathematical models like the Linear-Quadratic model describe cell survival curves. But a key point emerged: equal doses of different types of radiation don't necessarily produce equal biological effects. Today, we'll quantify these differences by defining two fundamental concepts: Linear Energy Transfer, or LET, and Relative Biological Effectiveness, or RBE, and exploring the crucial relationship between them.]]></itunes:summary><itunes:duration>1271</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>7</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E6: Modeling Survival: Target Theory and L Q.</title><link>https://www.spreaker.com/episode/radbio-e6-modeling-survival-target-theory-and-l-q--65982138</link><description><![CDATA[This is Episode 6, Modeling Survival: Target Theory and L Q.In our last episode, we looked at how radiobiologists actually measure cell survival using clonogenic assays. These experiments generate dose-response data, typically plotted as cell survival curves. Today, we'll explore the mathematical models developed to describe and understand the characteristic shapes of these survival curves, focusing on the historical Target Theory and the current standard, the Linear-Quadratic model.]]></description><guid isPermaLink="false">ad7c70e3-f9e4-4b07-a868-248d5b0c4383</guid><pubDate>Wed, 07 May 2025 18:55:22 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65982138/399810771_44100_2_e25dc1fb1872a.mp3" length="19751222" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 6, Modeling Survival: Target Theory and L Q.In our last episode, we looked at how radiobiologists actually measure cell survival using clonogenic assays. These experiments generate dose-response data, typically plotted as cell survival...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 6, Modeling Survival: Target Theory and L Q.In our last episode, we looked at how radiobiologists actually measure cell survival using clonogenic assays. These experiments generate dose-response data, typically plotted as cell survival curves. Today, we'll explore the mathematical models developed to describe and understand the characteristic shapes of these survival curves, focusing on the historical Target Theory and the current standard, the Linear-Quadratic model.]]></itunes:summary><itunes:duration>1235</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>6</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E5: Measuring Survival: Clonogenic Assays.</title><link>https://www.spreaker.com/episode/radbio-e5-measuring-survival-clonogenic-assays--65982129</link><description><![CDATA[This is Episode 5, Measuring Survival: Clonogenic Assays.In our last episode, we explored the different ways cells can die after radiation – apoptosis, necrosis, mitotic catastrophe, and others. But in radiation oncology, the ultimate goal isn't just causing immediate cell death, it's preventing tumor cells from dividing and regrowing. Today, we'll focus on the "gold standard" methods used in radiobiology to measure this loss of reproductive capability, both in the lab dish and within living organisms.]]></description><guid isPermaLink="false">47a4ab35-55d0-4551-9123-e96608182676</guid><pubDate>Wed, 07 May 2025 18:47:44 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65982129/399810331_44100_2_5ddc8c9a0eeb.mp3" length="17986180" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 5, Measuring Survival: Clonogenic Assays.In our last episode, we explored the different ways cells can die after radiation – apoptosis, necrosis, mitotic catastrophe, and others. But in radiation oncology, the ultimate goal isn't just...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 5, Measuring Survival: Clonogenic Assays.In our last episode, we explored the different ways cells can die after radiation – apoptosis, necrosis, mitotic catastrophe, and others. But in radiation oncology, the ultimate goal isn't just causing immediate cell death, it's preventing tumor cells from dividing and regrowing. Today, we'll focus on the "gold standard" methods used in radiobiology to measure this loss of reproductive capability, both in the lab dish and within living organisms.]]></itunes:summary><itunes:duration>1125</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/19baf85b6ae5fe8104758002deceb69b.jpg"/><itunes:season>2</itunes:season><itunes:episode>5</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E4: DNA Repair: Mechanisms of Cell Death &amp; Response</title><link>https://www.spreaker.com/episode/radbio-e4-dna-repair-mechanisms-of-cell-death-response--65980500</link><description><![CDATA[Welcome back to Rad Onc Smart Review. This is Episode 4, Mechanisms of Cell Death &amp; Response.Last time, we explored how radiation can cause major structural damage to chromosomes. Today, we're diving into the consequences of that damage, looking at the diverse ways cells respond when faced with radiation injury – focusing on the distinct pathways leading to cell death or dysfunction, including apoptosis, necrosis, mitotic catastrophe, autophagy, and senescence. Knowing how to differentiate these is key for understanding treatment response.]]></description><guid isPermaLink="false">4b3bb4d7-99ea-43b1-a9a0-03b6e44eb16a</guid><pubDate>Wed, 07 May 2025 18:21:55 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65980500/399808293_44100_2_2a6165cd83c11.mp3" length="19774210" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review. This is Episode 4, Mechanisms of Cell Death &amp;amp; Response.Last time, we explored how radiation can cause major structural damage to chromosomes. Today, we're diving into the consequences of that damage, looking...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review. This is Episode 4, Mechanisms of Cell Death &amp; Response.Last time, we explored how radiation can cause major structural damage to chromosomes. Today, we're diving into the consequences of that damage, looking at the diverse ways cells respond when faced with radiation injury – focusing on the distinct pathways leading to cell death or dysfunction, including apoptosis, necrosis, mitotic catastrophe, autophagy, and senescence. Knowing how to differentiate these is key for understanding treatment response.]]></itunes:summary><itunes:duration>1236</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/29eaffec47795702d337c1fca6632df9.jpg"/><itunes:season>2</itunes:season><itunes:episode>4</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E3: DNA Repair: Chromosome Damage and Repair Syndromes</title><link>https://www.spreaker.com/episode/radbio-e3-dna-repair-chromosome-damage-and-repair-syndromes--65801633</link><description><![CDATA[In our last episodes, we drilled down into how cells repair specific DNA lesions, like base damage, single-strand breaks, and those critical double-strand breaks via NHEJ and HR. Today, we're zooming out to look at the bigger picture: what happens when DNA breaks lead to large-scale damage visible at the chromosome level? We'll cover different types of chromosome aberrations caused by radiation, classifying them as lethal or potentially cancer-promoting, and link these concepts to human genetic syndromes caused by defects in DNA repair.]]></description><guid isPermaLink="false">32a89201-3590-4a66-9632-c5c6d7b391a2</guid><pubDate>Wed, 30 Apr 2025 03:32:32 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65801633/399324238_44100_2_58ae5b8a907a2.mp3" length="26604081" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our last episodes, we drilled down into how cells repair specific DNA lesions, like base damage, single-strand breaks, and those critical double-strand breaks via NHEJ and HR. Today, we're zooming out to look at the bigger picture: what happens...</itunes:subtitle><itunes:summary><![CDATA[In our last episodes, we drilled down into how cells repair specific DNA lesions, like base damage, single-strand breaks, and those critical double-strand breaks via NHEJ and HR. Today, we're zooming out to look at the bigger picture: what happens when DNA breaks lead to large-scale damage visible at the chromosome level? We'll cover different types of chromosome aberrations caused by radiation, classifying them as lethal or potentially cancer-promoting, and link these concepts to human genetic syndromes caused by defects in DNA repair.]]></itunes:summary><itunes:duration>1663</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/6e787c748e0ed75db92c8ff1c623b121.jpg"/><itunes:season>2</itunes:season><itunes:episode>3</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E2c: Homologous Recombination</title><link>https://www.spreaker.com/episode/radbio-e2c-homologous-recombination--65801100</link><description><![CDATA[In our previous episode, we discussed how cells handle single strand breaks and how they perform a quick but potentially error filled patch up of double strand breaks using Non-Homologous End Joining, or NHE J. Today, we're diving into the cell's high fidelity repair system for double strand breaks: Homologous Recombination, or HR. We'll explore how it works, why it's so accurate, and highlight the crucial roles played by proteins like BRCA 1 and BRCA 2.]]