All available episodes. Inner Sanctum was a hugely popular Old Time Radio series created by producer Himan Brown. It was based on the popular Inner Sanctum mystery series of books. It aired from January 7, 1941, to October 5, 1952. Inner Sanctum featured tales of mystery, horror and suspense, with a mix of humor. That humor was what made Inner Sanctum different from similar horror and mystery series like Suspense, or The Whistler aired during the golden age of radio. Each episode started with the sound of a creaking door, some creepy organ music, followed by the opening narration. It's been said that the listening to the show was like celebrating Halloween every week. Many established stars played roles or were guest stars in the series, including Peter Lorre, Helen Hayes, Mary Astor, Frank Sinatra, Bela Lugosi and Orson Welles. Of the several hundred episodes of Inner Sanctum that aired, only about 150 survived.