We spend an hour in the last two minutes of the fourth quarter, behind and desperate, with people trying any damn thing they can think of. Visit thisamericanlife.org/lifepartners to sign up for our premium subscription.

• Prologue: Five years after Ora first started experiencing mysterious and debilitating health problems, she decides to try a treatment that she knows very well might kill her. Host Ira Glass talks to her about the experience. (9 minutes)
• Act One: Two lawyers have just 3 months to stop their client's execution. In Texas, where this story takes place, these kinds of appeals to get people off death row fail 94% of the time. (38 minutes)
• Act Two: At the Otay Mesa Detention Center in San Diego, migrants figured out an ingenious way to communicate with the activists gathered outside of the detention center’s walls. (13 minutes)

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(Updated for each story)