></description><guid isPermaLink="false">41f650e6-0c9a-44fc-9009-910606bd03c4</guid><pubDate>Wed, 30 Apr 2025 02:36:13 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65801100/399322113_44100_2_d0ab9f2388956.mp3" length="18227761" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>In our previous episode, we discussed how cells handle single strand breaks and how they perform a quick but potentially error filled patch up of double strand breaks using Non-Homologous End Joining, or NHE J. Today, we're diving into the cell's high...</itunes:subtitle><itunes:summary><![CDATA[In our previous episode, we discussed how cells handle single strand breaks and how they perform a quick but potentially error filled patch up of double strand breaks using Non-Homologous End Joining, or NHE J. Today, we're diving into the cell's high fidelity repair system for double strand breaks: Homologous Recombination, or HR. We'll explore how it works, why it's so accurate, and highlight the crucial roles played by proteins like BRCA 1 and BRCA 2.]]></itunes:summary><itunes:duration>1140</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>2</itunes:season><itunes:episode>2</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode 17 D: Lungs, Seeds, and Safety Shields</title><link>https://www.spreaker.com/episode/physics-episode-17-d-lungs-seeds-and-safety-shields--65798874</link><description><![CDATA[This is our final episode focused purely on calculations! We've journeyed from basic decay to complex Monitor Unit calculations. Today, we hit the advanced scenarios: What happens when the beam hits lung or bone? How do we compare radically different fractionation schemes biologically? How does modern brachytherapy dosimetry really work with TG 43? And finally, the essential math for keeping everyone safe from radiation. Today, we’re calculating radiological path length, BED and EQD 2, applying the TG 43 framework with Air Kerma Strength, and ensuring our shielding calculations meet regulatory limits.]]></description><guid isPermaLink="false">e0bffd53-dc68-43ec-8465-d08db7f02f01</guid><pubDate>Tue, 29 Apr 2025 22:02:59 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65798874/399311426_44100_2_12f2ba51fa457.mp3" length="22383947" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is our final episode focused purely on calculations! We've journeyed from basic decay to complex Monitor Unit calculations. Today, we hit the advanced scenarios: What happens when the beam hits lung or bone? How do we compare radically different...</itunes:subtitle><itunes:summary><![CDATA[This is our final episode focused purely on calculations! We've journeyed from basic decay to complex Monitor Unit calculations. Today, we hit the advanced scenarios: What happens when the beam hits lung or bone? How do we compare radically different fractionation schemes biologically? How does modern brachytherapy dosimetry really work with TG 43? And finally, the essential math for keeping everyone safe from radiation. Today, we’re calculating radiological path length, BED and EQD 2, applying the TG 43 framework with Air Kerma Strength, and ensuring our shielding calculations meet regulatory limits.]]></itunes:summary><itunes:duration>1399</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P17c: Dose Divers and Electron Escapades</title><link>https://www.spreaker.com/episode/physics-episode-p17c-dose-divers-and-electron-escapades--65778038</link><description><![CDATA[Welcome back to Radiation Oncology Smart Review – Calculation Toolkit Episode 17C: Dose Divers and Electron Escapades. Last time, we calibrated our detectors and nailed Monitor Unit calculations for standard setups. Now, we follow the dose after it leaves the machine head. Today, we'll master transferring dose between different depths using Percent Depth Doses and Tissue Maximum Ratios, untangle the geometric puzzles of skin gaps for field matching, learn the simple scaling rules for field sizes, calculate equivalent squares, and dip our toes into the unique world of electron beam Monitor Unit calculations.]]></description><guid isPermaLink="false">66711eef-3994-4aad-aad6-183ef3249924</guid><pubDate>Mon, 28 Apr 2025 08:20:01 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65778038/399204385_44100_2_5a0c6823ea91.mp3" length="15579153" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Radiation Oncology Smart Review – Calculation Toolkit Episode 17C: Dose Divers and Electron Escapades. Last time, we calibrated our detectors and nailed Monitor Unit calculations for standard setups. Now, we follow the dose after it...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Radiation Oncology Smart Review – Calculation Toolkit Episode 17C: Dose Divers and Electron Escapades. Last time, we calibrated our detectors and nailed Monitor Unit calculations for standard setups. Now, we follow the dose after it leaves the machine head. Today, we'll master transferring dose between different depths using Percent Depth Doses and Tissue Maximum Ratios, untangle the geometric puzzles of skin gaps for field matching, learn the simple scaling rules for field sizes, calculate equivalent squares, and dip our toes into the unique world of electron beam Monitor Unit calculations.]]></itunes:summary><itunes:duration>974</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P17B: Dosimetry Detectives and Chamber Charades</title><link>https://www.spreaker.com/episode/physics-episode-p17b-dosimetry-detectives-and-chamber-charades--65778039</link><description><![CDATA[Welcome back to Radiation Oncology Smart Review – Episode 17 part B: Dosimetry Detectives and Chamber Charades. Last time, we tackled the ticking clocks of decay and permanent implants. Today, we put on our detective hats to investigate how we actually measure radiation and make sure the right dose goes to the right place. We’ll decode the secrets of ion chambers and their sneaky temperature-pressure dependence, master the Monitor Unit, or M U, calculations for both S A D and S S D setups – the absolute bedrock of clinical physics – figure out how dose changes with depth using P D Ds and T M Rs, and learn how linacs play geometric tricks with field sizes.]]></description><guid isPermaLink="false">ed2543de-2abd-44a9-afd5-2786caa95c57</guid><pubDate>Mon, 28 Apr 2025 08:10:44 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65778039/399204062_44100_2_ed0eb5a1702cf.mp3" length="14885759" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Radiation Oncology Smart Review – Episode 17 part B: Dosimetry Detectives and Chamber Charades. Last time, we tackled the ticking clocks of decay and permanent implants. Today, we put on our detective hats to investigate how we...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Radiation Oncology Smart Review – Episode 17 part B: Dosimetry Detectives and Chamber Charades. Last time, we tackled the ticking clocks of decay and permanent implants. Today, we put on our detective hats to investigate how we actually measure radiation and make sure the right dose goes to the right place. We’ll decode the secrets of ion chambers and their sneaky temperature-pressure dependence, master the Monitor Unit, or M U, calculations for both S A D and S S D setups – the absolute bedrock of clinical physics – figure out how dose changes with depth using P D Ds and T M Rs, and learn how linacs play geometric tricks with field sizes.]]></itunes:summary><itunes:duration>931</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P17a: Calculations 1: Half-Lives and Seed Sleuths</title><link>https://www.spreaker.com/episode/physics-episode-p17a-calculations-1-half-lives-and-seed-sleuths--65778041</link><description><![CDATA[Welcome back to Radiation Oncology Smart Review – the targeted prep for your radiation oncology boards! I’m your guide, diving deep into the calculations that matter. This is Episode 17a of our Calculation Toolkit series, titled Radiation Oncology Calculations 1: Half-Lives and Seed Sleuths. Today we’ll master three bread-and-butter RAPHEX problem families: first, radioactive decay and time-activity puzzles, second, effective half-life mash-ups, and third, permanent implant total-dose questions. By the end you’ll know why lambda keeps physicists up at night, how to find the Goldilocks half-life combining body and physics, and how one sleepy iodine one twenty-five seed still manages to deliver its full punch over months.]]></description><guid isPermaLink="false">16c56509-64e4-416f-a8c0-b52103563fd1</guid><pubDate>Mon, 28 Apr 2025 08:01:43 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65778041/399203761_44100_2_92e6c90639585.mp3" length="14884505" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Radiation Oncology Smart Review – the targeted prep for your radiation oncology boards! I’m your guide, diving deep into the calculations that matter. This is Episode 17a of our Calculation Toolkit series, titled Radiation Oncology...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Radiation Oncology Smart Review – the targeted prep for your radiation oncology boards! I’m your guide, diving deep into the calculations that matter. This is Episode 17a of our Calculation Toolkit series, titled Radiation Oncology Calculations 1: Half-Lives and Seed Sleuths. Today we’ll master three bread-and-butter RAPHEX problem families: first, radioactive decay and time-activity puzzles, second, effective half-life mash-ups, and third, permanent implant total-dose questions. By the end you’ll know why lambda keeps physicists up at night, how to find the Goldilocks half-life combining body and physics, and how one sleepy iodine one twenty-five seed still manages to deliver its full punch over months.]]></itunes:summary><itunes:duration>931</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>17</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E2b: DNA Repair: Single-Strand Breaks &amp; NHEJ.</title><link>https://www.spreaker.com/episode/radbio-e2b-dna-repair-single-strand-breaks-nhej--65758244</link><description><![CDATA[This is Episode 2b, DNA Repair: Single-Strand Breaks&amp; NHEJ.Last time, we delved into Base Excision Repair andNucleotide Excision Repair, the cell's tools for fixing damaged bases and bulkylesions. But ionizing radiation does more than just damage bases – itfrequently breaks the sugar-phosphate backbone of DNA. Today, we'll explore howcells handle single-strand breaks and introduce the first major pathway forrepairing the most critical radiation-induced lesion: the double-strand break,specifically focusing on the fast but potentially risky pathway called Non-HomologousEnd Joining, or NHEJ.]]></description><guid isPermaLink="false">e974dc7e-a962-453f-99e3-80b6ca979977</guid><pubDate>Sun, 27 Apr 2025 03:57:42 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65758244/399146822_44100_2_dd38a4b2d09db.mp3" length="24744162" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>This is Episode 2b, DNA Repair: Single-Strand Breaks&amp;amp; NHEJ.Last time, we delved into Base Excision Repair andNucleotide Excision Repair, the cell's tools for fixing damaged bases and bulkylesions. But ionizing radiation does more than just damage...</itunes:subtitle><itunes:summary><![CDATA[This is Episode 2b, DNA Repair: Single-Strand Breaks&amp; NHEJ.Last time, we delved into Base Excision Repair andNucleotide Excision Repair, the cell's tools for fixing damaged bases and bulkylesions. But ionizing radiation does more than just damage bases – itfrequently breaks the sugar-phosphate backbone of DNA. Today, we'll explore howcells handle single-strand breaks and introduce the first major pathway forrepairing the most critical radiation-induced lesion: the double-strand break,specifically focusing on the fast but potentially risky pathway called Non-HomologousEnd Joining, or NHEJ.]]></itunes:summary><itunes:duration>1547</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/6e787c748e0ed75db92c8ff1c623b121.jpg"/><itunes:season>2</itunes:season><itunes:episode>2</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E2a: DNA Repair: Base &amp; Nucleotide Excision</title><link>https://www.spreaker.com/episode/radbio-e2a-dna-repair-base-nucleotide-excision--65733527</link><description><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that helps you master radiation oncology concepts for your boards and beyond.This is Episode 2a, DNA Repair: Base &amp; Nucleotide Excision.In our last episode, we saw how radiation causes a spectrum of DNA damage. Today, we'll start exploring how the cell fights back, focusing on two crucial repair pathways: Base Excision Repair for smaller lesions and Nucleotide Excision Repair for bulkier damage.]]></description><guid isPermaLink="false">bb26eabb-7b90-4985-94d5-465e11f33901</guid><pubDate>Fri, 25 Apr 2025 23:35:59 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65733527/399102659_44100_2_fc919a599e3a2.mp3" length="20611382" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, the podcast that helps you master radiation oncology concepts for your boards and beyond.This is Episode 2a, DNA Repair: Base &amp;amp; Nucleotide Excision.In our last episode, we saw how radiation causes a spectrum...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that helps you master radiation oncology concepts for your boards and beyond.This is Episode 2a, DNA Repair: Base &amp; Nucleotide Excision.In our last episode, we saw how radiation causes a spectrum of DNA damage. Today, we'll start exploring how the cell fights back, focusing on two crucial repair pathways: Base Excision Repair for smaller lesions and Nucleotide Excision Repair for bulkier damage.]]></itunes:summary><itunes:duration>1289</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/29eaffec47795702d337c1fca6632df9.jpg"/><itunes:season>2</itunes:season><itunes:episode>2</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>RadBio E1: Radiation Interaction &amp; Damage Basics</title><link>https://www.spreaker.com/episode/radbio-e1-radiation-interaction-damage-basics--65731923</link><description><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that helps you master radiation oncology concepts for your boards and beyond.This is Episode 1, Radiation Interaction &amp; Damage Basics.Today, we’ll explore how ionizing radiation initially interacts with cells, focusing on direct versus indirect effects, and the different types of damage caused to our primary target, DNA.]]></description><guid isPermaLink="false">fa8bbcb3-57cd-4fc7-a040-a6828944b9da</guid><pubDate>Fri, 25 Apr 2025 22:18:56 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65731923/ac18f616_47a3_a11a_61b6_3808eef24862.mp3" length="44325869" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to Rad Onc Smart Review, the podcast that helps you master radiation oncology concepts for your boards and beyond.This is Episode 1, Radiation Interaction &amp;amp; Damage Basics.Today, we’ll explore how ionizing radiation initially interacts...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to Rad Onc Smart Review, the podcast that helps you master radiation oncology concepts for your boards and beyond.This is Episode 1, Radiation Interaction &amp; Damage Basics.Today, we’ll explore how ionizing radiation initially interacts with cells, focusing on direct versus indirect effects, and the different types of damage caused to our primary target, DNA.]]></itunes:summary><itunes:duration>1847</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/29eaffec47795702d337c1fca6632df9.jpg"/><itunes:season>2</itunes:season><itunes:episode>1</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P16c: PET &amp; Ultrasound Physics for RadOnc</title><link>https://www.spreaker.com/episode/physics-episode-p16c-pet-ultrasound-physics-for-radonc--65575404</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series for our concluding episode! In P16b, we explored the crucial planning modalities of CT and MRI. Today, in Episode P16c: PET &amp; Ultrasound Physics for RadOnc, we round out our imaging tour by looking at two other important technologies: Positron Emission Tomography (PET), which gives us insights into metabolic function, and Ultrasound (US), often used for real-time guidance and visualizing certain structures.]]></description><guid isPermaLink="false">e51b07d6-d076-4bba-8c19-216623d7dd03</guid><pubDate>Sun, 06 Apr 2025 21:34:22 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575404/398209510_44100_2_ecc2ecc7adf04.mp3" length="25884355" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series for our concluding episode! In P16b, we explored the crucial planning modalities of CT and MRI. Today, in Episode P16c: PET &amp;amp; Ultrasound Physics for RadOnc, we round out our imaging tour by...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series for our concluding episode! In P16b, we explored the crucial planning modalities of CT and MRI. Today, in Episode P16c: PET &amp; Ultrasound Physics for RadOnc, we round out our imaging tour by looking at two other important technologies: Positron Emission Tomography (PET), which gives us insights into metabolic function, and Ultrasound (US), often used for real-time guidance and visualizing certain structures.]]></itunes:summary><itunes:duration>1618</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/740592ba69a5224dbb811976ab759996.jpg"/><itunes:season>1</itunes:season><itunes:episode>16</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P16b: CT &amp; MRI Physics for RadOnc</title><link>https://www.spreaker.com/episode/physics-episode-p16b-ct-mri-physics-for-radonc--65575430</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P16a, we covered the crucial principles of radiation protection and the regulations governing our field. Now, in Episode P16b: CT &amp; MRI Physics for RadOnc, we dive into the physics behind the two imaging modalities most fundamental to treatment planning: Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). How do they create the detailed anatomical images we rely on every day?]]></description><guid isPermaLink="false">525ea3e3-e395-49c8-8a85-c334c7a88846</guid><pubDate>Sun, 06 Apr 2025 20:34:21 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575430/397928116_44100_2_7e0574d3a97e7.mp3" length="20436675" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P16a, we covered the crucial principles of radiation protection and the regulations governing our field. Now, in Episode P16b: CT &amp;amp; MRI Physics for RadOnc, we dive into the physics behind...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P16a, we covered the crucial principles of radiation protection and the regulations governing our field. Now, in Episode P16b: CT &amp; MRI Physics for RadOnc, we dive into the physics behind the two imaging modalities most fundamental to treatment planning: Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). How do they create the detailed anatomical images we rely on every day?]]></itunes:summary><itunes:duration>1278</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>16</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P16a: Radiation Protection &amp; Regulations</title><link>https://www.spreaker.com/episode/physics-episode-p16a-radiation-protection-regulations--65575461</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've explored how radiation is produced, how it interacts, how we measure it, plan treatments, and ensure quality. Now, we circle back to a fundamental responsibility: radiation safety. In Episode P16a: Radiation Protection &amp; Regulations, we'll review the types of radiation effects, the quantities used to measure risk (Dose Equivalent, Effective Dose), the ALARA principle, the critical regulatory dose limits for workers and the public, and touch upon managing dose from internal radioactivity.]]></description><guid isPermaLink="false">bf626632-1de7-438d-8c12-1a53ad0d742b</guid><pubDate>Sun, 06 Apr 2025 20:33:10 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575461/397927489_44100_2_cd5d6bf56e68b.mp3" length="25246549" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! We've explored how radiation is produced, how it interacts, how we measure it, plan treatments, and ensure quality. Now, we circle back to a fundamental responsibility: radiation safety. In...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've explored how radiation is produced, how it interacts, how we measure it, plan treatments, and ensure quality. Now, we circle back to a fundamental responsibility: radiation safety. In Episode P16a: Radiation Protection &amp; Regulations, we'll review the types of radiation effects, the quantities used to measure risk (Dose Equivalent, Effective Dose), the ALARA principle, the critical regulatory dose limits for workers and the public, and touch upon managing dose from internal radioactivity.]]></itunes:summary><itunes:duration>1578</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>16</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P15c: Brachytherapy QA, Safety &amp; Regulations</title><link>https://www.spreaker.com/episode/physics-episode-p15c-brachytherapy-qa-safety-regulations--65575431</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P15a, we covered brachytherapy sources and TG-43 dose calculations. In P15b, we looked at clinical applications and planning systems. Now, in our final brachytherapy episode, P15c: Brachytherapy QA, Safety &amp; Regulations, we focus on arguably the most critical aspect: ensuring these procedures are performed safely and accurately, protecting both patients and staff, and complying with strict regulatory requirements.]]></description><guid isPermaLink="false">d5d2970d-15d7-467b-976e-c5a48be89cf7</guid><pubDate>Sun, 06 Apr 2025 20:23:31 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575431/397927422_44100_2_eb10d680c371b.mp3" length="18833801" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P15a, we covered brachytherapy sources and TG-43 dose calculations. In P15b, we looked at clinical applications and planning systems. Now, in our final brachytherapy episode, P15c:...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P15a, we covered brachytherapy sources and TG-43 dose calculations. In P15b, we looked at clinical applications and planning systems. Now, in our final brachytherapy episode, P15c: Brachytherapy QA, Safety &amp; Regulations, we focus on arguably the most critical aspect: ensuring these procedures are performed safely and accurately, protecting both patients and staff, and complying with strict regulatory requirements.]]></itunes:summary><itunes:duration>1178</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P15b: Brachytherapy Applications, Systems &amp; Planning Concepts</title><link>https://www.spreaker.com/episode/physics-episode-p15b-brachytherapy-applications-systems-planning-concepts--65575444</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P15a, we laid the groundwork for brachytherapy, focusing on the radioactive sources, how their strength is quantified using Air Kerma Strength (SK), and the details of the TG-43 dose calculation formalism. Now, in Episode P15b: Brachytherapy Applications, Systems &amp; Planning Concepts, we'll explore how these sources are actually used clinically – looking at intracavitary vs interstitial techniques, historical planning systems, and specific dose points like ICRU 38's Points A and B.]]></description><guid isPermaLink="false">ee16ae09-06a6-4de6-8f6d-d51a793b94bc</guid><pubDate>Sun, 06 Apr 2025 20:22:51 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575444/397927394_44100_2_d3b7921b13007.mp3" length="25890206" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P15a, we laid the groundwork for brachytherapy, focusing on the radioactive sources, how their strength is quantified using Air Kerma Strength (SK), and the details of the TG-43 dose...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P15a, we laid the groundwork for brachytherapy, focusing on the radioactive sources, how their strength is quantified using Air Kerma Strength (SK), and the details of the TG-43 dose calculation formalism. Now, in Episode P15b: Brachytherapy Applications, Systems &amp; Planning Concepts, we'll explore how these sources are actually used clinically – looking at intracavitary vs interstitial techniques, historical planning systems, and specific dose points like ICRU 38's Points A and B.]]></itunes:summary><itunes:duration>1619</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P15a: Brachytherapy Physics - Sources, Strength &amp; Dose Calculation</title><link>https://www.spreaker.com/episode/physics-episode-p15a-brachytherapy-physics-sources-strength-dose-calculation--65575408</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've thoroughly covered external beam therapy. Now, we're shifting gears dramatically to explore treatments where the radiation source is placed inside or very close to the target. In Episode P15a: Brachytherapy Physics - Sources, Strength &amp; Dose Calculation, we'll introduce the common radioactive isotopes used, discuss how their strength is properly quantified, and meticulously break down the fundamental TG-43 formalism used for calculating dose around these sources.]]></description><guid isPermaLink="false">6eb165be-5119-4e34-8263-396fd8c32734</guid><pubDate>Sun, 06 Apr 2025 20:21:49 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575408/397927344_44100_2_d451fe7c100c5.mp3" length="25035480" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! We've thoroughly covered external beam therapy. Now, we're shifting gears dramatically to explore treatments where the radiation source is placed inside or very close to the target. In Episode...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've thoroughly covered external beam therapy. Now, we're shifting gears dramatically to explore treatments where the radiation source is placed inside or very close to the target. In Episode P15a: Brachytherapy Physics - Sources, Strength &amp; Dose Calculation, we'll introduce the common radioactive isotopes used, discuss how their strength is properly quantified, and meticulously break down the fundamental TG-43 formalism used for calculating dose around these sources.]]></itunes:summary><itunes:duration>1565</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>15</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P14b: Proton Therapy Physics &amp; Planning</title><link>https://www.spreaker.com/episode/physics-episode-p14b-proton-therapy-physics-planning--65575470</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P14a, we explored the world of electron beams. Now, in Episode P14b: Proton Therapy Physics &amp; Planning, we turn to the heavyweights: protons. Protons offer a unique dose deposition pattern, the Bragg peak, which allows for potentially superior sparing of normal tissues distal to the target. We'll delve into the physics behind proton interactions, how clinical beams are created, the critical challenge of range uncertainty, and specific planning considerations.]]></description><guid isPermaLink="false">b74e6dd4-efed-4e6b-a428-3c64381d0556</guid><pubDate>Sun, 06 Apr 2025 20:20:57 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575470/397927302_44100_2_48345eb50c97.mp3" length="28006334" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P14a, we explored the world of electron beams. Now, in Episode P14b: Proton Therapy Physics &amp;amp; Planning, we turn to the heavyweights: protons. Protons offer a unique dose deposition...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P14a, we explored the world of electron beams. Now, in Episode P14b: Proton Therapy Physics &amp; Planning, we turn to the heavyweights: protons. Protons offer a unique dose deposition pattern, the Bragg peak, which allows for potentially superior sparing of normal tissues distal to the target. We'll delve into the physics behind proton interactions, how clinical beams are created, the critical challenge of range uncertainty, and specific planning considerations.]]></itunes:summary><itunes:duration>1751</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>14</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P14a: Electron Beam Physics &amp; Planning</title><link>https://www.spreaker.com/episode/physics-episode-p14a-electron-beam-physics-planning--65575469</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! After exploring advanced photon techniques like IMRT, VMAT, and SRS/SBRT, we're now switching particle types. In Episode P14a: Electron Beam Physics &amp; Planning, we focus entirely on the clinical workhorse for treating shallow targets: the electron beam. We'll examine its unique depth dose characteristics, how its shape changes with depth, planning considerations, and clinical uses.]]></description><guid isPermaLink="false">6c652335-ccd1-4600-b505-e2911bfacc83</guid><pubDate>Sun, 06 Apr 2025 20:19:19 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575469/397927207_44100_2_cbe895d8da26c.mp3" length="24533511" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! After exploring advanced photon techniques like IMRT, VMAT, and SRS/SBRT, we're now switching particle types. In Episode P14a: Electron Beam Physics &amp;amp; Planning, we focus entirely on the...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! After exploring advanced photon techniques like IMRT, VMAT, and SRS/SBRT, we're now switching particle types. In Episode P14a: Electron Beam Physics &amp; Planning, we focus entirely on the clinical workhorse for treating shallow targets: the electron beam. We'll examine its unique depth dose characteristics, how its shape changes with depth, planning considerations, and clinical uses.]]></itunes:summary><itunes:duration>1534</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>14</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Episode P13b: Stereotactic Techniques (SRS &amp; SBRT Physics &amp; Delivery)</title><link>https://www.spreaker.com/episode/episode-p13b-stereotactic-techniques-srs-sbrt-physics-delivery--65575439</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P13a, we covered the principles of IMRT and VMAT for delivering conformal dose distributions. Today, in Episode P13b: Stereotactic Techniques, we push the boundaries of precision even further. We'll explore Stereotactic Radiosurgery (SRS) for the brain and Stereotactic Body Radiation Therapy (SBRT), also known as SABR, for targets outside the brain. These techniques deliver highly focused, often ablative doses with extreme accuracy, demanding specialized equipment and meticulous physics support.]]></description><guid isPermaLink="false">2ecd0b67-019c-4d93-8e06-ab83a5b47bed</guid><pubDate>Sun, 06 Apr 2025 20:17:08 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575439/397927099_44100_2_2944f70c13219.mp3" length="20199274" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P13a, we covered the principles of IMRT and VMAT for delivering conformal dose distributions. Today, in Episode P13b: Stereotactic Techniques, we push the boundaries of precision even further....</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P13a, we covered the principles of IMRT and VMAT for delivering conformal dose distributions. Today, in Episode P13b: Stereotactic Techniques, we push the boundaries of precision even further. We'll explore Stereotactic Radiosurgery (SRS) for the brain and Stereotactic Body Radiation Therapy (SBRT), also known as SABR, for targets outside the brain. These techniques deliver highly focused, often ablative doses with extreme accuracy, demanding specialized equipment and meticulous physics support.]]></itunes:summary><itunes:duration>1263</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P13a: Intensity Modulated Therapy (IMRT &amp; VMAT Principles, QA)</title><link>https://www.spreaker.com/episode/physics-episode-p13a-intensity-modulated-therapy-imrt-vmat-principles-qa--65575397</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P12b, we defined the crucial ICRU target volumes (GTV, CTV, PTV). Now, how do we deliver dose that conforms tightly to those volumes, especially when they're complex shapes wrapped around sensitive organs? In Episode P13a: Intensity Modulated Therapy (IMRT &amp; VMAT Principles, QA), we explore the sophisticated techniques of IMRT and VMAT that allow us to "dose paint" with remarkable precision, and the essential QA needed to ensure they work as planned.]]></description><guid isPermaLink="false">039ea71e-c6c7-4bb1-bc2b-d124025820cc</guid><pubDate>Sun, 06 Apr 2025 20:10:52 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575397/397926667_44100_2_da328e09a1089.mp3" length="28204446" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P12b, we defined the crucial ICRU target volumes (GTV, CTV, PTV). Now, how do we deliver dose that conforms tightly to those volumes, especially when they're complex shapes wrapped around...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P12b, we defined the crucial ICRU target volumes (GTV, CTV, PTV). Now, how do we deliver dose that conforms tightly to those volumes, especially when they're complex shapes wrapped around sensitive organs? In Episode P13a: Intensity Modulated Therapy (IMRT &amp; VMAT Principles, QA), we explore the sophisticated techniques of IMRT and VMAT that allow us to "dose paint" with remarkable precision, and the essential QA needed to ensure they work as planned.]]></itunes:summary><itunes:duration>1763</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>13</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P12b: Treatment Planning Volumes &amp; Concepts</title><link>https://www.spreaker.com/episode/physics-episode-p12b-treatment-planning-volumes-concepts--65575413</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P12a, we mastered the formulas for calculating Monitor Units to deliver a specific dose to a point. But radiation therapy treats volumes. How do we define these volumes precisely, accounting for not just the visible tumor but also microscopic spread and uncertainties in setup and motion? In Episode P12b: Treatment Planning Volumes &amp; Concepts, we introduce the standardized language defined by the ICRU (International Commission on Radiation Units and Measurements) for describing target volumes and organs at risk, laying the foundation for evaluating treatment plans.]]></description><guid isPermaLink="false">910074fa-3534-4d37-bdf4-1b1657fef5b5</guid><pubDate>Sun, 06 Apr 2025 18:27:45 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575413/397922155_44100_2_b7fc51f3cca7d.mp3" length="21061942" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P12a, we mastered the formulas for calculating Monitor Units to deliver a specific dose to a point. But radiation therapy treats volumes. How do we define these volumes precisely, accounting...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P12a, we mastered the formulas for calculating Monitor Units to deliver a specific dose to a point. But radiation therapy treats volumes. How do we define these volumes precisely, accounting for not just the visible tumor but also microscopic spread and uncertainties in setup and motion? In Episode P12b: Treatment Planning Volumes &amp; Concepts, we introduce the standardized language defined by the ICRU (International Commission on Radiation Units and Measurements) for describing target volumes and organs at risk, laying the foundation for evaluating treatment plans.]]></itunes:summary><itunes:duration>1317</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>12</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P12a: MU Calculations (SSD &amp; SAD Formulas)</title><link>https://www.spreaker.com/episode/physics-episode-p12a-mu-calculations-ssd-sad-formulas--65575441</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've gathered all the ingredients: Calibrated Output (CAL), Output Factors (Sc,p), Beam Modifiers (WF, TF), and Patient Attenuation Factors (PDD, TMR). Now, in Episode P12a: MU Calculations (SSD &amp; SAD Formulas), we finally put them together! We'll construct and explain the complete formulas used to calculate Monitor Units (MUs) for both common treatment techniques: fixed Source-to-Surface Distance (SSD) and isocentric Source-to-Axis Distance (SAD).]]></description><guid isPermaLink="false">9ba34146-aa8b-4db1-a4c2-eb59e2703f7f</guid><pubDate>Sun, 06 Apr 2025 18:26:36 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575441/397922119_44100_2_4d38bc8f77588.mp3" length="19604100" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! We've gathered all the ingredients: Calibrated Output (CAL), Output Factors (Sc,p), Beam Modifiers (WF, TF), and Patient Attenuation Factors (PDD, TMR). Now, in Episode P12a: MU Calculations (SSD...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! We've gathered all the ingredients: Calibrated Output (CAL), Output Factors (Sc,p), Beam Modifiers (WF, TF), and Patient Attenuation Factors (PDD, TMR). Now, in Episode P12a: MU Calculations (SSD &amp; SAD Formulas), we finally put them together! We'll construct and explain the complete formulas used to calculate Monitor Units (MUs) for both common treatment techniques: fixed Source-to-Surface Distance (SSD) and isocentric Source-to-Axis Distance (SAD).]]></itunes:summary><itunes:duration>1226</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>12</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P11: MU Calculation Components</title><link>https://www.spreaker.com/episode/physics-episode-p11-mu-calculation-components--65575442</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In Episode P10, we defined the key descriptors of dose distribution – PDD for SSD setups and TMR for SAD setups – which tell us how dose varies with depth, energy, and field size relative to a reference point (dmax). Now, in Episode P11: MU Calculation Components, we'll assemble the rest of the puzzle pieces needed to actually calculate the Monitor Units (MUs) required to deliver the prescribed dose. We'll focus on output factors (Sc, Sp), equivalent squares, and factors for beam modifiers like wedges and trays.]]></description><guid isPermaLink="false">9349dd58-1301-4a12-a34b-567713633121</guid><pubDate>Sun, 06 Apr 2025 18:25:40 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575442/397922081_44100_2_78938a63b71f8.mp3" length="19338278" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In Episode P10, we defined the key descriptors of dose distribution – PDD for SSD setups and TMR for SAD setups – which tell us how dose varies with depth, energy, and field size relative to a...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In Episode P10, we defined the key descriptors of dose distribution – PDD for SSD setups and TMR for SAD setups – which tell us how dose varies with depth, energy, and field size relative to a reference point (dmax). Now, in Episode P11: MU Calculation Components, we'll assemble the rest of the puzzle pieces needed to actually calculate the Monitor Units (MUs) required to deliver the prescribed dose. We'll focus on output factors (Sc, Sp), equivalent squares, and factors for beam modifiers like wedges and trays.]]></itunes:summary><itunes:duration>1209</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>11</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P10: EBRT Dose Descriptors</title><link>https://www.spreaker.com/episode/physics-episode-p10-ebrt-dose-descriptors--65575445</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P9, we mastered the art of calibration using TG-51, linking machine output (MU) to absolute dose under reference conditions. But patients aren't water phantoms treated at 10 cm depth with a 10x10 field! So, how does dose actually distribute within a patient? In Episode P10: External Beam Dose Descriptors (Part 1), we begin our dive into Chapter 12, focusing on key concepts like electron buildup, dmax, Percent Depth Dose (PDD), and the family of Tissue-Air/Phantom/Maximum Ratios (TAR, TPR, TMR) used to characterize dose distribution.]]></description><guid isPermaLink="false">bd2c8e27-17ae-412a-b8be-d949dab46c76</guid><pubDate>Sun, 06 Apr 2025 17:36:16 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575445/397919829_44100_2_aa96345cf8f1a.mp3" length="23470641" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P9, we mastered the art of calibration using TG-51, linking machine output (MU) to absolute dose under reference conditions. But patients aren't water phantoms treated at 10 cm depth with a...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P9, we mastered the art of calibration using TG-51, linking machine output (MU) to absolute dose under reference conditions. But patients aren't water phantoms treated at 10 cm depth with a 10x10 field! So, how does dose actually distribute within a patient? In Episode P10: External Beam Dose Descriptors (Part 1), we begin our dive into Chapter 12, focusing on key concepts like electron buildup, dmax, Percent Depth Dose (PDD), and the family of Tissue-Air/Phantom/Maximum Ratios (TAR, TPR, TMR) used to characterize dose distribution.]]></itunes:summary><itunes:duration>1467</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>10</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P9: TG-51 Calibration Essentials</title><link>https://www.spreaker.com/episode/physics-episode-p9-tg-51-calibration-essentials--65575420</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P8, we stressed the importance of Quality Assurance – making sure our LINACs work correctly. But QA relies on having an accurate baseline measurement of the machine's output. How do we establish that baseline? That's where Calibration comes in. Today, in Episode P9: Calibration Essentials, we'll demystify the process of calibrating a LINAC, focusing on the current standard protocol in the US: the AAPM's Task Group 51 report, or TG-51.]]></description><guid isPermaLink="false">70e5ee0d-fe0a-41b2-b2c9-5e3e3365d9e4</guid><pubDate>Sun, 06 Apr 2025 17:22:53 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575420/397919154_44100_2_752da21c9daa6.mp3" length="21508322" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P8, we stressed the importance of Quality Assurance – making sure our LINACs work correctly. But QA relies on having an accurate baseline measurement of the machine's output. How do we...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P8, we stressed the importance of Quality Assurance – making sure our LINACs work correctly. But QA relies on having an accurate baseline measurement of the machine's output. How do we establish that baseline? That's where Calibration comes in. Today, in Episode P9: Calibration Essentials, we'll demystify the process of calibrating a LINAC, focusing on the current standard protocol in the US: the AAPM's Task Group 51 report, or TG-51.]]></itunes:summary><itunes:duration>1345</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>9</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P8b: Quality Assurance (QA) for Linacs &amp; Simulators</title><link>https://www.spreaker.com/episode/physics-episode-p8b-quality-assurance-qa-for-linacs-simulators--65575426</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P8a, we discussed Beam Quality – how penetrating our radiation beams are. Now, in Episode P8b: Quality Assurance (QA) for Linacs &amp; Simulators, we tackle the absolutely essential processes that ensure these powerful and complex machines operate correctly and safely every single day. We'll explore the key QA tests, frequencies, and tolerances based on AAPM Task Group reports, focusing on keeping our treatments accurate and our patients safe.]]></description><guid isPermaLink="false">79fca5b1-c0c0-43fd-8524-5a2d16e8a775</guid><pubDate>Sun, 06 Apr 2025 17:14:21 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575426/397918694_44100_2_f11b8bd58bd65.mp3" length="21354931" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P8a, we discussed Beam Quality – how penetrating our radiation beams are. Now, in Episode P8b: Quality Assurance (QA) for Linacs &amp;amp; Simulators, we tackle the absolutely essential processes...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P8a, we discussed Beam Quality – how penetrating our radiation beams are. Now, in Episode P8b: Quality Assurance (QA) for Linacs &amp; Simulators, we tackle the absolutely essential processes that ensure these powerful and complex machines operate correctly and safely every single day. We'll explore the key QA tests, frequencies, and tolerances based on AAPM Task Group reports, focusing on keeping our treatments accurate and our patients safe.]]></itunes:summary><itunes:duration>1335</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>8</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P8a to the Beam Quality &amp; Characteristics</title><link>https://www.spreaker.com/episode/physics-episode-p8a-to-the-beam-quality-characteristics--65575446</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! After diving deep into dosimetry detectors and concepts in P7a and P7b, we now turn our focus in Episode P8a to the Beam Quality &amp; Characteristics. How do we objectively describe the penetrating power of our radiation beams? What factors influence this quality? We'll explore concepts like Half-Value Layer (HVL), beam hardening, and how quality is specified for both kilovoltage and megavoltage beams.]]></description><guid isPermaLink="false">67164870-31d3-4a12-a961-4c816c084886</guid><pubDate>Sun, 06 Apr 2025 17:11:30 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575446/397918589_44100_2_b0f4fcdaba3ec.mp3" length="22745063" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! After diving deep into dosimetry detectors and concepts in P7a and P7b, we now turn our focus in Episode P8a to the Beam Quality &amp;amp; Characteristics. How do we objectively describe the...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! After diving deep into dosimetry detectors and concepts in P7a and P7b, we now turn our focus in Episode P8a to the Beam Quality &amp; Characteristics. How do we objectively describe the penetrating power of our radiation beams? What factors influence this quality? We'll explore concepts like Half-Value Layer (HVL), beam hardening, and how quality is specified for both kilovoltage and megavoltage beams.]]></itunes:summary><itunes:duration>1422</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>8</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P7b: Bragg-Gray Theory &amp; The Dosimetry Toolkit</title><link>https://www.spreaker.com/episode/physics-episode-p7b-bragg-gray-theory-the-dosimetry-toolkit--65575449</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P7a, we established the concept of Exposure, detailed the ionization chamber, and learned how the f-factor converts exposure-in-air to dose-in-medium. But how can we be sure that measuring ionization in that tiny air cavity inside our water phantom accurately tells us the dose in the water? That's the focus of the first part of Episode P7b: Bragg-Gray Theory &amp; The Dosimetry Toolkit. We'll unravel this fundamental theory and then survey the rest of the physicist's toolkit – the various detectors beyond the ion chamber used for different measurement tasks.]]></description><guid isPermaLink="false">fe52688a-98a3-465f-863e-bcba38e44540</guid><pubDate>Sun, 06 Apr 2025 17:09:13 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575449/397918481_44100_2_f45572b743b3b.mp3" length="30930376" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P7a, we established the concept of Exposure, detailed the ionization chamber, and learned how the f-factor converts exposure-in-air to dose-in-medium. But how can we be sure that measuring...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P7a, we established the concept of Exposure, detailed the ionization chamber, and learned how the f-factor converts exposure-in-air to dose-in-medium. But how can we be sure that measuring ionization in that tiny air cavity inside our water phantom accurately tells us the dose in the water? That's the focus of the first part of Episode P7b: Bragg-Gray Theory &amp; The Dosimetry Toolkit. We'll unravel this fundamental theory and then survey the rest of the physicist's toolkit – the various detectors beyond the ion chamber used for different measurement tasks.]]></itunes:summary><itunes:duration>1934</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>7</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P7a: Measuring Dose - Exposure, Ion Chambers &amp; The f-factor</title><link>https://www.spreaker.com/episode/physics-episode-p7a-measuring-dose-exposure-ion-chambers-the-f-factor--65575471</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P6, we saw how photons interact – PE, Compton, Pair Production. Now we need to quantify the result: dose. In Episode P7a: Measuring Dose - Exposure, Ion Chambers &amp; The f-factor, we'll start this journey. We'll cover the historical concept of Exposure, dive deep into the workhorse detector – the Ionization Chamber, and introduce the crucial 'f-factor' that bridges the gap between measuring ionization in air and understanding dose in tissue.]]></description><guid isPermaLink="false">25fedf2d-a0a5-4665-90d8-27f0e16f082d</guid><pubDate>Sun, 06 Apr 2025 17:07:45 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575471/397918314_44100_2_1c985bff6dbb8.mp3" length="23463117" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P6, we saw how photons interact – PE, Compton, Pair Production. Now we need to quantify the result: dose. In Episode P7a: Measuring Dose - Exposure, Ion Chambers &amp;amp; The f-factor, we'll...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P6, we saw how photons interact – PE, Compton, Pair Production. Now we need to quantify the result: dose. In Episode P7a: Measuring Dose - Exposure, Ion Chambers &amp; The f-factor, we'll start this journey. We'll cover the historical concept of Exposure, dive deep into the workhorse detector – the Ionization Chamber, and introduce the crucial 'f-factor' that bridges the gap between measuring ionization in air and understanding dose in tissue.]]></itunes:summary><itunes:duration>1467</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>7</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P6: Photon Interactions &amp; Basic Dose Concepts</title><link>https://www.spreaker.com/episode/physics-episode-p6-photon-interactions-basic-dose-concepts--65575407</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P5, we explored the powerful machines, especially LINACs, that generate high-energy photon (X-ray) beams. Now that we have these beams, what happens when they actually hit the patient? In Episode P6: Photon Interactions &amp; Basic Dose Concepts, we'll uncover how these energetic photons interact with matter, transfer their energy, and lead to the concepts of Kerma and Absorbed Dose.]]></description><guid isPermaLink="false">8fa61a4e-8732-4d8b-b96f-65e346357441</guid><pubDate>Sun, 06 Apr 2025 17:05:21 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575407/397918138_44100_2_87df4ccc53c67.mp3" length="24478758" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P5, we explored the powerful machines, especially LINACs, that generate high-energy photon (X-ray) beams. Now that we have these beams, what happens when they actually hit the patient? In...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P5, we explored the powerful machines, especially LINACs, that generate high-energy photon (X-ray) beams. Now that we have these beams, what happens when they actually hit the patient? In Episode P6: Photon Interactions &amp; Basic Dose Concepts, we'll uncover how these energetic photons interact with matter, transfer their energy, and lead to the concepts of Kerma and Absorbed Dose.]]></itunes:summary><itunes:duration>1530</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>6</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P5: High Energy Treatment Machines</title><link>https://www.spreaker.com/episode/physics-episode-p5-high-energy-treatment-machines--65575406</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! Last episode, P4, we learned how kV X-rays are produced in tubes. Today, we're powering up significantly in Episode P5: High Energy Treatment Machines. We'll explore the historical Cobalt-60 units and then spend most of our time dissecting the modern workhorse of radiation oncology: the Linear Accelerator, or LINAC. We'll journey through its complex components, from generating electrons to shaping the final treatment beam.]]></description><guid isPermaLink="false">305c91a7-daa8-4ec4-b915-8287839dfa7b</guid><pubDate>Sun, 06 Apr 2025 07:42:35 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575406/397900527_44100_2_5da8e0192521c.mp3" length="27061328" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! Last episode, P4, we learned how kV X-rays are produced in tubes. Today, we're powering up significantly in Episode P5: High Energy Treatment Machines. We'll explore the historical Cobalt-60...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! Last episode, P4, we learned how kV X-rays are produced in tubes. Today, we're powering up significantly in Episode P5: High Energy Treatment Machines. We'll explore the historical Cobalt-60 units and then spend most of our time dissecting the modern workhorse of radiation oncology: the Linear Accelerator, or LINAC. We'll journey through its complex components, from generating electrons to shaping the final treatment beam.]]></itunes:summary><itunes:duration>1692</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>5</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P4: kV X-ray Production</title><link>https://www.spreaker.com/episode/physics-episode-p4-kv-x-ray-production--65575410</link><description><![CDATA[Welcome back to RadOnc Smart Review, Physics Series! In P3, we saw how charged particles like electrons lose energy interacting with matter. Today, in Episode P4: kV X-ray Production, we harness those interactions! We'll focus specifically on how we generate kilovoltage (kV) X-rays, the kind used ubiquitously in diagnostic imaging (like CT and cone-beam CT) and historically in orthovoltage therapy. We'll dissect the X-ray tube and the physics behind creating those useful photons.]]></description><guid isPermaLink="false">0247fa74-ab0d-48a4-9f8e-4fd6f0f2c6f9</guid><pubDate>Sun, 06 Apr 2025 07:40:14 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575410/397900475_44100_2_6f1a48496bb5c.mp3" length="22380603" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to RadOnc Smart Review, Physics Series! In P3, we saw how charged particles like electrons lose energy interacting with matter. Today, in Episode P4: kV X-ray Production, we harness those interactions! We'll focus specifically on how we...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to RadOnc Smart Review, Physics Series! In P3, we saw how charged particles like electrons lose energy interacting with matter. Today, in Episode P4: kV X-ray Production, we harness those interactions! We'll focus specifically on how we generate kilovoltage (kV) X-rays, the kind used ubiquitously in diagnostic imaging (like CT and cone-beam CT) and historically in orthovoltage therapy. We'll dissect the X-ray tube and the physics behind creating those useful photons.]]></itunes:summary><itunes:duration>1399</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>4</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P3: Particulate Interactions</title><link>https://www.spreaker.com/episode/physics-episode-p3-particulate-interactions--65575472</link><description><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P2, we explored radioactive decay, where unstable nuclei emit particles like alphas and betas. Now, in Episode P3: Particulate Interactions, we'll follow those particles – and others like electrons and protons accelerated in our machines, plus neutrons – as they travel through matter. How do they lose energy? What factors determine how far they go? And what makes protons deposit their dose so differently?]]></description><guid isPermaLink="false">1b4aaa03-a9aa-45a9-86d1-2dbfa4a64bbf</guid><pubDate>Sun, 06 Apr 2025 07:37:20 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575472/397900408_44100_2_05253d90f857c.mp3" length="22837432" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to the RadOnc Smart Review Physics Series! In P2, we explored radioactive decay, where unstable nuclei emit particles like alphas and betas. Now, in Episode P3: Particulate Interactions, we'll follow those particles – and others like...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to the RadOnc Smart Review Physics Series! In P2, we explored radioactive decay, where unstable nuclei emit particles like alphas and betas. Now, in Episode P3: Particulate Interactions, we'll follow those particles – and others like electrons and protons accelerated in our machines, plus neutrons – as they travel through matter. How do they lose energy? What factors determine how far they go? And what makes protons deposit their dose so differently?]]></itunes:summary><itunes:duration>1428</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>3</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Physics Episode P2 Radioactive Decay</title><link>https://www.spreaker.com/episode/physics-episode-p2-radioactive-decay--65575476</link><description><![CDATA[Welcome back to RadOnc Smart Review, Physics Series! Last time, in P1, we looked at the atom's structure and what happens when electrons get shuffled around. Today, in Episode P2: Radioactive Decay, we're focusing on the nucleus itself and what happens when it's unstable. We'll cover the different ways nuclei decay, how we measure that decay, and what happens when radioactive parents produce radioactive daughters.]]></description><guid isPermaLink="false">c3f43653-1582-41e3-be41-964a865812a8</guid><pubDate>Sun, 06 Apr 2025 07:35:34 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575476/397900389_44100_2_056153c8dde5a.mp3" length="26084557" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome back to RadOnc Smart Review, Physics Series! Last time, in P1, we looked at the atom's structure and what happens when electrons get shuffled around. Today, in Episode P2: Radioactive Decay, we're focusing on the nucleus itself and what...</itunes:subtitle><itunes:summary><![CDATA[Welcome back to RadOnc Smart Review, Physics Series! Last time, in P1, we looked at the atom's structure and what happens when electrons get shuffled around. Today, in Episode P2: Radioactive Decay, we're focusing on the nucleus itself and what happens when it's unstable. We'll cover the different ways nuclei decay, how we measure that decay, and what happens when radioactive parents produce radioactive daughters.]]></itunes:summary><itunes:duration>1631</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>2</itunes:episode><itunes:episodeType>full</itunes:episodeType></item><item><title>Episode P1: Atomic &amp; Nuclear Structure</title><link>https://www.spreaker.com/episode/episode-p1-atomic-nuclear-structure--65575477</link><description><![CDATA[Welcome to RadOnc Smart Review, the podcast dedicated to sharpening your radiation oncology expertise. This is the very first episode of our Physics Series, P1: Atomic and Nuclear Structure. Today, we're going back to the absolute basics, the tiny building blocks that underpin everything we do in radiation therapy. We'll cover the fundamental particles, electron shells, binding energy, and what happens when things get knocked out of place. Ready to build our foundation?]]></description><guid isPermaLink="false">32820eb9-eb9e-477d-be0e-f1e1f2040256</guid><pubDate>Sun, 06 Apr 2025 07:29:20 +0000</pubDate><enclosure url="https://api.spreaker.com/download/episode/65575477/397900274_44100_2_634d386eff60f.mp3" length="27036250" type="audio/mpeg"/><itunes:author>Abass Conteh</itunes:author><itunes:subtitle>Welcome to RadOnc Smart Review, the podcast dedicated to sharpening your radiation oncology expertise. This is the very first episode of our Physics Series, P1: Atomic and Nuclear Structure. Today, we're going back to the absolute basics, the tiny...</itunes:subtitle><itunes:summary><![CDATA[Welcome to RadOnc Smart Review, the podcast dedicated to sharpening your radiation oncology expertise. This is the very first episode of our Physics Series, P1: Atomic and Nuclear Structure. Today, we're going back to the absolute basics, the tiny building blocks that underpin everything we do in radiation therapy. We'll cover the fundamental particles, electron shells, binding energy, and what happens when things get knocked out of place. Ready to build our foundation?]]></itunes:summary><itunes:duration>1690</itunes:duration><itunes:explicit>false</itunes:explicit><itunes:image href="https://d3wo5wojvuv7l.cloudfront.net/t_rss_itunes_square_1400/images.spreaker.com/original/1db0bdc4b5d27f9c2aba928561feeaf2.jpg"/><itunes:season>1</itunes:season><itunes:episode>1</itunes:episode><itunes:episodeType>full</itunes:episodeType></item></channel></rss>
